Abstracts tagged "Ankylosing spondylitis (AS)"

Abstract Number: L13 • 2018 ACR/ARHP Annual Meeting
Long-Term Evaluation of Secukinumab in Ankylosing Spondylitis: 5 Year Efficacy and Safety Results from a Phase 3 Trial
Xenofon Baraliakos¹, Jürgen Braun², Atul A. Deodhar³, Denis Poddubnyy⁴, Alan J. Kivitz⁵, Hasan Tahir⁶, Filip van Den Bosch⁷, Evie Maria Delicha⁸, Zsolt Talloczy⁹ and Anke Fierlinger⁹, ¹Rheumazentrum Ruhrgebiet, Herne, and Ruhr University Bochum, Herne, Germany, Herne, Germany, ²Rheumazentrum Ruhrgebiet Herne, and Ruhr University Bochum, Herne, Germany, Herne, Germany, ³Oregon Health & Science University, Portland, Portland, OR, ⁴Rheumatology, Campus Benjamin Franklin Charité – Universitätsmedizin, Germany and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, ⁵Altoona Arthritis & Osteoporosis Center, Duncansville, PA, ⁶Whipps Cross University Hospital, Barts Health NHS Trust, London, United Kingdom, ⁷Rheumatology, Universitair Ziekenhuis, Ghent, Belgium, Gent, Belgium, ⁸Novartis Pharma AG, Basel, Basel, Switzerland, ⁹Novartis Pharmaceuticals Corporation, East Hanover, New Jersey, United States, East Hanover, NJ
Background/Purpose: Clinical evaluation of efficacy and safety for long-term treatment for ankylosing spondylitis (AS) is important for treatment decision-making. Secukinumab (SEC), a fully human mAb…
Abstract Number: 285 • 2018 ACR/ARHP Annual Meeting
Inflammatory Bowel Disease Is Associated with a Substantial Economic Burden in Patients with Psoriatic Arthritis and in Patients with Ankylosing Spondylitis
Martin J. Bergman¹, Patrick Zueger², Jinlin Song³, Irina Pivneva⁴, Keith A. Betts³ and Avani D. Joshi⁵, ¹Drexel University College of Medicine, Philadelphia, PA, ²AbbVie Inc., North Chicago, IL, ³Analysis Group, Inc., Los Angeles, CA, ⁴Analysis Group, Inc., Montreal, QC, Canada, ⁵AbbVie, Inc., North Chicago, IL
Background/Purpose: Psoriatic arthritis (PsA) and ankylosing spondylitis (AS) belong to a group of inflammatory arthritides known to share similar extra-articular manifestations, such as inflammatory bowel…
Abstract Number: 691 • 2018 ACR/ARHP Annual Meeting
A Service Evaluation of Reporting Standards of Computer Tomography Defined Sacroiliitis Suggestive of Axial Spondyloarthritis in Inflammatory Bowel Disease Patients Imaged for Non-Musculoskeletal Indications
Chong Seng Edwin Lim¹, Samantha Bee Lian Low², Baljeet Dhillon², Shin Azegami², Andoni Paul Toms² and Karl Gaffney¹, ¹Rheumatology, Norfolk and Norwich University Hospital, Norwich, United Kingdom, ²Radiology, Norfolk and Norwich University Hospital, Norwich, United Kingdom
Background/Purpose: A combined service evaluation by the rheumatology and radiology department was undertaken to understand the frequency and reporting standards of Computer Tomography-defined Sacroiliitis (CTSI)…
Abstract Number: 1623 • 2018 ACR/ARHP Annual Meeting
Insight into the Quality of Life of Patients with Ankylosing Spondylitis: Real-World Data from a US-Based Life Impact Survey
James T. Rosenbaum¹, Lisa Pisenti², Yujin Park³ and Richard Howard⁴, ¹Ophthalmology, Oregon Health & Science University and Legacy Devers Eye Institute, Portland, OR, ²UCB, Inc., Smyrna, GA, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁴Spondylitis Association of America, Van Nuys, CA
Background/Purpose: While severe pain and stiffness are common hallmarks of ankylosing spondylitis (AS), disease progression is slow and not always visible; however, the quality of…
Abstract Number: 2396 • 2018 ACR/ARHP Annual Meeting
Reduction in the Utilization of Prednisone and/or Methotrexate Following the Initiation of Etanercept in Pediatric Patients
Majed M M Khraishi¹, Brad Millson², John Woolcott³, Lisa Marshall⁴ and Heather Jones⁴, ¹Memorial University of Newfoundland, St John's, NF, Canada, ²IQVIA, Kanata, ON, Canada, ³Global Outcomes & Evidence, Pfizer, Collegeville, PA, ⁴Pfizer, Collegeville, PA
Background/Purpose: In Canada, the pediatric indications of etanercept (ETN) are active ankylosing spondylitis (AS), plaque psoriasis (PsO) and moderate to severely active juvenile idiopathic arthritis…
Abstract Number: 311 • 2018 ACR/ARHP Annual Meeting
Magnetic Resonance Imaging of the Cervical Spine in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis Presenting with Chronic Neck Pain – a Systematic Comparison of Clinical Assessments
Xenofon Baraliakos¹, Mina Soltani², Parham Damirchi², Uta Kiltz³ and Jürgen Braun¹, ¹Ruhr-University Bochum, Herne, Germany, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Rheumatology, Rheumazentrum Ruhrgebiet, Herne, and Ruhr University Bochum, Herne, Germany
Background/Purpose: Despite the differences in pathogenesis, neck pain associated with functional limitation of the cervical spine is a frequent clinical symptom of patients with rheumatoid…
Abstract Number: 836 • 2018 ACR/ARHP Annual Meeting
Genetic Risk Score Prediction in Ankylosing Spondylitis
Zhixiu Li¹, Erika De Guzman¹, Jessica Harris¹, Nurullah Akkoc², Mahdi Mahmoudi³, Maxime Breban⁴, Chung-Tei Chou⁵, Michael Weisman⁶, Lianne S. Gensler⁷, Michael Ward⁸, Mohammad H. Rahbar⁹, Laura A. Diekman¹⁰, Tae-Hwan Kim¹¹, Paul Leo¹, John D. Reveille¹⁰, Paul Wordsworth¹², Matthew Brown¹ and Huji Xu¹³, ¹Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Translational Research Institute, Brisbane, Australia, Brisbane, Australia, ²Rheumatology, İzmir, Turkey, İzmir, Turkey, ³Rheumatology Research Center, Tehran University of Medical Sciences, Tehran, Iran, Tehran, Iran (Islamic Republic of), ⁴Hôpital Ambroise Paré, Assistance Publique-Hôpitaux de Paris, Boulogne, France, Boulogne, France, ⁵Division of Allergy-Immunology-Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Taipei, Taiwan, ⁶Cedars-Sinai Medical Center, Los Angeles, CA, USA, Los Angeles, CA, ⁷University of California San Francisco, San Francisco, CA, ⁸National Institutes of Health, Bethesda, MD, USA, Bethesda, MD, ⁹Biostatistics/Epidemiology/Research Design (BERD) Core | Center for Clinical and Translational Sciences, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX, ¹⁰Rheumatology, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX, ¹¹Rheumatology, The Hospital for Rheumatic Diseases, Hanyang University, Seoul, Korea, Seoul, Korea, Republic of (South), ¹²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK, Oxford, United Kingdom, ¹³School of Clinical Medicine, Tsinghua University, Beijing, China, Beijing, China
Background/Purpose: The diagnosis of ankylosing spondylitis (AS) is delayed by on average 8–11 years after the onset of symptoms, and there is increasing evidence that…
Abstract Number: 1624 • 2018 ACR/ARHP Annual Meeting
Real-World Insight into the Disease Burden and Treatment of Spondyloarthritis from a US-Based Life Impact Survey
James T. Rosenbaum¹, Lisa Pisenti², Yujin Park³ and Richard Howard⁴, ¹Ophthalmology, Oregon Health & Science University and Legacy Devers Eye Institute, Portland, OR, ²UCB, Inc., Smyrna, GA, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁴Spondylitis Association of America, Van Nuys, CA
Background/Purpose: Spondyloarthritis (SpA) is a group of chronic, inflammatory diseases associated with severe pain in the joints and entheses. There is limited evidence on real-world…
Abstract Number: 2430 • 2018 ACR/ARHP Annual Meeting
Pregnancy in Women with Ankylosing Spondylitis Is Not Associated with Poor Obstetric Outcomes: Analysis of Nationwide Inpatient Sample Database 2003-2011
Vikas Majithia and Shweta Kishore, Division of Rheumatology, University of Mississippi Medical Center, Jackson, MS
Background/Purpose: Outcomes of pregnancy are well studied in a number of rheumatic diseases such as Rheumatoid Arthritis (RA) and systemic lupus erythematosus. When compared, there…
Abstract Number: 316 • 2018 ACR/ARHP Annual Meeting
Eligibility Rates in Axial Spondyloarthritis Clinical Trials Based on Imaging Criteria
Farhan A. Syed¹, David Bennett¹, Michael O'Connor¹, Gabriele Pradella² and Sarah Warner¹, ¹Scientific and Medical Services, PAREXEL International, Billerica, MA, ²Image Management, PAREXEL International, Billerica, MA
Background/Purpose: Axial Spondyloarthritis (AxSpA) encompasses both non-radiographic (nr-AxSpA) as well as radiographic ankylosing spondylitis (AS) which displays structural changes at the sacro-iliac joint (SIJ). Phase…
Abstract Number: 892 • 2018 ACR/ARHP Annual Meeting
Establishing the Minimal Clinically Important Difference (MCID) for the Ankylosing Spondylitis Quality of Life Questionnaire (ASQoL)
Nicolas Richard¹, Nigil Haroon², George Tomlinson³, Ismail Sari¹, Zahi Touma⁴ and Robert D Inman¹, ¹Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ²Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada, ⁴University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: The Ankylosing Spondylitis Quality of Life (ASQoL) is a readable and simple to complete questionnaire relating to health-related quality of life (HRQoL) in subjects…
Abstract Number: 1628 • 2018 ACR/ARHP Annual Meeting
Is Axial Psoriatic Arthritis Distinct from Ankylosing Spondylitis with and without Concomitant Psoriasis?
Joy Feld¹, Justine Y. Ye², Vinod Chandran², Robert D Inman³, Nigil Haroon⁴, Richard J. Cook⁵ and Dafna D Gladman¹, ¹Toronto Psoriatic Arthritis Research Program, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ⁴Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, Toronto, ON, Canada, ⁵Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada
Background/Purpose: Spondyloarthritis include two major phenotypes: ankylosing spondylitis (AS) and psoriatic arthritis (PsA). 10% of AS patients have concomitant psoriasis, while 25% - 70% of…
Abstract Number: 2431 • 2018 ACR/ARHP Annual Meeting
Birth Outcomes and Disease Activity during Pregnancy in a Prospective Cohort of Women with Psoriatic Arthritis and Ankylosing Spondylitis
Chelsey J F Smith¹, Arthur Kavanaugh² and Christina D Chambers³, ¹Rheumatology, University of California San Diego, La Jolla, CA, ²University of California, San Diego, School of Medicine, La Jolla, CA, ³University of California San Diego Department of Pediatrics, La Jolla, CA
Background/Purpose: The goal of this prospective cohort study is to add to the limited data on birth outcomes in psoriatic arthritis (PsA) and ankylosing spondylitis…
Abstract Number: 450 • 2018 ACR/ARHP Annual Meeting
Injection Site Reaction Associated with Subcutaneous Biologic Agents and Methotrexate. Analysis from the Rhumadata® Clinical Database and Registry
Denis Choquette¹, Louis Bessette², Jacques Brown², Boulos Haraoui¹, Frédéric Massicotte¹, Jean-Pierre Pelletier¹, Jean-Pierre Raynauld¹, Marie-Anaïs Rémillard¹, Diane Sauvageau¹, Angèle Turcotte², Édith Villeneuve¹ and Louis Coupal¹, ¹Rheumatology, Institut de Recherche en Rhumatologie de Montréal (IRRM), Montréal, QC, Canada, ²Rheumatology, Centre de l'Ostéoporose et de Rhumatologie de Québec (CORQ), Québec, QC, Canada
Background/Purpose: Injection Site Reaction (ISRs) are associated with the subcutaneous (SC) route of administration of all biologic agents, and 3% to 15% of patients reports…
Abstract Number: 894 • 2018 ACR/ARHP Annual Meeting
Cancer Risk in Ankylosing Spondylitis in United States Medicare Beneficiaries: Detection of a Chronic Non Steroidal Anti-Inflammatory Drug Use Signature
Sara Alehashemi¹ and Michael Ward², ¹Rheumatology, National Institutes of Health, Bethesda, MD, ²National Institutes of Health, Bethesda, MD, USA, Bethesda, MD
Background/Purpose: Few studies have examined risk of cancer in ankylosing spondylitis (AS) since the end of the radiation therapy era. With greater use of biologics,…

1
2
3
…
31
Next Page »