Abstract Number: 1373 • ACR Convergence 2020
IL-23 Skin and Joint Profiling in Psoriatic Arthritis: Novel Perspectives in Understanding Clinical Responses to IL-23 Inhibitors
Background/Purpose: PsA is a chronic heterogeneous inflammatory condition affecting up to 30% of patients with skin and/or nail psoriasis and the IL-23/IL-17 axis is believed…Abstract Number: 0099 • ACR Convergence 2020
Interleukin 6 Concentration in Synovial Fluid of Patients with Different Types of Arthritis
Background/Purpose: Persistent synovitis without known markers such as rheumatoid factor (RF), anti-citrullinated protein antibodies (ACPA) as well as without genetic markers as HLAB27 is not…Abstract Number: 1410 • ACR Convergence 2020
Resident Memory T Cells Persist in Joints of Anakinra-Treated Mice in Spontaneous Arthritis Model
Background/Purpose: Inflammatory arthritis is characterized by chronic inflammation of joints which can be suppressed with immunomodulatory therapy. However, two-thirds of patients will have an arthritis…Abstract Number: 0312 • ACR Convergence 2020
Dactylitis Is Associated with Greater Disease Severity, Ultrasound Synovitis, and Erosive Damage, in Very Early DMARD Naïve Psoriatic Arthritis
Background/Purpose: Dactylitis is a hallmark feature of Psoriatic arthritis (PsA), defined as a uniform swelling of a finger or toe (“sausage digit”). It is associated…Abstract Number: 1547 • ACR Convergence 2020
Role of Artificial Intelligence in Assessment of Peripheral Joint MRI in Inflammatory Arthritis: A Systematic Review and Meta-analysis
Background/Purpose: To summarize the feasibility, reliability, and validity of computer-aided quantification of joint destruction and synovitis on MRI using artificial intelligence (AI) based methods in…Abstract Number: 0313 • ACR Convergence 2020
Swollen Joints but Not Tender Joints Are Associated with Ultrasound Power Doppler Synovitis in Very Early DMARD Naive Psoriatic Arthritis
Background/Purpose: Clinical tender and swollen joint counts are used for biologic drug eligibility and clinical trial inclusion criteria. Ultrasonography (US) adds to clinical examination as…Abstract Number: 1551 • ACR Convergence 2020
Rapid Effect of Tofacitinib in Reducing US Joint and Tendon Inflammatory Lesions of RA Patients: Data from a 24 Weeks Longitudinal Study
Background/Purpose: To explore the effects of tofacitinib (Tofa) on US lesions in a consecutive series of patients with active RA MTX and/or bioDMARDs -IR. Methods: In…Abstract Number: 0481 • ACR Convergence 2020
Subclinical Synovitis in Arthralgia: How Often Does It Result in Clinical Arthritis? A Longitudinal Study to Reflect on Starting Points for DMARD Treatment
Background/Purpose: According to guidelines, clinical arthritis is mandatory for diagnosing rheumatoid arthritis (RA). However, in the absence of clinical synovitis, imaging-detected subclinical synovitis is increasingly…Abstract Number: 1562 • ACR Convergence 2020
Subclinical Joint Inflammation of Hands by Magnetic Resonance Imaging in Patients with Psoriatic Arthritis in Clinical Remission Compared to Active Disease
Background/Purpose: Assessment of disease activity in psoriatic arthritis (PsA) is based on tender and swollen joint counts (TJC and SJC, respectively). Yet, the prevalence of…Abstract Number: 1164 • 2019 ACR/ARP Annual Meeting
Novel Computer Assisted Methodology for Quantitative Assessment of MRI Treatment Responses to Apremilast in Patients with Psoriatic Arthritis
Background/Purpose: Response to treatment in Psoriatic Arthritis (PsA) can be captured using the OMERACT PsA Magnetic Resonance Imaging Score (PsAMRIS). While reliable and valid, PsAMRIS…Abstract Number: 1982 • 2019 ACR/ARP Annual Meeting
Senescent Synoviocytes in Knee Osteoarthritis Correlate with Disease Biomarkers, Synovitis, and Knee Pain
Background/Purpose: Background/Purpose: Cellular senescence is a natural state in which a cell permanently halts division through upregulation of a set of intracellular proteins including p16INK4A…Abstract Number: 1993 • 2019 ACR/ARP Annual Meeting
Inhibition of Choline Kinase Alpha Improves Synovitis and Cartilage Damage in Animal Models of Osteoarthritis
Background/Purpose: Osteoarthritis (OA) is a disease of the whole joint, affecting cartilage, ligaments, menisci, bone and synovial tissue. We previously found that choline kinase alpha…Abstract Number: 1201 • 2018 ACR/ARHP Annual Meeting
Finger Extensor Tendon Involvement Is Frequent in Early Rheumatoid Arthritis
Background/Purpose: Finger extensor involvement (FET) at ultrasound examination (US) was previously described in patients suffering from early psoriatic arthritis. Contradictory results were published in patients…Abstract Number: 2868 • 2018 ACR/ARHP Annual Meeting
Tender Joint Count May Not Reflect Inflammatory Activity in Established Rheumatoid Arthritis Patients; Results from a Longitudinal Study of Tocilizumab
Background/Purpose: Tender joints may be caused by non-inflammatory pathologies but are still included in composite scores like CDAI. The present objective was to explore the…Abstract Number: 2012 • 2017 ACR/ARHP Annual Meeting
First Description of Tenosynovitis Prevalence in a Large Cohort of ACPA-Positive Patients
Background/Purpose: Tenosynovitis has been regarded as a feature of RA, although its true prevalence in early stages has not been firmly established. The aim of…
ACR Meeting Abstracts