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Abstracts tagged "Scleroderma"

  • Abstract Number: 0621 • ACR Convergence 2023

    Scleroderma Renal Crisis: A Large Single-center Experience

    Rushab Shah1, laura ross2, Kathleen Morrisroe3, Wendy Stevens4 and Mandana Nikpour5, 1St Vincent's Hospital Melbourne/ Alfred Hospital, Melbourne, Australia, 2St. Vincent's Hospital Melbourne, Fitzroy, Australia, 3The University of Melbourne at St Vincent’s Hospital Melbourne, Fitzroy, Australia, 4Department of Rheumatology, St Vincent's Hospital Melbourne, Fitzroy, Australia, 5The University of Melbourne at St. Vincent’s Hospital Melbourne, Departments of Medicine and Rheumatology, Melbourne, Australia

    Background/Purpose: Scleroderma renal crisis (SRC) is a life-threatening vascular manifestation of systemic sclerosis (SSc) occurring in up to 5% of SSc patients. This condition continues…
  • Abstract Number: 0661 • ACR Convergence 2023

    Assessment of Systemic Sclerosis-Associated Myocarditis: A Single Center Case Series Study

    Nafsika Gerolymatou1, NIck Koletsos1, Aliki Venetsanopoulou2, Anastasia Giantsouli3, Sophie Mavrogeni4 and PARASKEVI VOULGARI5, 1Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, Ioannina, Greece, 2Medical School of Ioannina, Ioannina, Greece, 3Radiology Department, University Hospital of Ioannina, Ioannina, Greece, 4Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece, 5Rheumatology Clinic, Department of Internal Medicine, University of Ioannina, Ioannina, Greece

    Background/Purpose: Myocardial involvement is a significant contributor to mortality in patients with Systemic Sclerosis (SSc). The objective of this study was to analyze the clinical…
  • Abstract Number: 0961 • ACR Convergence 2023

    Transcriptomic Analysis of Scleroderma Monocytes Identifies Distinct Clinically Relevant Clusters and Novel Genes Associated with Disease Complications

    Mehmed Dinc1, Fatima El Adili2, Justin Lui3, Giovanni Ligresti3, Robert Lafyatis4, Maria Trojanowska3 and Andreea Bujor3, 1Boston University School of Medicine, Boston, MA, 2Boston University School of Medicine, Revere, MA, 3Boston University, Boston, MA, 4University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Systemic sclerosis (SSc) is an autoimmune disease characterized by skin and internal organ fibrosis, vascular abnormalities, and immunological disturbances. Monocytes play a critical role…
  • Abstract Number: 1871 • ACR Convergence 2023

    Utility of Infrared Thermography in Patients with Digital Gangrene

    Nidhish Chandra M, Puneet Kumar, Urmila Dhakad, Shweta Bhardwaj, Sanjay Pruthviraj Buddha, Parag Vijayvergia and Lily Singh, King George Medical University, Lucknow, India

    Background/Purpose: Digital gangrene has been described as a complication of several Autoimmune Inflammatory Rheumatic Diseases(AIIRD). Due to multiple underlying mechanisms causing digital gangrene in AIIRD…
  • Abstract Number: 0622 • ACR Convergence 2023

    The Effectiveness of Breath-holding Test to Predict Pulmonary Function in Systemic Sclerosis Patients Using Machine Learning Model

    Jina Yeo1, Min Hyuk Lim2, Ju Yeon Kim3, Ji In Jung4, Saram Lee2 and Eun Bong Lee3, 1Division of Rheumatology, Department of Internal Medicine, Gachon University Gil Medical Center, Incheon, South Korea, 2Department of Transdisciplinary Medicine, Seoul National University Hospital, Seoul, South Korea, 3Seoul National University Hospital, Seoul, South Korea, 4Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea

    Background/Purpose: Pulmonary involvement is major causes of mortality in patients with systemic sclerosis (SSc). The breath-holding test (BHT), rapid bedside test, is a useful surrogate…
  • Abstract Number: 0665 • ACR Convergence 2023

    A Descriptive Study of Disease Characterisics of SSc Patients with the U2RNP Autoantibody

    Mridula Dilip1, Maureen Laffoon2, Yongseok Park3, Robert Lafyatis4, Thomas Medsger5, Virginia Steen6, Leigh Freno2 and Robyn Domsic4, 1University of Pittsburgh School of Medicine, Pittsburgh, PA, 2University of Pittsburgh Medical Center, Pittsburgh, PA, 3University of Pittsburgh School of Public Health, Pittsburgh, PA, 4University of Pittsburgh, Pittsburgh, PA, 5University of Pittsburgh School of Medicine, Verona, PA, 6Georgetown University School of Medicine, Washington, DC

    Background/Purpose: U2RNP is a spliceosome-associated autoantibody that has in prior case reports presented with scleroderma with myositis (SSc/PM)and SLE overlap. Autoantibodies are growing in prognostic…
  • Abstract Number: 0962 • ACR Convergence 2023

    Topological Proteomic Differences in Fibrotic and Unaffected Skin in Scleroderma

    Irene Choi1, Courtney Yu2, Francesco Boin1, Elizabeth Volkmann3, Stephanie Stanford2 and Nunzio Bottini4, 1Cedars-Sinai Medical Center, Los Angeles, CA, 2University of California San Diego, San Diego, CA, 3University of California Los Angeles, Los Angeles, CA, 4University of California, San Francisco, CA

    Background/Purpose: Scleroderma (SSc) is a chronic autoimmune and rheumatic disease characterized by varying levels of tissue fibrosis in the skin and other internal organs. It…
  • Abstract Number: 1897 • ACR Convergence 2023

    In Pursuit of Excellence: Improving Systemic Sclerosis Quality of Care

    Aos Aboabat1, Samar Aboulenain1, Zareen Ahmad2, Medha Soowamber3 and Sindhu Johnson4, 1University of Toronto, Toronto, ON, Canada, 2Toronto Scleroderma Program, Mount Sinai Hospital, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, 3Toronto Scleroderma Program, Mount Sinai Hospital, Toronto Western Hospital, University of Toronto, Woodbridge, ON, Canada, 4Division of Rheumatology, Department of Medicine, Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western and Mount Sinai Hospitals; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Systemic sclerosis (SSc) is a complex autoimmune disease with significant morbidity and mortality. Quality indicators (QIs) for SSc care, previously published, are essential tools…
  • Abstract Number: 029 • 2023 Pediatric Rheumatology Symposium

    Cardiac Magnetic Resonance Imaging in Children with Systemic Lupus Erythematosus and Scleroderma Spectrum Disorders: A Single Center Experience

    Meredith Rae, Tam Doan and Eyal Muscal, Baylor College of Medicine, Houston, TX

    Background/Purpose: Cardiac disease is a major cause of morbidity and mortality in children with SLE and SSc. Various studies have demonstrated an association between duration…
  • Abstract Number: 086 • 2023 Pediatric Rheumatology Symposium

    Systemic Sclerosis Overlap Syndrome: A Case Series from a Single Large Pediatric Center

    Jessica Nguyen1, Miriah Gillispie-Taylor1, Eyal Muscal1 and Marietta Deguzman2, 1Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Childhood-onset systemic sclerosis (SSc) is a rare but potentially life-threatening autoimmune condition with features including immune, fibrotic, and vascular manifestations affecting the skin and…
  • Abstract Number: 098 • 2023 Pediatric Rheumatology Symposium

    Characterization of Pulmonary Nodules in Juvenile-onset Systemic Sclerosis: A Single Center Case-Series

    Jonathan Li1, Franziska Rosser1, Sameh Tadros1 and Kathryn Torok2, 1UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Given the high prevalence of intestinal lung disease (ILD) in systemic sclerosis (SSc) and the low sensitivity of pulmonary function testing for diagnosing ILD,…
  • Abstract Number: 116 • 2023 Pediatric Rheumatology Symposium

    Clinical Significance of Anti-Scl-70 Antibodies in Pediatric Lupus Patients: A Single Center Cohort

    Dawn Janysek1, Yiressy Pina2, Danielle Guffey3 and Marietta De Guzman1, 1Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 2Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 3Baylor College of Medicine, Houston, TX

    Background/Purpose: Production of autoantibodies is a hallmark of SLE, with ANAs as a required diagnostic feature and anti-dsDNA and anti-Smith antibodies being disease-specific. Anti-Scl-70 antibodies…
  • Abstract Number: 123 • 2023 Pediatric Rheumatology Symposium

    Development of Specific Classification Criteria for Juvenile System Sclerosis Patients: A Scoping Review

    Ioana Dobre1, Suzanne Li2, Natalia Vasquez Canizares3, Barbara Reich4, Xurong Zhao5, Quinn McCormick6 and Marinka Twilt5, 1Alberta Children's Hospital/University of Calgary, Calgary, AB, Canada, 2Hackensack Meridian School of Medicine, Joseph M. Sanzari Children's Hospital, Hackensack, NJ, 3Children's Hospital at Montefiore, New York, NY, 4Hackensack University Medical Center, Hackensack, NJ, 5Alberta Children's Hospital, Calgary, AB, Canada, 6Hackensack Medical Hospital Network, Hackensack, NJ

    Background/Purpose: Juvenile systemic sclerosis (jSSc) is associated with one of the highest morbidity and mortality rate in pediatric rheumatology, yet care recommendations are based upon…
  • Abstract Number: 1058 • ACR Convergence 2022

    Clinical Characteristics and Survival of Combined Pulmonary Arterial Hypertension and Interstitial Lung Disease in Systemic Sclerosis

    Jessica Fairley1, Dylan Hansen2, Laura Ross3, Susanna Proudman4, Jo Sahhar5, Gene-Siew Ngian6, Jenny Walker7, Lauren Host8, Kathleen Morrisroe2, Diane Apostolopoulos9, Nava Ferdowsi2, Michelle Wilson9, Maryam Tabesh2, Wendy Stevens2 and Mandana Nikpour10, 1The University of Melbourne, Melbourne, Australia, 2St Vincent's Hospital Melbourne, Melbourne, Australia, 3The University of Melbourne at St. Vincent's Hospital, Brunswick, Australia, 4University of Adelaide, Medindie, Australia, 5Monash Health, Melbourne, Australia, 6Melbourne Health, Northcote, Australia, 7Royal Adelaide Hospital, Adelaide, Australia, 8Fiona Stanley Hospital, London, United Kingdom, 9Monash University, Melbourne, Australia, 10The University of Melbourne at St. Vincent's Hospital Melbourne, Melbourne, Australia

    Background/Purpose: Pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD) are the leading causes of systemic sclerosis (SSc) associated death. There is increasing interest in…
  • Abstract Number: 1518 • ACR Convergence 2022

    Prevalence, Risk Factors and Treatment Patterns of Digital Ischemic Complications in Systemic Sclerosis: A Single Center Cross-Sectional Study

    Ashima Makol1, Alicia Hinze2, Rachel Giblon1, Yasser Radwan3, Tina Gunderson4, David Liedl1, Kenneth J. Warrington4, Cynthia Crowson5 and Paul Wennberg1, 1Mayo Clinic, Rochester, MN, Rochester, MN, 2Mayo Clinic - Rochester, MN, Rochester, MN, 3Mayo Clinic/ Michigan State University, Lansing, MI, 4Mayo Clinic, Rochester, MN, 5Mayo Clinic, Eyota, MN

    Background/Purpose: Digital ischemic complications (DICs, including digital ulcers, digital pitting/scars, gangrene and/or amputation) can significantly impact hand function, disability and overall prognosis in SSc. We…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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