ACR Meeting Abstracts

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Abstracts tagged "Scleroderma"

  • Abstract Number: 0174 • ACR Convergence 2024

    A Nationwide Analysis of Gender and Racial Disparities in Patients with Systemic Sclerosis and Acute Coronary Syndrome

    Omair Khan1, Kundan Jana2, Azka Naeem2, Syed Mujtaba Baqir2, Marlon Rivera Boadla2, Muhammad Hashim khan2 and Vijay Shetty2, 1Maimonides Medical Center, Council Bluffs, IA, 2Maimonides Medical Center, Brooklyn, NY

    Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune condition characterized by widespread skin fibrosis and/or end-organ damage. Previous studies have reported variable outcomes of the disease…
  • Abstract Number: 0705 • ACR Convergence 2024

    Identification of Risk Factors for Incident Cardiomyopathy in Patients with Systemic Sclerosis

    Ji Soo Kim1, Rachel Wallwork1, Carrie Richardson2, Adrianne Woods3, Monica Mukherjee4, Steven Hsu4, Julie Paik1, Christopher Mecoli1, Laura Hummers5, Fredrick Wigley6, Scott Zeger1 and Ami Shah7, 1Johns Hopkins University, Baltimore, MD, 2Northwestern University, Chicago, 3Johns Hopkins University Division of Rheumatology, Baltimore, MD, 4Johns Hopkins University Division of Cardiology, Baltimore, MD, 5Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Ellicott City, MD, 6Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Baltimore, MD, 7Division of Rheumatology, Johns Hopkins University, Ellicott City, MD

    Background/Purpose: Cardiac involvement in systemic sclerosis (SSc) is one of the leading causes of scleroderma-associated death. There are limited data examining risk factors for incident…
  • Abstract Number: 1236 • ACR Convergence 2024

    A Novel Role for Artificial Intelligence in Detecting Distinctive Scleroderma Facial Features

    yossra suliman1 and daniel Furst2, 1Assiut university hospital, assiut, Egypt, 2Pacific Arthritis Center, Inglewood

    Background/Purpose: Scleroderma (SSc) is a rare autoimmune fibrosing disease with high rates of morbidity and mortality. Scleroderma is usually diagnosed by rheumatologists and/or dermatologists. However,…
  • Abstract Number: 1689 • ACR Convergence 2024

    Pulmonary Function Test Reference Equations May Drive Inequitable Classification of Restrictive Lung Disease Severity in Systemic Sclerosis

    Kamini Kuchinad1, Rachel Wallwork2, Matthew Lammi3, Christopher Mecoli1, Julie Paik1, Fredrick Wigley4, Robert Wise1, Laura Hummers5, Ami Shah6 and Ji Soo Kim1, 1Johns Hopkins University, Baltimore, MD, 2Johns Hopkins University, Towson, MD, 3Johns Hopkins University Division of Pulmonary and Critical Care Medicine, Baltimore, MD, 4Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Baltimore, MD, 5Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Ellicott City, MD, 6Division of Rheumatology, Johns Hopkins University, Ellicott City, MD

    Background/Purpose: Black individuals with systemic sclerosis (SSc) have an increased frequency and severity of interstitial lung disease (ILD) as compared to their White counterparts. Pulmonary…
  • Abstract Number: 1867 • ACR Convergence 2024

    RNA Polymerase III Specific CD8+ T Cells at the Interface Between Scleroderma and Cancer

    Eleni Tiniakou1, Mekha Thomas2, Ami Shah3, Fredrick Wigley4, Livia Casciola-Rosen2, Kellie Smith2, Antony Rosen2 and Erika Darrah2, 1Johns Hopkins University, Lutherville Timonium, MD, 2Johns Hopkins University, Baltimore, MD, 3Division of Rheumatology, Johns Hopkins University, Ellicott City, MD, 4Johns Hopkins University, Division of Rheumatology, Baltimore, MD, Baltimore, MD

    Background/Purpose: Increasing evidence suggests an immunologic link between cancer and autoimmunity. Systemic sclerosis (SSc), offers a unique opportunity to study the evolution of naturally occurring…
  • Abstract Number: 2465 • ACR Convergence 2024

    Subclinical Loss of Lung Volumes in Very Early SSc: Evidence from Two Independent Cohorts in EUSTAR

    Vishal Kakkar1, Stefano Di Donato2, Silvia Bellando-Randone3, Riccardo Bixio4, Marco Matucci-Cerinic5, Yannick Allanore6 and Francesco Del Galdo1, 1University of Leeds, Leeds, United Kingdom, 2Leeds Institute of Rheumatic and Musculoskeletal Medicine, Chapel Allerton Hospital, Leeds, UK, Leeds, United Kingdom, 3University of Florence, Florence, Florence, Italy, 4University of Verona, Verona, Verona, Italy, 5University San Raffaele Milano, Milano, Milan, Italy, 6Université Paris Cité, Paris, France

    Background/Purpose: Interstitial lung disease (ILD) remains as the major driver of mortality in systemic sclerosis (SSc). The literature indicates that at the time of diagnosis…
  • Abstract Number: 0309 • ACR Convergence 2024

    Characteristics and Factors Associated with Treatment Response Among Patients with Eosinophilic Fasciitis: A Systematic Review and Meta-analysis

    Omar Hamdan1, Roa'a Alshajrawi1, Qais Mussa1, Yazeed Alajlouni1, Yazan Dabbah1, Rawan Fratekh1, Yousef Al-Mabrouk2, Shatha Al-Mabrok2 and Ahmad A. Toubasi1, 1University of Jordan, Amman, Jordan, 2Mansoura University, Al Mansoura, Egypt

    Background/Purpose: To date, data on the clinical features, diagnosis and the treatment of Eosinophilic Fasciitis (EF) patients are mostly derived from individual case reports, with…
  • Abstract Number: 0706 • ACR Convergence 2024

    Single Center Prospective Cohort of Systemic Sclerosis Patients Who Are At-Risk for Pulmonary Hypertension

    Carleigh Zahn1, Scott Visovatti2, Rosemary Gedert1, Suiyuan Huang1, Victor Moles1, Amber Young1, Vallerie McLaughlin1 and Dinesh Khanna1, 1University of Michigan, Ann Arbor, MI, 2The Ohio State University, Columbus

    Background/Purpose: Pulmonary hypertension (PH) is a leading cause of mortality in systemic sclerosis (SSc). We launched an IRB approved prospective study (NOVEL) in 2013 at…
  • Abstract Number: 1244 • ACR Convergence 2024

    Creation of a New Patient-reported Outcome for a Combined Response Index for Limited Cutaneous SSc Using the FDA Guidance on Patient Reported Outcome Measures: The CRISTAL PRO

    Alain Lescoat1, Yen Chen2, Rosemary Gedert2, Neda Kortam2, Nadia Vann2, David Cella3, Sara Shaunfield4, Susan Murphy5 and Dinesh Khanna2, 1CHU Rennes - University Rennes 1, Rennes, France, 2University of Michigan, Ann Arbor, MI, 3Northwestern University, Chicago, IL, 4Northwestern University, Chicago, 5University of Michigan, Plymouth, MI

    Background/Purpose: Limited cutaneous systemic sclerosis (lcSSc) is the most frequent subset of scleroderma, yet there is a paucity of outcome measures to assess symptoms that…
  • Abstract Number: 1692 • ACR Convergence 2024

    Single Cell RNA-seq Identifies Circulating Double-negative-2 B-cell Population Associated with Progressive Scleroderma Interstitial Lung Disease

    Trinitee Oliver1, Kim Taylor2, Ye Cao3, Takanori Sasaki4, Deepak Rao5, Nunzio Bottini6, Francesco Boin6 and Richard Ainsworth6, 1Cedars-Sinai Medical Center, Hawthorne, CA, 2University of California, San Francisco, CA, 3Brigham and Women's Hospital and Harvard Medical School, Boston, Boston, MA, 4Brigham and Women's Hospital and Harvard Medical School, Brookline, MA, 5Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 6Cedars-Sinai Medical Center, Los Angeles, CA

    Background/Purpose: B-cell subsets display aberrant function in systemic sclerosis (SSc) pathogenesis and infiltrate the lungs of SSc patients with interstitial lung disease (ILD). B-cells relevance…
  • Abstract Number: 1914 • ACR Convergence 2024

    Racial and Ethnic Differences in the Prevalence of Disease Features in Systemic Sclerosis

    Harry Hurley1, Davina Chen2, Xianhong Xie3, Manpreet Parmar4 and Bibi Ayesha5, 1Albert Einstein College of Medicine, Maplewood, NJ, 2Montefiore Medical Center, New Rochelle, NY, 3Albert Einstein College of Medicine, Bronx, NY, 4Montefiore, Bronx, NY, 5Montefiore Medical Center, Metuchen, NJ

    Background/Purpose: Systemic sclerosis (SSc) is a chronic, systemic autoimmune disease with a higher prevalence among women and racial/ethnic minority groups in the US. Despite the…
  • Abstract Number: 2468 • ACR Convergence 2024

    Audio-Guided Imagery Positively Impacted Patients with Raynaud’s Phenomenon Associated Connective Tissue Disease

    Cristina Padilla1, Veena Katikineni2, Yongseok Park1, Leigh Freno3, Maureen Laffoon4 and Robyn Domsic5, 1University of Pittsburgh, Pittsburgh, PA, 2Providence, Victorville, CA, 3University of Pittsburgh Medical Center, Pittsburgh, PA, 4UPMC, Pittsburgh, PA, 5Division of Rheumatology and Clinical Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA

    Background/Purpose: Raynaud’s phenomenon (RP) is characterized as episodic color changes of the digits occurring with exposure to cold environments, sudden temperature decreases, and emotional stress. …
  • Abstract Number: 0361 • ACR Convergence 2024

    Maternal and Fetal Outcomes in Those with Autoimmune Connective Tissue Disease

    Nada Alrifai1, Anushree Puttur2, Laith Alhuneafat3, Fares Ghanem4, yadhu Dhital2, Ahmad Jabri5 and David Feinstein6, 1Cooper University Hospital, Cherry Hill, NJ, 2Allegheny Health Network, Pittsburgh, PA, 3University of Minnesota, Minneapolis, MN, 4Southern Illinois University, Springfield, IL, 5Henry Ford, Detroit, MI, 6Cooper University, Camden, NJ

    Background/Purpose: Autoimmune connective tissue diseases (CTD) predominantly affect women during their reproductive years. CTDs such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and systemic…
  • Abstract Number: 0710 • ACR Convergence 2024

    High S100A4 Levels Associate with Inflammation and Vasculopathy in Systemic Sclerosis

    Adela-Cristina Sarbu1, Håvard Fretheim2, Ladislav Šenolt3, Henriette Didriksen4, Cosimo Bruni5, Marco Sprecher6, Thor Ueland7, Jonas Hallén8, Rizwan Hussain9, Jörg Klingelhöfer10, Michal Tomcik11, Yannick Allanore12, Oliver Distler13 and Anna-Maria Hoffmann-Vold2, 1University Hospital Zurich, University of Zurich, Department of Rheumatology, Bern, Switzerland, 2Oslo University Hospital, Oslo, Norway, 3Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 4Oslo University Hospital, Moss, Norway, 5University of Zurich, Zurich, Switzerland, 6Universitätsspital Zürich (University Hospital Zurich), Zürich, Switzerland, 7Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, 8Arxx Therapeutics, Oslo, Norway, Oslo, Norway, 9Agiana Therapeutics, Oslo, Norway, Oslo, Norway, 10Calluna Pharma, Oslo, Norway, Oslo, Norway, 11Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 12Université Paris Cité, Paris, France, 13Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Zurich, Switzerland

    Background/Purpose: S100A4, a member of the S100 protein family, is implicated in various cellular processes. In systemic sclerosis (SSc), S100A4 is believed to contribute to…
  • Abstract Number: 1559 • ACR Convergence 2024

    Vectorcardiography for Identification of Systemic Sclerosis Patients at Risk for Pulmonary Hypertension

    S. Ahmed1, Eva Hoekstra2, Katie van der Wouden2, Sum-Che Man2, Kees Swenne2, Madelon Vonk3, Anna-Maria Hoffmann-Vold4, Cosimo Bruni5, Udo Mulder6, Thomas Huizinga7, H.W. Vliegen2 and Jeska de Vries-Bouwstra2, 1Leiden University Medical Centre, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands, 3Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, 4Oslo University Hospital, Oslo, Norway, 5University of Zurich, Zurich, Switzerland, 6Universitair Medisch Centrum Groningen, Groningen, Netherlands, 7Department of Rheumatology, Leiden University, Leiden, Netherlands

    Background/Purpose: Pulmonary hypertension (PH) in SSc causes significant disease burden and requires invasive diagnosis with right heart catheterization (RHC). Comprehensive work-up is needed to identify…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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