Abstracts tagged "Rheumatoid arthritis (RA)"

Abstract Number: 1361 • 2019 ACR/ARP Annual Meeting
Utility of Rheumatoid Arthritis Impact of Disease (RAID) in Routine Care; Identification of Patients Achieving DAS28 Remission or Low Disease Activity, and Burden of Unmet Patient Reported Outcomes
Jatin Mistry ¹, Margaret Sibley ², Catherine Smith ³, Malama Sumbwanyambe ² and Patrick Kiely², ¹St George's University of London, London, United Kingdom, ²St George's University Hospitals NHS Trust, London, United Kingdom, ³St Georges University Hospitals NHS Foundation Trust, London, United Kingdom
Background/Purpose: ACR/EULAR guidelines recommend remission or low DAS28 as the treat to target goal for patients with rheumatoid arthritis (RA). Alternative patient reported outcomes include…
Abstract Number: 1387 • 2019 ACR/ARP Annual Meeting
Low Probability of Clinical Worsening Following Switching Biologic DMARD in Patients with RA and Partial Response to Adalimumab
Jeffrey Curtis¹, Daniel Aletaha ², Gerd Burmester ³, Kerri Ford ⁴, Hubert van Hoogstraten ⁵, Henry Leher ⁶, Karthinathan Thangavelu ⁷ and Vivian Bykerk ⁸, ¹University of Alabama at Birmingham, Birmingham, AL, ²Medical University of Vienna, Vienna, Austria, ³Charité—University Medicine Berlin, Berlin, Germany, ⁴Sanofi Genzyme, Bridgewater, NJ, ⁵Sanofi, Bridgewater, NJ, ⁶Regeneron Pharmaceuticals, Inc, Tarrytown, NY, ⁷Sanofi Genzyme, Boston, MA, ⁸Hospital for Special Surgery, New York City, NY
Background/Purpose: Guidelines recommend adjusting therapy in patients with RA who fail to reach low disease activity or remission. Partial responders to a TNF inhibitor may…
Abstract Number: 1421 • 2019 ACR/ARP Annual Meeting
Effect of Tocilizumab on HDL and LDL Characteristics in Patients with Rheumatoid Arthritis: Preliminary Results
Florencia Pierini¹, Ignacio Gandino ¹, Eliana Botta ², Fernando Brites ², Tomas Meroño ², Osvaldo Luis Cerda ³, Gustavo Citera ⁴, Javier Rosa ⁵, Patricia Sorroche ⁶, Laura Boero ², Maximiliano Martin ², Soledad saez ⁶, Walter Tetzlaff ² and Enrique Soriano ⁷, ¹Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina., Capital Federal, Argentina, ²Universidad de Buenos Aires, Buenos Aires, Argentina, ³Instituto de Rehabilitación Psicofísica, Ciudad Autonoma de Buenos Aires, Ciudad Autonoma de Buenos Aires, Argentina, ⁴Instituto de Rehabilitación Psicofísica, Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina, ⁵Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina, Buenos Aires, Argentina, ⁶Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, ⁷Rheumatology Section, Internal Medicine Service, Hospital Italiano de Buenos Aires, Argentina., Buenos Aires, Buenos Aires, Argentina
Background/Purpose: In patients with Rheumatoid Arthritis (RA), qualitative alterations of low and high density lipoproteins (LDL and HDL, respectively) might partially explain their increased cardiovascular…
Abstract Number: 1858 • 2019 ACR/ARP Annual Meeting
Beta-2-Glycoprotein-I IgA Antibodies Predict Coronary Plaque Burden, Progression and Moderate the Effect of Inflammation on Atherosclerosis in Rheumatoid Arthritis
George Karpouzas¹, Sarah Ormseth ¹, Elizabeth Hernandez ¹, Viet Bui ¹ and Matthew Budoff ¹, ¹Harbor-UCLA Medical Center and Los Angeles Biomedical Institute, Torrance, CA
Background/Purpose: Beta-2-glycoprotein-I(b2GPI), an apolipoprotein abundant in plasma, is readily expressed in human atherosclerotic plaque. Anti-b2GPI-IgA antibodies (Ab) have been previously reported in both rheumatoid arthritis…
Abstract Number: 1940 • 2019 ACR/ARP Annual Meeting
Investigating the Post-Partum Flare in Rheumatoid Arthritis Using Transcriptome Analysis
Matthew Wright¹, Dana Goin ², Mette Smed ³, Lior Pachter ⁴, J. Lee Nelson ⁵, Nicholas Jewell ⁶, Jørn Olsen ⁷, Merete Lund Hetland ⁸, Vibeke Zoffmann ⁹ and Damini Jawaheer ¹⁰, ¹UCSF Benioff Children's Hopsital Oakland, Oakland, ²UCSF Benioff Children's Hospital Oakland, Oakland, ³Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, ⁴Caltech, Pasadena, ⁵Fred Hutchinson Cancer Research Center, Seattle, ⁶University of California Berkeley, Berkeley, ⁷Aarhus University Hospital, Aarhus, Denmark, ⁸DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ⁹Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, ¹⁰UCSF Benioff Children's Hospital Oakland, Oakland, CA
Background/Purpose: Women with Rheumatoid arthritis (RA) tend to have a predictable flare of disease activity in the months after childbirth. The mechanism(s) underlying this post-partum…
Abstract Number: 2094 • 2019 ACR/ARP Annual Meeting
Evaluation of Influenza and Pneumococcal Vaccination Rate in Patients with Rheumatoid Arthritis and Spondyloarthritis, and the Attitudes of Rheumatologists About Vaccination
İdil Kurut Aysin ¹, Murat Aysin ², Dilek Solmaz ³, Nazmiye Baş Tomas ⁴, Filiz Koç ⁴, Elif Durak Ediboğlu ⁴, Gokhan Kabadayi ⁵, Onay Gercik ³, Sercan Gücenmez ⁴ and Servet Akar⁶, ¹Izmir Katip Celebi University Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, ²University of Izmir Katip Celebi Faculty of Medicine, Public Health, İzmir, Turkey, ³Izmir Katip Celebi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, ⁴University of Izmir Katip Celebi Faculty of Medicine, Rheumatology, İzmir, Turkey, ⁵Izmir Katip Celebi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, ⁶Izmir Katip Celebi University, Faculty of Medicine, Division of Rheumatology, İzmir, Turkey
Background/Purpose: Patients with inflammatory arthritis have increased risk of infections which may lead to morbidity and mortality. Some of those infections could be prevented by…
Abstract Number: 2259 • 2019 ACR/ARP Annual Meeting
Physical Challenges in RA: A Qualitative Study of an Online Patient Support Group
Jude des Bordes ¹, Jessica Foreman ¹, Maria Lopez-Olivo¹, Susan K Peterson ¹, Tiffany Westrich-Robertson ², Catherine Hofstetter ³, Anne Lyddiatt ⁴, Amye Leong ⁵ and Maria E. Suárez-Almazor ⁶, ¹The University of Texas, MD Anderson Cancer Center, Houston, TX, ²International Foundation for Autoimmune and Autoinflammatory Arthritis, Saint Louis, MO, ³Patient advocate, Toronto, ON, Canada, ⁴Musculoskeletal Group, Cochrane Collaboration, Toronto, ON, Canada, ⁵7. Healthy Motivation and the Global Alliance for Musculoskeletal Health of the Bone and Joint Decade, Santa Barbara, CA, ⁶Department of Rheumatology/Clinical Immunology, The University of Texas MD Anderson Cancer Center, Houston, TX , USA., Houston, TX
Background/Purpose: Patients with rheumatoid arthritis (RA) face a number of challenges which adversely affect their quality of life. The objective was to qualitatively evaluate content…
Abstract Number: 2315 • 2019 ACR/ARP Annual Meeting
Association of Rheumatic Autoimmune Disease, Including Rheumatoid Arthritis, with Post-Traumatic Stress Disorder but Not Traumatic Brain Injury in Veterans
Biji Kurien ¹, Calin Prodan ² and Robert Scofield¹, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Department of Neurology, University of Oklahoma Health Sciences Center, Oklahoma City, OK
Background/Purpose: Autoimmune diseases, including rheumatoid arthritis (RA) and systemic lupus erythematosus, are 2- to 3-fold more common among those with post-traumatic stress disorder (PTSD) than…
Abstract Number: 2333 • 2019 ACR/ARP Annual Meeting
Risk of Incident Myocardial Infarction Among Disabled Patients with Rheumatoid Arthritis Who Were Beneficiaries of the Social Security Disability Insurance
Iris Navarro-Millan¹, Mangala Rajan ¹, Geyanne Lui ¹, Lisa Kern ¹, Laura Pinheiro ¹, Sebastian E. Sattui ², Lisa Mandl ³, Fenglong Xie ⁴, Jeffrey Curtis ⁵ and Monika Safford ¹, ¹Weill Cornell Medicine, New York, ²Hospital for Special Surgery, New York, ³Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, New York, NY, ⁴University of Alabama at Birmingham, Birmingham, ⁵University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Patients with RA have high risk for myocardial infarction (MI). A meta-analysis showed that the age and sex adjusted pooled relative risk of MI…
Abstract Number: 2358 • 2019 ACR/ARP Annual Meeting
Short-term Risk of Major Adverse Cardiovascular Events or Venous Thrombo-embolic Events in Patients with Rheumatoid Arthritis Initiating a Janus Kinase Inhibitor: A Meta-analysis of Randomised Controlled Trials
Margaux MALAURIE¹, Arnaud Constantin ², Yannick Degboé ¹, Adeline Ruyssen-Witrand ³ and Thomas Barnetche ⁴, ¹CHU TOULOUSE, TOULOUSE, France, ²CHU TOUOUSE, TOULOUSE, France, ³Rheumatology Unit, Toulouse university Hospital, UMR 1027, Inserm, Université Paul Sabatier Toulouse III, Toulouse, France, ⁴FHU ACRONIM, Department of Rheumatology, Centre Hospitalier Universitaire, Bordeaux, France, Bordeaux, France
Background/Purpose: The objective was to investigate the short-term risk of major adverse cardiovascular events (MACEs) or venous thromboembolic events (VTEs) in patients with rheumatoid arhthritis…
Abstract Number: 2384 • 2019 ACR/ARP Annual Meeting
Yoga Improves Fatigue and Mental Health in Rheumatoid Arthritis: Preliminary Results of a Randomized Controlled Trial
Silva Pukšić¹, Joško Mitrović ², Melanie-Ivana Čulo ², Marcela Živković ³, Biserka Orehovec ⁴, Dubravka Bobek ⁵, Marko Lucijanić ⁶ and Jadranka Morović-Vergles ⁷, ¹Department of Clinical Immunology, Rheumatology and Allergology, University Hospital Dubrava, Zagreb, Croatia, Zagreb, Croatia, ²Department of Clinical Immunology, Rheumatology and Allergology, University Hospital Dubrava, Zagreb, Croatia, ³Department of Laboratory Diagnostics, University Hospital Dubrava, Zagreb, Croatia, Zagreb, Croatia, ⁴Department of Laboratory Diagnostics, University Hospital Dubrava, Zagreb, Croatia, ⁵Department of Physical Medicine and Rehabilitation with Rheumatology, University Hospital Dubrava, Zagreb, Croatia, Zagreb, Croatia, ⁶Department of Hematology, University Hospital Dubrava, Zagreb, Croatia, Zagreb, Croatia, ⁷Department of Clinical Immunology, Rheumatology and Allergology, University Hospital Dubrava, School of Medicine,Zagreb, Croatia, Zagreb, Croatia
Background/Purpose: Rheumatoid arthritis (RA) patients perceive reduced health-related quality of life (HRQOL) through functional disability, pain, increased fatigue and impaired psychological functioning. Previous trials demonstrated…
Abstract Number: 2716 • 2019 ACR/ARP Annual Meeting
Long Term Outcomes of Childhood Onset Rheumatoid Arthritis
Rebecca Overbury¹, Aimee Hersh ², CJ Inman ², Sara Stern ², Karen James ² and John Bohnsack ³, ¹Assisstant Professor, University of Utah, Salt Lake City, UT, ²University of Utah, Salt Lake City, UT, ³University of Utah School of Medicine, Salt Lake City, UT
Background/Purpose: Childhood onset rheumatoid arthritis (CORA) describes patients with juvenile idiopathic arthritis (JIA) who are rheumatoid factor (RF) or anti-cyclic citrullinated antibody (ACPA) positive. Phenotypically,…
Abstract Number: 2852 • 2019 ACR/ARP Annual Meeting
Shared and Differing Risk Factors for PsA, Psoriasis, AS, and RA: A Series of Case-control Studies
Alexis Ogdie¹, Xingmei Wang ¹, Thorvardur J Love ², Telma Thrastardottir ³, Maureen Dubreuil ⁴ and Joel Gelfand ⁵, ¹Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, ²Faculty of Medicine, University of Iceland, Reykjavik, Iceland, ³University of Iceland, Reykjavik, Iceland, ⁴Boston University School of Medicine, Boston, ⁵University of Pennsylvania, Philadelphia, PA
Background/Purpose: While a handful of clinical risk factors for the development of inflammatory diseases have been identified, to date, no studies have compared risk factors…
Abstract Number: 7 • 2019 ACR/ARP Annual Meeting
Citrullination of Interleukin 6 Augments Its Pro-inflammatory Capacity and Signaling Potency Through Interleukin-6 Receptor in Rheumatoid Arthritis
Chenyang Lu ¹, Ray Ohara ², Phillip Campbell ¹, Yuxuan Du ³, Alexander Stinson ², Jonatan Hervoso ³, Ellen Cealey ³, David Fox ⁴ and M Amin⁵, ¹the University of Michigan, Ann Arbor, MI, ²Washington University, St. Louis, MO, ³the University of Michigan, Ann Arbor, ⁴University of Michigan, Ann Arbor, ⁵University of Michigan, Ann Arbor, MI
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disorder featured by synovial hyperplasia, inflammatory cell infiltration and presence of anti-citrullinated peptide antibodies (ACPAs) in sera.…
Abstract Number: 58 • 2019 ACR/ARP Annual Meeting
In Rheumatoid Arthritis (RA) Decreases in Conventional Dendritic Cell Lineages Are Associated with Adverse Measures of Myocardial Function and Expansions of Anomalous HLA-DR+ Myeloid Subsets
Christian Geier¹, Jon Giles ², Gilad Gibor ³, Joan Bathon ² and Robert Winchester ³, ¹Columbia University, New York, NY, ²Division of Rheumatology, Columbia University, New York, NY, ³Columbia University, New York
Background/Purpose: Dendritic cells (DC) are specialized antigen-presenting cells (APC) that have a central role in the initiation of immune responses. However, prior studies showed numeric decreases…

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