Abstracts tagged "Rheumatoid arthritis (RA)"

Abstract Number: 2061 • 2019 ACR/ARP Annual Meeting
Association of Periodontitis with Rheumatological Disorders: NHANES III Analysis
Vivekanand Tiwari¹, Lawrence Brent ¹, Jasim Albandar ², Chinhua Hsiao ² and Shikha Shah ³, ¹Temple University, Philadelphia, PA, ²Kornberg School of Dentistry, Temple University, Philadelphia, PA, ³Levy Center for Oral Health Research, Philadelphia, PA
Background/Purpose: The association between periodontal diseases, smoking, and some systemic diseases such as diabetes mellitusis is well established. Periodontitis and rheumatological disorders share common immunological features and…
Abstract Number: 2253 • 2019 ACR/ARP Annual Meeting
Comparing Patient and Provider Perspectives on Long Term Biologic Use and Tapering in Stable, Well-Controlled Rheumatoid Arthritis
Patrick Webster¹, Nicole Wilson ², Christina Payne ¹, Kelly Shields ³ and Tarun Sharma ¹, ¹Allegheny Health Network, Pittsburgh, PA, ²Medicine Institute Research, Bioinformatics, Pittsburgh, PA, ³Highmark Data Science, Pittsburgh
Background/Purpose: The 2015 American College of Rheumatology (ACR) and 2013 European League Against Rheumatology (EULAR) guidelines for management of rheumatoid arthritis (RA) conditionally recommend consideration…
Abstract Number: 2313 • 2019 ACR/ARP Annual Meeting
Patients with Rheumatoid Arthritis Have a Higher Risk of Bipolar Disorder: A Systematic Review and Meta-analysis
Patompong Ungprasert¹, Nipith Charoenngam ² and Ben Ponvilawan ², ¹Cleveland Clinic, Cleveland, OH, Bangkok, Thailand, ²Mahidol University, Bangkok, Thailand
Background/Purpose: Patients with chronic autoimmune diseases may have a higher risk of psychiatric illness as a result of chronic neuro-inflammation and immune dysregulation. The current…
Abstract Number: 2331 • 2019 ACR/ARP Annual Meeting
Association of Rheumatoid Arthritis-related Autoantibodies with Pulmonary Function Test Abnormalities in a Prospective Rheumatoid Arthritis Registry
Sicong Huang¹, Xintong He ¹, Tracy J. Doyle ², Alessandra Zaccardelli ¹, Allison Marshall ¹, H. Maura Friedlander ³, Rachel Blaustein ³, Elisabeth Smith ³, Christine Iannaccone ¹, Taysir Mahmoud ³, Michael Weinblatt ¹, Paul Dellaripa ¹, Nancy Shadick ¹ and Jeffrey Sparks ¹, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Harvard Medical School, Boston, ³Brigham and Women's Hospital, Boston
Background/Purpose: Pulmonary involvement in rheumatoid arthritis (RA), such as bronchiectasis, bronchiolitis, pleuritis, or interstitial lung disease (ILD), is associated with high morbidity and mortality. Pulmonary…
Abstract Number: 2355 • 2019 ACR/ARP Annual Meeting
Antirheumatic Therapy Is Associated with Reduced Complement Activation in Rheumatoid Arthritis
Thao Nguyen¹, Ingrid Hokstad ², Gia Deyab ³, Tom Eirik Mollnes ⁴, Stefan Agewall ⁴, Morten Fagerland ⁴, Gro Eilertsen ⁵, Mark Feinberg ⁶, Knut Mikkelsen ², Øystein Førre ⁴ and Ivana Hollan ⁷, ¹Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, ²Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Oppland, Norway, ³Innlandet Hospital Trust, Bærum, Akershus, Norway, ⁴Oslo University Hospital, Oslo, Norway, ⁵The Artic University of Norway, Tromsø, Norway, ⁶Harvard Medical School and Brigham and Women´s Hospital, Boston, Boston, MA, ⁷Lillehammer Hospital for Rheumatic Diseases and Brigham and Women’s Hospital, Boston, Lillehammer, Oppland, Norway
Background/Purpose: Inflammation and immune dysregulation appear to significantly contribute to increased risk of cardiovascular disease (CVD) in rheumatoid arthritis (RA). The complement system is a…
Abstract Number: 2378 • 2019 ACR/ARP Annual Meeting
Comparative Analysis of Clinical, Laboratory and Therapeutic Strategies Among Blacks with Rhupus, SLE and RA
Naureen Kabani¹, Joshy Pathiparampil ², Madina Abduraimova ², Latoya Freeman-Beman ², Sima Terebelo ¹, Abida Hasan ¹, Christon Grant ¹, James Salgado ¹, Manjeet Bhamra ¹, Tracian James-Goulbourne ¹, Khabbab Amin ¹, Yamen Homsi ³ and Isabel McFarlane ², ¹SUNY Downstate Medical Center, Brooklyn, ²SUNY Downstate Medical Center, Brooklyn, NY, ³NYU Langone Medical Center, Brooklyn, NY
Background/Purpose: Rhupus is the overlap of SLE and RA. While a few studies have been conducted among Rhupus patients, no studies have focused on Black…
Abstract Number: 2415 • 2019 ACR/ARP Annual Meeting
Evaluation of Pharmacokinetics and Immunogenicity Following Subcutaneous Administration of Abatacept in Primary Sjogren ’s Syndrome (pSS) and RA Patients
Yash Gandhi¹, Mehmooda Shaikh ², Blisse Vakkalagadda ¹, Grigor Abelian ¹, Neelanjana Ray ¹, Robert Wong ¹ and Bindu Murthy ¹, ¹Bristol-Myers Squibb, Princeton, ²Bristol-Myers Squibb, Princeton, NJ
Background/Purpose: Abatacept (ABA) has proven efficacy in autoimmune diseases and is being evaluated in pSS. The purpose of this investigation was to evaluate the pharmacokinetics…
Abstract Number: 2849 • 2019 ACR/ARP Annual Meeting
Radiographic Progression During a 10-Year Follow-Up : Results from the French Cohort ESPOIR
Joanna Kedra¹, David Hajage ², Alexandre Lafourcade ², Bernard Combe ³, Maxime Dougados ⁴ and Bruno Fautrel ⁵, ¹Sorbonne Université, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), UMR S1136, Paris France, Paris, France, ²Biostatistics, Public Health and Medical Information department, Pitié-Salpêtrière Hospital, AP-HP, Paris, France, Paris, France, ³CHU Montpellier, Montpellier University, Montpellier, France, ⁴Cochin Hospital, Paris, France, ⁵Pitié-Salpêtrière Hospital, Department of Rheumatology, AP-HP, Sorbonne University, UPMC university, Paris, Ile-de-France, France
Background/Purpose: In early arthritis, identification of patients at risk of developing joint damage is an important issue. In rheumatoid arthritis (RA), the rate of progression…
Abstract Number: 4 • 2019 ACR/ARP Annual Meeting
AMP Deaminase 2 Surface Expression Counteracting CD73-Driven Generation of Anti-Inflammatory Extracellular Adenosine
Lisa Ehlers¹, Aditi Kuppe ¹, Cindy Strehl ¹, Marieluise Kirchner ², Frank Buttgereit ³ and Timo Gaber ¹, ¹Charite University Hospital Berlin, Berlin, Germany, ²Max Delbrück Center for Molecular Medicine, BIH Core Facility Proteomics, Berlin, Germany, ³Charité-Universitätsmedizin Berlin, Berlin, Germany
Background/Purpose: Adenosine and its nucleotides represent crucial immunomodulators in the extracellular environment. ATP and ADP are released from stressed cells in states of inflammation, whereas…
Abstract Number: 57 • 2019 ACR/ARP Annual Meeting
Endothelial Progenitor Cells in the Pathophysiology of Interstitial Lung Disease Associated with Rheumatoid Arthritis
Veronica Pulito-Cueto¹, Sara Remuzgo-Martínez ¹, Fernanda Genre ¹, Leticia Lera-Gomez ¹, Veronica Mijares ¹, Pilar Alonso Lecue ², Victor Manuel Mora Cuesta ², David Iturbe ³, Sonia M. Fernández Rozas ², Ricardo Blanco ⁴, Alfonso Corrales ¹, Jose Manuel Cifrian Martínez ², Raquel López-Mejías ¹ and Miguel A Gonzalez-Gay ⁴, ¹Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain, Santander, Spain, ²Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL; and Pneumology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain, Santander, Spain, ³Epidemiology, Genetics and Atherosclerosis Research Group on Systemic Inflammatory Diseases, IDIVAL, Santander, Spain; and Pneumology Department, Hospital Universitario Marqués de Valdecilla, Santander, Spain, Santander, Spain, ⁴Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain
Background/Purpose: Interstitial lung disease (ILD) is one of the most significant comorbidities that contributes to the increased mortality observed in patients with rheumatoid arthritis (RA)…
Abstract Number: 186 • 2019 ACR/ARP Annual Meeting
Asthma, Chronic Obstructive Pulmonary Disease, and Subsequent Risk for Incident Rheumatoid Arthritis Among Women: A Prospective Cohort Study
Julia Ford¹, Xinyi Liu ¹, Su H. Chu ², Bing Lu ¹, Michael Cho ¹, Edwin Silverman ¹, Karen Costenbader ¹, Carlos Camargo ³ and Jeffrey Sparks ¹, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³Massachusetts General Hospital, Boston, MA
Background/Purpose: While RA patients are known to have excess respiratory morbidity and mortality, less is known about the role of chronic respiratory diseases in the…
Abstract Number: 276 • 2019 ACR/ARP Annual Meeting
Effectiveness of Screening by Nurse with Predetermined Questionnaire on Infections Before Administration of Intravenous Biologics in Patients with Rheumatoid Arthritis
Sayaka Furukawa¹, Sho Fukui ¹, Sakura Tamaki ², Tomoko Nakasone ³ and Masato Okada ⁴, ¹St.Luke's International Hospital, Chuo-ku, Tokyo, Japan, ²St. Luke's International Hospital, Chuo-ku, Japan, ³St. Luke's International Hospital, Chuo-ku, Tokyo, Japan, ⁴St. Luke's International Hospital, Tokyo, Japan
Background/Purpose: Biologics are widely used as treatment for rheumatoid arthritis (RA), and pre-administration screening of active infection is imperative for the safety use. There is…
Abstract Number: 446 • 2019 ACR/ARP Annual Meeting
High MDHAQ/RAPID3 (Multidimensional Health Assessment Questionnaire/Routine Assessment of Patient Index Data) Scores in RA Patients Who Have Depression According to a Screening Questionnaire
Rosa Morlà¹, Mariam Riad ², Raul Castellanos-Moreira ³, Virginia Ruiz-Esquide ⁴, Raimon Sanmarti ⁵, Jose Gomez-Puerta ⁶, Theodore Pincus ² and Isabel Castrejon ², ¹Rheumatology Unit, Xarxa Sanitaria Santa Tecla, Tarragona. Rheumatology, Fundacio Clinic, Barcelona, Barcelona, Spain, ²Division of Rheumatology, Rush University Medical Center, Chicago, IL, ³Rheumatology Department. Hospital Clínic Barcelona, Barcelona, Catalonia, Spain, ⁴Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Catalonia, Spain, ⁵Department of Rheumatology, Hospital Clínic, Barcelona, Barcelona, Spain, ⁶Servei de Rheumatologia, Hospital Clinic Universtari, Barcelona, Barcelona, Catalonia, Spain
Background/Purpose: Depression in rheumatoid arthritis (RA) patients may be pre-existent, amplified, or may develop after the onset of RA1. The Patient Health Questionnaire (PHQ9) is…
Abstract Number: 472 • 2019 ACR/ARP Annual Meeting
Sleep Quality in Women with Rheumatoid Arthritis Is Associated with Disease Activity and Depressive Symptoms
Deborah Da Costa¹, Teresa Szlachetka ² and Diane Lacaille ³, ¹McGill University, Montreal, QC, Canada, ²University of British Columbia, Vancouver, BC, Canada, ³Arthritis Research Canada and University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Sleep disturbances, including difficulty initiating sleep, maintaining sleep, and/or early morningawakenings are prevalent in persons with rheumatoid arthritis (RA) and can significantly impact quality…
Abstract Number: 516 • 2019 ACR/ARP Annual Meeting
Impact of Baseline Demographics and Disease Activity on Outcomes in Patients with Rheumatoid Arthritis Receiving Upadacitinib
Michael Weinblatt¹, Eduardo Mysler ², Andrew Östör ³, Aaron Broadwell ⁴, Slawomir Jeka ⁵, Kendall Dunlap ⁶, Jessica Suboticki ⁶, Jose Jeffrey Enejosa ⁶, Barbara Hendrickson ⁶, Sheng Zhong ⁶, Katya Cherny ⁶ and Grace Wright ⁷, ¹Brigham and Women's Hospital, Boston, MA, USA, Boston, MA, ²Organización Medica de Investigación, Buenos Aires, Argentina, Buenos Aires, Argentina, ³Cabrini Medical Centre, Monash University, Malvern, Australia, Malvern, Australia, ⁴Rheumatology and Osteoporosis Specialists, Shreveport, LA, USA, Shreveport, LA, ⁵University Hospital Bydgoszcz no 2, CM UMK, Bydgoszcz, Poland, ⁶AbbVie Inc., North Chicago, IL, USA, North Chicago, IL, ⁷New York University Langone Medical Center, New York, NY, USA, New York
Background/Purpose: Upadacitinib (UPA), an oral selective JAK1 inhibitor, has demonstrated favorable efficacy and acceptable safety in five Phase 3 global studies in patients with moderately…

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