Abstracts tagged "radiography and rheumatoid arthritis (RA)"

Abstract Number: 462 • 2015 ACR/ARHP Annual Meeting
Radiographic Progression in Patients with Early Rheumatoid Arthritis Has Not Become Milder over the Past Decades
Carola Wassenberg¹, Rolf Rau², Siegfried Wassenberg³, Dietmar Krause⁴ and Christoph Fiehn⁵, ¹Radiology, Friedrich Ebert Krankenhaus, Neumünster, Germany, ²Expert in Rheumatology, Düsseldorf, Germany, ³Rheumaklinik, Themistocles Gluck hospital - Rheumazentrum Ratingen, Ratingen, Germany, ⁴Dept. for Medical Informatics, Biometry and Epidemiology, Ruhr University, Bochum, Germany, ⁵ACURA Centre for Rheumatic Diseases, Baden-Baden, Germany
Background/Purpose: Retrospective studies have promoted the idea that RA has become a milder disease over the past decades[i], [ii]. These findings are questionable because of…
Abstract Number: 1310 • 2015 ACR/ARHP Annual Meeting
Efficacy of Abatacept in Patients with Rheumatoid Arthritis Assessed By MRI Scans of Bilateral Hands
Yuji Kukida¹, Akiko Kasahara¹, Takahiro Seno^1,2, Yu Isoda¹, Tomoya Sagawa¹, Takuya Inoue¹, Naoka Kamio¹, Risa Sagawa¹, Takashi Kida¹, Amane Nakabayashi¹, Hidetake Nagahara³, Ken Murakami¹, Aihiro Yamamoto¹, Satoshi Morita⁴, Hirotoshi Ito⁵, Masataka Kohno¹ and Yutaka Kawahito¹, ¹Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ²Department of Rheumatic Diseases and Joint Function, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ³Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ⁴Department of Biomedical Statistics and Bioinformatics, Kyoto University Graduate School of Medicine, Kyoto, Japan, ⁵Department of Radiology, Kajiicho Medical Imaging Center, Kyoto, Japan
Background/Purpose: Previous radiographic and MRI studies have demonstrated that abatacept (ABT) can inhibit the progression of bone and joint destruction in patients with rheumatoid arthritis…
Abstract Number: 1321 • 2015 ACR/ARHP Annual Meeting
Inter-Reader Agreement of a Novel Method of Radiographic Scoring of Rheumatoid Arthritis
Priyanka Vashisht¹, Abhijeet Danve², Harlan Sayles³, Ted R. Mikuls³ and Alan R. Erickson⁴, ¹Division of Rheumatology and Department of Immunology, University of Nebraska Medical Center, Omaha, NE, ²Rheumatology, University of Nebraska Medical Center, Omaha, NE, ³University of Nebraska Medical Center, Omaha, NE, ⁴Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Although widely used in research studies, most of the radiographic scoring systems for Rheumatoid Arthritis (RA) are not feasible in routine clinical practice as…
Abstract Number: 1324 • 2015 ACR/ARHP Annual Meeting
Simplified Larsen Erosion Score Is Compatible with the Classic Larsen Score but Less Time Consuming in Practice
Michael Ziegelasch¹, Alf Kastbom², Thomas Skogh³, Kristina Forslind⁴ and Alf Kastbom, ¹Rheumatology Department, Rheumatology/AIR, Linkoping, Sweden, ²Department of Clinical and Experimental Medicine, Rheumatology/AIR, Linköping, Sweden, ³IKE/Rheumatology, Linköping University, Linköping, Sweden, ⁴Department of Medicine, Helsingborgs Lasarett, Section of Rheumatology, Helsingborg, Sweden
Background/Purpose: Untreated rheumatoid arthritis (RA) often leads to joint space narrowing (JSN) and erosions in synovial joints. Scoring systems like Sharp van der Heijde and…
Abstract Number: 2059 • 2015 ACR/ARHP Annual Meeting
Tumor Necrosis Factor Inhibitor Tapering Induced Radiographic Progression Is Driven By Weighted Mean Disease Activity over Time, Not Flaring or Lower TNFi Exposition
Alfons A. den Broeder¹, Chantal A.M. Bouman¹, Aatke van der Maas², Frank H.J. van den Hoogen¹, Noortje van Herwaarden¹ and R. Landewe³, ¹Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ²Hengstdal 3, Sint Maartenskliniek, Nijmegen, Netherlands, ³Department of Internal Medicine, Division of Rheumatology, University Hospital Maastricht, Maastricht, Netherlands
Background/Purpose: DRESS, a randomized controlled strategy trial (RCT)1investigating disease activity guided tapering of etanercept and adalimumab compared to usual care in RA patients, indicated that…
Abstract Number: 2589 • 2015 ACR/ARHP Annual Meeting
Associations Between 49 Susceptibility SNPs and Disease Activity Including Radiographic Damage in Early Untreated Rheumatoid Arthritis
Christian G. Ammitzbøll¹, Rudi Steffensen², Martin Bøgsted^3,4, Kaspar Rene Nielsen², Torkell Ellingsen⁵, Merete Lund Hetland⁶, Peter Junker⁵, Jan Pødenphant⁷, Mikkel Østergaard⁸, Julia Johansen⁹, Kim Hørslev-Petersen¹⁰ and Kristian Stengaard-Pedersen¹, ¹Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ²Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark, ³Department of Haematology, Aalborg University Hospital, Aalborg, Denmark, ⁴Department of Mathematical Sciences, Aalborg University, Aalborg, Denmark, Aalborg, Denmark, ⁵Department of Rheumatology, Odense University Hospital, Odense, Denmark, ⁶DANBIO, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Glostrup, Denmark, ⁷Department of Rheumatology, Copenhagen University Hospital at Gentofte, Glostrup, Denmark, ⁸Rigshospitalet-Glostrup, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, Glostrup, Denmark, ⁹Departments of Medicine and Oncology, Copenhagen University Hospital at Herlev, Copenhagen, Denmark, ¹⁰Rheumatology, Research Unit at King Christian X Hospital for Rheumatic Diseases, Graasten, Graasten, Denmark
Background/Purpose: Genome-wide association studies (GWAS) and meta-GWAS studies have identified >50 single nucleotide-polymorphisms (SNPs) that are associated with susceptibility to rheumatoid arthritis (RA). It is,…
Abstract Number: 2601 • 2015 ACR/ARHP Annual Meeting
The Multi-Biomarker Disease Activity Score in a TNF Inhibitor Tapering Study in Rheumatoid Arthritis Patients: Predictive Value for Successful Tapering, Flaring and Radiographic Progression
Chantal A.M. Bouman¹, Aatke van der Maas¹, Noortje van Herwaarden¹, Eric H. Sasso², Frank H.J. van den Hoogen¹ and Alfons A. den Broeder¹, ¹Rheumatology, Sint Maartenskliniek, Nijmegen, Netherlands, ²Crescendo Bioscience Inc., South San Francisco, CA
Background/Purpose: We evaluated the predictive value of the multi-biomarker disease activity (MBDA) score for clinical outcomes and radiographic progression in a TNFi tapering study in…
Abstract Number: 2693 • 2015 ACR/ARHP Annual Meeting
Comparing Eight Year Clinical and Radiographic Outcome in Two Cohorts of Patients with Rheumatoid Arthritis
Maria LE Andersson¹, Kristina Forslind² and Ingiäld Hafström³, ¹R&D Centre Spenshult,Halmstad, Halmstad, Sweden, ²Department of Medicine, Helsingborgs Lasarett, Section of Rheumatology, Helsingborg, Sweden, ³Rheumatology Dept, Karoliska Institute, Stockholm, Sweden
Background/Purpose: To compare patient and disease characteristics over the first 8 years of disease in a large inception cohort of early RA patients included 1992…
Abstract Number: 350 • 2015 ACR/ARHP Annual Meeting
Atypical Femur Fracture in Rheumatoid Arthritis Patients Treated with Bisphosphonates: A Nested Case-Control Study
JungHee Koh¹, Ji Hyeon Ju², Min Kyung Chung³, Ji Hun Kim³, Seung Min Jung⁴, Ji Yeon Lee², Jennifer Lee³, Seung-Ki Kwok⁵ and Sung-Hwan Park³, ¹Seochogu, Banpodaero, 222, Division of Rheumatology, Department of Internal Medicine, College of Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ³Division of Rheumatology, Department of Internal Medicine, College of Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, school of medicine, The catholic university of Korea, Seoul, South Korea, ⁵[email protected], Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: Patients with rheumatoid arthritis (RA) are diagnosed with osteoporosis earlier than and those without RA, and are therefore exposed to Bisphosphonates (BPs) for longer.…
Abstract Number: 439 • 2015 ACR/ARHP Annual Meeting
Progression of Radiographic Joint Destruction in Patients with Rheumatoid Arthritis Treated with a Biologic Agent in Combination with Methotrexate Versus a Biologic Alone: A Systematic Review and Meta-Analysis of Randomized Trials
Tanja Schjødt Jørgensen¹, Simon Tarp¹, Daniel E. Furst², Anna Døssing¹, Peter C. Taylor³, Henning Bliddal¹ and Robin Christensen¹, ¹Musculoskeletal Statistics Unit, The Parker Institute, Department of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, ²Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ³Nuffield Dept. of Orthopaedics, Rheumatology and Musculoskeletal, Sciences, Kennedy Institute of Rheumatology, University of Oxford,, Oxford, United Kingdom
Background/Purpose : One of the frequently claimed advantages of biologic agents is their potential to arrest radiographic progression. The ability of disease-modifying antirheumatic drugs (DMARDs;…
Abstract Number: 2925 • 2014 ACR/ARHP Annual Meeting
Serum MMP-3 Predicts a Subgroup with No Radiographic Progression in Rheumatoid Arthritis Patients with Low-Dose Methotrexate (MTX) Monotherapy
Kazuko Shiozawa¹, Takashi Yamane², Miki Murata¹, Chihiro Tanaka¹, Noriaki Yo², Ryosuke Yoshihara¹, Yasushi Tanaka¹, Ken Tsumiyama³ and Shunichi Shiozawa⁴, ¹The Rheumatic Diseases Center, Kohnan Kakogawa Hospital, Kakogawa, Japan, ²Kohnan Kakogawa Hospital, Kakogawa, Japan, ³Department of Rheumatology, Kyushu University Beppu Hospital, Beppu, Japan, ⁴Department of Medicine, Rheumatic Diseases Unit, Kyushu University Beppu Hospital, Beppu, Japan
Background/Purpose: Studies have shown that treating rheumatoid patients with methotrexate (MTX) monotherapy initially and later providing an option to step up to combination therapy produces…
Abstract Number: 2913 • 2014 ACR/ARHP Annual Meeting
Does Corticosteroid Therapy at Disease Onset Influence Disease Progression of RA? Results from the Swiss Prospective Observational Cohort
Ruediger Mueller¹, Nazim Reshiti², Toni Kaegi³, Axel Finckh⁴, Hendrik Schulze-Koops⁵, Michael H. Schiff⁶ and Johannes von Kempis⁷, ¹Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, ²Division of Rheumatology, St. Gallen, Switzerland, ³Division of Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, ⁴Rheumatology, Geneva University Hospital, Geneva, Switzerland, ⁵Division of Rheumatology and Clinical Immunology, University of Munich, Munich, Germany, ⁶School of Medicine, University of Colorado, Denver, CO, ⁷Rheumatology, St. Gallen Hospital, CH- 9007 St.Gallen, Switzerland
Background/Purpose Anti-inflammatory and disease-modifying properties of glucocorticoids (GCs) have been demonstrated in patients with rheumatoid arthritis (RA). Better outcomes in trials by combinations of synthetic…
Abstract Number: 2914 • 2014 ACR/ARHP Annual Meeting
The Clinical and Radiographic Course of Early Undifferentiated Arthritis Under Treatment Is Not Dependent on the Amount of Erosions at Diagnosis. Results from the Swiss Prospective Observational Cohort
Ruediger Mueller¹, Toni Kaegi², Sarah Haile³ and Johannes von Kempis⁴, ¹Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, ²Division of Rheumatology, Kantonsspital St. Gallen, St. Gallen, Switzerland, ³Division of Biostatistics, Institute for Social and Preventive Medicine,, University of Zurich, Switzerland, Zurich, Switzerland, ⁴Rheumatology, St. Gallen Hospital, CH- 9007 St.Gallen, Switzerland
Background/Purpose To analyse whether early arthritis patients who do not fulfil the ACR/EULAR 2010 classification criteria for rheumatoid arthritis (RA) have a different course of…
Abstract Number: 2387 • 2014 ACR/ARHP Annual Meeting
Relation Between Disease Activity Indices and Their Individual Components and Radiographic Progression in Rheumatoid Arthritis: A Systematic Literature Review
Victoria Navarro-Compán¹, Ana Maria Gherghe², Josef Smolen³, Daniel Aletaha⁴, Robert B. M. Landewé^5,6 and Désirée van der Heijde⁷, ¹Leiden University Medical Center, Leiden, Netherlands, ²Internal Medicine and Rheumatology, Carol Davila University of Medicine and Pharmacy & Cantacuzino Hospital, Bucharest, Romania, ³Division of Rheumatology, Department of Internal Medicine III,, Medical University of Vienna and Hietzing Hospital, Vienna, Austria, ⁴Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁵Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁶Atrium Medical Center, Heerlen, Netherlands, ⁷Dept of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

Background/Purpose: Composite indices and single items are available to monitor disease activity in rheumatoid arthritis (RA). Their relation to radiographic progression is an important aspect…
Abstract Number: 2131 • 2014 ACR/ARHP Annual Meeting
the Impact of Patient-Reported Flares on Radiographic Progression in Rheumatoid Arthritis Patients with Low-Disease Activity: Secondary Analyses from a Randomized Trial
Dorota Kuettel¹, Jette Primdahl^2,3,4,5, Lykke Midtbøll Ørnbjerg⁶, Hans Christian Horn⁷, Robin Christensen⁸ and Kim Hørslev-Petersen⁹, ¹Rheumatological, King Christian X's Hospital for Rheumatic Diseases, Graasten, Denmark, ²Rheumatology, King Christian X's Hospital for Rheumatic Diseases, Graasten, Denmark, ³Institute for Regional Health Research, University of Southern Denmark, Graasten, Denmark, ⁴Hospital of Southern Jutland, Soenderborg, Denmark, ⁵Danbio Registry, Glostrup, Denmark, ⁶Copenhagen Center for Arthritis Reasearch, Center for Rheumatology and Spine diseases, Glostrup Hospital, Copenhagen, Denmark, ⁷Internal Medicine/Rheumatology, Odense University Hospital, Odense, Denmark, ⁸Rheumatology, MSU, The Parker Institute, Copenhagen University Hospital, Frederiksberg, Denmark, ⁹Research Unit at King Christian X Hospital for Rheumatic Diseases, Graasten, Denmark
Background/Purpose Flares, potentially disabling and disease worsening even when a patient is in low disease activity, are common features in patients with rheumatoid arthritis (RA)…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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