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Abstracts tagged "quality of life"

  • Abstract Number: 0877 • ACR Convergence 2020

    Improvements in Global Functioning and Health-related Quality of Life and Their Association with Disease Activity and Functional Improvement in Patients with Active Ankylosing Spondylitis Treated with Upadacitinib

    Uta Kiltz1, Joachim Sieper2, Atul Deodhar3, Patrick Zueger4, In-Ho Song4, Naijun Chen4 and Désirée van der Heijde5, 1Rheumazentrum Ruhrgebiet, Herne, and Ruhr-University Bochum, Herne, Germany, 2Charité Universitätsmedizin Berlin, Berlin, Germany, 3Oregon Health & Science University, Portland, OR, 4AbbVie Inc., North Chicago, IL, 5Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Upadacitinib (UPA) has been shown to be effective and well tolerated in patients with active ankylosing spondylitis (AS) [1]. However, improvements in global functioning…
  • Abstract Number: 1284 • ACR Convergence 2020

    Application of a Novel Method for Determination of Muscle Mass Relative to Fat Mass in Women with Systemic Lupus Erythematosus and Association with Disability

    Sarah Lieber1, Patricia Katz2, Joshua Baker3, Deanna Jannat-Khah4, Dina Sheira1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of California, San Francisco, Novato, CA, 3University of Pennsylvania, Philadelphia, PA, 4Hospital for Special Surgery, New York City, NY

    Background/Purpose: Patients with SLE are at risk for both skeletal muscle loss and increased adiposity, which may predispose to worse health-related quality of life. Decreased…
  • Abstract Number: 0166 • ACR Convergence 2020

    Prevalence and Impact of Unacceptable Symptom State Among Patients with Psoriatic Arthritis: Results from the National Psoriasis Foundation’s 2019 Annual Survey

    Alexis Ogdie1, George Gondo2, Joseph Merola3, Stacie Bell4 and Alice Gottlieb5, 1University of Pennsylvania, Philadelphia, PA, 2National Psoriasis Foundation, Portland, OR, 3Brigham and Women's Hospital, Harvard Medical School, Newton, MA, 4National Psoriasis Foundation, Portland, 5Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY

    Background/Purpose: Despite many efficacious therapies for PsA, many patients do not achieve remission.  Ongoing disease activity leads to many downstream effects including diminished functional ability,…
  • Abstract Number: 0900 • ACR Convergence 2020

    Achievement of Low Disease Activity According to BASDAI with Ixekizumab in Patients with Axial Spondyloarthritis: 16-Week Results from the COAST Trials

    Denis Poddubnyy1, Xavier Juanola2, Clément Prati3, Hagen Russ4, Yves Schymura4, Soyi Liu-Leage5, Mani Haschemi Nassab4 and Jean Dudler6, 1Charité – Universitätsmedizin Berlin, Berlin, Germany, 2Rheumatology Service, University Hospital Bellvitge, IDIBELL, Barcelona, Spain, Barcelona, Spain, 3Service de Rhumatologie, Hôpital Jean-Minjoz , Besançon, France, Besançon, France, 4Eli Lilly and Company, Indianapolis, Indiana, USA, Indianapolis, IN, 5Eli Lilly and Company, Indianapolis, IN, 6Department of Rheumatology, HFR Fribourg - Hospital Cantonal, Fribourg, Switzerland, Fribourg, Switzerland

    Background/Purpose: The efficacy of ixekizumab (IXE), a selective interleukin-17A antagonist, was assessed in patients (pts) with axial SpA (axSpA) in three Phase 3, randomized, double-blind,…
  • Abstract Number: 1285 • ACR Convergence 2020

    Association of Frailty with Disability Is Not Attenuated by Lean Body Mass in Women with SLE

    Sarah Lieber1, Patricia Katz2, Joshua Baker3, Deanna Jannat-Khah4, Dina Sheira1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of California, San Francisco, Novato, CA, 3University of Pennsylvania, Philadelphia, PA, 4Hospital for Special Surgery, New York City, NY

    Background/Purpose: Frailty has been associated with disability and mortality in SLE. Whether this association is confounded by sarcopenia, a degenerative loss of muscle mass and…
  • Abstract Number: 0167 • ACR Convergence 2020

    Rheumatoid Arthritis Patient Phenotypes from a Digital Health Coaching Engagement Program

    Jonathan Patterson1, Kirby Magid2, Dhiren Patel3 and Matt Allison3, 1Pack Health, Birmingham, AL, 2University of North Carolina at Charlotte, Charlotte, 3Pack Health, Birmingham

    Background/Purpose: The goal of this study was to examine whether cluster analysis could be used to identify homogeneous subgroups of engagement in RA patients enrolled…
  • Abstract Number: 0919 • ACR Convergence 2020

    Determinants of Health-related Quality of Life in Systemic Sclerosis

    Nina van Leeuwen1, Jacopo Ciaffi2, Sophie Liem2, Thomas Huizinga2 and Jeska de Vries-Bouwstra2, 1LUMC, Leiden, Netherlands, 2Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Systemic Sclerosis (SSc) is a heterogeneous disease, in which multiple manifestations are associated with considerable morbidity and mortality. Cross sectional studies have shown that…
  • Abstract Number: 1314 • ACR Convergence 2020

    Fatigue in Psoriatic Arthritis (PsA): Prevalence in Patients from the US and Europe, and Impact on Quality of Life and Work Productivity

    Jessica Walsh1, Kaleb Michaud2, Elizabeth Holdsworth3, Steven Peterson4, Nicola Booth3, Sophie Meakin3, Soumya Chakravarty5, James Piercy3 and Alexis Ogdie6, 1University of Utah School of Medicine, George E. Wahlen Veteran Affairs Medical Center, Salt Lake City, UT, 2University of Nebraska Medical Center, Omaha, NE, 3Adelphi Real World, Bollington, United Kingdom, 4Janssen Immunology Global Commercial Strategy Organization, Horsham, PA, 5Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, 6Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Fatigue is an important aspect of PsA for patients.  Understanding the impact of fatigue on patient reported outcomes is important for effective management of…
  • Abstract Number: 0168 • ACR Convergence 2020

    Impact of Adalimumab (Humira) Therapy on Ocular Inflammation, Selected Health Care Resource Utilization, and Patient-Reported Outcomes in Patients with Active Non-infectious Intermediate, Posterior, or Panuveitis in Routine Clinical Practice

    Uwe Pleyer1, Salem Almutairi2, Conor Murphy3, Rola Hamam4, Karina Julian5, Shereen Hammad6, Orsolya Nagy7, Zohar Habot-Wilner8, Zsuzsanna Szepessy9, Yan Guex-Crosier10 and Sofia Androudi11, 1Charité Universitätsmedizin Berlin, Klinik für Augenheilkunde, Berlin, Germany, 2Al-Bahar Ophthalmology Center - Al-Sabah Hospital, Kuwait City, Kuwait, 3Royal Victoria Eye & Ear Hospital, Dublin, Ireland, 4American University of Beirut, Beirut, Lebanon, 5Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 6AbbVie Biopharmaceuticals GmbH, Dubai, United Arab Emirates, 7AbbVie Kft, Budapest, Hungary, 8Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, Israel, 9Semmelweis University, Budapest, Hungary, 10Jules-Gonin Eye Hospital, Department of Ophthalmology, University of Lausanne, Lausanne, Switzerland, 11University of Thessaly, Larissa, Greece

    Background/Purpose: VISUAL clinical trials demonstrated efficacy and safety of adalimumab (ADA) in patients with active and inactive non-infectious, intermediate, posterior, or panuveitis (NIIPPU).1-3 The purpose…
  • Abstract Number: 0930 • ACR Convergence 2020

    Sexual Health Impairment in 90 Female Patients with Systemic Sclerosis

    Barbora Hermankova1, Maja Spiritovic2, Sabina Oreska3, Hana Storkanova4, Hana Smucrova5, Karel Pavelka6, Jiří Vencovský6, Ladislav Šenolt6, Radim Becvar4 and Michal Tomcik4, 1Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Hlavni mesto Praha, Czech Republic, 2Faculty of Physical Education and Sport, Charles University, Prague, Czech Republic, Prague, Czech Republic, 3Institute of Rheumatology, Prague, Czech Republic. Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Praha 2, Czech Republic, 4Institute of Rheumatology, Prague, Czech Republic. Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic, 5Institute of Rheumatology, Prague, Czech Republic, Prague, Czech Republic, 6Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic

    Background/Purpose: Systemic sclerosis (SSc) is a chronic, multisystem, connective tissue disorder characterized by fibrosis of the skin and internal organ involvement. These serious clinical manifestations…
  • Abstract Number: 1341 • ACR Convergence 2020

    Improvement in Patient-Reported Outcomes in Patients with Psoriatic Arthritis with Inadequate Response to Non-Biologic DMARDs Treated with Upadacitinib versus Placebo or Adalimumab: Results from a Phase 3 Study

    Vibeke Strand1, Philip Mease2, Enrique Soriano3, Mitsumasa Kishimoto4, Carlo Salvarani5, Nemanja Damjanov6, Jaclyn K Anderson7, Erin Blondell7, Patrick Zueger7, Christopher Saffore7 and Dafna Gladman8, 1Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 2Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, 3Department of Public Health, Instituto Universitario, Escuela de Medicina Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Rheumatology Unit, Internal Medicine Services, Hospital Italiano de Buenos Aires, Capital Federal, Buenos Aires, Argentina, 4Department of Nephrology and Rheumatology, Kyorin University School of Medicine, Yokohama, Japan, 5Rheumatology Units, University of Modena and Reggio Emilia, and Azienda USL-IRCCS di Reggio Emilia, REGGIO EMILIA, Italy, 6University of Belgrade Medical School, Belgrade, Serbia, 7AbbVie Inc., North Chicago, IL, 8Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada

    Background/Purpose: Patient-reported outcomes (PROs) are important when evaluating treatment benefits in PsA. We present an analysis of PRO data from the SELECT-PsA 1 study.Methods: SELECT-PsA…
  • Abstract Number: 0198 • ACR Convergence 2020

    A Prospective Cohort Study of Vehicle Control as a Measure of Driving Performance in Patients with Rheumatoid Arthritis

    Kaleb Michaud1, Jennifer Merickel1, Yeongjin Gwon1, Harlan Sayles1, Haley Kampschnieder1, Rebecca Hiebert1, Alison Petro1, Bryant England1, Matthew Rizzo1 and Ted Mikuls1, 1University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Automobile driving is an instrumental activity of daily living. Owing to symptoms and functional impairment, patients with rheumatoid arthritis (RA) rely disproportionately on driving…
  • Abstract Number: 1011 • ACR Convergence 2020

    Effectiveness, Safety and Quality of Life with Tofacitinib Treatment in Adult Patients with Rheumatoid Arthritis Under Routine Clinical Care: First Interim Results from a German Non-Interventional, Prospective, Multi-Center Study

    Frank Behrens1, Ulrich Prothmann2, Thilo Klopsch3, Ann-Dörthe Holst4, Lisa Blindzellner5, Olaf Behmer5, Pascal Klaus5, Thomas Meng5 and Peter-Andreas Löschmann5, 1CIRI/Rheumatology & Fraunhofer IME, Research Division Translational Medicine and Pharmacology, Goethe University Hospital, Frankfurt, Hessen, Germany, 2Knappschaftsklinikum Saar, Püttlingen, Saarland, Germany, 3Rheumatological Practice, Neubrandenburg, Mecklenburg-Vorpommern, Germany, 4Specialist Practice for General Medicine incl. Rheumatology and Acupuncture, Ludwigslust, Mecklenburg-Vorpommern, Germany, 5Pfizer Pharma GmbH, Berlin, Berlin, Germany

    Background/Purpose: Tofacitinib is an orally applied Janus kinase inhibitor, which is approved for rheumatoid arthritis (RA) treatment in the USA since 2012, so that ‘real…
  • Abstract Number: 1371 • ACR Convergence 2020

    Improvement in Patient-Reported Outcomes for Upadacitinib versus Placebo Among Patients with Psoriatic Arthritis and an Inadequate Response to Biologic Disease-Modifying Anti-Rheumatic Drugs

    Vibeke Strand1, Filip Van den Bosch2, Roberto Ranza3, Ying Ying Leung4, Edit Drescher5, Apinya Lertratanakul6, Ralph Lippe7, Christopher Saffore6, Patrick Zueger6 and Peter Nash8, 1Division of Immunology/Rheumatology, Stanford University, Palo Alto, CA, 2Ghent University Hospital, Ghent, Belgium, 3Hospital de Clinicas, Universidade Federal de Uberlândia, Uberlândia, Brazil, 4Department of Rheumatology & Immunology, Singapore General Hospital, Singapore, Singapore, 5Veszprém Csolnoky Ferenc County Hospital, Veszprém, Hungary, 6AbbVie Inc., North Chicago, IL, 7AbbVie Deutschland GmbH & Co. KG, Wiesbaden, Germany, 8School of Medicine Griffith University, Brisbane, Queensland, Australia

    Background/Purpose: The efficacy and safety of upadacitinib (UPA), a selective Janus kinase inhibitor, in patients with PsA is under investigation in Phase 3 clinical trials.…
  • Abstract Number: 0249 • ACR Convergence 2020

    Validation of the SIMPLE Index for Disease Activity of Systemic Lupus Erythematosus in Chinese Patients

    Chi Chiu Mok1, Ling Yin Ho1, Kar Li Chan2 and Meenakshi Jolly3, 1Tuen Mun Hospital, Hong Kong, China (People's Republic), 2Tuen Mun Hospital, Hong Kong, Hong Kong, 3Rush University, Chicago, IL

    Background/Purpose: The SIMPLE (SIMple Disease Assessment for People with Lupus Erythematosus) index is a composite numeric tool that captures disease activity from patients’ self-assessment with…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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