Abstracts tagged "Pulmonary Involvement"

Abstract Number: 944 • 2017 ACR/ARHP Annual Meeting
Long-Term Survival and Follow-up of Anti-Th/to Antibody Positive Systemic Sclerosis Patients
Devon Charlton¹, Maureen Laffoon², Thomas A. Medsger Jr.³ and Robyn T. Domsic⁴, ¹Division of Rheumatology and Clinical Immunology, University of Pittsburgh Medical Center, Pittsburgh, PA, ²Rheumatology, University of Pittsburgh Medical Center, Pittsburgh, PA, ³Department of Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA, ⁴Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Anti-Th/To antibody is an autoantibody associated with systemic sclerosis (SSc), occurring in 5-10% of patients. To date, only relatively small case series have described…
Abstract Number: 947 • 2017 ACR/ARHP Annual Meeting
Norway As a National Reference Population for Systemic Sclerosis; Preliminary Results from a Complete, Nationwide Cohort
Anna-Maria Hoffmann-Vold¹, Håvard Fretheim¹, Anne Kristine Halse², Marit Seip³, Marianne Wallenius⁴, Helle Bitter⁵, Torhild Garen¹, Oyvind Midtvedt¹ and Øyvind Molberg¹, ¹Oslo University Hospital, Oslo, Norway, ²Haukeland University Hospital, Bergen, Norway, ³University Hospital of North Norway, Tromso, Norway, ⁴St. Olav's University Hospital, Trondheim, Norway, ⁵Hospital of Southern Norway, Kristiansand, Norway
Background/Purpose: To fully understand the impact of Systemic sclerosis (SSc) there is a need to complement existing multi-center registry data with novel, unbiased, high resolution…
Abstract Number: 1276 • 2017 ACR/ARHP Annual Meeting
Nail Fold Capillary Changes Are Associated with Pulmonary, but Not with Cardiac Involvement in Juvenile Dermatomyositis
Zoltán Barth^1,2,3, Thomas Schwartz^2,4, Berit Flatø^5,6, Akos Koller^7,8, May Brit Samersaw-Lund⁹, Ivar Sjaastad^10,11 and Helga Sanner⁶, ¹Bjorknes College, Oslo, Norway, ²Oslo University Hospital and University of Oslo, Institute for Experimental Medical Research, Oslo, Norway, ³Medical School, University of Pecs, Institute for Translational Medicine, Pecs, Hungary, ⁴Institute for Experimental Medical Research, Institute for Clinical Medicine, University of Oslo, Oslo, Norway, ⁵Institute for Clinical Medicine, University of Oslo, Oslo, Norway, Oslo, Norway, ⁶Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ⁷University of Physical Education, Institute of Natural Sciences, Budapest, Hungary, ⁸Medical School, University of Pecs, Department of Neurosurgery, Pecs, Hungary, ⁹Oslo University Hospital, Rikshospitalet, Department of Respiratory Medicine, Oslo, Norway, ¹⁰Department of Cardiology, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ¹¹Institute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway, Oslo, Norway
Background/Purpose: Juvenile dermatomyositis (JDM) is a rare autoimmune disease of unknown origin, characterised primarily by cutaneous rashes and symmetrical weakness of the proximal skeletal muscles.…
Abstract Number: 1697 • 2017 ACR/ARHP Annual Meeting
Unique Characteristics of Scleroderma Among African Americans: A Population Based Study
Sarah M. Compton¹, Richard M. Silver² and Diane L. Kamen³, ¹Internal Medicine, Medical University Of South Carolina, Charleston, SC, ²Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC, ³Medicine/Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC
Background/Purpose: Systemic sclerosis (SSc) is a rare autoimmune disease categorized on the basis of skin involvement as either limited or diffuse cutaneous SSc, the latter…
Abstract Number: 105 • 2017 Pediatric Rheumatology Symposium
Isolated Pediatric Pulmonary Capillaritis: A Comprehensive Single-Center Review of Disease Course, Management, and Prognosis
William Lapin¹, Saimun Singla², Eyal Muscal³ and Manuel Silva-Carmona⁴, ¹Department of Pediatrics, Division of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, ²Department Pediatrics, Division of Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, ³Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, ⁴Department of Pediatrics, Pulmonology Section, Baylor College of Medicine, Texas Children's Hospital, Houston, TX
Background/Purpose: Pediatric diffuse alveolar hemorrhage (DAH) is a life-threatening disorder characterized by pulmonary hemorrhage and respiratory insufficiency. Histologically, DAH with capillary inflammation is known as…
Abstract Number: 1238 • 2016 ACR/ARHP Annual Meeting
Assessment of Mortality and Healthcare Costs Associated with Systemic Sclerosis with and without Lung Involvement
Karina Raimundo¹, Amanda Farr², Ashley Cole³ and Aryeh Fischer⁴, ¹Genentech, Inc., a Member of the Roche Group, South San Francisco, CA, ²Truven Health Analytics, Cambridge, MA, ³Truven Health Analytics, Bethesda, MD, ⁴Medicine / Center for Lungs and Breathing, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Patients with systemic sclerosis (SSc) are at high risk of developing interstitial lung disease (ILD) and/or pulmonary hypertension (PH). These two lung manifestations are…
Abstract Number: 1344 • 2016 ACR/ARHP Annual Meeting
Characteristics, Treatment and Outcome of Severe Pulmonary Hemorrhage Related to Systemic Disease: French Multicentric Study
Adrien Mirouse¹, Antoine Parrot², Jacques Cadranel³, Eric Mariotte⁴, Julien Mayaux⁵, Nicolas Bréchot⁶, Mathieu Vautier⁷, Etienne de Montmollin⁸, Nicolas de Prost⁹, Patrice Cacoub¹⁰ and David Saadooun¹⁰, ¹Service de médecine interne, Hôpital Saint-Antoine, Paris, France, ²Service de pneumologie, Hôpital Tenon, 75020, France, ³Service de pneumologie, Hôpital Tenon, Paris, France, ⁴Service de réanimation médicale, Hôpital Saint-Louis, Paris, France, ⁵Service de pneumologie et réanimation médicale, Hôpital Pitié-Salpêtrière, Paris, France, ⁶Service de réanimation médicale, Hôpital Pitié-Salpêtrière, Paris, France, ⁷Service de médecine interne, CHU de Caen, Caen, France, ⁸Service de réanimation médicale, Hôpital Delafontaine, Saint-Denis, France, ⁹Service de réanimation médicale, Hôpital Henri Mondor, Créteil, France, ¹⁰Assistance Publique-Hôpitaux de Paris (AP-HP), Groupe Hospitalier Pitié-Salpêtrière, Département de Médecine Interne et d’Immunologie clinique, DHU i2B, Inflammation, Immunopathologie, Biothérapie, Université Pierre et Marie Curie, Paris 6, Paris, France, Paris, France
Background/Purpose: pulmonary hemorrhage (PH) may complicate systemic disease. The main objective of this study was to describe characteristics, treatment and outcome of patients presenting severe…
Abstract Number: 1491 • 2016 ACR/ARHP Annual Meeting
M-Ficolin and MAp44 As Potential Markers of Subclinical Cardiovascular Comorbidity; Cardiac Evaluation By Coronary Computer Tomography and Myocardial Deformation of Left Ventricle in Early Rheumatoid Arthritis Patients
Ida G. Louw¹, Christian G. Ammitzböll², Brian Bridal Løgstrup³, Jesper Blegvad-Nissen⁴, Grazina Urbonaviciene⁴, Trine Bay Laurberg⁴, Mette Herly⁵, Agnete H. Nielsen⁴, Steffen Thiel⁶ and Torkell Ellingsen⁵, ¹University of Southern Denmark, Odense, DK, Odense, Denmark, ²Department of Rheumatology, Aarhus University Hospital, Aarhus, DK, Aarhus, Denmark, ³Department of Cardiology, Skejby, Aarhus University Hospital, Aarhus, DK, Aarhus, Denmark, ⁴Diagnostic Centre, University Research Clinic for Innovative Patient Pathways, Silkeborg Regional Hospital, DK, Silkeborg, Denmark, ⁵Department of Rheumatology, Odense University Hospital, Odense, DK, Odense, Denmark, ⁶Institute of Biomedicine, Aarhus University, Aarhus, DK, Aarhus, Denmark
Background/Purpose: 79 DMARD-naïve RA patients with a disease duration < 6 months were included from an inception cohort. Clinical variables, plasma- and serum-M-ficolin and MAp44…
Abstract Number: 1896 • 2016 ACR/ARHP Annual Meeting
Efficacy of Pulmonary Arterial Hypertension-Specific Drugs Combination Therapy in Survival of Patients with Pulmonary Arterial Hypertension Associated with Systemic Sclerosis and Other Connective Tissue Diseases
Sumiaki Tanaka¹, Yu Matsueda¹, Gakuro Abe², Jun Okada³ and Shunsei Hirohata¹, ¹Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan, ²Kitasato University School of Medicine, Sagamihara, Japan, ³Nutritional management, Kitasato Junior Collage of health and Hygienic Sciences, Minami-Uonuma, Japan
Background/Purpose: Survival of patients with pulmonary arterial hypertension (PAH) associated with connective tissue disease (CTD), especially systemic sclerosis (SSc), is poorer than that of patients…
Abstract Number: 2158 • 2016 ACR/ARHP Annual Meeting
Serum Uric Acid Is Positively Associated with Pulmonary Function in Korean Health Screening Examinees: A Cross-Sectional Study
Joong Kyong Ahn¹, Jiwon Hwang², Jae-Uk Song³, Hyemin Jeong⁴, Ji Young Chae⁵, Hyungjin Kim⁴, Hoon-Suk Cha⁴ and Eun-Mi Koh⁴, ¹Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, South Korea, ²Department of Medicine, National Police Hospital, Seoul, Korea, The Republic of, ³Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea, The Republic of, ⁴Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, ⁵Departement of Internal Medicine, Bundang Jesaeng General Hospital, Seongnam, Korea, The Republic of
Background/Purpose: Serum uric acid (SUA) has been shown to be a powerful endogenous antioxidant in the body. The double-edged characteristics of serum uric acid (SUA)…
Abstract Number: 2201 • 2016 ACR/ARHP Annual Meeting
Self-Reported Breathlessness on Exertion Is Associated with Poor Outcomes Among Women with Systemic Lupus Erythematosus (SLE)
Patricia P. Katz¹, Sofia Pedro², Robert S. Katz³, Frederick Wolfe⁴ and Kaleb Michaud⁵, ¹Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, ²National Data Bank for Rheumatic Diseases, Wichita, KS, ³Rush University Medical Center, Chicago, IL, ⁴National Data Bank, Wichita, KS, ⁵University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Breathlessness is often considered as a predictor of functional outcomes in pulmonary disease, but has not been examined in SLE. Methods: Data were from…
Abstract Number: 2659 • 2016 ACR/ARHP Annual Meeting
Respiratory Symptoms in Patients with Primary SjöGren’s Syndrome – a Case-Control Study
Thomas Mandl¹, Peter Olsson¹, Roger Hesselstrand² and Victor Strevens Bolmgren³, ¹Dept of Rheumatology, Skane University Hospital Malmö, Lund University, Malmo, Sweden, ²Department of Clinical Sciences, Section of Rheumatology, Lund University, Lund, Sweden, ³Dept of Rheumatology, Skane University Hospital Malmo, Lund University, Malmo, Sweden
Background/Purpose: To evaluate the amount and impact of respiratory symptoms in patients with primary Sjögren’s syndrome (pSS) and to assess if such symptoms are related…
Abstract Number: 2888 • 2016 ACR/ARHP Annual Meeting
Usefulness of Bosentan in the Prevention of Pulmonary Hypertension in Patients with Systemic Sclerosis
Ivan Castellví¹, Carmen Pilar Simeón², Monica Paola Sarmiento¹, Alfredo Guillen², Cesar Diaz-Torné³, Josep Maria De Llobet Zubiaga¹, Jordi Casademont⁴ and Vicent Fonollosa², ¹Rheumatology, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, Spain, ²Internal Medicine, Hospital Universitari Vall d'Hebron, Barcelona, Spain, ³Rheumatology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ⁴Internal Medicine, Hospital Universitari de la Santa Creu i Sant Pau, Barcelona, Spain
Background/Purpose: Systemic sclerosis (SSc) is a systemic autoimmune disease in which the damage of microcirculation is critical to develop the disease. In SSc, vascular complications…
Abstract Number: 504 • 2016 ACR/ARHP Annual Meeting
Clinical Significance of Multiple Autoantibody Specificities in Rheumatoid Arthritis: The Role of Anti-Citrullinated Alpha-Enolase and Anti-Interferon Inducible Protein 16 Antibodies
Alessia Alunno¹, Onelia Bistoni¹, Federico Pratesi², Valeria Caneparo³, Fabiana Topini¹, Ilaria Puxeddu², Marco De Andrea⁴, Santo Landolfo⁴, Paola Migliorini² and Roberto Gerli¹, ¹Department of Medicine, Rheumatology Unit, University of Perugia, Perugia, Italy, ²Department of Clinical and Experimental Medicine, Clinical Immunology Unit, University of Pisa, Pisa, Italy, ³Department of Translational Medicine, Virology Unit, Novara Medical School, Novara, Italy, ⁴Department of Public Health and Pediatric Sciences, Viral Pathogenesis Unit, Turin Medical School, Torino, Italy
Background/Purpose: Anti-cyclic citrullinated peptide (anti-CCP) auto-antibodies (auto-Abs) represent the current gold standard for the diagnosis of rheumatoid arthritis (RA). However, growing evidence suggests that a…
Abstract Number: 801 • 2016 ACR/ARHP Annual Meeting
Multi-Tissue Gene Expression Pathway Analysis of Emerging Therapeutics in a TGFβ Dependent Mouse Model of Systemic Sclerosis
Emma C. Derrett-Smith^1,2, Shiwen Xu³, Rachel K. Hoyles⁴ and Christopher Denton⁵, ¹Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, London, United Kingdom, ²Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, ³Division of Medicine, Centre for Rheumatology and Connective tissue disease, University College London, London, United Kingdom, ⁴Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom, ⁵Division of Medicine, Centre for Rheumatology and Connective Tissue Disease, University College London, London, United Kingdom
Background/Purpose: We have previously investigated the interplay between TGFβ, BMP, VEGF and endothelin in SSc using the TβRIIΔk-fib strain, a transgenic mouse model in…

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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