ACR Meeting Abstracts

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Abstracts tagged "Pulmonary Involvement"

  • Abstract Number: 1692 • 2014 ACR/ARHP Annual Meeting

    The Additive Value of Nailfold Videocapillaroscopy Patterns to Disease-Specific Autoantibodies in Discrimination of Patients with Systemic Sclerosis at Risk for Severe Organ Involvement

    I.M. Markusse1, J. Meijs2, B. de Boer2, A. a. Schouffoer1, N. Ajmone Marsan3, L. J. M. Kroft4, M. K. Ninaber5, T. W. J. Huizinga2 and J.K. de Vries-Bouwstra6, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Cardiology, Leiden University Medical Center, Leiden, Netherlands, 4Deparment of Radiology, Leiden University Medical Center, Leiden, Netherlands, 5Pulmonology, Leiden University Medical Center, Leiden, Netherlands, 6Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Severe nailfold videocapillaroscopy (NVC) patterns in patients with systemic sclerosis (SSc) are associated with a high risk of organ involvement. SSc-specific autoantibodies seem to…
  • Abstract Number: 1441 • 2014 ACR/ARHP Annual Meeting

    Accelerated Aging in DMARD and Treatment Naive Early Rheumatoid Arthritis Patients Measured By a Stem Cell Assay Is Associated with Increased LDL and Is Linked to Impaired Cardiopulmonary Function

    Torkell Ellingsen1,2,3, Henriette Jørgensen4, Dino Demirovic4, Lone Deibjerg5, Frank Andersen5, Agnete Hedemann-Andersen5, Brian Bridal Løgstrup5,6 and Suresh Rattan4, 1Diagnostic Centre Region, Hospital Silkeborg Denmark, Odense, Denmark, 2The Danish National Registry DANBIO, Odense, Denmark, 3Department of Rheumatology, Odense University Hospital, Denmark, Odense, Denmark, 4Laboratory of Cellular Ageing, Institute of Molecular Biology and Genetics, Århus University, Århus, Denmark, 5Diagnostic Centre Region, Hospital Silkeborg Denmark, Silkeborg, Denmark, 6Cardiology, Skejby Hospital, Århus Universityhosital, Århus, Denmark

    Background/Purpose: The cardiovascular comorbidity seen in early treatment naive rheumatoid arthritis (RA) can be considered as an aspect of ´´accelerated aging``.  Methods: We investigated cell…
  • Abstract Number: 724 • 2014 ACR/ARHP Annual Meeting

    Moderate Decline in Forced Vital Capacity is Associated with a Poor Outcome in Systemic Sclerosis Patients

    Anna-Maria Hoffmann-Vold1, Oyvind Midtvedt2, Torhild Garen3, May Brit Lund4, T. Mogens Aalokken5, Jan Tore Gran2 and Oyvind Molberg6, 1Department of Rheumatology, Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 2Rheumatology, Oslo University Hospital, Oslo, Norway, 3Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 4Department of Respiratory Medicine, Oslo University Hospital Rikshopitalet, Oslo, Norway, 5Department of Radiology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 6Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway

    Background/Purpose: Interstitial lung disease (ILD) is a common manifestation in systemic sclerosis (SSc) and the leading cause of morbidity and mortality. Serial pulmonary function tests…
  • Abstract Number: 2751 • 2014 ACR/ARHP Annual Meeting

    18F-FDG PET/CT in Vascular Disease Due to Behçet’s Syndrome

    Emire Seyahi1, Metin Hallac2, Betul Vatankulu3, Serdal Ugurlu1, Melike Melikoglu4, Sebahattin Yurdakul1 and Hasan Yazici4, 1Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 2Department of Nuclear Medicine, Cerrahpasa Medical Faculty, University Of Istanbul, Istanbul, Turkey, 3Department of Nuclear Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 4Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey

    Background/Purpose 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/CT is considered as a useful tool in assessing active vascular inflammation in large vessel vasculitis. Lower extremity vein…
  • Abstract Number: 2727 • 2014 ACR/ARHP Annual Meeting

    T Cells Trigger Interstitial Pneumonia in Polymyositis

    Akira Takeda1,2, Yasutsugu Fukushima3, Takaji Matsutani4, Yoichiro Haji1, Chisun Min1, Ryo Rokutanda1, Yasuhiro Suyama1, Mitsumasa Kishimoto5, Ken-ichi Yamaguchi1 and Masato Okada6, 1Immuno-Rheumatology Center, St. Luke's International Hospital, Tokyo, Japan, 2Division of Clinical Immunology & Rheumatology, International University of Health and Welfare Hospital, Nasu-shiobara, Japan, 3Department of Pulmonary Medicine and Clinical Immunology, Dokkyo University School of Medicine, Mibu, Japan, 4Laboratory of Immune Regulation, Wakayama Medical University, Ibaraki, Japan, 5St. Luke's International Hospital, Tokyo, Japan, 6Immuno-Rheumatology Center, St. Luke's International Hospital, tokyo, Japan

    Background/Purpose: The lung is frequently affected in connective tissue diseases (CTDs). Polymyositis (PM) is a major CTD characterized by idiopathic inflammatory lesions of muscle and…
  • Abstract Number: 2574 • 2013 ACR/ARHP Annual Meeting

    Early Use of Prostacyclin Therapy Improves Transplant-Free Survival in Patients With Systemic Sclerosis-Related Pulmonary Arterial Hypertension Plus Interstitial Lung Disease

    Elizabeth Volkmann1, Rajan Saggar2, Bryant Torres1, Lynne Yoder2, Robert Elashoff3, Rajeev Saggar4, Harsh Agrawal1, Nabeel Borazan5, Sarah Thomas1 and Daniel Furst1, 1Medicine, University of California, Los Angeles, Los Angeles, CA, 2Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 3Biomath, University of California, Los Angeles, Los Angeles, CA, 4Critical Care Medicine, St. Joseph's Hospital and Medical Center, Phoenix, AZ, 5Medicine, Rheumatology UCLA, Los Angeles, CA

    Background/Purpose: The leading causes of death in systemic sclerosis (SSc) are pulmonary arterial hypertension (PAH) and interstitial lung disease (ILD). Use of PAH therapy in…
  • Abstract Number: 2575 • 2013 ACR/ARHP Annual Meeting

    Utility Of Autoantibody Testing For Predicting Risk Of Pulmonary Arterial Hypertension: A Retrospective Analysis In Routine Autoantibody Laboratory

    Masataka Kuwana1, Yuichiro Shirai1, Hidekata Yasuoka1, Tsutomu Takeuchi1 and Kenichi Masui2, 1Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 2Department of Anesthesiology, National Defense Medical College, Tokorozawa, Japan

    Background/Purpose: Pulmonary arterial hypertension (PAH) is an intractable complication of connective tissue disease (CTD). Current guidelines recommend early detection and intervention for improvement of outcomes.…
  • Abstract Number: 2580 • 2013 ACR/ARHP Annual Meeting

    Does Mycophenolate Mofetil (MMF) Have An Effect On Pulmonary Hemodynamics? Observations From The Pulmonary Hypertension Assessment and Recognition Of Outcomes In Scleroderma (PHAROS) Cohort

    Lesley Ann Saketkoo1, Matthew R. Lammi2, Jessica K. Gordon3, Paula Lauto4 and Virginia D. Steen5, 1LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, 2Section of Pulmonary and Critical Care Medicine, LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, 3Rheumatology, Hospital for Special Surgery, New York, NY, 4Pulmonary and Critical Care Medicine, LSU Health Sciences Center, New Orleans, LA, 5Department of Rheumatology, Georgetown University Medical Center, Washington, DC

    Does Mycophenolate Mofetil (MMF) have an effect on Pulmonary Hemodynamics? Observations from the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma (PHAROS) CohortBackground/Purpose: Systemic…
  • Abstract Number: 2585 • 2013 ACR/ARHP Annual Meeting

    Left Ventricular Dysfunction Reflected By Higher Serum Brain Natriuretic Peptide Accounts For Poorer Prognosis Of Pulmonary Arterial Hypertension Associated With Systemic Sclerosis

    Sumiaki Tanaka1, Yoshiyuki Arinuma1, Tatsuhiko Wada1, Tatsuo Nagai2, Jun Okada3 and Shunsei Hirohata1, 1Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan, 2Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Sagamihara, Japan, 3Nutritional management, Kitasato Junior Collage of health and Hygienic Sciences, Minami-Uonuma, Japan

    Background/Purpose: Recentry, development of potent effective newer drugs for pulmonary arterial hypertension (PAH) have resulted in improving survival of the patients.  However, the prognosis of…
  • Abstract Number: 2072 • 2013 ACR/ARHP Annual Meeting

    Decreased Number Of Circulating NK Cells and Dramatic Lack Of IFN-Gamma Production In Patients With Antisynthetase Syndrome

    Baptiste Hervier1,2, Yves Allenbach3,4, Fleur Cohen-Aubart5, Micheline Pha6, Lenaig Mescam-Mancini7, David Saadoun8, Alexis Mathian5,6, Olivier Benveniste9,10 and Vincent Vieillard1, 1INSERM UMR-S 1135, UPMC, Paris, France, 2Internal Medicine & Clinical Immunology Dpt, Pitié-Salpêtrière Hospital, APHP, Paris, France, 3Internal Medicine Dpt 1, Pitié-Salpêtrière Hospital, APHP, Paris, France, 4INSERM UMR974, UPMC, Paris, France, 5Internal Medicine Dpt 2, Pitié-Salpêtrière Hospital, APHP, Paris, France, 6INSERM UMR-S 945, UPMC, Paris, France, 7Pathology Dpt, University hospital, Grenoble, France, 8DHU 2iB Internal Medicine Referal Center for Autoimmune diseases Pitie Hospital, Paris, France, 9UMR 974, Sorbonne Universités, University Pierre et Marie-Curie-Paris 6, INSERM, Paris, France, 10Internal Medecine Dpt 1, Pitié-Salpêtrière Hospital, APHP, Paris, France

    Background/Purpose: Antisynthetase syndrome (ASS) is a rare autoimmune myositis associated with interstitial lung disease (ILD) and characterized by specific anti-tRNA-synthetase autoantibodies (ARS). To date, the…
  • Abstract Number: 2052 • 2013 ACR/ARHP Annual Meeting

    The Prevalence and Pattern Of Self Reported Joint Symptoms In Cystic Fibrosis

    Carl Orr1, Cormac McCarthy1, Johan Meurling1, Paul G. O'Connell2, Cedric Gunaratnam1,3 and Noel G McElvaney1, 1Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland, 2Rheumatology, Beaumont Hospital, Dublin, Ireland, 3Department of Respiratory Medicine, Beaumont Hospital, Dublin, Ireland

    Background/Purpose: Arthritis in cystic fibrosis (CF) can be very incapacitating, and it is mainly of three types: CF arthritis, hypertrophic osteoarthropathy, and arthritis due to…
  • Abstract Number: 2012 • 2013 ACR/ARHP Annual Meeting

    Gender Influences On Organ Manifestations In a New Orleans Sarcoidosis Population

    Adam Janot1, McCall Walker2, Mary Yu1, Harmanjot K. Grewal3, Matthew R. Lammi4,5 and Lesley Ann Saketkoo6,7, 1Internal Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, 2LSUHSC School of Medicine, New Orleans, LA, 3Rheumatology, Lousiana State University Health Sciences Center, New Orleans, LA, 4Section of Pulmonary and Critical Care Medicine, LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, 5Louisiana State University Health Sciences Center, Pulmonary and Critical Medicine, New Orleans, LA, 6LSU Scleroderma and Sarcoidosis Patient Care and Research Center, New Orleans, LA, 7Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA

    Background/Purpose: Sarcoidosis is a multi-organ disease in which pulmonary manifestations predominate. The skin, eyes, heart, gastrointestinal tract (GI), reticuloendothelial, renal and nervous systems are also…
  • Abstract Number: 1936 • 2013 ACR/ARHP Annual Meeting

    Quality Of Care In Patients At Risk For Pulmonary Involvement:  Assessment Of Pulmonary Screening In Systemic Sclerosis and Myositis Patients In a General Rheumatology Clinic

    Michael G. Indelicato1, Janet E. Lewis2, Vincent J. Giuliano3 and Donald L. Kimpel4, 1Rheumatology, University of Virginia, Charlottesville, VA, 2Rheumatology, University of Virginia School of Medicine, Charlottesville, VA, 3University of Virginia, Charlottesville, VA, 4Rheumatology and Immunology, University of Virginia School of Medicine, Charlottesville, VA

    Background/Purpose: As a quality assessment tool to evaluate patient care in a general Rheumatology Clinic, we determined the frequency of screening for pulmonary hypertension and…
  • Abstract Number: 1814 • 2013 ACR/ARHP Annual Meeting

    The Risk Of Pulmonary Embolism and Deep Venous Thrombosis In Systemic Sclerosis: A Population-Based Cohort Study

    J. Antonio Avina-Zubieta1, Iman Hemmati2, Eric C. Sayre3, Kamran Shojania3,4 and Hyon Choi3,5,6, 1Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, 2Deparment of Medicine and Rheumatology, University of British Columbia, Vancouver, BC, Canada, 3Arthritis Research Centre of Canada, Richmond, BC, Canada, 4Rheumatology, University of British Columbia, Vancouver, BC, Canada, 5Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 6Division of Rheumatology, Allergy, and Immunology Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Data on the risk of pulmonary embolism (PE) and deep venous thrombosis (DVT) in patients with systemic sclerosis (SSc) is lacking. To fill this…
  • Abstract Number: 1775 • 2013 ACR/ARHP Annual Meeting

    Use Of “Computer-Aided Lung Informatics For Pathology Evaluation and Rating” Software In High-Resolution Computed Tomography In Patients With Idiopathic Inflammatory Myopathy and Interstitial Lung Disease

    Katelynn Wilton1, Brian Bartholmai2, Sanjay Kalra3, Cynthia S. Crowson4, Helen Khun4 and Floranne C. Ernste5, 1Mayo Clinic College of Medicine, Rochester, MN, 2Thoracic Radiology, Mayo Clinic, Rochester, MN, 3Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN, 4Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 5Division of Rheumatology, Mayo Clinic Rochester, Rochester, MN

    Background/Purpose: The idiopathic inflammatory myopathies (IIM) are associated with interstitial lung disease (ILD), characterized by parenchymal abnormalities on high-resolution computed tomography (HRCT). We determined the…
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