ACR Meeting Abstracts

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Abstracts tagged "Pulmonary Involvement"

  • Abstract Number: 034 • 2020 Pediatric Rheumatology Symposium

    Chest Computed Tomography Manifestations in Childhood-Onset Systemic Lupus Erythematosus: A Single-Center Cohort Study

    Pooja Patel1, Gunes Orman 2, Manuel Silva Carmona 3, Maria Pereira 4, Marietta De Guzman 5, Danielle Guffey 6, Scott Wenderfer 7 and R. Paul Guillerman 8, 1Baylor College of Medicine, Houston, Texas, 2Edward B. Singleton Department of Radiology, Texas Children's Hospital, Houston, Texas, 3Section of Pulmonology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, 4Assistant Professor, Section of Rheumatology, Division of Pediatrics, Baylor College of Medicine, Houston, Texas, 5Section of Rheumatology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, 6Dan L. Duncan Institute for Clinical and Translational Research, Baylor College of Medicine, Houston, 7Section of Nephrology, Department of Pediatrics, Baylor College of Medicine, Houston, Texas, 8Edward B. Singleton Department of Radiology, Texas Children's Hospital, Houston, Texas

    Background/Purpose: Intrathoracic involvement in adults with systemic lupus erythematosus (SLE) is relatively common, particularly pleural disease. The prevalence of intrathoracic involvement in childhood-onset SLE (cSLE)…
  • Abstract Number: 2341 • 2019 ACR/ARP Annual Meeting

    Findings of Pulmonary Abnormalities on High Resolution Computed Tomography in a Cohort of Rheumatoid Arthritis Patients Without Known Lung Disease

    Scott Matson1, Kevin Deane 2, Christopher Collora 1, Xi Zheng 1, Marie Fester 1, Joyce Lee 1 and M. Kristen Demoruelle 3, 1University of Colorado, Denver, 2University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora, CO, 3University of Colorado Denver, Division of Rheumatology, Aurora, CO, USA, Aurora

    Background/Purpose: Pulmonary manifestations of rheumatoid arthritis (RA) lead to significant morbidity and mortality. Lung manifestations in RA are myriad, however little is known about how…
  • Abstract Number: 2610 • 2019 ACR/ARP Annual Meeting

    Relationship Between Parenchymal and Vascular Features in Systemic Sclerosis-Interstitial Lung Disease: Results from Quantitative Analysis of Chest Computed Tomography

    Cosimo Bruni1, Mariaelena Occhipinti 2, Gianna Camiciottoli 3, Maurizio Bartolucci 4, Michael Pienn 5, Gemma Lepri 1, Alessio Fabbrizzi 3, Alessandra Tottoli 1, Giulia Ciardi 3, Dilia Giuggioli 6, Giovanna Cuomo 7, Francesco Masini 7, Andrea Olschewski 5, Federico Lavorini 3, Stefano Colagrande 8 and Marco Matucci-Cerinic 9, 1Dept. Experimental and Clinical Medicine, Division of Rheumatology, Azienda Ospedaliera Universitaria Careggi – University of Florence, Florence, Italy, 2Dept. Experimental and Clinical Medicine, Div. Pneumology and Div. Radiology II, Azienda Ospedaliera Universitaria Careggi – University of Florence, Florence, Italy, 3Dept. Experimental and Clinical Medicine, Div. Pneumology, Azienda Ospedaliera Universitaria Careggi – University of Florence, Florence, Italy, 4Dept. of Services, Div. Emergency-Urgency Radiology, Azienda Ospedaliera Universitaria Careggi, Florence, Italy, 5Ludwig Boltzmann Institute for Lung Vascular Research, Institute of Physiology, Medical University of Graz, Graz, Austria, 6Rheumatology Unit, University of Modena and Reggio Emilia, Azienda Ospedaliero-Universitaria, Policlinico di Modena, Modena, Italy, 7Division of Internal Medicine, Department of Medical and Surgical Sciences, "Luigi Vanvitelli" University of Campania, Naples, Italy, 8Dept. Experimental and Clinical Medicine, Div. Radiology II, Azienda Ospedaliera Universitaria Careggi – University of Florence, Florence, Italy, 9University of Florence, Department of Medicine, Florence, Italy, Florence, Italy

    Background/Purpose: Interstitial lung disease (ILD) and pulmonary arterial hypertension negatively impact on Systemic sclerosis (SSc) prognosis. Chest computed tomography (CT) is the gold standard in…
  • Abstract Number: 2615 • 2019 ACR/ARP Annual Meeting

    Cumulative Incidence, Survival and Predictors of Pulmonary Arterial Hypertension in Disease Subsets of Systemic Sclerosis: PAH Is Not Increased in Limited vs Diffuse Patients by Adjusted Competing Risk Analysis

    Tatiana Nevskaya 1, Yuxuan Jiang 1, Mianbo Wang 2 and Janet Pope3, 1University of Western Ontario, London, ON, Canada, 2Lady Davis Institute, Jewish General Hospital, Montreal, QC, Canada, 3Western University, London, ON, Canada

    Background/Purpose: Pulmonary arterial hypertension (PAH) is a life-threatening complication of systemic sclerosis (SSc), thought to be more commonly found among the limited cutaneous (lcSSc) compared…
  • Abstract Number: 795 • 2018 ACR/ARHP Annual Meeting

    Frequency and Clinical Associations of Rare Antibodies in a Large Connective Tissue Disease Cohort

    Kristina E.N. Clark1, Corrado Campochiaro2, Lauren V. Host3, Alper Sari4, Svetlana I. Nihtyanova5, Carmen Fonseca6, Christopher P. Denton7 and Voon H. Ong8, 1Centre of Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom, 2Centre for Rheumatology and Connective Tissue Diseases, UCL Division of Medicine, London, United Kingdom, 3Department of Rheumatology and Connective Tissue Disease, University College London, London, United Kingdom, 4Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 5Division of Medicine, Centre for Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom, 6UCL Centre for Rheumatology and Connective Tissue Diseases, London, United Kingdom, 7University College London, London, United Kingdom, 8Division of Medicine, University College London, London, United Kingdom

    Background/Purpose: Connective tissue diseases (CTDs) are characterised by specific autoantibodies which are useful for diagnosis. Rare antibodies have been described in CTDs in several case…
  • Abstract Number: 1109 • 2018 ACR/ARHP Annual Meeting

    Gene Expressions of TMEM176A and TMEM176B Were Prominent at the Stage of Subclinical Pulmonary Vascular Disease in Systemic Sclerosis

    Yoshinobu Koyama1, Soichiro Fuke2, Takashi Ohno3, Yoshiharu Sato4 and Toshie Higuchi1, 1Center for Autoimmune Diseases, Division of Rheumatology, Japan Red Cross Okayama Hospital, Okayama, Japan, 2Department of Cardiology, Japan Red Cross Okayama Hospital, Okayama, Japan, 3Management of medical safety, Okayama University Hospital, Okayama, Japan, 4DNA Chip Research Inc, Tokyo, Japan

    Background/Purpose: Pulmonary arterial hypertension (PAH) is prominent as a vascular involvement of systemic sclerosis (SSc), which remains a leading cause of death in spite of…
  • Abstract Number: 1113 • 2018 ACR/ARHP Annual Meeting

    Distinct Pathways in Anti-RNP-Associated Pulmonary Hypertension and Anti-RNP-Associated Raynaud’s Phenomenon

    Lisa Harlow1, Ying Wang2, YunJuan Zang2, Vineet Gupta3, Karen Young4, Jian Huang4, Bethly Aubourg2 and Eric Greidinger5, 1Rheumatology and Clinical Immunology, University of Miami Miller School of Medicine, Miami, FL, 2Rheumatology, University of Miami, Miami, FL, 3Rush University, Chicago, IL, 4Pediatrics, University of Miami, Miami, FL, 5Miami VA Medical Center, Miami, FL

    Background/Purpose: Anti-RNP Autoimmunity is associated with multiple manifestations of vasculopathy, including Raynaud’s Phenomenon (RP) and Pulmonary Hypertension (PH). We have previously linked anti-K10 antibodies to…
  • Abstract Number: 1123 • 2018 ACR/ARHP Annual Meeting

    Plasmacytoid Dendritic Cells in Bronchoalveolar Lavage Correlate with Pulmonary Artery Diameter and Infiltrate Perivascular Areas in the Lungs from Patients with Systemic Sclerosis Associated Pulmonary Hypertension

    Isela Valera1, Anagha Divekar2, Dinesh Khanna3, Fereidoun Abtin4, Rajan Saggar4 and Ram R. Singh4, 1Autoimmunity and Tolerance Laboratory, Division of Rheumatology, Department of Medicine, UCLA, Los Angeles, CA, 2Biolegend, Sa Diego, CA, 3Division of Rheumatology, Department of Internal Medicine, University of Michigan Scleroderma Program, University of Michigan, Ann Arbor, MI, 4UCLA, Los Angeles, CA

    Background/Purpose: In patients with systemic sclerosis (SSc), plasmacytoid dendritic cells (pDCs) increase in the bronchoalveolar lavage (BAL) and lung tissues (Kafaja S, et al, JCI…
  • Abstract Number: 1421 • 2018 ACR/ARHP Annual Meeting

    Evaluating the Validity of SIX-Minute Walk Test in Juvenile Systemic Sclerosis

    Oya Koker1, Amra Adrovic2, Sezgin Sahin2, Kenan Barut2, Rukiye Omeroglu3 and Ozgur Kasapcopur4, 1Istanbul University, Istanbul Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, 2Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, 3Pediatric Rheumatology, Istanbul University, Istanbul Medical School, Department of Pediatric Rheumatology, istanbul, Turkey, 4Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey

    Background/Purpose: Pulmonary vascular disease and interstitial lung fibrosis are the leading causes of morbidity and mortality in Juvenile Systemic Sclerosis (JSSc). Six-minute walk test (6MWT)…
  • Abstract Number: 1717 • 2018 ACR/ARHP Annual Meeting

    Expert Consensus on the Screening, Treatment, and Management of Patients with Systemic Sclerosis-Interstitial Lung Disease, and the Potential Role of Anti-Fibrotics in a Treatment Paradigm for Systemic Sclerosis-Interstitial Lung Disease: A Delphi Consensus Study

    Dinesh Khanna1,2, Mary Strek3, Brian Southern4, Rajan Saggar5, Vivien Hsu6, Maureen D. Mayes7, Rick Silver8, Virginia D. Steen9, Donald Zoz10 and Franck Rahaghi11, 1Division of Rheumatology, Department of Internal Medicine, University of Michigan Scleroderma Program, University of Michigan, Ann Arbor, MI, 2Division of Rheumatology, University of Michigan, Ann Arbor, MI, 3Pulmonology, University of Chicago, Chicago, IL, 4Pulmonology, Cleveland Clinic Ohio, Cleavland, OH, 5Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 6Rheumatology, Robert Wood Johnson University Scleroderma Program, New Brunswick, NJ, 7Rheumatology, University of Texas Medical School at Houston, Houston, TX, 8Rheumatology, Medical University of SC, Charleston, SC, 9Dept of Rheumatology, Georgetown Univ Medical Center, Washington, DC, 10Pulmonology, Boehringer Ingelheim, Ridgefield, CT, 11Cleveland Clinic Florida Weston, Weston, FL

    Background/Purpose: Systemic sclerosis (SSc), or scleroderma, is a rare, autoimmune, multisystem connective tissue disorder characterized by vascular damage, autoimmunity, and fibrosis of the skin and…
  • Abstract Number: 1721 • 2018 ACR/ARHP Annual Meeting

    Racial Differences in SSc Disease Presentation: A Cross-Sectional European Scleroderma Trials and Research Group Study

    Veronika K. Jaeger1, Elise Siegert2, Eric Hachulla3, Paolo Airò4, Gabriele Valentini5, Marco Matucci-Cerinic6, Oliver Distler7, Franco Cozzi8, Yannick Allanore9, Mangtao Li10, Mohammed Tikly11 and Ulrich A. Walker1, 1Department of Rheumatology, University Hospital Basel, Basel, Switzerland, 2Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, Berlin, Germany, 3Department of Internal Medicine and Clinical Immunology, Hôpital Claude Huriez, University of Lille, Lille, France, 4Rheumatology and Clinical immunology Unit, Spedali Civili of Brescia, Brescia, Italy, 5Second University of Naples, Naples, Italy, 6Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, 7Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 8Division of Rheumatology, Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, 9Immunogenetics, Cochin Institute, Paris, France, 10Peking Union Medical College Hospital, Beijing, China, 11Division of Rheumatology, Department of Internal Medicine, Chris Hani Baragwanath Hospital and University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose: Genetic and environmental factors play a significant role in SSc. African Americans are known for a higher SSc incidence, an earlier age of onset,…
  • Abstract Number: 1733 • 2018 ACR/ARHP Annual Meeting

    Should We Perform Exercise Echocardiogram As a Screening Test for Pulmonary Arterial Hypertension (PAH) for All Systemic Sclerosis (SSc) Patients?

    Luis Valdés1, Consuelo Orihuela-Sandoval2, Liliana Muñoz-Hernández3, Miguel Ayala-León2, José Luís Hernández-Oropeza4, Sergio Adán Benavides Suárez5, Alexia Esquinca-González5, Pablo Hernández-Reyes2 and Tatiana S. Rodriguez-Reyna5, 1Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán., Mexico City, Mexico, 2Cardiology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 3Endocrinology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 4Cardio-neumology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, 5Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico

    Background/Purpose: Prevalence of pulmonary arterial hypertension (PAH) in systemic sclerosis (SSc) is 8-12%, and 3-year survival rate is 47-56%. Rest echocardiogram is used to screen…
  • Abstract Number: 2214 • 2018 ACR/ARHP Annual Meeting

    Lung Involvement in Primary Sjögren’s Syndrome: Spectrum of Pulmonary Abnormalities and Computed Tomography Findings

    Janet Flores1, Diego Baenas2, Nadia Riscanevo3, Emanuel Saad4, Maria Jezabel Haye Salinas5, Soledad Retamozo6, Ana C. Alvarez5, Alejandro Alvarellos7, Juan Pablo Pirola8, Nadia Benzaquén5, Verónica Saurit9 and Francisco Caeiro8, 1Rheumatology Unit, Hospital privado Universitario de Córdoba, Cordoba, Argentina, 2Reumatologia, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina, 3Rheumatology, Rheumatology Unit, Hospital privado Universitario de Córdoba, Cordoba, Argentina, 4Internal medicine, Hospital Privado, Cordoba, Argentina, 5Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Córdoba, Argentina, 6Sociedad Argentina de Reumatologia, Córdoba, Argentina, 7Rheumatology, Rheumatology Unit, Hospital Privado Universitario de Córdoba, Cordoba, Argentina, 8Rheumatology, Hospital Privado Centro Médico de Córdoba, Córdoba, Argentina, 9Hospital Privado Centro Médico de Córdoba, Cordoba, Argentina

    Background/Purpose: Primary Sjögren's syndrome (pSS) is a chronic autoimmune disease that affects exocrine glands. It can generate pulmonary compromise due to dysfunction of the glandular…
  • Abstract Number: 2261 • 2018 ACR/ARHP Annual Meeting

    Long-Term Outcome of Pulmonary Sarcoidosis: A Population-Based Cohort Study from 1976-2013

    Patompong Ungprasert1,2, Cynthia S. Crowson3, Eva M. Carmona Porquera4 and Eric L. Matteson5, 1Clinical Epidemiology Unit, Department of Research and Development, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 2Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN, 3Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 4Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, MN, 5Division of Rheumatology, Mayo Clinic College of Medicine and Science, Rochester, MN

    Long-term Outcome of Pulmonary Sarcoidosis: A Population-Based Cohort Study from 1976-2013  Background/Purpose: A hallmark of sarcoidosis is lung disease, which has variable expression. This study…
  • Abstract Number: 2422 • 2018 ACR/ARHP Annual Meeting

    Pregnancy Outcomes in Patients with Interstitial Lung Disease Related to Autoimmune Disease and Sarcoidosis

    Stephanie L. Giattino, Amanda M. Eudy and Megan E. B. Clowse, Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC

    Background/Purpose: Currently published data regarding pregnancy outcomes in patients with interstitial lung disease (ILD) related to autoimmune disease and sarcoidosis is limited, with widely variant…
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