Abstracts tagged "Psoriatic arthritis"

Abstract Number: 0084 • ACR Convergence 2020
Clinical Characteristics of Patients with Rheumatism of Juvenile Onset and Adult Onset in the BIOBADAGUAY Cohort
Natalia Cabrera¹, Vannia Valinotti², Gabriela Avila-Pedretti¹, Sonia Cabrera², Patricia Melgarejo³, Zoilo Morel⁴, Lourdes Roman², Pedro Babak⁴, Rodrigo Acosta², Romina Glitz⁴, Darwin Cordovilla⁵, Roger Rolon⁴, Magali Zanotti-Cavazzoni¹, Marco Antonio Franco Britos⁶, Marcos Vazquez², Pedro Delgadillo⁴, Isabel Acosta², María del Carmen Martinez⁴, Gabriel Elizaur⁴, María Teresa Romero⁴, Ernesto Paredes⁴, Paloma de Abreu¹ and Leticia Segovia⁷, ¹Sociedad Paraguaya de Reumatología, Asunción, Paraguay, ²Hospital de Clínicas, Asunción, Paraguay, ³Hospital IPS, Villa Rica, Paraguay, ⁴Hospital Central del Instituto de Previsión Social, Asunción, Paraguay, ⁵Instituto Nacional de Reumatología, Montevideo, Uruguay, ⁶Instituto de Previsi�n Social, Asunci�n, Central, Paraguay, ⁷Hospital del IPS, Asunción, Paraguay
Background/Purpose: The Paraguayan-Uruguayan cohort of patients with rheumatic inflammatory diseases (BIOBADAGUAY), collect clinical and epidemiological information on adults and children patients receiving biological therapies (BT).…
Abstract Number: 0311 • ACR Convergence 2020
The Link Between Joints and Entheses in Psoriatic Arthritis: An Ultrasound Study Supporting the Synovio-entheseal Complex Theory
Gizem Ayan¹, Ilaria Tinazzi², Sibel Bakirci³, Ummugulsum Gazel⁴, Dilek Solmaz⁵, Umut Kalyoncu⁶ and Sibel Aydin⁷, ¹University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA, Ottawa Hospital Research Institute, OTTAWA, ON, Canada, ²Sacro Cuore Don Calabria Hospital, Unit of Rheumatology, Negrar-Verona, VR, ITALY, Verona, Italy, ³Antalya Research and Training Hospital, Antalya, TURKEY; University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA, Antalya, Turkey, ⁴University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA; The Ottawa Hospital Research Institute, Ottawa, ON, CANADA, ottawa, Canada, ⁵Izmir Katip Celebi University, Department of Internal Medicine, Division of Rheumatology, Izmir, TURKEY, Izmir, Turkey, ⁶Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ⁷University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, CANADA; The Ottawa Hospital Research Institute, Ottawa, ON, CANADA, Ottawa, ON, Canada
Background/Purpose: The aim of this study is to explore the link between the severity of the joint and entheses involvement in psoriatic arthritis (PsA) using…
Abstract Number: 0327 • ACR Convergence 2020
Skin Involvement in Psoriatic Arthritis (PsA) – The Incremental Impact of Psoriasis on Quality of Life, Disability and Work Productivity: Real-world Survey in US and Europe
Jessica Walsh¹, Alexis Ogdie², Kaleb Michaud³, Steven Peterson⁴, Elizabeth Holdsworth⁵, Sophie Meakin⁵, Soumya Chakravarty⁶, Nicola Booth⁵, Agata Schubert⁷, James Piercy⁵ and Laure Gossec⁸, ¹University of Utah School of Medicine, George E. Wahlen Veteran Affairs Medical Center, Salt Lake City, UT, ²Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ³University of Nebraska Medical Center, Omaha, NE, ⁴Janssen Immunology Global Commercial Strategy Organization, Horsham, PA, ⁵Adelphi Real World, Bollington, United Kingdom, ⁶Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, ⁷Janssen-Cilag, Janssen-Cilag, Poland, ⁸Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France
Background/Purpose: The degree of joint and skin involvement varies across patients with PsA. Differences in patient outcomes with active joint only vs. joint plus skin…
Abstract Number: 0345 • ACR Convergence 2020
Effectiveness and Safety of Apremilast in Biologic-Naive versus Biologic-Experienced Patients with Psoriatic Arthritis in Real-World Clinical Practice Settings in Germany: Interim Analysis of an Ongoing, Multicenter, Prospective, Non-interventional Study
Jurgen Wollenhaupt¹, Christian Bach² and Josefine Roemmler-Zehrer³, ¹Rheumatologie im Struenseehaus, Hamburg, Germany, ²Amgen GmbH, München, Germany, ³Amgen GmbH, München
Background/Purpose: Apremilast (APR) was associated with improvements in physician-assessed and patient-reported outcomes in a large cohort of patients with PsA based on a 1-year interim…
Abstract Number: 0372 • ACR Convergence 2020
Tumor Necrosis Factor-α Receptor 2 Polymorphisms and Response to TNF Inhibitor Therapy in Patients with Psoriatic Arthritis
Sarah Rasheed¹, MacKenzie Dunlap¹, Jennifer Harvey¹, Connery Brennan¹, Yuxuan Jin², Unnikrishnan Chandrasekharan³ and M. Elaine Husni², ¹Cleveland Clinic Foundation, Cleveland, ²Cleveland Clinic, Cleveland, OH, ³Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Tumor necrosis factor inhibitors (TNFi) have significantly improved the prognosis of patients with psoriatic arthritis (PsA); however, approximately 40% of patients do not achieve…
Abstract Number: 0507 • ACR Convergence 2020
Comparison of Secukinumab versus Adalimumab Efficacy by Sex in Psoriatic Arthritis from a Phase 3b, Double-blinded, Randomized, Active-controlled Study
Grace Wright¹, Peter Nash², Laura Coates³, Jordi Gratacós⁴, Frank Behrens⁵, Kevin Ding⁶, Weibin Bao⁷, Luminita Pricop⁶, Corine Gaillez⁸ and Iain McInnes⁹, ¹Association of Women in Rheumatology, New York, NY, ²School of Medicine Griffith University, Brisbane, Queensland, Australia, ³University of Oxford, Oxford, United Kingdom, ⁴University Hospital Parc Tauli Sabadell, Barcelona, Spain, ⁵CIRI/Rheumatology & Fraunhofer IME, Research Division Translational Medicine and Pharmacology, Goethe University Hospital, Frankfurt, Hessen, Germany, ⁶Novartis Pharmaceuticals Corporation, East Hanover, ⁷Novartis Pharmaceuticals Corporation, East Hannover, ⁸Novartis Pharma AG, Basel, Switzerland, ⁹Institute of Infection, Immunity, and Inflammation, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Lower efficacy to anti-tumor necrosis factor treatment has been reported in female patients with psoriatic arthritis (PsA) as compared to males in clinical registries.1…
Abstract Number: 0896 • ACR Convergence 2020
Impact of Upadacitinib on Reducing Pain in Patients with Active Psoriatic Arthritis: Results from Two Phase 3 Trials in Patients with Inadequate Response to Non-biologic or Biologic DMARDs
Iain McInnes¹, William Tillett², Philip Mease³, Kurt de Vlam⁴, Louis Bessette⁵, Ralph Lippe⁶, Anna Maniccia⁷, Patrick Zueger⁷, Dai Feng⁷, Koji Kato⁸ and Andrew Östör⁹, ¹Institute of Infection, Immunity, and Inflammation, University of Glasgow, Glasgow, United Kingdom, ²Royal National Hospital for Rheumatic Diseases, Bath, UK; Department of Pharmacy and Pharmacology, University of Bath, Bath, UK, Bath, United Kingdom, ³Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, ⁴Department of Rheumatology, University of Leuven, Belgium, Leuven, Belgium, ⁵Laval University, Quebec, Canada, ⁶AbbVie Deutschland GmbH & Co. KG, Wiesbaden, Germany, ⁷AbbVie Inc., North Chicago, IL, ⁸AbbVie Inc, North Chicago, IL, ⁹Cabrini Medical Center, Monash University, Malvern, Victoria, Australia
Background/Purpose: Pain is a dominant symptom of psoriatic arthritis (PsA), and pain reduction is a priority for patients (pts) that is often assessed in clinical…
Abstract Number: 1230 • ACR Convergence 2020
Curcumin: Prevalence and Perceived Efficacy in the Treatment of Rheumatoid and Psoriatic Arthritis
Neha Bhaskar¹, Lilian Otalora Rojas², Tara Jehu¹, Shazia Beg¹ and Neha Bhanusali¹, ¹University of Central Florida College of Medicine, orlando, ²University of Central Florida HCA Healthcare GME, Orlando
Background/Purpose: Ancient Eastern medicine has valued the Curcuma longa (turmeric) plant for its powerful medicinal properties. Curcumin is suggested to possess potent anti-inflammatory, antioxidant, antimicrobial,…
Abstract Number: 1349 • ACR Convergence 2020
Guselkumab Provides Domain-Specific and Comprehensive Efficacy as Assessed Using Composite Endpoints in Patients with Active Psoriatic Arthritis
Laura Coates¹, Christopher Ritchlin², Laure Gossec³, Philip Helliwell⁴, Proton Rahman⁵, Elizabeth Hsia⁶, Alexa Kollmeier⁷, Xie Xu⁸, Chetan Karyekar⁹, May Shawi¹⁰, Wim Noël¹¹, Yusang Jiang¹², Shihong Sheng¹², Prasheen Agarwal¹² and Philip Mease¹³, ¹University of Oxford, Oxford, United Kingdom, ²Department of Medicine, University of Rochester Medical Center, Rochester, NY, ³Sorbonne Université and Hôpital Universitaire Pitié Salpêtrière, Paris, France, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Memorial University of Newfoundland, Department of Medicine, St John's, Canada, ⁶Janssen Research & Development, LLC and University of Pennsylvania Medical Center, Spring House, PA, ⁷Janssen Research & Development, LLC, La Jolla, CA, ⁸Janssen Research & Development, LLC, San Marcos, CA, ⁹Janssen Global Services, LLC, Horsham, PA, ¹⁰Janssen Global Services, LLC, Toronto, ON, Canada, ¹¹Janssen Medical Affairs, LLC, Beerse, Belgium, ¹²Janssen Research & Development, LLC, Spring House, PA, ¹³Seattle Rheumatology Associates, P.L.L.C., Seattle, WA
Background/Purpose: Guselkumab (GUS) is a human monoclonal antibody that specifically binds to the p19-subunit of IL-23. GUS has demonstrated efficacy across the various manifestations of…
Abstract Number: 1476 • ACR Convergence 2020
Trends in Mortality and Cause-specific Mortality Among Patients with Psoriasis and Psoriatic Arthritis in Ontario, Canada
Keith Colaco¹, Jessica Widdifield², Jin Luo³, Cheryl Rosen⁴, Raed Alhusayen⁵, J. Michael Paterson⁶, Willemina Campbell⁷, Karen Tu⁴, Sasha Bernatsky⁸, Dafna Gladman⁹ and Lihi Eder¹⁰, ¹Institute of Medical Science, University of Toronto; Women's College Research Institute, Women's College Hospital; and Toronto Western Hospital, University Health Network, Toronto, ON, Canada, ²University of Toronto - Toronto, Toronto, ON, Canada, ³ICES, Toronto, Toronto, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada, ⁵Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada, ⁶ICES, University of Toronto, Toronto, ON, Canada, ⁷University Health Network, University of Toronto, Toronto, ON, Canada, ⁸The Research Institute of the McGill University Health Centre, Montreal, ON, Canada, ⁹Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, ¹⁰Women’s College Research Institute, University of Toronto, Toronto, ON, Canada
Background/Purpose: Several studies have consistently demonstrated that psoriasis is associated with an increased risk of mortality compared to the general population. However, the excess risk…
Abstract Number: 1860 • ACR Convergence 2020
An Integrative Approach to Identify Heritable and De Novo Genomic Variations in Psoriatic Arthritis Mutilans and Understand Its Systems Biology
Sara Rahmati¹, Quan Li¹, Dafna Gladman², Proton Rahman³ and Vinod Chandran², ¹University Health Network, Toronto, ON, Canada, ²Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, ³Memorial University of Newfoundland, Department of Medicine, St John's, Canada
Background/Purpose: Psoriasis is a chronic autoimmune skin disease that burdens ~3% of North Americans. ~24% of psoriatic patients develop psoriasis arthritis (PsA), an inflammatory disease…
Abstract Number: 0102 • ACR Convergence 2020
Bone Health in Patients with Psoriatic Arthritis in the National Swiss Cohort: A Cross-sectional Study
Diana Camelia Dan¹, Youssef Ibrahimy², Berengere Aubry-Rozier³ and Daniel Aeberli⁴, ¹Lausanne University Hospital, Lausanne, Switzerland, ²University of Lausanne, Lausanne, Switzerland, ³Hôpital orthopédique, Lausanne, Switzerland, ⁴University Hospital of Bern, Bern, Switzerland
Background/Purpose: There is much controversy surrounding the loss of bone mass in patients with psoriasis arthritis (PsA). We wanted to evaluate the prevalence of osteoporosis…
Abstract Number: 0312 • ACR Convergence 2020
Dactylitis Is Associated with Greater Disease Severity, Ultrasound Synovitis, and Erosive Damage, in Very Early DMARD Naïve Psoriatic Arthritis
Sayam Dubash¹, Oras Alabas², Xabier Michelena², Gabriele De Marco³, Leticia Garcia-Montoya², Richard Wakefield², Ai Lyn Tan², Philip Helliwell⁴, Paul Emery⁵, Dennis McGonagle² and Helena Marzo-Ortega², ¹The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Leeds, England, United Kingdom, ²The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Leeds, United Kingdom, ³The University of Leeds, Leeds Institute for Rheumatic and Musculoskeletal Medicine, NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals Trust, Leeds, UK, Treviglio, Italy, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom
Background/Purpose: Dactylitis is a hallmark feature of Psoriatic arthritis (PsA), defined as a uniform swelling of a finger or toe (“sausage digit”). It is associated…
Abstract Number: 0328 • ACR Convergence 2020
Healthcare Utilization and Costs Among Patients with Psoriatic Arthritis and Psoriasis in the United States – a Retrospective Study of Claims Data from 2009 to 2020
Joseph Merola¹, Reginald Villacorta², Natalie Dennis³, Soumya Chakravarty⁴, Laura Mesana⁵, Iris Lin², Maud Pacou³, Thomas Baker⁶, Yiting Wang⁷ and Steven Peterson⁸, ¹Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, ²Janssen Immunology Global Commercial Strategy Organization, Horsham, ³Amaris, Paris, France, ⁴Janssen Scientific Affairs, LLC, Horsham, PA, USA and Drexel University College of Medicine, Horsham, PA, ⁵Amaris, New York, ⁶Janssen Global Services, LLC, Raritan, NJ, ⁷Janssen R&D, LLC, Titusville, ⁸Janssen Immunology Global Commercial Strategy Organization, Horsham, PA
Background/Purpose: The costs of psoriasis and psoriatic arthritis (PsA) are substantial for both patients and the United States healthcare system. This study compared healthcare resource…
Abstract Number: 0346 • ACR Convergence 2020
Safety Profiles of Ixekizumab versus Adalimumab: 52-Week Results from a Head-to-Head Comparison in Patients with Active Psoriatic Arthritis
Philip Mease¹, Josef Smolen², Arthur Kavanaugh³, Peter Nash⁴, Gaia Gallo⁵, Soyi Liu-Leage⁵, Christophe Sapin⁵ and Mark Genovese⁶, ¹Seattle Rheumatology Associates, P.L.L.C., Seattle, WA, ²Division of Rheumatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria, ³UC San Diego Health System, San Diego, CA, ⁴School of Medicine Griffith University, Brisbane, Queensland, Australia, ⁵Eli Lilly and Company, Indianapolis, IN, ⁶Stanford University Medical Center, Palo Alto, CA
Background/Purpose: Ixekizumab (IXE) was shown to be superior to adalimumab (ADA) in achievement of simultaneous improvement of joint and skin disease (American college of Rheumatology…

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