Abstracts tagged "pregnancy"

Abstract Number: 1777 • ACR Convergence 2020
Low Dose Aspirin to Prevent Pre-eclampsia in SLE Pregnancies – Counselling Helps to Realize Our Full Potential
Isabell Haase¹, Matthias Schneider¹, Ralph Brinks¹ and Rebecca Fischer-Betz¹, ¹Department of Rheumatology and Hiller Research Unit Rheumatology, Heinrich Heine University, Duesseldorf, Germany, Duesseldorf, Germany
Background/Purpose: Women with Systemic Lupus Erythematosus (SLE) face a higher risk of pre-eclampsia, especially those with additional risk factors. Low dose aspirin (LDA) is known…
Abstract Number: 0247 • ACR Convergence 2020
Lupus Low Disease Activity State Achievement Is Important for Reducing Adverse Outcomes in Pregnant Patients with Systemic Lupus Erythematosus
Ji-Won Kim¹, Ju-Yang Jung¹, Hyoun-Ah Kim¹ and Chang-Hee Suh¹, ¹Ajou university school of medicine, Suwon, Republic of Korea
Background/Purpose: This study aimed to examine the frequency and risk factors of complications during pregnancy in women with systemic lupus erythematosus (SLE).Methods: The medical records…
Abstract Number: 1500 • ACR Convergence 2020
Electrocardiographic QT Intervals in Infants Exposed to Hydroxychloroquine Throughout Gestation
Deborah Friedman¹, Mimi Kim², Nathalie Costedoat-Chalumeau³, Robert Clancy⁴, Joshua Copel⁵, Colin Phoon⁶, Bettina Cuneo⁷, Rebecca Cohen⁶, Mala Masson⁶, Benjamin Wainwright⁶, Noel Zahr⁸, Amit Saxena⁴, Peter Izmirly⁹ and Jill Buyon¹⁰, ¹New York Medical College, Valhalla, ²Albert Einstein College of Medicine, Bronx, ³APHP, Université de Paris, Paris, France, ⁴NYU School of Medicine, New York, ⁵Yale School of Medicine, New Haven, ⁶New York University School of Medicine, New York, ⁷University of Colorado School of Medicine, Aurora, ⁸Pitié-Salpêtrière University Hospital, Paris, France, ⁹Department of Medicine, New York University School of Medicine, New York, NY, ¹⁰Department of Medicine, NYU School of Medicine, New York, NY
Background/Purpose: Based on inhibition of viral replication and limited reports on clinical efficacy, hydroxychloroquine (HCQ) was initially considered as a prophylaxis and treatment of COVID-19. …
Abstract Number: 1780 • ACR Convergence 2020
Maternal and Fetal Outcomes in Pregnant Women with Psoriatic Arthritis: A Systematic Literature Review
Agna Neto¹, Rita Pinheiro Torres², Helena Donato³, Ana Filipa Mourão², Jaime Branco² and Fernando Pimentel-Santos⁴, ¹1. Rheumatology Department, Hospital Central do Funchal, Madeira, Portugal. 2. Hospital de Egas Moniz, CHLO, Lisbon, Portugal. 3. CEDOC, NOVA Medical School, Lisbon, Portugal, Lisbon, Portugal, ²2. Hospital de Egas Moniz, CHLO, Lisbon, Portugal. 3. CEDOC, NOVA Medical School, Lisbon, Portugal, Lisbon, Portugal, ³4. Serviço de Documentação, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Coimbra, Portugal, ⁴3.CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal; 7.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisbon, Portugal
Background/Purpose: The onset of psoriatic arthritis (PsA) often occurs between the ages of 30 and 50 years. Accordingly, many female patients are diagnosed during childbearing…
Abstract Number: 0262 • ACR Convergence 2020
SLE Pregnancies: C4 as Predictor of Flares and Adverse Pregnancy Outcomes
Francesca Crisafulli¹, Laura Andreoli¹, Matteo Filippini¹, Micaela Fredi¹, Maria Chiara Gerardi¹, Roberto Gorla², Maria Grazia Lazzaroni¹, Daniele Lini¹, Cecilia Nalli², Marco Taglietti¹, Andrea Lojacono³, Sonia Zatti³, Cristina Zanardini³, Franco Franceschini¹ and Angela Tincani¹, ¹Rheumatology and Clinical Immunology Unit, Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, ²Rheumatology and Clinical Immunology Unit, ASST Spedali Civili of Brescia, Brescia, Lombardia, Italy, ³Obstetrics and Gynecology Unit, Spedali Civili and University of Brescia, Brescia, Lombardia, Italy
Background/Purpose: SLE pregnancies have an increased risk of Adverse Pregnancy Outcomes (APO). In clinical practice, low C3 and C4 levels are associated with active disease…
Abstract Number: 1501 • ACR Convergence 2020
Obstetrical Outcome and Thromboses in a Multicentric Cohort of Antiphospholipid Syndrome (APS) Patients with Severe Preeclampsia: An Analysis of APS Classification Criteria
Maddalena Larosa¹, Nathalie Morel², Meriem Belhocine³, Amelia Ruffatti⁴, Nicolas Martin Silva⁵, Romain Paule⁶, Luc Mouthon⁷, Michel Dreyfus⁸, Jean-Charles Piette⁹, Odile Souchaud-Debouverie¹⁰, Catherine Deneux-Tharaux¹¹, Vassilis Tsatsaris¹², Emmanuelle Pannier Metzger¹³, Gaëlle Guettrot-Imbert¹⁴, Veronique Le Guern¹⁵, Andrea Doria¹⁶ and Nathalie Costedoat-Chalumeau¹⁷, ¹Rheumatology Unit-Department of Medicine-University of Padova, Italy, Padova, Veneto, Italy, ²AP-HP, université René-Descartes Paris V, hôpital Cochin, centre de référence maladies auto-immunes et systémiques rares, pôle médecine, service de médecine interne, Paris, France., Paris, Ile-de-France, France, ³Hôpital Sacré-Coeur de Montréal , Montréal, Montreal, QC, Canada, ⁴Department of Medicine, University of Padova, Padova, Veneto, Italy, ⁵Centre Hospitalier et Universitaire de Caen, Caen, France, ⁶Foch Hospital, Paris, France, ⁷Hopital Cochin - Paris University, Paris, France, ⁸CHU de Caen, Caen, France, ⁹Department of Internal Medicine, Hôpital Pitié-Salpêtrière, Paris, France, Paris, France, ¹⁰CENTRE HOSPITALIER UNIVERSITAIRE LA MILETRIE, poitiers, France, ¹¹INSERM U1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team, Center for Epidemiology and Statistics Sorbonne Paris Cité , Paris Descartes University , Paris , France, Paris, France, ¹²Maternité Port-Royal,Hôpital Cochin, Paris, France, Paris, France, ¹³Maternité Port-Royal,Hôpital Cochin, Paris, France, ¹⁴Médecine Interne,Hôpital Cochin, paris, France, ¹⁵Médecine Interne,Hôpital Cochin, Paris, France, Paris, France, ¹⁶University of Padua, Padua, Italy, ¹⁷APHP, Université de Paris, Paris, France
Background/Purpose: According to APS classification criteria1, clinical manifestations of antiphospholipid syndrome (APS) consist in thrombotic and obstetric events, including severe preeclampsia (PE). Because little is…
Abstract Number: 1781 • ACR Convergence 2020
Pregnancy After Bariatric Surgery in Women with Rheumatic Diseases and Association with Adverse Birth Outcomes
Namrata Singh¹, Rebecca Baer², Maya Swaminathan³, Shireesh Saurabh⁴, Jeffrey Sparks⁵, Gretchen Bandoli⁶, Elena Flowers⁷, Laura Jelliffe-Pawlowski² and Kelli Ryckman⁸, ¹University of Washington, Bellevue, WA, ²University of California San Francisco, San Francisco, ³University of Washington, Seattle, WA, ⁴Kaiser Permanente WA, Bellevue, WA, ⁵Brigham and Women's Hospital, Boston, MA, ⁶University of California San Diego, La Jolla, CA, ⁷UCSF, San Francisco, CA, ⁸University of Iowa, Iowa City
Background/Purpose: Autoimmune rheumatic diseases (ARD) and bariatric surgery are each risk factors for adverse birth outcomes. To date, no study has investigated their combined impact…
Abstract Number: 0266 • ACR Convergence 2020
The Correlation Between Pregnancy, Disease Activity and Adverse Pregnancy Outcomesin Patients with Systemic Lupus Erythematosus
Cigdem Cetin¹, Tugba Sarac Sivrikoz¹, Muge Ates Tıkız¹, Ege Sinan Torun¹, Sibel Zarali¹, Yasemin Yalcinkaya¹, Ahmet Gül¹, Murat İnanç¹, Mahdume Lale Öcal², İbrahim Kalelioğlu¹ and Bahar Artim Esen¹, ¹İstanbul Faculty of Medicine, İstanbul, Turkey, ²Department of Rheumatology, Istanbul Faculty of Medicine, Istanbul University, İstanbul, Turkey
Background/Purpose: Patients with systemic lupus erythematosus (SLE) can present with acute disease flares/exacerbations during pregnancy and postpartum period1. These flares can cause adverse pregnancy outcomes…
Abstract Number: 1611 • ACR Convergence 2020
Documentation of Pregnancy Counseling in SSA-Positive Patients of Childbearing Potential: A Cross-Sectional Study
Heinrich-Karl Greenblatt¹ and Elena Weinstein¹, ¹University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Systemic lupus erythematosus (SLE) and primary Sjogren's Syndrome (SS) are highly associated with anti-SSA (anti-Ro) seropositivity. Anti-SSA autoantibodies may cross the placenta, causing a…
Abstract Number: 1782 • ACR Convergence 2020
Use of a Patient-reported Survey to Document Contraceptive Use and Interest in Pregnancy to Identify Patients with Unmet Pregnancy Prevention and Planning Needs
Megan Clowse¹, Amanda Eudy², Lisa Criscione-Schreiber³, Jayanth Doss², Kai Sun², Rebecca Sadun² and Jennifer Rogers⁴, ¹Duke University, Chapel Hill, NC, ²Duke University, Durham, NC, ³Duke University School of Medicine, Durham, NC, ⁴Duke, Durham, NC
Background/Purpose: Pregnancies in women with lupus who conceive when their disease is active or they are taking a teratogen are at increased risk for pregnancy…
Abstract Number: 0382 • ACR Convergence 2020
Increased Rates of Obstetric Complications Prior to Systemic Sclerosis Diagnosis
Melody Chung¹, Kathleen Kolstad², Makdine Dontsi³, Poonam Manwani⁴, Hongyu Zhao⁵, Debbie Postlethwaite³, Sumana Kesh⁶, Julia Simard⁷ and Lorinda Chung⁸, ¹Stanford University, Stanford, CA, ²Division of Immunology & Rheumatology, Stanford University School of Medicine, Palo Alto, CA, ³Division of Research, Kaiser Permanente Northern California, Oakland, CA, ⁴UCLA-Olive View Rheumatology Fellowship, Los Angeles, CA, ⁵Department of Internal Medicine, Kaiser Permanente Santa Clara, Santa Clara, CA, ⁶Kaiser Permanente Santa Clara, Santa Clara, CA, ⁷Stanford Medicine, Stanford, CA, ⁸Stanford University School of Medicine and Palo Alto VA Health Care System, Palo Alto, CA
Background/Purpose: Vasculopathy and immune dysfunction likely precede the diagnosis of systemic sclerosis (SSc) by years as evidenced by longstanding Raynaud’s phenomenon prior to diagnosis. Poor…
Abstract Number: 1765 • ACR Convergence 2020
Obstetric Outcomes in Younger Women Less Than 21 Years of Age Compared to Women Between Age 21 and 25 Years with Rheumatic Disease
Chelsey Smith¹, Christina Chambers¹, Rebecca Baer², Laura Jelliffe-Pawlowski³ and Gretchen Bandoli¹, ¹University of California San Diego, La Jolla, CA, ²University of California San Diego, La Jolla, ³University of California San Francisco, San Francisco
Background/Purpose: Very young maternal age has been described as a risk factor for several adverse obstetric outcomes. This study aimed to investigate whether younger women…
Abstract Number: 1783 • ACR Convergence 2020
Experience of Pregnant Rheumatology Outpatients from a Tertiary Hospital in New York City During the COVID-19 Pandemic
Bessie Stamm¹, Gregory Vitone², Marianna Frey³, JoAnn Vega¹, Jane Salmon³, Mary Crow³, Vivian Bykerk³, Michael Lockshin¹, Lisa Sammaritano¹, Lisa Mandl³ and Medha Barbhaiya¹, ¹Hospital for Special Surgery, Barbara Volcker Center for Women and Rheumatic Diseases, New York, NY, ²Hospital for Special Surgery, New York, ³Hospital for Special Surgery, New York, NY
Background/Purpose: We aimed to evaluate the experience of pregnant rheumatology patients during the peak of the COVID-19 pandemic in New York City.Methods: We emailed a…
Abstract Number: 1938 • 2019 ACR/ARP Annual Meeting
The Pre-pregnancy Rheumatoid Arthritis Gene Expression Signature Correlates with Improvement or Worsening of Disease Activity During Pregnancy: A Pilot Study
Amogh Pathi ¹, Mette Smed ², Lior Pachter ³, Elizabeth Purdom ⁴, Matthew Wright ⁵, Nicholas Jewell ⁴, J. Lee Nelson ⁶, Jørn Olsen ⁷, Merete Lund Hetland ⁸, Vibeke Zoffmann ⁹ and Damini Jawaheer¹⁰, ¹UCSF Benioff Children's Hospital Oakland, Oakland, ²Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark, ³Caltech, Pasadena, ⁴University of California Berkeley, Berkeley, ⁵UCSF Benioff Children's Hopsital Oakland, Oakland, ⁶Fred Hutchinson Cancer Research Center, Seattle, ⁷Aarhus University Hospital, Aarhus, Denmark, ⁸DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, ⁹Juliane Marie Center, Copenhagen University Hospital, Rigshospitalet, Copenhagen, ¹⁰UCSF Benioff Children's Hospital Oakland, Oakland, CA
Background/Purpose: Pregnancy is known to induce a natural improvement of Rheumatoid Arthritis (RA) symptoms in 50-75% of patients as gestation progresses. However, the underlying mechanisms…
Abstract Number: 2273 • 2019 ACR/ARP Annual Meeting
Risk of Serious Infections in Offspring According to TNFi Subtypes
Evelyne Vinet¹, Yvan St-Pierre ¹, Cristiano S. Moura ¹, Jeffrey Curtis ² and Sasha Bernatsky ³, ¹McGill University Health Centre, Montreal, QC, Canada, ²University of Alabama at Birmingham, Birmingham, AL, ³Research Institute of the McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: TNFi subtypes have differential placental transfer, with some reaching higher fetal than maternal blood levels. Thus, certain TNFi subtypes could cause immunosuppression in the offspring.…

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