Abstracts tagged "Pediatric rheumatology"

Abstract Number: 0412 • ACR Convergence 2024
Impact of Approval of Biologic DMARDs on JIA Outcomes in a Single Center
Anna Sutton¹, Erin Balay-Dustrude¹, Beth A Mueller¹ and Susan Shenoi², ¹University of Washington, Seattle, WA, ²Seattle Children's Hospital and Research Center, Mercer Island, WA, WA
Background/Purpose: In clinical trials, biologic disease-modifying antirheumatic drugs (bDMARDs) for juvenile idiopathic arthritis (JIA) have demonstrated good efficacy. However, less is known about the impact…
Abstract Number: 1258 • ACR Convergence 2024
Investigating Factors Associated with Gaps in Care in Adolescents and Young Adults with Systemic Lupus
Tamar Rubinstein¹, Avni Dave², Terrence Calistro³, Kimberly Rapoza³, Joyce Hui-Yuen⁴, Emily Masi⁵, Shari Salzhauer Berkowitz³, Zanab Mian⁶ and Kathleen Kenney-Riley⁷, ¹Albert Einstein College of Medicine, White Plains, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Mercy University, Dobbs Ferry, NY, ⁴North Shore LIJ Health System, Great Neck, NY, ⁵Cohen Children's Medical Center, Floral Park, NY, ⁶Cohen Children's Medical Center, Lake Success, NY, ⁷Albert Einstein College of Medicine, Port Chester, NY
Background/Purpose: Adolescents and young adults (AYA) with systemic lupus (SLE) are at an especially high risk for disengagement in care, a possible cause of the…
Abstract Number: 1275 • ACR Convergence 2024
Implementing Integrated Mental Health Care in a Juvenile Myositis Clinic: A One-Year Review
Luana Flores Pereira¹, Louise Boulard², Kayla M. Baker³, Audrey Bell-Peter⁴, Vanessa Carbone³, Brian Feldman⁵, Jayne MacMahon⁶, Valerio Maniscalco⁷, Jo-Anne Marcuz⁸, Tanya Slater⁴, Kristi Whitney⁴, Y. Ingrid Goh³ and Andrea Knight⁹, ¹Neurosciences and Mental Health Program, SickKids Research Institute, Toronto, ON, Canada, ²Neurosciences and Mental Health Program, SickKids Research Institute; The Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ³Division of Rheumatology, The Hospital for Sick Children; Child Health Evaluative Sciences, SickKids Research Institute, Toronto, ON, Canada, ⁴Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁵Division of Rheumatology, The Hospital for Sick Children; Departments of Pediatrics and Medicine, Faculty of Medicine; The Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ⁶Division of Rheumatology, The Hospital for Sick Children; Department of Pediatrics, Temerty Faculty of Medicine, University of Toronto; Child Health Evaluative Sciences, SickKids Research Institute, Toronto, ON, Canada, ⁷Rheumatology Unit, ERN-ReCONNET Center, Meyer Children Hospital IRCCS; Department of Pediatrics, Santo Stefano Hospital, Florence, Italy, ⁸Division on Rheumatology, The Hospital for Sick Children; Department of Rehabilitation Services, The Hospital for Sick Children, Toronto, ON, Canada, ⁹Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada
Background/Purpose: Juvenile myositis (JM) patients experience a high burden of emotional distress, yet mental health (MH) care is not typically integrated into standard clinical practices.…
Abstract Number: 1739 • ACR Convergence 2024
Adult and Pediatric Rheumatology Fellow Education on Temporomandibular Joint (TMJ) Arthritis in Patients with Juvenile Idiopathic Arthritis
Sarah Bayefsky¹, Meghan Ryan², Nancy Pan³, Tova Ronis⁴, Marinka Twilt⁵, Melissa Lerman⁶ and CARRA TMJ Workgroup⁷, ¹University of Pennsylvania/Children's Hospital of Philadelphia, PHILADELPHIA, PA, ²Unity Point - Blank Children's Hospital, Booneville, IA, ³Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ⁴Children's National Hospital, Washington, DC, ⁵Alberta Children's Hospital, Calgary, AB, Canada, ⁶Children's Hospital of Philadelphia, Philadelphia, PA, ⁷CARRA, Washington, DC
Background/Purpose: Arthritis of the temporomandibular joint, or TMJ arthritis, is an underrecognized manifestation of juvenile idiopathic arthritis (JIA). The absence of prompt treatment may lead…
Abstract Number: 1792 • ACR Convergence 2024
CD14+ Monocytes Demonstrate Subclinical Erythrocyte Uptake in Childhood Onset Systemic Lupus Erythematosus
Lauren Robinson¹, Preetha Balasubramanian², Zurong Wan², Juan Rodriguez Alcazar², Marina Lima Silva Santos², Lynnette Walters³, Jeanine Baisch², Karen Onel⁴, Tracey Wright⁵, Virginia Pascual⁶ and Simone Caielli², ¹Hospital for Special Surgery, New York, NY, ²Weill Cornell Medicine, New York, NY, ³Scottish Rite Hospital for Children, Allen, TX, ⁴HSS, New York, NY, ⁵UT Southwestern, Plano, TX, ⁶Weill Cornell Medical College, New York, NY
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a disease characterized by the presence of auto-antibodies, immune complex deposition, and a robust type I interferon (IFN) signature.…
Abstract Number: 2176 • ACR Convergence 2024
Applying Similarity Network Fusion to Identify Patient Clusters for People with Systemic Inflammatory Disease
Nicholas C Chan¹, Anika Rueppell², Daniela Dominguez³, Tom Appleton⁴, Michelle Batthish⁵, Roberta A Berard⁶, Tania Cellucci⁵, Erkan Demirkaya⁷, Michelle Diebold⁶, Liane Heale⁸, Peter Kannu⁹, Deborah Levy¹⁰, Jonathan Park¹¹, Jean-Philippe Proulx-Gauthier¹², Angela Punnett¹⁰, Johannes Roth¹³, Rayfel Schneider¹⁴, Lynn Spiegel¹⁵, Rae Yeung¹⁶, Jason An¹, Anjali Jain³, Madeline Couse¹⁰, Dilan Dissanayake¹⁰, Ronald Laxer², Lauren Erdman¹⁰ and Linda Hiraki¹⁰, ¹University of Toronto, Toronto, ON, Canada, ²SickKids, Toronto, ON, Canada, ³The Hospital for Sick Children, Toronto, Canada, ⁴The University of Western Ontario, London, ON, Canada, ⁵McMaster Children's Hospital, Hamilton, ON, Canada, ⁶London Health Sciences Centre, London, ON, Canada, ⁷Victoria Hospital & Children's Hospital, Toronto, ON, Canada, ⁸McMaster University, Oakville, ON, Canada, ⁹University of Alberta, Edmonton, AB, Canada, ¹⁰The Hospital for Sick Children, Toronto, ON, Canada, ¹¹London Health Sciences Centre Victoria Hospital, Lodon, Canada, ¹²l'Université Laval, Quebec City, QC, Canada, ¹³Cantonal Hospital Luzern and Children's Hospital of Central Switzerland, Luzern, Switzerland, ¹⁴The Hospital for Sick Children, Toronto, Ontario, Canada, Toronto, ON, Canada, ¹⁵University of Toronto/Hospital for Sick Children, Toronto, ON, Canada, ¹⁶The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada
Background/Purpose: Systemic inflammatory diseases (SIDs) are characterized by non-infectious multisystem inflammation. Genetic panels only diagnose 25% of suspected SID patients, due to the clinical and…
Abstract Number: 2200 • ACR Convergence 2024
Whole Blood Transcriptome Profiling in Juvenile Systemic Sclerosis Patients Reveals Active Immune Upregulation and Enhanced Fibrotic Signature
Rania Elbakri¹, Amanda Robinson², Anwesha Sanyal¹ and Kathryn Torok³, ¹University of Pittsburgh, pittsburgh, PA, ²University of Utah Health, Salt Lake City, UT, ³Division of Rheumatology, Scleroderma Center, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA
Background/Purpose: Juvenile systemic sclerosis (jSSc) is a rare chronic autoimmune disorder characterized by skin thickening and multisystem organ involvement, leading to significant morbidity. The pathogenesis…
Abstract Number: 2570 • ACR Convergence 2024
Comparison of the Clinical Features and Biomarker Profiles of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Systemic Juvenile Idiopathic Arthritis- Associated Lung Disease (SJIA-LD) Cohort to CARRA Registry SJIA Patients Without Lung Disease
Esraa Eloseily¹, Autumn Clark¹, Min-Lee Chang², Mary Ellen Riordan³, Alan Russell⁴, Marc Natter⁵, Scott Canna⁶, Sherry Thornton⁷, Yukiko Kimura⁸ and grant schulert¹, and CARRA FROST Investigators and the CARRA Registry SJIA-LD Cohort Investigators, ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Computational Health Informatics Program, Boston Children’s Hospital, Boston, MA, ³Hackensack University Medical Center, Westwood, NJ, ⁴Duke Clinical Research Institute, Durham, NC, ⁵Boston Children's Hospital, Boston, MA, ⁶Children's Hospital of Philadelphia, Philadelphia, PA, ⁷Cincinnati Children's Hospital, Cincinnati, ⁸Hackensack Meridian School of Medicine, New York, NY
Background/Purpose: Systemic juvenile idiopathic arthritis (SJIA) associated lung disease (SJIA-LD) is an emerging life-threatening disease with urgent unmet knowledge gaps. This study compares the clinical…
Abstract Number: 0389 • ACR Convergence 2024
Histopathological Features of Liver Tissue Biopsies in SJIA Patients with and Without Clinical Macrophage Activation Syndrome
Esraa Eloseily¹, Lara Berklite², Jennifer Picarsic¹, grant schulert¹, Rachel Sheridan¹ and Alexei Grom¹, ¹Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Cincinnati Children's Hospital Medical Center, Cincinnti, OH
Background/Purpose: Systemic Juvenile Idiopathic Arthritis (SJIA) can present with or without Macrophage Activation Syndrome (MAS), a severe, potentially life-threatening complication. Liver tissue injury is commonly…
Abstract Number: 0414 • ACR Convergence 2024
Relationship Between Culture Negative Infectious Osteomyelitis and Chronic Nonbacterial Osteomyelitis
Andrew Grim¹, Yongdong (Dan) Zhao², Christine Wang¹, Erin Janssen³, Jessica Turnier⁴, Anastasia Hyrhorczuk¹ and Nadine Saad¹, ¹University of Michigan, Ann Arbor, MI, ²University of Washington, Redmond, WA, ³CS Mott Children's Hospital, Ann Arbor, MI, ⁴University of Michigan, Saline, MI
Background/Purpose: Chronic nonbacterial osteomyelitis (CNO) is a rare autoinflammatory bone disorder. Some patients with CNO may present acutely and be misdiagnosed as infectious osteomyelitis (IO).…
Abstract Number: 1259 • ACR Convergence 2024
Adverse Childhood Experiences Are Associated with Patient-Reported Outcomes in Adolescents and Young Adults with Systemic Lupus
Tamar Rubinstein¹, Avni Dave², Terrence Calistro³, Kimberly Rapoza³, Shari Salzhauer Berkowitz³, Joyce Hui-Yuen⁴, Zanab Mian⁵, Emily Masi⁶ and Kathleen Kenney-Riley⁷, ¹Albert Einstein College of Medicine, White Plains, NY, ²Albert Einstein College of Medicine, Bronx, NY, ³Mercy University, Dobbs Ferry, NY, ⁴Northwell Health, Cohen Children's Medical Center, Great Neck, NY, ⁵Cohen Children's Medical Center, Lake Success, NY, ⁶Cohen Children's Medical Center, Floral Park, NY, ⁷Albert Einstein College of Medicine, Port Chester, NY
Background/Purpose: Adverse childhood experiences (ACEs), are major life stressors that occur before the age of 18 and include experiences of household dysfunction. Recently, prior trauma,…
Abstract Number: 1276 • ACR Convergence 2024
Therapeutic Drug Monitoring (TDM) of Rituximab to Predict Early B-Cell Repopulation in Children
Rana Alsulami¹, Bindiya Chugani², Joley Johnstone², Ann Yeh², Floris Loeff³, Linda Hiraki², Andrea Knight⁴, Deborah Levy² and Ruud Verstegen², ¹University of Toronto, Toronto, ON, Canada, ²The Hospital for Sick Children, Toronto, ON, Canada, ³Sanquin Diagnostic Services, Amsterdam, Netherlands, ⁴Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada
Background/Purpose: Rituximab is increasingly used in pediatric inflammatory diseases, with dosing extrapolated from adult data due to a lack of pediatric-specific pharmacokinetic (PK) information. Children…
Abstract Number: 1742 • ACR Convergence 2024
Multi-Center Use of an Online Case-Based Simulation to Educate Pediatric Trainees on Musculoskeletal Complaints and High-Value Care
Marina Latif¹, Kyla Driest², Erin Frank³, Allayne Stephans³, Stacey Tarvin⁴ and Angela Robinson⁵, ¹Case Western Reserve University School of Medicine, Cleveland, OH, ²Nationwide Children's Hospital, Columbus, OH, ³Rainbow Babies and Children's Hospital, Cleveland, OH, ⁴Indiana University School of Medicine, Indianapolis, IN, ⁵Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Excessive healthcare spending in the United States remains a growing concern, and teaching high-value care is essential to combat wasted costs. It is…
Abstract Number: 1794 • ACR Convergence 2024
Biobehavioral Basis and Outcomes of Cognitive Dysfunction in Childhood Systemic Lupus Erythematosus
Hanne van der Heijden¹, Andrea Knight², Itamar Ronen³, Gabrielle Alonzi⁴, Kyle McBrearty⁴, Aditi Deokar⁴, Joseph Gonzalez-Heydrich⁴, Joyce Chang⁴ and Jaymin Upadhyay⁵, ¹Boston Children's Hospital Harvard Medical School, Boston, MA, ²Division of Rheumatology, The Hospital for Sick Children; Neurosciences and Mental Health, SickKids Research Institute; Department of Paediatrics, University of Toronto, Toronto, ON, Canada, ³Brighton and Sussex Medical School, University of Sussex, Brighton, UK, Brighton, United Kingdom, ⁴Boston Children's Hospital, Boston, MA, ⁵Boston Children's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Cognitive dysfunction (CD) in childhood-onset SLE (cSLE) is undertreated yet profoundly impacts lifelong health-related quality of life. Investigating CD in cSLE is crucial, given…
Abstract Number: 2179 • ACR Convergence 2024
Evaluation of Diagnostic Concordance Between Telehealth Encounters and In-Person Follow-up Assessments in Pediatric Rheumatology
Laura Aisenberg¹, Irit Rasooly¹, Pamela Weiss², Jon Burnham³ and Anna Costello¹, ¹Children's Hospital of Philadelphia, Philadelphia, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³Children's Hospital of Philadelphia, Bryn Mawr, PA
Background/Purpose: In early 2020, much of the country’s pediatric rheumatology practice shifted to a telehealth model secondary to the SARS-CoV-2 pandemic. During this discrete period,…

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