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Abstracts tagged "Pediatric rheumatology"

  • Abstract Number: 0171 • ACR Convergence 2020

    Interferon Response Gene Expression Differs in Whole Blood, Peripheral Blood Mononuclear Cells, Monocytes, T Cells, B Cells, and NK Cells in Patients with the Autoinflammatory Interferonopathies, CANDLE and SAVI

    Jacob Mitchell1, Sara Alehashemi2, Bernadette Marrero3, Yan Huang4, Sofia Torreggiani1, Lena Bichell1, Gina Montealegre Sanchez5, Raphaela Goldbach-Mansky6 and Adriana de Jesus7, 1Translational Autoinflammatory Disease Section (TADS)/NIAID/NIH, Bethesda, MD, 2Translational Autoinflammatory Disease Section (TADS)/NIAID/NIH, Clarksville, MD, 3Computational Systems Biology Section/NIAID/NIH, Bethesda, MD, 4NIH, Bethesda, 5NIAID/NIH, Rockville, MD, 6Translational Autoinflammatory Disease Section (TADS)/NIAID/NIH, Potomac, MD, 7Translational Autoinflammatory Disease Section (TADS)/NIAID/NIH, Silver Spring, MD

    Background/Purpose: The disease progression of patients (pts.) with type-I interferon (IFN)-mediated diseases undergoing treatment with JAK1 and JAK2 inhibitors is monitored in part by measuring…
  • Abstract Number: 0721 • ACR Convergence 2020

    Validation of New Antirheumatic Drug Use as a Proxy for Increased JIA Disease Activity

    Avinash Gabbeta1, Evan Mulvihill2, Timothy Beukelman3, James Lewis4, Carlos Rose5, Brian Strom6 and Daniel Horton7, 1St. Christopher's Hospital for Children, Philadelphia, PA, 2Nemours A.I. duPont Hospital for Children, Wilmington, DE, 3University of Alabama at Birmingham, Birmingham, AL, 4University of Pennsylvania, Philadelphia, PA, 5Nemours A.I. duPont Hospital for Children, Wilmingon, DE, 6Rutgers University, Newark, NJ, 7Rutgers University, New Brunswick, NJ

    Background/Purpose: Administrative claims databases are valuable tools for studying treatment effects in large JIA populations but do not contain direct measures of disease activity, limiting…
  • Abstract Number: 1142 • ACR Convergence 2020

    Implementation of an Evidence-based Transition Clinic in a Pediatric Rheumatology Academic Institution

    Rebecca Overbury1, Tracy Frech2, John Bohnsack3, CJ Inman1, Sara Stern1, Karen James1, Erin Treemarcki4 and Aimee Hersh4, 1University of Utah and Primary Children's Hospital, Salt Lake City, UT, 2University of Utah and Salt Lake Veterans Affair Medical Center, Salt Lake City, UT, 3University of Utah and Primary Children's Hospital, Cincinnati, OH, 4University of Utah and Primary Children's Hospital, Salt Lake City

    Background/Purpose: Transition from pediatric to adult rheumatology care is more likely to be successful if a transition program is in place. Previously successful interventions to…
  • Abstract Number: 1175 • ACR Convergence 2020

    Using a Patient-Engaged Approach to Identify Cross-Cutting Disease Factors Impacting Mental Health in Youth with Rheumatologic Disease

    Ashley Danguecan1, Oluwatunmise Fawole2, Michelle Reed3, Julia Harris4, Aimee Hersh5, Martha Rodriguez6, Karen Onel7, Erica Lawson8, Tamar Rubinstein9, Kaveh Ardalan10, Esi Morgan11, Anne Paul12, Judy Barlin13, R. Paola Daly14, Mitali Dave15, Shannon Malloy16, Shari Hume15, Suzanne Schrandt17, Laura Marrow18, Angela Chapson3, Donna Napoli3, Michael Napoli3, Miranda Moyer3, Vincent Delgaizo19, Emily von Scheven8 and Andrea Knight20, 1Hospital for Sick Children, Toronto, Canada, 2New York University School of Medicine, New York, 3Children's Hospital of Philadelphia, Philadelphia, 4Children's Mercy Kansas City, Overland Park, KS, 5University of Utah and Primary Children's Hospital, Salt Lake City, 6Riley Hospital for Children at Indiana University Health, Indianapolis, 7Pediatric Rheumatology, Hospital for Special Surgery, New York, NY, 8University of California San Francisco, San Francisco, 9Albert Einstein College of Medicine / Montefiore Medical Center, White Plains, NY, 10Duke University Medical Center, Durham, NC, 11Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 12Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, 13Lupus Foundation of America, Miami, 14Lupus Foundation of America, Washington, 15Cure JM Foundation, Leesburg, 16Cure JM Foundation, Seattle, 17Arthritis Foundation, Arlington, 18Arthritis Foundation, Atlanta, 19Childhood Arthritis and Rheumatology Research Alliance, Whitehouse Station, 20Division of Rheumatology, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Mental health problems are common and often untreated in youth with rheumatologic disease, yet their relationship with disease features is poorly understood. We engaged…
  • Abstract Number: 1617 • ACR Convergence 2020

    New Juvenile Idiopathic Arthritis Quality Measure Set for the Pediatric Rheumatology Care and Outcomes Improvement Network

    Julia Harris1, Esi Morgan2, Sheetal Vora3, Mileka Gilbert4, Cagri Yildirim-Toruner5, Nancy Griffin6, Kerry Ferraro7, Stephanie Loos6, Tingting Qiu8, Anne Paul9, Jon Burnham10, Michelle Batthish11, Beth Gottlieb12, Danielle Bullock13, Melissa Hazen14, Ronald Laxer15, Tzielan Lee16, Melissa Mannion17, Judyann Olson18, Nancy Pan19, Michael Shishov20, Charles Spencer21, Jennifer E Weiss22 and C. April Bingham23, 1Children's Mercy Kansas City, Overland Park, KS, 2Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 3Atrium Health Levine Children's Hospital, Charlotte, NC, 4Medical University of South Carolina, Charleston, SC, 5Nationwide Children's Hospital, Houston, TX, 6Cincinnati Children's Hospital Medical Center, Cincinnati, 7Pediatric Rheumatology Care and Outcomes Improvement Network, Cincinnati, 8Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 9Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, 10Children's Hospital of Philadelphia, Philadelphia, PA, 11McMaster Children's Hospital, Hamilton, ON, Canada, 12Cohen Children's Medical Center, Lake Success, NY, 13University of Minnesota, Minneapolis, MN, 14Boston Children's Hospital, Boston, MA, 15The Hospital for Sick Children, Toronto, ON, Canada, 16Stanford University School of Medicine, Palo Alto, CA, 17University of Alabama at Birmingham, Birmingham, AL, 18Medical College of Wisconsin, Milwaukee, WI, 19Hospital for Special Surgery, New York, NY, 20Phoenix Children's Hospital, Phoenix, AZ, 21University of Mississippi, Jackson, MS, 22PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 23Penn State Children's Hospital, Allentown, PA

    Background/Purpose: The Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) is a learning network to support pediatric rheumatology centers in improving care delivery and patient…
  • Abstract Number: 1684 • ACR Convergence 2020

    Increase in Emergency Department Visits and Hospitalizations, Decrease in Outpatient Visits Following Transition to Adult Rheumatologic Care

    Paul Jensen1, Jessica Greco2, Kenneth Jackson3 and Stacy Ardoin4, 1Intermountain Healthcare, St. George, UT, 2Ohio State University/Nationwide Children's Hospital, Columbus, OH, 3Ohio State University Medical Center, Columbus, OH, 4Nationwide Children's Hospital, Columbus, OH

    Background/Purpose: Many children with rheumatic disease have active disease as adults, and health care gaps often occur in the transition from pediatric to adult care.…
  • Abstract Number: 1986 • ACR Convergence 2020

    Determinants of Variation in Pediatric Systemic Lupus Erythematosus Care Delivery

    Jon Burnham1, Rosemary Peterson1, Joy Ukaigwe1, Lynsey Cecere1, Andrea Knight2 and Joyce Chang1, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2Division of Rheumatology, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, ON, Canada

    Background/Purpose: Patients with pediatric systemic lupus erythematosus (pSLE) receive only a fraction of recommended care.  Moreover, variation in care delivery likely contributes to pervasive racial…
  • Abstract Number: 0175 • ACR Convergence 2020

    Identifying Immuno-phenotypes in Juvenile Localized Scleroderma with RNA Sequencing

    Christina Schutt1, Emily Mirizio2, Kaila Schollaert-Fitch2, Claudia Salgado3, Miguel Reyes-Mugica3 and Kathryn Torok2, 1University of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3University of Pittsburgh Medical Center, Pittsburgh

    Background/Purpose: Juvenile localized scleroderma (jLS) is an autoimmune disease of the skin and underlying tissue characterized by an early inflammatory infiltrate followed by fibrosis and…
  • Abstract Number: 0723 • ACR Convergence 2020

    Social Determinants of Health and Time to First Pediatric Rheumatology Appointment in Polyarticular Juvenile Idiopathic Arthritis

    Nayimisha Balmuri1, Victoria Cooley2, Linda Gerber2, Susan Goodman3, Bella Mehta3 and Karen Onel4, 1Hospital for Special Surgery, new york, NY, 2Weill Cornell Medicine, NY, NY, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 4Pediatric Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose: Patients with polyarticular JIA (pJIA) have a refractory disease course with increased risk for joint damage resulting in poor functional outcome and decreased quality of…
  • Abstract Number: 1153 • ACR Convergence 2020

    Trends in Timing of Biologic Use for Treatment of Systemic Juvenile Idiopathic Arthritis in the CARRA Registry

    Ginger Janow1, Timothy Beukelman2, Yukiko Kimura3, Rayfel Schneider4, Shalini Mohan5, Gail Rodich6 and Mary Beth Son7, 1Joseph M. Sanzari Children's Hospital at Hackensack Meridian Health, Hackensack, NJ, 2University of Alabama at Birmingham, Birmingham, AL, 3Hackensack Meridian School of Medicine, Hackensack, NJ, 4University of Toronto, The Hospital for Sick Children, Toronto, Canada, 5Genentech, Inc., South San Francisco, CA, 6Genentech, Mill Valley, CA, 7Boston Children's Hospital, Boston, MA

    Background/Purpose: The treatment of systemic juvenile idiopathic arthritis (SJIA) has changed dramatically over the past decade, associated with overall improvement in functional outcomes.  There may…
  • Abstract Number: 1176 • ACR Convergence 2020

    Identifying Targets to Improve the Assessment of Psychosocial Risk Factors in Adolescent Patients: Perspectives from Pediatric Rheumatology Fellows in the United States and Canada

    Jacob Spitznagle1, Nayimisha Balmuri1, Alexa Adams1, Karen Onel2, Sarah Taber1 and Nancy Pan1, 1Hospital for Special Surgery, New York, NY, 2Pediatric Rheumatology, Hospital for Special Surgery, New York, NY

    Background/Purpose: Adolescent patients cared for in the pediatric rheumatology clinic balance challenges related to psychosocial stressors and physical growth with the complexities of living with…
  • Abstract Number: 1665 • ACR Convergence 2020

    Sociodemographic and Clinical Predictors of Childhood-Onset SLE Disease Activity in the Childhood Arthritis and Rheumatology Research Alliance Registry

    Emily Smitherman1, Rouba Chahine1, Timothy Beukelman1, Andrea Knight2, AKM Rahman1, Mary Beth Son3, Jeffrey R Curtis4 and Aimee Hersh5, 1University of Alabama at Birmingham, Birmingham, AL, 2Division of Rheumatology, The Hospital for Sick Children and Department of Paediatrics, University of Toronto, Toronto, ON, Canada, 3Boston Children's Hospital, Boston, MA, 4Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 5University of Utah and Primary Children's Hospital, Salt Lake City

    Background/Purpose: Patients with childhood-onset systemic lupus erythematosus (cSLE) are at high risk for early morbidity and mortality, but predictors of moderate/high cSLE disease activity have…
  • Abstract Number: 1685 • ACR Convergence 2020

    Impact of the COVID-19 Pandemic Among Children with Rheumatic Diseases from Around the Globe

    Jonathan Hausmann1, Kevin Kennedy2, Salman Surangiwala3, Maggie Larche4, Karen Durrant5, Rashmi Sinha6 and Emily Sirotich4, 1Boston Children's Hospital / Beth Israel Deaconess Medical Center, Cambridge, MA, 2McMaster University, Hamilton, Canada, 3Queen’s School of Medicine, Kingston, Canada, 4McMaster University, Hamilton, ON, Canada, 5Autoinflammatory Alliance, San Francisco, CA, 6SJIA Foundation, Cincinnati

    Background/Purpose: Children with rheumatic diseases face unknown risks in the setting of the COVID-19 pandemic.  These children are often immunosuppressed due to their underlying disease…
  • Abstract Number: 1987 • ACR Convergence 2020

    Predictors of Adverse Outcomes in Patients with Childhood-Onset Systemic Lupus Erythematosus Transitioning to Adult Care

    Nicole Bitencourt1, Una Makris1, Elizabeth Solow1, Tracey Wright2 and Bonnie Bermas3, 1UT Southwestern Medical Center, Dallas, TX, 2UT Southwestern, Plano, TX, 3UTSouthwestern.edu, Dallas, TX

    Background/Purpose: The transition from pediatric to adult care is a vulnerable period and is linked to increased healthcare utilization and poor outcomes. We sought to…
  • Abstract Number: 0446 • ACR Convergence 2020

    Novel Ultrasound Image Acquisition Protocol and Scoring System for the Pediatric Ankle

    Patricia Vega-Fernandez1, Deirdre De Ranieri2, Edward Oberle3, Hulya Bukulmez4, Clara Lin5, Susan Shenoi6, Akaluck Thatayatikom7, Leandra Woolnough8, Kathleen Jo Corbin9, Heather Benham10, Emily Brunner11, Michael Henrickson1, Laura Ballenger3, Sara Haro12, Christina Schutt13, Jean-Philippe Proulx-Gauthier14, Ginger Janow15, Mekibib Altaye16, Amy Cassedy1, Johannes Roth17 and Tracy Ting1, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Lurie Children's Hospital, Chicago, IL, 3Nationwide Children's Hospital, Columbus, OH, 4MetroHealth Medical Center, Case Western Reserve, Pepper Pike, OH, 5Children's Hospital Colorado, Aurora, CO, 6Seattle Childrens Hospital, seattle, WA, 7Department of Pediatrics, University of Florida, Gainesville, FL, 8University of Florida, Gainesville, FL, 9Yale University School of Medicine, Woodbridge, CT, 10Texas Scottish RIte Hospital, North Richland Hills, TX, 11Geisinger, Bloomsburg, PA, 12UCSF, San Francisco, CA, 13University of Pittsburgh Medical Center, Pittsburgh, PA, 14CHU de Quebec - Universite Laval, Quebec, Canada, 15Joseph M. Sanzari Children's Hospital at Hackensack Meridian Health, Hackensack, NJ, 16Cincinnati Children's Hospital Medical Center, Cincinnati, 17University of Ottawa, Ottawa, ON, Canada

    Background/Purpose: The clinical decision-making process in pediatric arthritis lacks an objective, reliable bedside imaging tool. Although increasingly used for children, there is a need for…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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