Abstracts tagged "Pediatric rheumatology"

Abstract Number: 1672 • ACR Convergence 2020
Renal Activity Index for Lupus Nephritis Distinguishes Active Renal Disease Among Childhood Systemic Lupus Erythematosus Patients
Najla Aljaberi¹, Arjun Mathur², Steffy Jose³, Theresa Hennard⁴, Angela Merritt¹, Qing Ma⁵, James Rose⁵, Rashmi Sahay⁶, Chunyan Liu⁶, Scott Wenderfer⁷ and Hermine I Brunner⁸, ¹Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, ³Renal Section, Baylor College of Medicine and Texas Children's Hospital, Houston, ⁴Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Divison of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, ⁶Division of Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, ⁷Renal Section, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, ⁸PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
Background/Purpose: Renal involvement in childhood-onset systemic lupus erythematosus (cSLE) is a major cause of morbidity and mortality. Current tools to identify lupus nephritis (LN) fall…
Abstract Number: 1691 • ACR Convergence 2020
Applied Geostatistics in Pediatric Rheumatology – Spatial Clustering of IgA Vasculitis
Matej Sapina¹, Marijan Frkovic², Mario Sestan², Sasa Srsen³, Aleksandar Ovuka⁴, Mateja Batnozic Varga⁵, Nastasia Cekada², Karolina Kramaric⁶, Dario Brdaric⁷, Kresimir Milas⁵, Alenka Gagro⁸ and Marija Jelusic², ¹University Hospital Centre Osijek, Josip Juraj Strossmayer University of Osijek, Medical Faculty Osijek, Faculty of Dental Medicine and Health, Osijek, Croatia, Osijek, Osjecko-Baranjska, Croatia, ²University of Zagreb School of Medicine, University Hospital Centre Zagreb, Zagreb, Croatia, Zagreb, Grad Zagreb, Croatia, ³University Hospital Centre Split, University of Split School of Medicine, Split, Croatia, Split, Splitsko-Dalmatinska, Croatia, ⁴University Hospital Centre Rijeka, University of Rijeka School of Medicine, Rijeka, Croatia, Rijeka, Primorsko-Goranska, Croatia, ⁵University Hospital Centre Osijek, Josip Juraj Strossmayer University of Osijek, Medical Faculty Osijek, Croatia, Osijek, Osjecko-Baranjska, Croatia, ⁶University Hospital Centre Osijek, Josip Juraj Strossmayer University of Osijek, Faculty of Dental Medicine and Health Osijek, Croatia, Osijek, Osjecko-Baranjska, Croatia, ⁷Josip Juraj Strossmayer University of Osijek, Faculty of Dental Medicine and Health, Institute of Public Health for the Osijek-Baranja County, Osijek, Croatia, Osijek, Osjecko-Baranjska, Croatia, ⁸Children's Hospital Zagreb, Josip Juraj Strossmayer University of Osijek, Medical Faculty Osijek, Zagreb, Croatia, Zagreb, Grad Zagreb, Croatia
Background/Purpose: IgA vasculitis (IgAV) is the most common childhood vasculitis, which etiology seems to be related to the combination of genetic as well as environmental…
Abstract Number: 0597 • ACR Convergence 2020
Telemedicine in Pediatric Rheumatology During COVID-19: The PR-COIN Experience
Y. Ingrid Goh¹, Nancy Pan², Julia Harris³, Andrew Warmin⁴, Janalee Taylor⁴, Sheetal Vora⁵, Fatima Barbar-Smiley⁶, Jon Burnham⁷, Tzielan Lee⁸, Cagri Yildirim-Toruner⁹, Kendra Wiegand¹⁰ and Esi Morgan¹¹, ¹The Hospital for Sick Children, Toronto, ON, Canada, ²Hospital for Special Surgery, New York, NY, ³Children's Mercy Kansas City, Overland Park, KS, ⁴Cincinnati Children's Hospital, Cincinnati, OH, ⁵Atrium Health Levine Children's Hospital, Charlotte, NC, ⁶Nationwide Children's Hospital/The Ohio State University, Columbus, OH, ⁷Children's Hospital of Philadelphia, Philadelphia, PA, ⁸Stanford University School of Medicine, Palo Alto, CA, ⁹Nationwide Children's Hospital, Houston, TX, ¹⁰Cincinnati Children's Hospital, Cincinnati, ¹¹Cincinnati Children’s Hospital Medical Center, Cincinnati, OH
Background/Purpose: Healthcare teams were forced to rethink the way they practiced medicine during the COVID-19 pandemic. Many teams transitioned from conducting in-person visits to virtual…
Abstract Number: 0733 • ACR Convergence 2020
Practice Patterns for Tapering Medications in the Treatment of JIA-associated Uveitis
Ivan Foeldvari¹, Jens Klotsche², Sheila Angeles-Han³, Jordi Anton⁴, Gabriele Simonini⁵, Nadine Groesch² and Jean Baer⁶, ¹Head of the Hamburg Centre for Pediatric and Adolescence Rheumatology, Budapest, Hungary, ²German Rheumatism Research Center, Berlin, Germany, ³Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Sant Joan de Déu Hospital, Madrid, Spain, ⁵Anna Meyer Children's Hospital, Firenze, Italy, ⁶Hamburg Centre for Pediatric and Adolescence Rheumatology, Hamburg, Germany
Background/Purpose: Juvenile idiopathic arthritis associated uveitis (JIAU) is the most common extra-articular manifestation of JIA, and occurs in approximately 10% of affected children. Although there…
Abstract Number: 1165 • ACR Convergence 2020
Validation of Healthcare Claims Algorithms for Identification of Herpes Zoster Among Children with Autoimmune/Autoinflammatory Disease
Beth Rutstein¹, Sabrina Gmuca², Jeffrey S. Gerber² and Alexis Ogdie³, ¹The Children's Hospital of Philadelphia, Philadelphia, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, PA
Background/Purpose: Herpes zoster (HZ) is a known serious infectious complication in children with autoimmune/autoinflammatory disease and potentially exacerbated by immunomodulatory medications. Information on HZ burden…
Abstract Number: 1494 • ACR Convergence 2020
Patient-Reported Adverse Events, Quality of Life and Treatment Adherence in Juvenile Idiopathic Arthritis: Analysis of Two Large International Cohorts
Alessandra Alongi¹, Maria Trachana², Valda Stanevicha³, Laura Marinela Ailioaie⁴, Elena Tsitsami⁵, Angelo Ravelli⁶, Alessandro Consolaro⁶ and Nicolino Ruperto⁷, ¹IRCCS Istituto Giannina Gaslini, Genoa, Italy, ²Aristotle University of Thessaloniki, Thessaloníki, Greece, ³Riga Stradins University, Riga, Latvia, ⁴Alexandru Ioan Cuza University of Iasi, Iasi, Romania, ⁵Aghia Sophia Childrens Hospital, Athens, Greece, ⁶Università degli Studi di Genova, Genoa, Italy, ⁷Istituto Giannina Gaslini, Genova, Italy
Background/Purpose: Juvenile idiopathic arthritis (JIA) patients may experience significant medication-related adverse effects (AEs), which may adversely affect health-related quality of life (HRQOL), daily activities and…
Abstract Number: 1673 • ACR Convergence 2020
Principles of Pediatric Lupus Nephritis in a Contemporary Multi-Center Cohort
Kathleen Vazzana¹, Ankana Daga², Beatrice Goilav³, Ekemini Ogbu⁴, Daryl Okamura⁵, Catherine Park⁶, Rebecca Sadun⁷, Emily Smitherman⁸, Brian Stotter⁹, Scott Wenderfer¹⁰ and Laura Lewandowski¹¹, ¹National Institute of Health/Children's National Hospital, Washington, DC, ²Harvard, Boston, MA, ³The Children’s Hospital at Montefiore, Albert Einstein College of Medicine, Bronx, NY, ⁴Johns Hopkins University, Baltimore, MD, ⁵Seattle's Children's, Seattle, WA, ⁶Emory University, Atlanta, GA, ⁷Duke University, Durham, NC, ⁸University of Alabama at Birmingham, Birmingham, AL, ⁹Washington University School of Medicine, St. Louis, MO, ¹⁰Renal Section, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, ¹¹NIAMS, NIH, Rockville, MD
Background/Purpose: Lupus nephritis (LN) is a well-established and life-threatening manifestation of systemic lupus erythematosus (SLE) that is more common in children than adults. The demographics…
Abstract Number: 1692 • ACR Convergence 2020
Poor Physical Activity Levels and Cardiorespiratory Fitness Among Patients with Childhood-Onset Takayasu Arteritis in Remission
Camilla Astley¹, Saulo Gil², Gleice Clemente³, Maria Teresa Terreri⁴, Lucia Campos⁵, Nadia Aikawa⁵, Ana Lucia de-Sá Pinto², Rosa Pereira⁵, Hamilton Roschel² and Bruno Gualano², ¹University of Sao Paulo, Sao Paulo, Sao Paulo, Brazil, ²University of Sao Paulo, Sao paulo, Brazil, ³Federal University of Sao Paulo, Sao Paulo, Brazil, ⁴Federal University of São Paulo, São Paulo, Brazil, ⁵Hospital das Clínicas, Faculdade de Medicina da Universidade de Sao Paulo (HCFMUSP), Sao Paulo, Sao Paulo, Brazil
Background/Purpose: Childhood-onset Takayasu Arteritis (c-TA) is a rare, granulomatous, chronic large-vessel vasculitis that involves mostly the aorta and its major branches with a high mortality…
Abstract Number: 0608 • ACR Convergence 2020
Patient and Parent Perspectives in a Academic Pediatric Rheumatology Transition Clinic
Rebecca Overbury¹, Tracy Frech², John Bohnsack³, CJ Inman¹, Sara Stern¹, Karen James¹, Erin Treemarcki⁴ and Aimee Hersh⁴, ¹University of Utah and Primary Children's Hospital, Salt Lake City, UT, ²University of Utah and Salt Lake Veterans Affair Medical Center, Salt Lake City, UT, ³University of Utah and Primary Children's Hospital, Cincinnati, OH, ⁴University of Utah and Primary Children's Hospital, Salt Lake City
Background/Purpose: In November 2018 we initiated a transition clinic called ACCORD (Adult Center for Childhood Onset Rheumatic Disease). Our unique structure integrates an adult rheumatologist…
Abstract Number: 0734 • ACR Convergence 2020
Differences and Similarities Between down Syndrome-associated Arthritis and Juvenile Idiopathic Arthritis in the New Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry
Jordan Jones¹, Chelsey Smith², Daniel J Lovell³ and Mara Becker⁴, ¹Children's Mercy Kansas City, Kansas City, MO, ²Children's Mercy Kansas City, Holden, MO, ³PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ⁴Duke University School of Medicine, Durham, NC
Background/Purpose: Down syndrome-associated arthritis (DA) is under-recognized with delay in diagnosis (1). The majority of those with DA present with polyarticular, rheumatoid factor (RF) and…
Abstract Number: 1166 • ACR Convergence 2020
Use of Rituximab to Treat COPA Syndrome: A Multi-Institutional Cohort
Leigh Stubbs¹, Isabella Osuna², Tarin Bigley³, Michal Cidon⁴, Kristen Mengwasser⁵, Simon Helfgott⁶, Marietta DeGuzman⁷, Manuel Silva-Carmona⁸ and Tiphanie Vogel⁹, ¹Baylor College of Medicine, Houston, TX, ²Department of Pediatrics, Division of Rheumatology, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, USA, Houston, TX, ³Washington University in St. Louis, Saint Louis, MO, ⁴CHLA, Los Angeles, CA, ⁵Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Harvard Medical School and Brigham and Women’s Hospital, Boston, Massachusetts, USA, Boston, MA, ⁶BWH- HMS, Boston, MA, ⁷Baylor College of Medicine, Houston, ⁸Department of Pediatrics, Division of Pulmonology Medicine, Baylor College of Medicine and Texas Children’s Hospital, Houston, Texas, USA, Houston, TX, ⁹Baylor College of Medicine/Texas Children's Hospital, Houston, TX
Background/Purpose: Coatomer protein complex subunit α (COPA) syndrome is a rare genetic multisystem autoimmune disorder inherited in an autosomal dominant manner. Onset typically occurs in…
Abstract Number: 1495 • ACR Convergence 2020
Tofacitinib for the Treatment of Patients with Juvenile Idiopathic Arthritis: An Interim Analysis of Data up to 5.5 Years from an Open-label, Long-term Extension Study
Hermine I Brunner¹, Jonathan Akikusa², Eslam Al-Abadi², John Bohnsack³, Alina Lucica Boteanu², Gaelle Chedeville⁴, Ruben Cuttica², Wendy De La Pena⁴, Lawrence Jung⁴, Ozgur Kasapcopur², Katarzyna Kobusinska², Grant Schulert¹, Claudia Neiva², Rafael Rivas-Chacon⁴, Juan Cruz Rizo Rodriguez², Monica Vazquez-Del Mercado², Linda Wagner-Weiner⁴, Jennifer E Weiss¹, Carine Wouters², Ricardo M Suehiro⁵, Holly Posner⁶, Ann Wouters⁶, Keith S Kanik⁷, Zhen Luo⁸, Alberto Martini², Daniel J Lovell¹ and Nicolino Ruperto², ¹PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ²PRINTO, Istituto Giannina Gaslini, Genova, Italy, ³University of Utah and Primary Children's Hospital, Cincinnati, OH, ⁴PRCSG, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁵Pfizer Inc, Collegeville, PA, ⁶Pfizer Inc, New York, NY, ⁷Pfizer Inc, Groton, CT, ⁸Pfizer Inc, Shanghai, China (People's Republic)
Background/Purpose: Tofacitinib is an oral JAK inhibitor that is being investigated for JIA. We report the safety, tolerability, and efficacy of tofacitinib in patients (pts)…
Abstract Number: 1674 • ACR Convergence 2020
Pediatric and Adolescent One Year Protocol Kidney Biopsies Should Be Performed, Even in Patients with Complete Remission of Their Lupus Nephritis
Peter Yorgin¹, Suhas Radhakrishna¹, Caitlin Carter¹, Johanna Chang¹, Katayoon Shayan¹, Lieuko Nguyen¹, Peter Chiraseveenuprapund¹ and Robert Sheets², ¹UCSD/Rady Children's Hospital, San Diego, CA, ²University of California San Diego, San Diego, CA
Background/Purpose: The value of one-year protocol kidney biopsies in children who have proliferative lupus nephritis (LN) is unclear, particularly in patients who meet CARRA criteria…
Abstract Number: 1693 • ACR Convergence 2020
Evaluation of B-cell Depletion with Rituximab and IVIG Concurrent Treatment in Pediatric Autoimmune Brain Disease
Alexis Wilsey¹, Laura Cannon², Stephanie Johannes² and Heather Van Mater², ¹Duke University School of Medicine, Durham, ²Duke University, Durham, NC
Background/Purpose: Rituximab is standard therapy for autoimmune brain disease (ABD) including autoimmune encephalitis (AE) and Neuromyelitis Optica Spectrum Disease (NMOSD). Recommendations for continuing concurrent intravenous…
Abstract Number: 0634 • ACR Convergence 2020
Influenza Knowledge and Barriers to Vaccination in Immunosuppressed Patients in the Pediatric Rheumatology Clinic
Julia Harris¹, Maria Ibarra², Michael Holland², Kelly Jensen³, Emily Fox², Jordan Jones², Leslie Favier⁴, Ashley Sherman², Chelsey Smith⁵ and Ashley Cooper², ¹Children's Mercy Kansas City, Overland Park, KS, ²Children's Mercy Kansas City, Kansas City, MO, ³Children's Mercy Kansas City, Kansas City, ⁴Children's Mercy Kansas City, Leawood, KS, ⁵Children's Mercy Kansas City, Holden, MO
Background/Purpose: Many pediatric rheumatology patients are at increased risk of influenza due to immunosuppressive medication use. Annual influenza vaccination is recommended for all children by…

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