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Abstracts tagged "Patient reported outcomes"

  • Abstract Number: 1448 • ACR Convergence 2022

    Utility of Digital Signals and Patient Reported Data Gathered in a Decentralized Study to Predict SLE Patient-Reported Flares

    Eldon Jupe1, Gerald Lushington2, Mohan Purushothaman1, Fabricio Pautasso1, Georg Armstrong1, Arif Sorathia1, Jessica Crawley1, Vijay Nadipelli3, Bernie Rubin4, Ryan Newhardt1, Melissa Munroe1 and Brett Adelman1, 1Progentec Diagnostics, Inc., Oklahoma City, OK, 2Progentec Diagnostics, Inc., Oklahoma City, OR, 3GlaxoSmithKline, Philadelphia, PA, 4GlaxoSmithKline, US Medical Affairs and Immuno-inflammation, Durham, NC

    Background/Purpose: Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease characterized by varied immune dysregulation. SLE patients often experience episodic flares, leading to organ damage…
  • Abstract Number: 1954 • ACR Convergence 2022

    Development of the Patient-Important Outcomes Data Repository (PIONEER) for Rheumatic Diseases; An Enhanced Database Combining Electronic Medical Data with Insight from Chart Reviews

    Simon Helfgott1, Kent Kwas Huston2, Jasvinder singh3, Nehad Soloman4, Jeremy Broestl5, Kimmi Cox5, Kelsey Milligan5 and Colin Edgerton6, 1Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Kansas City Physician Partners Center for Rheumatic Disease, Kansas City, MO, 3University of Alabama at Birmingham, Birmingham, AL, 4Arizona Arthritis & Rheumatology Associates, P.C., Peoria, AZ, 5Trio Health, Louisville, CO, 6Articularis Healthcare, Sullivans Island, SC

    Background/Purpose: Clinical and non-clinical forces contribute to real-world treatment effectiveness, yet most studies focus on efficacy in an idealized setting. To identify factors impacting clinical…
  • Abstract Number: 2243 • ACR Convergence 2022

    Patient Reported Outcomes from a Randomized Phase 3 Trial of Sarilumab in Polymyalgia Rheumatica

    Vibeke Strand1, Jennifer Sloane Lazar2, Michael C Nivens3, Jingdong Chao4, Stefano Fiore5, Angeliki Giannelou6, Lita Araujo7 and Jerome Msihid8, 1Stanford University School of Medicine, Stanford, CA, 2Sanofi, Delray Beach, FL, 3Regeneron Pharmaceuticals, Inc., Tarrytown, NY, NY, 4Regeneron Pharmaceuticals, Inc.,, Tarrytown, NY, 5Sanofi, Bridgewater, NJ, 6Regeneron Pharmaceuticals, Inc., Hoboken, NJ, 7Sanofi, Cambridge, MA, 8Sanofi, Chilly-Mazarin, France

    Background/Purpose: Polymyalgia rheumatica (PMR) is a common inflammatory rheumatic disease in the elderly. The phase 3 SAPHYR trial (NCT03600818) assessed the efficacy and safety of…
  • Abstract Number: 0187 • ACR Convergence 2022

    Patient-reported Outcomes and Quality of Life in Patients with Rheumatoid Arthritis Treated with GP2015: Final Results from a Real-world Study

    Ayman Askari1, Marc Schmalzing2, Herbert Kellner3, Rafaela Ortega-Castro4, Julio Cesar Vázquez Perez-Coleman5, Foti Rosario6, Sławomir Jeka7, Boulos Haraoui8, Yannick Allanore9, Masiur Rahman10, Fabricio Furlan10, Sohaib Hachaichi11 and Tom Sheeran12, 1The Robert Jones and Agnes Hunt Orthopaedic Hospital, Oswestry, England, United Kingdom, 2University Hospital Wuerzburg, Wuerzburg, Germany, 3Schwerpunktpraxis für Rheumatologie und Gastroenterologie, Munich, Germany, 4IMIBIC/University of Cordoba/Reina Sofia Hospital, Cordoba, Spain, 5University Hospital Complex of Ferrol, A Coruña, Spain, 6Policlinico G. Rodolico-S.Marco Hospital, Catania, Italy, 7University Hospital No 2 in Bydgoszcz Collegium Medicum UMK, Clinic and Department of Rheumatology and Connective Tissue Diseases, Bydgoszcz, Poland, 8Institut de rhumatologie de Montréal, Montréal, QC, Canada, 9Department of Rheumatology A, Descartes University, APHP, Cochin Hospital, Paris, France, Paris, France, 10Sandoz Hexal AG, Holzkirchen, Germany, 11Hexal AG (A Sandoz company), Holzkirchen, Germany, 12New Cross and Cannock Chase Hospitals, University of Wolverhampton, Cannock, United Kingdom

    Background/Purpose: COMPACT is a non-interventional study evaluating the persistence, effectiveness, safety and patient-reported outcomes (PROs) in patients with rheumatoid arthritis (RA), axial-spondyloarthritis or psoriatic arthritis…
  • Abstract Number: 0313 • ACR Convergence 2022

    Olokizumab Improves Patient Reported Outcomes in Moderate to Severely Active Rheumatoid Arthritis Patients Inadequately Controlled by Methotrexate (MTX-IR): Results from the Phase III Randomized Controlled Trial

    Vibeke Strand1, Evgeny Nasonov2, Tatiana Lisitsyna2, Alexander Lila2, Sofia Kuzkina3, Mikhail Samsonov4 and Eugen Feist5, 1Stanford University School of Medicine, Stanford, CA, 2V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, 3R-Pharm, Moscow, Russia, 4R-Pharm JSC, Moscow, Russia, 5Helios Clinic Vogelsang-Gommern, cooperation partner of the Otto von Guericke University Magdeburg, Magdeburg, Germany

    Background/Purpose: Olokizumab (OKZ) is an interleukin-6-inhibitor for treatment of Rheumatoid Arthritis (RA). In these analyses, we present patient reported outcomes (PROs) reported by MTX-IR patients…
  • Abstract Number: 0444 • ACR Convergence 2022

    Prevalence of Frailty and Associated Factors in Patients with Vasculitis

    Sebastian Sattui1, John Stadler2, Cristina Burroughs3, Kalen Larson2, Christine Yeung4, Peter Merkel5 and Robert Spiera6, 1University of Pittsburgh, Pittsburgh, PA, 2Vasculitis Foundation, Kansas City, MO, 3University of South Florida, Tampa, FL, 4University of Pennsylvania, Philadelphia, 5University of Pennsylvania, Philadelphia, PA, 6Hospital for Special Surgery, New York, NY

    Background/Purpose: Frailty is a syndrome characterized by an increased vulnerability to stressors and is associated with disability and early mortality. Frailty may be accelerated in…
  • Abstract Number: 0855 • ACR Convergence 2022

    Change in Short Term Outcomes Following Tolerated Disease Activity Level for Individuals with Juvenile Idiopathic Arthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry

    Melissa Mannion1, Fenglong Xie1, Timothy Beukelman1, Jeffrey Curtis2 and , for the CARRA Registry Investigators3, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Alabama at Birmingham, Hoover, AL, 3CARRA, Washington, DC

    Background/Purpose: Current recommendations suggest treatment escalation for juvenile idiopathic arthritis (JIA) until the disease activity target is reached, ideally inactive or low disease activity. Our…
  • Abstract Number: 1336 • ACR Convergence 2022

    Productivity Analysis in Patients with Idiopathic Inflammatory Myopathies and Relationship with Quality of Life and Emotional Domain: Preliminary Data from a Monocentric Cohort

    Chiara Cardelli1, Michele Diomedi1, Simone Barsotti1, Alessandra Tripoli2, Linda Carli1 and Marta Mosca1, 1Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy, 2Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Pisa, Vecchiano, Italy

    Background/Purpose: Idiopathic Inflammatory Myopathies (IIM) are chronic diseases often causing disability in patients, associated with both disease activity and damage accrual. These conditions might reduce…
  • Abstract Number: 1451 • ACR Convergence 2022

    Delayed Sleep Phase Syndrome Characterizes Circadian Disorder in Patients with Active SLE

    Christina Stankey1, Philip Chu2, Alicia Hinze3, Lily McMorrow1, Alia El-Qunni1, Deepali Sen1, Seth Eisen1, Yo-El Ju1 and Alfred Kim1, 1Washington University School of Medicine, St. Louis, MO, 2Duke University Hospital, Raleigh, NC, 3Mayo Clinic - Rochester, MN, Rochester, MN

    Background/Purpose: Poor sleep quality is a common complaint of patients with SLE. Although chronic sleep disruption is known to drive circadian rhythm disorders, the effects…
  • Abstract Number: 1973 • ACR Convergence 2022

    Association Between Activity Limitations, Sleep Disturbance, Pain Sensitivity, Pain Intensity, and Widespread Pain in Adults with Rheumatoid Arthritis

    Burcu Aydemir1, Jing Song2, Lutfiyya Muhammad3, Daniela Grimaldi1, Kathryn Reid1, Phyllis Zee1, Rowland Chang4 and Yvonne Lee1, 1Northwestern University, Chicago, IL, 2Northwestern University, Evanston, IL, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Northwestern University Division of Rheumatology, Chicago, IL

    Background/Purpose: Despite treatment with strong immunosuppressive medications, more than half of patients with rheumatoid arthritis (RA) still report pain. Pain can spread from joint sites…
  • Abstract Number: 2246 • ACR Convergence 2022

    Rheumatoid Arthritis Patient Discordance with Provider Treatment Goals Is Associated with Poorer RA Outcomes

    Kelly O'Neill1, Pamela Sinicrope2, Cynthia Crowson3, Kathryne Marks4, Rachel Giblon5, Elena Myasoedova2 and John Davis2, 1Rheumatoid Patient Foundation, Winter Springs, FL, 2Mayo Clinic, Rochester, MN, 3Mayo Clinic, Eyota, MN, 4Brigham and Women's Hospital, Boston, MA, 5Mayo Clinic, Rochester, MN, Rochester, MN

    Background/Purpose: We previously reported on themes in rheumatoid arthritis (RA) patients' treatment goals which associated with aspects of rheumatology care such as presence of a…
  • Abstract Number: 0191 • ACR Convergence 2022

    Patient-reported Outcomes to Assess Dyspnea in Connective Tissue Diseases, Interstitial Lung Disease and Pulmonary Hypertension, a Systematic Literature Review of Measurement Properties

    Jacqueline Lemmers1, Madelon Vonk2 and Els Ende, van den3, 1Radboud University Medical Centre Nijmegen, Nijmegen, Netherlands, 2Department of Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands, 3Radboudumc, Nijmegen, Netherlands

    Background/Purpose: This COnsensus-based Standards for the selection of health Measurement INstruments (COSMIN)-based systematic review aims to identify and summarize the quality of measurement properties of…
  • Abstract Number: 0314 • ACR Convergence 2022

    Olokizumab Improved Patient Reported Outcomes in TNF Incomplete Responder (TNF-IR) Rheumatoid Arthritis Patients: Results from the Phase III Randomized Controlled Trial

    Vibeke Strand1, Evgeny Nasonov2, Tatiana Lisitsyna2, Alexander Lila2, Sofia Kuzkina3, Mikhail Samsonov4 and Eugen Feist5, 1Stanford University School of Medicine, Stanford, CA, 2V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia, 3R-Pharm, Moscow, Russia, 4R-Pharm JSC, Moscow, Russia, 5Helios Clinic Vogelsang-Gommern, cooperation partner of the Otto von Guericke University Magdeburg, Magdeburg, Germany

    Background/Purpose: Olokizumab (OKZ) is an interleukin-6-inhibitor for treatment of rheumatoid arthritis (RA). In these analyses we present patient reported outcomes (PROs) reported by TNF-IR patients…
  • Abstract Number: 0503 • ACR Convergence 2022

    The Effect of Social Isolation on 1-Year Outcomes After Surgical Repair of Low Trauma Hip Fracture

    Robyn Lipschultz1, Dina Sheira1, Marianna Frey2, Mangala Rajan3, Joseph Lane1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of Rochester School of Medicine and Dentistry, New York, NY, 3Weill Cornell Medicine, New York, NY

    Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over 65 years old. Social isolation—how integrated a…
  • Abstract Number: 0863 • ACR Convergence 2022

    Effect of Glucocorticoids on Patient Reported Outcomes in Patients Started on a Biologic Consensus Treatment Plan for the ‘First Line Options for Systemic JIA Treatment’ (FROST) Study

    Karen James1, George Tomlinson2, Tim Beukelman3, Laura Schanberg4, Anne Dennos5, VIncent Del Gaizo6, Marian Jelinek7, Erin Pfeifer8, Shalini Mohan9 and Yukiko Kimura10, 1University of Utah, Salt Lake City, UT, 2University of Toronto, Toronto, ON, Canada, 3Childhood Arthritis and Rheumatology Research Alliance (CARRA), Birmingham, AL, 4Duke University Medical Center, Durham, NC, 5Duke University, Durham, NC, 6Childhood Arthritis and Rheumatology Research Alliance (CARRA), Durham, NC, 7Childhood Arthritis and Rheumatology Research Alliance (CARRA), Duke, 8Genentech, Englewood, NJ, 9Genentech, San Diego, 10Hackensack Meridian Health, New York, NY

    Background/Purpose: Systemic Juvenile Idiopathic Arthritis (sJIA) is a systemic autoinflammatory disease characterized by high fevers, rash and arthritis. Current treatment regimens often involve biologic (anti-IL-1…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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