Abstracts tagged "osteoporosis"

Abstract Number: 1206 • ACR Convergence 2020
Associations of Vascular and Bone Status in Anti-TNF-treated Rheumatoid Arthritis and Ankylosing Spondylitis Patients
Anita Pusztai¹, Attila Hamar², Monika Czókolyová², Katalin Gulyás², Ágnes Horváth², Edit Végh², Zsófia Pethő², Szilvia Szamosi², Emese Balogh², Nóra Bodnár², Ágnes Szentpétery³, Harjit Bhattoa², György Kerekes², Balázs Juhász², Éva Szekanecz², Katalin Hodosi², Andrea Domján², Sándor Szántó², Hennie Raterman⁴, Willem Lems⁵, Zoltán Szekanecz² and Gabriella Szűcs², ¹University of Debrecen Faculty of Medicine, Department of Rheumatology, Debrecen, Hungary, ²University of Debrecen, Debrecen, Hungary, ³Uppsala University Hospital, Uppsala, Sweden, ⁴Northwest Clinics, Alkmaar, Netherlands, ⁵Amsterdam Rheumatology and Immunology Centre, Amsterdam, Netherlands
Background/Purpose: Cardiovascular (CV) disease and osteoporosis (OP) have become increasing challenges in the ageing population, even more in patients with inflammatory rheumatic diseases, such as…
Abstract Number: 0106 • ACR Convergence 2020
A Machine Learning-derived Radiomics Nomogram for Diagnosis of Osteoporosis and Osteopenia
Qianrong Xie¹, Yue Chen², Yimei Hu³, Fanwei Zeng⁴, Pingxi Wang⁴, Lin Xu⁵, Jianhong Wu⁶, Jie Li¹, Jing Zhu⁷, Ming Xiang⁸ and Fanxin Zeng⁹, ¹Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, China (People's Republic), ²Department of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), ³Department of Orthopedics, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China (People's Republic), ⁴Department of bone disease, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁵Department of medical imaging, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁶Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), ⁷Department of Rheumatology and Immunology, Sichuan Academy of Medical Sciences & Sichuan Provincial People’s Hospital, Chengdu, China (People's Republic), ⁸Department of Orthopedics, Sichuan Provincial Orthopedic Hospital, Chengdu, China (People's Republic), ⁹Department of Clinical Research Center, Dazhou Central Hospital, Dazhou, Sichuan, China (People's Republic)
Background/Purpose: To discriminate osteoporosis and osteopenia using a quantitative computed tomography (QCT) radiomics signatures and clinical variables.Methods: This retrospective study enrolled 635 patients with QCT images and clinical characteristics from November…
Abstract Number: 0124 • ACR Convergence 2020
Appropriate Timing of Denosumab Dosing and Subsequent Therapy After Discontinuation: An Academic Medical Center Experience
Hugo Raposo¹, Daniel Lindstrom¹ and Jonathan Cheah², ¹University of Massachusetts Medical School, Worcester, MA, ²University of Massachusetts Medical School, Shrewsbury, MA
Background/Purpose: Denosumab, a monoclonal antibody that binds to the receptor activator of nuclear factor kappa-B ligand (RANKL) is a popular choice for osteoporosis therapy. However,…
Abstract Number: 1336 • ACR Convergence 2020
Bone Mineral Density, Trabecular Bone Score and Proximal Femur 3D-DXA Analysis in Psoriatic Diseases
Eric Toussirot¹, Renaud Winzenrieth², Maxime Desmarets³, Daniel Wendling⁴, Francois Aubin⁵ and Gilles Dumoulin⁶, ¹CIC biotherapies, Besançon University Hospital, Besançon, France, ²GALGO medical, Barcelona, Spain, ³INSERM CIC-1431, Besancon, France, ⁴CHU Besançon, department of rheumatology, Besancon, France, ⁵Dermatology, Besancon, France, ⁶Laboratoire de Biochimie Médicale, UF de Biochimie Endocrinienne et Métabolique, Besancon, France
Background/Purpose: current data regarding areal bone mineral density (aBMD) in patients with psoriasis (PsO) or psoriatic arthritis (PsA) are conflicting. Results on Trabecular Bone Score…
Abstract Number: 1971 • 2019 ACR/ARP Annual Meeting
CD39 Produced from Human Gingiva-Derived Mesenchymal Stem Cells Regulates the Balance of Osteoclasts and Osteoblasts Through Wnt / β-catenin Pathway in Osteoporosis
Wenbin Wu¹, Julie Wang ², feng huang ¹, limin Rong ¹ and Song Guo Zheng ³, ¹Sun Yat-sen University, Guangzhou, ²Ohio State University, columbus, ³Ohio State College of Medicine, Columbus, OH
Background/Purpose: Osteoporosis led to severe bone-related diseases and increased mortality and health care costs. Existing treatments failed to reduce the risk of fractures in patients,…
Abstract Number: 2222 • 2019 ACR/ARP Annual Meeting
Bone Health: An Independent Predictor of Coronary Artery Disease
Lilian Bizzocchi¹, Maria Salgado ¹, Bhavin Chokshi ¹, Navneet Kaur ¹, Oscar Mena ¹ and Michal Packman ², ¹Jacobi Medical Center, Bronx, NY, ²North Central Bronx Hospital, Bronx, NY
Background/Purpose: An association between low bone mineral density (BMD) and cardiovascular events has been shown. The calcification process observed in atherosclerosis and bone mineralization have…
Abstract Number: 2102 • 2019 ACR/ARP Annual Meeting
First-line Antiretroviral Therapy with Tenofovir Produces Deleterious Effects on Bone and an Increase in Proinflammatory Cytokines Expression After 12 Months of Treatment in Naïve HIV Patients
Francisco Conesa-Buendia¹, Patricia Atencio ¹, Alfonso Cabello ², Patricia Llamas-Granda ³, Ignacio Mahillo-Fernández ⁴, Raquel Largo ⁵, Gabriel Herrero-Beaumont ⁵, Miguel Gorgolas ¹ and Aranzazu Mediero ¹, ¹IIS-FUNDACION JIMENEZ DIAZ, Madrid, Spain, ²IIS FUNDACION JIMENEZ DIAZ, Madrid, Spain, ³IIS-FUNDACION JIMENEX DIAZ, Madrid, Spain, ⁴IIS- FUNDACION JIMENEZ DIAZ, Madrid, Spain, ⁵IIS-Fundación Jiménez Díaz, Madrid, Madrid, Spain
Background/Purpose: For almost two decades, bone alterations have been observed in the course of HIV infection, characterized by a marked decrease in bone mineral density…
Abstract Number: 2224 • 2019 ACR/ARP Annual Meeting
Parkinson’s Disease and Risk of Fractures : A Meta Analysis of Cohort Studies
marion louvois¹, stéphanie Ferrero ¹, Thomas Barnetche ², christian roux ¹ and Véronique Breuil ¹, ¹university of nice, nice, France, ²university of bordeaux, bordeaux, France
Background/Purpose: Parkinson's disease is a common neurodegenerative disorder in older adults. Parkinson's patients have an increase risk of falls. More over, previous studies have shown…
Abstract Number: 2204 • 2019 ACR/ARP Annual Meeting
Fragility Fractures in a Community Setting: Clinical Characteristics, Care Gaps, and Outcomes
Rachel Kneeland¹, Keile Wahle ¹, Ishwar Gill ¹, Yangyang Liu ² and Monika Starosta ³, ¹Department of Internal Medicine, Advocate Lutheran General Hospital, Park Ridge, IL, ²Russell Center for Research & Innovation, Advocate Lutheran General Hospital, Park Ridge, IL, ³Department of Rheumatology, Advocate Lutheran General Hospital, Park Ridge, IL
Background/Purpose: Osteoporosis-related fragility fractures contribute to significant morbidity and mortality. The risk of subsequent hip fracture is significantly increased after initial fracture, with some reports…
Abstract Number: 2225 • 2019 ACR/ARP Annual Meeting
Systematic Osteoporosis Screening in Chronic Obtructive Pulmonary Disease (Study of Correlation Between Pulmonary Functions Tests and Bone Parameters): Emphysematous Status Is Linked to Low Bone Density and Osteoporosis
Olivier Malaise¹, Cécile André ¹, Laurence Seidel ², Florence Schleich ³, Renaud Louis ³ and Michel Malaise ¹, ¹Rheumatology department, CHU and University of Liège, Liège, Belgium, ²Biostatistics department, CHU and University of Liège, Liège, Belgium, ³Pneumology department, CHU and University of Liège, Liège, Belgium
Background/Purpose: Chronic obstructive pulmonary disease (COPD) is usually considered as a risk factor for osteoporosis. However, COPD is an heterogeneous disease with different phenotypes, based…
Abstract Number: 151 • 2019 ACR/ARP Annual Meeting
Implementation of Recommendations for Prevention of Glucocorticosteroid-Induced Osteoporosis in Hospitalized Patients
Tal Gazitt¹, Muna Elias ¹, Joy Feld ¹, Idit Lavi ¹, Amir Haddad ¹, Rema Bishara-Garzuzi ¹, Muhanad Abu Elhija ¹, Adi Kibari ¹ and Devy Zisman ², ¹Carmel Hospital, Haifa, Israel, ²Carmel Hospital and Ruth and Bruce Rappaport Faculty of Medicine, Technion, Israel, Haifa, Israel
Background/Purpose: Glucocorticosteroid-induced osteoporosis (GIO) is the most common cause of secondary osteoporosis but is under-diagnosed and under-treated. Most professional guidelines recommend as a first step…
Abstract Number: 2206 • 2019 ACR/ARP Annual Meeting
MRI-based Textural Analysis of Trabecular Bone: A Novel Method for the Opportunistic Screening of Bone Quality
Jonathan Cheah¹, Matthew Koff ¹, Ryan Breighner ¹, Bin Lin ¹, Conor Jones ², Janice Havasy ², Mikas Grewal ¹ and Emily Stein ¹, ¹Hospital for Special Surgery, New York, NY, ²Weill Cornell Medicine, New York, NY
Background/Purpose: A major obstacle to the treatment of osteoporosis and prevention of fractures is that many at-risk patients are never screened. Dual energy x-ray absorptiometry…
Abstract Number: 2226 • 2019 ACR/ARP Annual Meeting
Factors Contributing to Fracture in Pernicious Anemia Patients Presenting with Symptomatic Subacute Vertebral Compression Fractures
Michael Lovy¹, Nir Ben-Shlomo ² and Jacob Hattenbach ³, ¹Desert Oasis Healthcare, Palm Springs, CA, ²Ben-Gurion Medical School, Beer Sheva, Israel, ³College of Osteopathic Medicine of the Pacific, Pomona
Background/Purpose: Pernicious anemia (PA) has been associated with both low spine BMD and increased fracture risk in retrospective cohort studies. The cause of these observations…
Abstract Number: 270 • 2019 ACR/ARP Annual Meeting
Outcomes of a Fracture Liaison Service at an Academic Health Center
Micah Yu¹, Donna Jose ², Parke Hudson ², Christina Downey, MD ³, Wesley Phipatanakul ², Silvana Giannelli ², Kevin Codorniz ⁴ and Karina Torralba ⁵, ¹Loma Linda University Medical Center, loma linda, ²Loma Linda University, Loma Linda, ³Loma Linda University Medical Center, Loma LInda, CA, ⁴[email protected], Loma Linda, ⁵Loma Linda University School of Medicine, Loma Linda, CA
Background/Purpose: Osteoporosis is associated with increased morbidity and mortality. There is a 60% risk of a subsequent fracture for patients who have had one fracture,…
Abstract Number: 2207 • 2019 ACR/ARP Annual Meeting
Bone Mineral Density and Microarchitecture Among Chinese Patients with Rheumatoid Arthritis
Shangyi Jin¹, Evelyn Hsieh ², Weibo Xia ³, Mengtao Li ⁴, Qian Wang ¹ and Xiaofeng Zeng ¹, ¹Department of Rheumatology, Key Laboratory of Rheumatology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, People’s Republic of China, Beijing, Beijing, China (People's Republic), ²Section of Rheumatology, Yale School of Medicine, NewHaven, CT, ³Department of Endocrinology, Key Laboratory of Endocrinology, Ministry of Health, Peking Union Medical College Hospital, Chinese Academy of Medical Science, Beijing, Beijing, China (People's Republic), ⁴Dept. of Rheumatology, Peking Union Medical College Hospital (West Campus), Beijing, China, Beijing, China (People's Republic)
Background/Purpose: To evaluate alterations of bone mineral density and microarchitecture in patients with rheumatoid arthritis (RA). We also aimed to identify potential factors associated with…

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