Abstracts tagged "Osteoarthritis"

Abstract Number: 2656 • ACR Convergence 2024
Short-Term Effectiveness of a Walk with Ease Program Delivered by Telephone on Arthritis-Related Symptoms, Function, and Physical Activity
Christine Pellegrini, Sara Wilcox, Yesil Kim, Katherine Devivo, Scott Jamieson, Kailyn Horn and Daniel Heidtke, University of South Carolina, Columbia, SC
Background/Purpose: Walk With Ease (WWE) is a 6-week arthritis-appropriate evidence-based physical activity program traditionally offered in a face-to-face format. However, as many populations encounter participation…
Abstract Number: 0175 • ACR Convergence 2024
Do Knee Strength and Pain Relate to Developing Stair Climbing Difficulty for Knee Osteoarthritis?
Jason Jakiela¹, Yvonne Golightly², Sydney Liles³, Judy Foxworth⁴ and Daniel White⁵, ¹Winston-Salem State University, Winston-Salem, NC, ²University of Nebraska Medical Center, Omaha, NE, ³University of Delaware, Elkton, MD, ⁴Winston-Salem State University, Elon, NC, ⁵University of Delaware, Newark, DE
Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation in older adults, and stair climbing difficulty is often the first-reported limitation. Previous work…
Abstract Number: 0981 • ACR Convergence 2024
The Causal Effect of Sex Hormone-related Drugs on the Risk of Osteoarthritis – A Mendelian Randomization Study
Xing Xing¹, Ziyuan Shen², Jianan Zhu³, Yining Wang², Xingzhong Jin⁴ and Guoqi Cai², ¹Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Baltimore, MD, ²Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, China (People's Republic), ³Department of Biostatistics, School of Public Health, New York University, New York, NY, ⁴Centre for Big Data Research in Health, University of New South Wales, Sydney, Australia
Background/Purpose: Osteoarthritis (OA) is a prevalent joint disorder characterized by joint pain, disability, and the loss of articular cartilage, imposing a significant burden on patients…
Abstract Number: 1189 • ACR Convergence 2024
Certain Dosages of Fasinumab Provides Superior Benefits over Placebo in Mitigating Osteoarthritis Symptoms Albeit at Increased Health Detriments: A Systematic Review and Meta-Analysis
Muhammad Sohaib Khan¹, Wania Moeen², Umm E Salma Shabbar Banatwala², Muhammad Usman², Umar Mahmood², Syed Ashad Ahmed Fatmi², Syed Muhammad Muneeb Akhtar², Hania Shahzad³, Muhammad Talal Ibrahim⁴, Nisar Ahmed⁵, Badaruddin Sahito² and Muhammad Sohaib Asghar⁶, ¹Dow University of Health Sciences, Karachi, Pakistan, ²Dow University of Health Sciences, Karachi, Sindh, Pakistan, ³UC Davis Health, Sacramento, CA, ⁴The Ohio State University Wexner Medical Center, Columbus, OH, ⁵Rapido’s Clinica Familiar, Chicago, ⁶AdventHealth, Sebring, FL
Background/Purpose: Fasinumab, a newly developed anti-nerve growth factor monoclonal antibody, is currently under investigation for its potential to alleviate symptoms in osteoarthritis patients. This meta-analysis…
Abstract Number: 1205 • ACR Convergence 2024
OARSI Initiative to Develop Classification Criteria for Early-Stage Symptomatic Knee OA (EsSKOA): What Should Be Considered in the Differential Diagnosis of EsSKOA?
Gillian Hawker¹, Lauren King¹, Jean Liew², Quike Wang³, Armaghan Mahmoudian⁴, Nuria Jansen⁵, Ian Stanaitis⁶, Jos Runhaar⁵, Tom Appleton⁷, Aleksandra Turkiewicz⁸, Martin Englund⁹, Stefan Lohmander⁹, Ida Kristin Haugen¹⁰ and Tuhina Neogi¹¹, and OARSI Early-stage Symptomatic Knee Osteoarthritis Initiative, ¹University of Toronto, Toronto, ON, Canada, ²Boston University, Boston, MA, ³Shanghai Sixth People's Hospital, Shanghai, China (People's Republic), ⁴University of West Florida, Pensacola, FL, ⁵Erasmus MC University Medical Center Rotterdam, Rotterdam, Netherlands, ⁶Women's College Hospital, Toronto, ON, Canada, ⁷The University of Western Ontario, London, ON, Canada, ⁸,Lund University, Lund, Sweden, ⁹Lund University, Lund, Sweden, ¹⁰Diakonhjemmet Hospital, Oslo, Norway, ¹¹Boston University Chobanian & Avedisian School of Medicine, Boston, MA
Background/Purpose: Osteoarthritis Research Society International (OARSI) has launched an initiative to develop classification criteria for early-stage symptomatic knee osteoarthritis (EsSKOA). In individuals with undiagnosed knee…
Abstract Number: 1655 • ACR Convergence 2024
Peroxisome Proliferator-Activated Receptor α Is a Disease-Modifying Target for Osteoarthritis
UXIA NOGUEIRA-RECALDE¹, christian García-Dominguez², Patricia Diaz-Rodriguez³, francisco J Blanco⁴, eduardo Dominguez³ and BEATRIZ CARAMES¹, ¹INSTITUTO DE INVESTIGACION BIOMEDICA DE A CORUÑA (INIBIC), A Coruña, Spain, ²IINSTITUTO DE INVESTIGACION BIOMEDICA DE A CORUÑA (INIBIC), A Coruña, Spain, ³UNIVERSIDAD DE SANTIAGO DE COMPOSTELA, SANTIAGO DE COMPOSTELA, Spain, ⁴INIBIC-University of A Coruña, A Coruña, Spain
Background/Purpose: Disease-modifying drugs (DMOADs) to prevent Osteoarthritis (OA) are an urgent clinical need. Recent advances demonstrated that targeting senescence and autophagy in chondrocytes might be…
Abstract Number: 2003 • ACR Convergence 2024
Cumulative Incidence of Immune Checkpoint Inhibitor-Induced Inflammatory Arthritis in Lung Cancer Patients with and Without Hip Osteoarthritis and Impacts on Survival
Laura Cappelli¹, Shadpour Demehri¹, Joseph Murray¹, Julie Brahmer¹, Elena Ghotbi¹, Durrant Barasa¹, Clifton Bingham² and Ami Shah³, ¹Johns Hopkins School of Medicine, Baltimore, MD, ²Johns Hopkins University, Baltimore, MD, ³Division of Rheumatology, Johns Hopkins University, Ellicott City, MD
Background/Purpose: Rheumatologists are increasingly called upon to manage patients with inflammatory arthritis (IA) due to immune checkpoint inhibitor (ICI) therapy. The pathogenesis of ICI-IA is…
Abstract Number: 2101 • ACR Convergence 2024
Patient Characteristics Associated with Objectively-Assessed Physical Activity in Veterans with Knee Osteoarthritis
Hannah Brubeck¹, David Azizi², Sarah Wetzel², Marianna Olave², Rachel Gillcrist³, Bridget Kramer⁴, Bibiana Ateh⁵, Daniel White⁶, Carla Scanzello⁷, Tuhina Neogi⁸, Alexis Ogdie⁹, Bryant England⁴, Mercedes Quinones¹⁰, Katherine Wysham¹¹ and Joshua Baker⁷, ¹VA Puget Sound Health Care System, Seattle, WA, ²Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, ³Corporal Michael J. Crescenz VA Medical Center, Philadelphia, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵Washington DC VA Medical Center, Washington, DC, ⁶University of Delaware, Newark, DE, ⁷University of Pennsylvania, Philadelphia, PA, ⁸Boston University Chobanian & Avedisian School of Medicine, Boston, MA, ⁹Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ¹⁰Washington DC VA Medical Center, Bethesda, MD, ¹¹VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA
Background/Purpose: Despite strong recommendations for physical activity in knee osteoarthritis (KOA) clinical practice guidelines, only a small fraction of those with KOA meet guidelines for…
Abstract Number: PP10 • ACR Convergence 2024
Walking Away from Arthritis Pain: Exercise Helped Me Manage Sarcoidosis and Osteoarthritis Physically and Emotionally
Bridget Kelly, Hospital for Special Surgery, Rockville Centre, NY
Background/Purpose: In 2004, we moved to a new home with 2 small children, when I started experiencing terrible joint pain. For 2 years I was…
Abstract Number: 0364 • ACR Convergence 2024
Exploring 24-Hour Temporal Trends in Symptoms and Treatment of Rheumatic Disease Through Google Search Trends
Insa Mannstadt¹, J. Alex B. Gibbons² and Bella Mehta³, ¹Columbia University VP&S, New York, NY, ²Columbia University Vagelos College of Physicians & Surgeons, New York, NY, ³Hospital for Special Surgery, Weill Cornell Medicine, New York, NY
Background/Purpose: Symptoms of rheumatic diseases such as joint stiffness and pain are known to peak in the early morning hours. In the digital age, tracking…
Abstract Number: 1003 • ACR Convergence 2024
Association Between Metabolic Markers and Knee Osteoarthritis: A Cross-sectional Study Using the Korea National Health and Nutrition Examination Survey 2009 to 2013
Junyong Park, Minkook Son, Sang Yeob Lee, Won Tae Chung and Sung Won Lee, Dong-A University College of Medicine, Busan, Republic of Korea
Background/Purpose: Low-grade, prolonged inflammation of involved joint is characteristic of osteoarthritis (OA) pathogenesis. Thus susceptibility to inflammation has been considered as a risk factor for…
Abstract Number: 1190 • ACR Convergence 2024
Cross-sectional Associations Among Sonographic and Radiographic Features and Symptoms Scores in a Population-Based Cohort
Katherine Yates¹, Carolina Alvarez², Sahar Sawani³, Liubov Arbeeva⁴, Todd Schwartz⁵, Serena Savage-Guin⁶, Jordan Renner⁷, Catherine Bakewell⁸, Minna Kohler⁹, Janice Lin¹⁰, Jonathan Samuels¹¹ and Amanda Nelson³, ¹University of North Carolina Medical Center, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Miami, FL, ³University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴University of North Carolina, Chapel Hill, Carrboro, NC, ⁵University of North Carolina-Chapel Hill, Chapel Hill, NC, ⁶Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill,, Chapel Hill, NC, ⁷Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁸Intermountain Healthcare, Salt Lake City, UT, ⁹Massachusetts General Hospital, Boston, MA, ¹⁰Stanford University, Palo Alto, CA, ¹¹NYU Langone, Rye Brook, NY
Background/Purpose: Ultrasound (US) allows for visualization of features of knee osteoarthritis (KOA) including osteophytes, meniscal extrusion, synovitis, and cartilage damage. The current analysis aimed to…
Abstract Number: 1206 • ACR Convergence 2024
Association of Effusion-synovitis on Knee Pain in Early and Later-stage Knee Osteoarthritis
Lindsey MacFarlane¹, Mike Paskewicz², Jamie Collins² and Jeffrey Katz², ¹Brigham and Women's Hospital, Hanover, NH, ²Brigham and Women's Hospital, Boston, MA
Background/Purpose: Pain in knee osteoarthritis (OA) is associated with structural features including effusion-synovitis (E-S) and radiographic severity. Prior studies show a cross-sectional association between larger…
Abstract Number: 1656 • ACR Convergence 2024
Loss of Nr4a1 Expression Protects Cartilage During Post-traumatic Osteoarthritis
Katherine Escalera-Rivera, Jennifer Jonason and Jennifer Anolik, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Osteoarthritis (OA) is a complex disease involving pathological processes in joint tissues such as the cartilage and synovium. Cartilage is degraded by matrix metalloproteinases…
Abstract Number: 2061 • ACR Convergence 2024
Associations Between Intramyocellular Lipid and Muscle Function in Patients with Osteoarthritis
Rachel Gillcrist¹, Marianna Olave², Ryan Armbruster³ and Joshua Baker⁴, ¹Corporal Michael J. Crescenz VA Medical Center, Philadelphia, ²Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, ³University of Pennsylvania, Philadelphia, ⁴Department of Medicine, Perelman School of Medicine University of Pennsylvania, Philadelphia, PA
Background/Purpose: Intramyocellular lipids (IMCL), stored within lipid droplets in skeletal muscle cells, serve as an important metabolic fuel source during exercise. Endurance athletes have demonstrated higher…

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