Abstracts tagged "Osteoarthritis"

Abstract Number: 101 • 2013 ACR/ARHP Annual Meeting
Trends In Prescription Of Opioids From 2003-2009 In Persons With Knee Osteoarthritis
Elizabeth Wright¹, Jeffrey N. Katz², Stanley Abrams³, Daniel H. Solomon⁴ and Elena Losina⁵, ¹Orthopedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ²Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA, ³Orthopedics and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ⁴Division of Pharmacoepidemiology, Harvard Medical School, Brigham and Women's Hospital, Division of Rheumatology, Division of Pharmacoepidemiology, Boston, MA, ⁵Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Osteoarthritis (OA) of the knee is a painful condition affecting ~13% of persons >65 years of age. OA is often accompanied by comorbidities. Effective…
Abstract Number: 2668 • 2013 ACR/ARHP Annual Meeting
A Randomized, Double-Blind, Dose Ranging Study Comparing FX006, An Intra-Articular (IA) Sustained-Release Formulation Of Triamcinolone Acetonide (TCA), To An Approved Injectable Suspension Of TCA In Patients With Osteoarthritis (OA) Of The Knee
Neil Bodick¹, Joelle Lufkin¹, Christina Willwerth¹, Pierre Lachance², Gregory Jasey³, Anil Gupta⁴, Anthony Chris⁵, Marc Russo⁶, Michael O'Mahony⁷, Sam Henein⁸, Louise Murdoch⁹, Ferdinandus de Looze¹⁰, David Hunter¹¹ and Michael Clayman¹, ¹Flexion Therapeutics, Burlington, MA, ²Clinique St-Louis (Recherche) Inc, Quebec, QC, Canada, ³North Walkerville Orthopaedic Associates, Windsor, ON, Canada, ⁴Anil K. Gupta Medicine Professional Corporation, Toronto, ON, Canada, ⁵Aim Health Group, Waterloo, ON, Canada, ⁶Hunter Clinical Research, Broadmeadow, Australia, ⁷London Road Diagnostic Clinic and Medical Centre, Sarnia, ON, Canada, ⁸SKDS Research Inc., Newmarket, ON, Canada, ⁹Emeritus Research, Malvern East, Australia, ¹⁰AusTrials Pty Limited, Sherwood, Australia, ¹¹Royal North Shore Hospital, St. Leonards, Australia
Background/Purpose: FX006 is a novel sustained-release formulation of TCA in poly(lactic-co-glycolic) acid microspheres intended to maintain therapeutic concentrations in the joint up to 3 months…
Abstract Number: 1719 • 2013 ACR/ARHP Annual Meeting
High Reliability Was Found for Ultrasound Scoring of Osteophytes in Patients With Hand Osteoarthritis Using An Atlas As Reference; An Omeract Initiative
Hilde B. Hammer¹, Alexander Mathiessen¹, Annamaria Iagnocco², Emilio Filippucci³, Frédérique Gandjbakhch⁴, Marion C. Kortekaas⁵, Ingrid Möller⁶, Esperanza Naredo⁷, Richard J. Wakefield⁸, Philippe Aegerter⁹ and Maria-Antonietta d'Agostino¹⁰, ¹Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Sapienza University of Rome, Rome, Italy, ³Clinica Reumatologica, Università Politecnica delle Marche, Ancona, Italy, ⁴Department of Rheumatology, APHP, Pitié Salpétrière Hospital, Universite Paris 6, Paris, France, ⁵Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁶Instituto Poal de Reumatologia, Barcelona, Spain, ⁷Rheumatology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain, ⁸NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds & Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁹Epidemiology, Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital,, Boulogne-Billancourt,, France, ¹⁰Rheumatology, Ambroise Paré Hospital, and Versailles Saint Quentin en Yvelines University, Boulogne-Billancourt, France
Background/Purpose: Ultrasound (US) is a sensitive method for detecting osteophytes (OP) in hand osteoarthritis (HOA). To improve the reliability of scoring OP, an US atlas…
Abstract Number: 86 • 2013 ACR/ARHP Annual Meeting
The Role Of Meniscal Cells In Osteoarthritis Calcification
Andrea Roberts¹, David Mauerhan² and Yubo Sun², ¹Orthopedic Biology Research, Carolinas Healthcare System, Charlotte, NC, ²Orthopaedic Surgery, Carolinas Medical Center, Charlotte, NC
Background/Purpose: Osteoarthritis (OA) is a disease that is characterized by the breakdown or loss of articular cartilage due to biomechanical and biochemical changes in the…
Abstract Number: 2315 • 2013 ACR/ARHP Annual Meeting
Reducing The Need For Total Knee Arthroplasty: The Experience Of a Multidisciplinary Osteoarthritis Clinic
Caroline Jones¹, Angelo Papachristos¹ and Laurence A. Rubin², ¹Physiotherapy, St Michael's Hospital, Toronto, ON, Canada, ²Rheumatology, St. Michael Hospital, Toronto, ON, Canada
Background/Purpose: St. Michael’s Hospital (SMH) is a tertiary care facility located in Toronto, serving a diverse social, economic and cultural urban population. In 2008, a…
Abstract Number: 1694 • 2013 ACR/ARHP Annual Meeting
A Randomised Trial Of A Brace For Patellofemoral Osteoarthritis Targeting Knee Pain and Bone Marrow Lesions
David T. Felson^1,2, Matthew J. Parkes¹, Andrew D. Gait³, Elizabeth J. Marjanovic³, Mark Lunt⁴, Charles E. Hutchinson⁵, Laura Forsythe⁶, Timothy F. Cootes³ and Michael Callaghan¹, ¹Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Imaging Sciences, School of Cancer & Enabling Sciences, University of Manchester, Manchester, United Kingdom, ⁴Arthritis Research UK Centre for Epidemiology, University of Manchester, Manchester, United Kingdom, ⁵Warwick Medical School, University of Warwick, Coventry, United Kingdom, ⁶Arthritis Research UK Epidemiology Unit, University of Manchester, Manchester, United Kingdom
Background/Purpose: Patellofemoral (PF) braces have been shown to increase contract area in this joint, decreasing focal stress and may also correct patellar malalignment. Bone marrow…
Abstract Number: 84 • 2013 ACR/ARHP Annual Meeting
New Formulation With Potential To Prevent and Treat Osteoporosis and Osteoarthritis
A. Torrent¹, E. Montell², J. Vergés¹, P. Dalmau³, R. Ruhí³, M.C. Carceller⁴, A. Blanco⁴, M.C. Terencio⁴, M.L. Ferrándiz⁴ and M.J. Alcaraz⁵, ¹Pre-Clinical R&D Area, Pharmascience Division, BIOIBERICA S.A., Barcelona, Spain, ²Pharmascience Division, BIOIBERICA S.A., Barcelona, Spain, ³Technological Extraction Dept, BIOIBERICA S.A., Palafolls, Spain, ⁴Department of Pharmacology and IDM, University of Valencia, Burjassot, Spain, ⁵University of Valencia, Burjasot, Valencia, Spain
Background/Purpose: Osteoarthritis (OA) is a multidimensional disease that affects all anatomical joint structures, particularly cartilage, synovium and subchondral bone. In turn, osteoporosis (OP) is a…
Abstract Number: 2254 • 2013 ACR/ARHP Annual Meeting
Complementary and Alternative Medicine in Rheumatoid Arthritis – Persistently High Use Over the Past Decade Despite Advent of Biologics
Dana DiRenzo^1,2, Haiyan Sun³, H. Lester Kirchner³ and Eric D. Newman⁴, ¹Rheumatology, Geisinger Medical Center, Danville, PA, ²Internal Medicine, University of Maryland Medical Center, Baltimore, MD, ³Geisinger Center for Health Research, Geisinger Health System, Danville, PA, ⁴Department of Rheumatology, Geisinger Health System, Danville, PA
Background/Purpose: Complementary and Alternative Medicine (CAM) is commonly used when traditional medicine cannot reliably alter the disease. Over the past decade, rheumatoid arthritis (RA) treatment…
Abstract Number: 1378 • 2013 ACR/ARHP Annual Meeting
Associations Of Periodontitis (PD) With Established Seropositive Rheumatoid Arthritis are Independent of Smoking and Other Risk Factors
Ted R. Mikuls¹, Jeffrey Payne², Fang Yu³, Geoffrey M. Thiele⁴, Richard J. Reynolds⁵, Grant W. Cannon⁶, Jeffrey Markt⁷, David McGowan⁸, Gail S. Kerr⁹, Robert Redman¹⁰, Andreas M. Reimold¹¹, Garth Griffiths¹², Mark Beatty², Shawneen Gonzalez², Debra Bergman¹³, Bartlett C. Hamilton III¹⁴, Alan R. Erickson¹ and James R. O'Dell¹⁵, ¹Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ²College of Dentistry, University of Nebraska Medical Center, Lincoln, NE, ³University of Nebraska Medical Center, Omaha, NE, ⁴Int Med/Sec of Rheum/Immun, Univ of Nebraska Med Ctr, Omaha, NE, ⁵Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁶Division of Rheumatology, Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁷Otol-Head and Neck Surgery, University of Nebraska Medical Center, Omaha, NE, ⁸Dentistry, George E. Wahlen VA Medical Center, Salt Lake City, UT, ⁹Rheumatology, Washington DC VAMC, Georgetown and Howard University, Washington, DC, ¹⁰Dentistry, Washington DC VA, Georgetown and Howard University, Washington, DC, ¹¹Rheumatology, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹²Dentistry, Dallas VA and University of Texas Southwestern, Dallas, TX, ¹³Internal Medicine, University of Nebraska Medical Center, Omaha, NE, ¹⁴University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, ¹⁵Dept of Internal Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Periodontitis (PD) has been proposed as a risk factor in RA. Reports have suggested that this association may be due to confounding from smoking…
Abstract Number: 97 • 2013 ACR/ARHP Annual Meeting
Incidence and Trend Of Osteoarthritis In An Administrative Database From British Columbia, Canada
M Mushfiqur Rahman^1,2, Jolanda Cibere^3,4, Charles H Goldsmith^2,5, Aslam H. Anis^6,7 and Jacek A. Kopec^1,8, ¹School of Population and Public Health, University of British Columbia, VANCOUVER, BC, Canada, ²Biostatistics, Arthritis Research Centre of Canada, Richmond, BC, Canada, ³Department of Medicine, University of British Columbia, VANCOUVER, BC, Canada, ⁴Division of Rheumatology, Arthritis Research Centre of Canada, Richmond, BC, Canada, ⁵Health Sciences, Simon Fraser University, Burnaby, BC, Canada, ⁶St. Paul's Hospital, Centre for Health Evaluation and Outcome Sciences, Vancouver, BC, Canada, ⁷School of Population and Public Health, University of British Columbia, Vancouver, BC, Canada, ⁸Arthritis Research Centre of Canada, Richmond, BC, Canada
Background/Purpose: Data on the incidence of osteoarthritis (OA) are limited and there is little information on the trend in incidence of OA over time. The…
Abstract Number: 2149 • 2013 ACR/ARHP Annual Meeting
Safety Of Lower-Dose Diclofenac Submicron Particle Capsules Dosed Up To 12 Weeks In Patients With Osteoarthritis
Clarence Young¹ and Marc C. Hochberg², ¹Iroko Pharmaceuticals, Philadelphia, PA, ²Medicine, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Osteoarthritis (OA) is the most common cause of disability in the US and is frequently managed with non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs, including diclofenac,…
Abstract Number: 1250 • 2013 ACR/ARHP Annual Meeting
Serological Markers Of Structural Integrity and Inflammation Is Associated With Pain In Osteoarthritis
Anne Sofie Siebuhr¹, Lars Arendt-Nielsen², Thomas Navndrup Eskehave³, Morten Asser Karsdal⁴, Kristian Kjaer Petersen⁵, Ole Simonsen⁶ and Anne C. Bay-Jensen⁷, ¹Cartilage Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, ²Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Center for Sensory-Motor Interaction, Aalborg, Denmark, ³Center for Clinical and Basic Research and C4Pain, Aalborg, Denmark, ⁴Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, ⁵Department of Health Science and Technology, Faculty of Medicine, Aalborg University, Denmark, Center for Sensory-Motor Interaction, Aalborg, Denmark, ⁶Frederikshavn Hospital, Frederikshavn, Denmark, ⁷Rheumatology, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark
Background/Purpose: Pain is associated with diagnosed osteoarthritis (OA), but little clinically association is found between joint integrity and the pain the individual patient experience. Peripheral…
Abstract Number: 99 • 2013 ACR/ARHP Annual Meeting
Twenty-First Century Prevalence Of Frequent Knee Pain, Radiographic, Symptomatic and Clinical Knee Osteoarthritis According to American College Of Rheumatology Criteria In Southern Sweden
Aleksandra Turkiewicz¹, Maria Gerhardsson de Verdier², Gunnar Engström³, Stefan Lohmander¹ and Martin Englund¹, ¹Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Astra Zeneca R&D Molndal, Molndal, Sweden, Molndal, Sweden, ³Dept of Cardiovascular epidemiology, Clinical Sciences, Lund University, Lund, Sweden
Background/Purpose: To provide current estimates of the prevalence of knee pain, radiographic, symptomatic, and clinical knee osteoarthritis (OA) in middle-aged and elderly in Sweden. Methods:…
Abstract Number: 2129 • 2013 ACR/ARHP Annual Meeting
The Diagnostic Utility Of Anterior Knee Pain and Pain With Activities In Identifying Knees With MRI-Detected Structural Damage In The Patellofemoral Joint: The Multicenter Osteoarthritis Study
Joshua J. Stefanik¹, Tuhina Neogi², Jingbo Niu², Neil A. Segal³, Cora E. Lewis⁴, Michael C. Nevitt⁵, Frank Roemer⁶, Ali Guermazi⁷ and David T. Felson⁸, ¹Clinical Epidemiology, Boston University, Boston, MA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, ⁴Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, ⁵Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁶Klinikum Augsburg, Augsburg, Germany, ⁷Boston University, Boston, MA, ⁸Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: It is widely thought that patellofemoral joint (PFJ) pathology, a source of symptoms in knee osteoarthritis (OA), can be identified using patient history and…
Abstract Number: 1075 • 2013 ACR/ARHP Annual Meeting
Patient Characteristics Associated With Insomnia and Sleep Apnea In Knee and Hip OA
Kelli D. Allen¹, Hayden B. Bosworth², Cynthia Coffman², Amy Jeffreys¹, Eugene Z. Oddone¹, William S. Yancy Jr.³ and Christi Ulmer⁴, ¹Health Services Research, Duke and Durham VA Medical Center, Durham, NC, ²Health Services Research, Durham VA Medical Center and Duke University Medical Center, Durham, NC, ³Health Services Research, Durham VA Medical Center, Durham, NC, ⁴Duke and Durham VA Medical Center & Psychiatry, Duke and Durham VA Medical Center, Durham, NC
Background/Purpose: There is increasing recognition that sleep quality is a key outcome among patients with osteoarthritis (OA), but little is known about how clinical or…

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