Abstracts tagged "Osteoarthritis"

Abstract Number: 99 • 2013 ACR/ARHP Annual Meeting
Twenty-First Century Prevalence Of Frequent Knee Pain, Radiographic, Symptomatic and Clinical Knee Osteoarthritis According to American College Of Rheumatology Criteria In Southern Sweden
Aleksandra Turkiewicz¹, Maria Gerhardsson de Verdier², Gunnar Engström³, Stefan Lohmander¹ and Martin Englund¹, ¹Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden, ²Astra Zeneca R&D Molndal, Molndal, Sweden, Molndal, Sweden, ³Dept of Cardiovascular epidemiology, Clinical Sciences, Lund University, Lund, Sweden
Background/Purpose: To provide current estimates of the prevalence of knee pain, radiographic, symptomatic, and clinical knee osteoarthritis (OA) in middle-aged and elderly in Sweden. Methods:…
Abstract Number: 2129 • 2013 ACR/ARHP Annual Meeting
The Diagnostic Utility Of Anterior Knee Pain and Pain With Activities In Identifying Knees With MRI-Detected Structural Damage In The Patellofemoral Joint: The Multicenter Osteoarthritis Study
Joshua J. Stefanik¹, Tuhina Neogi², Jingbo Niu², Neil A. Segal³, Cora E. Lewis⁴, Michael C. Nevitt⁵, Frank Roemer⁶, Ali Guermazi⁷ and David T. Felson⁸, ¹Clinical Epidemiology, Boston University, Boston, MA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Orthopaedics and Rehabilitation, University of Iowa, Iowa City, IA, ⁴Preventive Medicine, University of Alabama, Birmingham, Birmingham, AL, ⁵Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁶Klinikum Augsburg, Augsburg, Germany, ⁷Boston University, Boston, MA, ⁸Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: It is widely thought that patellofemoral joint (PFJ) pathology, a source of symptoms in knee osteoarthritis (OA), can be identified using patient history and…
Abstract Number: 1075 • 2013 ACR/ARHP Annual Meeting
Patient Characteristics Associated With Insomnia and Sleep Apnea In Knee and Hip OA
Kelli D. Allen¹, Hayden B. Bosworth², Cynthia Coffman², Amy Jeffreys¹, Eugene Z. Oddone¹, William S. Yancy Jr.³ and Christi Ulmer⁴, ¹Health Services Research, Duke and Durham VA Medical Center, Durham, NC, ²Health Services Research, Durham VA Medical Center and Duke University Medical Center, Durham, NC, ³Health Services Research, Durham VA Medical Center, Durham, NC, ⁴Duke and Durham VA Medical Center & Psychiatry, Duke and Durham VA Medical Center, Durham, NC
Background/Purpose: There is increasing recognition that sleep quality is a key outcome among patients with osteoarthritis (OA), but little is known about how clinical or…
Abstract Number: 46 • 2013 ACR/ARHP Annual Meeting
Alarmins S100A8/A9 Regulate Osteophyte Formation In Experimental Osteoarthritis With High Synovial Activation
Rik Schelbergen¹, Arjen B. Blom¹, Wouter de Munter¹, Annet W. Sloetjes², Thomas Vogl³, Johannes Roth⁴, Wim B. van den Berg⁵ and Peter L.E.M. van Lent¹, ¹Rheumatology Research & Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Experimental Rheumatology (272), Radboud university medical center, Nijmegen, Netherlands, ³Institute of Immunology, University of Muenster, Muenster, Germany, ⁴Immunology, Institute of Immunology University of Muenster, Muenster, Germany, ⁵Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Osteophytes are cartilage capped, bony outgrowths that limit joint movement and originate from the periosteum or from ligaments during osteoarthritis (OA). There is increasing…
Abstract Number: 2130 • 2013 ACR/ARHP Annual Meeting
Factors Associated With Two-Year Pain Experience Outcome In Knee Osteoarthritis
Jamie E. Rayahin¹, Joan S. Chmiel², Orit Almagor², Laura Belisle², Alison H. Chang³, Kirsten Moisio², Karen W. Hayes², Yunhui Zhang² and Leena Sharma², ¹University of Illinois, Chicago, Chicago, IL, ²Northwestern University, Chicago, IL, ³Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, IL
Background/Purpose: Few strategies to improve pain outcome in knee OA exist, in part because methods to evaluate this outcome are not established. ICOAP development…
Abstract Number: 1077 • 2013 ACR/ARHP Annual Meeting
Less Time Spent In Sedentary Behavior Is Associated With Better Future Physical Function: Objective Data From The Osteoarthritis Initiative
Jungwha Lee¹, Jing Song², Rowland W. Chang², Linda S. Ehrlich-Jones³, Pamela A. Semanik⁴, Min-Woong Sohn⁵ and Dorothy D. Dunlop², ¹Preventive Medicine, Northwestern University Medical School, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Research CROR, Rehabilitation Institute Chicago, Chicago, IL, ⁴Northwestern University, Chicago, IL, ⁵Institute for Public Health and Medicine, Northwestern University, Chicago, IL
Background/Purpose: Public health physical activity interventions often focus on increasing exercise but give limited attention to reducing sedentary behavior. This study examined whether objectively measured…
Abstract Number: 2132 • 2013 ACR/ARHP Annual Meeting
Short-Run Transitions In Pain States: Reflections Of Multiple Outcome Clinical Measures of Inadequate Pain Relief among Patients With Knee Osteoarthiritis
Stephanie Taylor¹, Christopher Black², Paul M. Peloso³, Philip G. Conaghan⁴, Leah Stokes², Mart A.F.J. van de Laar⁵, François Rannou⁶, Nigel K. Arden⁷ and Panagiotis Mavros², ¹Global Health Outcomes, Merck & Co., Inc., Whitehouse Station, NJ, ²Global Health Outcomes, Merck, Whitehouse Station, NJ, ³Clinical Research, Merck Sharp & Dohme Corp., Rahway, NJ, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Rheumatology, University of Twente & Medisch Spectrum Twente, Enschede, Netherlands, ⁶Physical Medicine and Rehabilitation Service, Paris-Descartes University, Cochin Hospital, Paris, France, ⁷NDORMS; MRC Lifecourse Epidemiology Unit, Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom
Background/Purpose: Despite the importance of pain management in osteoarthritis (OA), there has been limited evidence confirming the adequacy of measuring pain relief in clinical practice setting. The objective of…
Abstract Number: 982 • 2013 ACR/ARHP Annual Meeting
Preferred Strategies For Delivering Treatment Information To People With Rheumatoid Arthritis, Osteoarthritis and Osteoporosis
Maria A. Lopez-Olivo¹, Robert Volk², Maria Jibaja-Weiss³ and Maria E. Suarez-Almazor⁴, ¹General Internal Medicine, University of Texas. M.D Anderson Cancer Center, Houston, TX, ²General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX, ³Office of Outreach and Health Disparities, Baylor College of Medicine, Houston, TX, ⁴The Department of General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX
Background/Purpose: To explore the perceptions of people with rheumatoid arthritis (RA), osteoarthritis (OA), and osteoporosis (OP) regarding their preferred delivery methods for obtaining treatment information…
Abstract Number: 2135 • 2013 ACR/ARHP Annual Meeting
Musculoskeletal Pain Explains Differences In Function At Time Of Surgery In Black TKR and THR Patients
Anthony Porter¹, Wenjun Li², Leslie R. Harrold¹, Milagros Rosal³, Philip Noble⁴, David Ayers², Patricia D. Franklin² and Jeroan Allison⁵, ¹University of Massachusetts Medical School, Worcester, MA, ²Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ³Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, MA, ⁴Baylor College of Medicine, Houston, TX, ⁵Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA
Background/Purpose: The existence of racial disparities in total knee (TKR) and total hip (THR) replacement outcomes is well established but not well understood. The burden…
Abstract Number: 771 • 2013 ACR/ARHP Annual Meeting
The S100A9 Inhibitor Paquinimod (ABR-215757) Reduces Synovial Activation, Osteophyte Formation and Cartilage Damage In Experimental Osteoarthritis
Rik Schelbergen¹, Arjen B. Blom¹, Tomas Leanderson², Helena Eriksson³, Wim B. van den Berg⁴ and Peter L.E.M. van Lent¹, ¹Rheumatology Research & Advanced Therapeutics, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ²Immunology Group, Lund University, Lund, Sweden, ³BioScience, Active Biotech AB, Lund, Sweden, ⁴Rheumatology Research and Advanced Therapeutics, Department of Rheumatology, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands
Background/Purpose: Synovial activation is present in a large subset of osteoarthritis (OA) patients and it is thought to play an important role in the development…
Abstract Number: 2136 • 2013 ACR/ARHP Annual Meeting
Does Functional Gain and Pain Relief After TKR and THR Differ By Patient Obese Status?
Wenjun Li¹, Leslie R. Harrold², Jeroan Allison³, Courtland Lewis⁴, Thomas Bowen⁵, Patricia D. Franklin¹ and David Ayers¹, ¹Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ²University of Massachusetts Medical School, Worcester, MA, ³Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, ⁴Hartford Hospital, Hartford, CT, ⁵Geisinger, Danville, PA
Background/Purpose: Obesity is an important predictor of functional status and pain after total knee (TKR) and total hip (THR) replacement. However, variations in pre-post TKR…
Abstract Number: 778 • 2013 ACR/ARHP Annual Meeting
Relationship of Meeting Physical Activity Guidelines and Quality Adjusted Life Years
Kai Sun¹, Jing Song², Larry Manheim³, C. Kent Kwoh⁴, Rowland W. Chang², Pamela A. Semanik⁵, Dorothy D. Dunlop² and Charles Eaton⁶, ¹Medicine, Northwestern University, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Institute Healthcare Studies, Northwestern University, Chicago, IL, ⁴School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, ⁵Northwestern University, Chicago, IL, ⁶Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI
Background/Purpose: Regular physical activity is associated with reduced chronic disease burden and mortality. Recognizing the importance of physical activity, there are US federal guidelines for…
Abstract Number: 2137 • 2013 ACR/ARHP Annual Meeting
Important Predictors Of Patient-Reported Outcomes After TKR and THR Are Not Included In Risk Models Based On Administrative Data
Patricia D. Franklin¹, Leslie R. Harrold², Wenjun Li¹, Jeroan Allison³, David Ayers¹ and Courtland Lewis⁴, ¹Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ²University of Massachusetts Medical School, Worcester, MA, ³Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, ⁴Hartford Hospital, Hartford, CT
Background/Purpose: Because total knee (TKR) and total hip (THR) replacement surgery is performed to relieve pain and improve physical function in patients with advanced arthritis,…
Abstract Number: 767 • 2013 ACR/ARHP Annual Meeting
Zinc Finger Protein ZCCHC6 Is Highly Expressed In Osteoarthritic Cartilage and Regulate The Expression Of Interleukin-6 In Human Chondrocytes
Nahid Akhtar, Ahmad Arida and Tariq M. Haqqi, Anatomy & Neurobiology, North East Ohio Medical University, Rootstown, OH
Background/Purpose: Interleukin-1β (IL-1β) is the major cytokine involved in cartilage catabolism in osteoarthritis(OA) and induces the expression of pro-inflammatory cytokine IL-6. Members of cytoplasmic RNA…
Abstract Number: 2109 • 2013 ACR/ARHP Annual Meeting
Quality Indicators For Physical Therapy Management In Hip and Knee Osteoarthritis and Rheumatoid Arthritis
Wilfred FH Peter^1,2, Emalie Hurkmans³, Philip van der Wees⁴, Erik Hendriks⁵, Rob de Bie⁵, Leti van Bodegom-Vos⁶ and Theodora P.M. Vliet Vlieland⁷, ¹Departmentof Orthopaedics, Leiden University Medical Center, Leiden, Netherlands, ²Amsterdam Rehabilitation Research Center, Reade, centre for rehabilitation and rheumatology, Amsterdam, Netherlands, ³Section Physiotherapy, University of Applied Sciences, Vienna, Austria, ⁴IQ Healthcare, Radboud University, Nijmegen, Netherlands, ⁵Centre for Evidence Based Physiotherapy, University of Maastricht, Maastricht, Netherlands, ⁶Department of Medical Decision Making, Leiden University Medical Center, Leiden, Netherlands, ⁷Department of Orthopaedics, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Physical therapy is recommended in several guidelines on the management of osteoarthritis and rheumatoid arthritis. Currently, no specific quality indicators for physical therapy in…

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