Abstracts tagged "Osteoarthritis"

Abstract Number: 2388 • 2015 ACR/ARHP Annual Meeting
Variations in Hip Morphology Are Associated with Hip Symptoms: Preliminary Results from a Large Community-Based Cohort
Amanda E. Nelson¹, Jamie L. Stiller¹, Xiaoyan A. Shi^1,2, Jordan B. Renner³, Todd A. Schwartz⁴, Nigel K Arden⁵ and Joanne M. Jordan¹, ¹Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, ²SAS Institute, Inc, Cary, NC, ³Radiology, University of North Carolina, Chapel Hill, NC, ⁴School of Nursing, University of North Carolina, Chapel Hill, NC, ⁵Oxford NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom
Background/Purpose: Alterations in hip morphology, such as femoroacetabular impingement, have been associated with incident hip OA and total hip replacement (THR), but associations of these…
Abstract Number: 452 • 2015 ACR/ARHP Annual Meeting
Associations Between Arthritis Patient, Disease-Specific and Provider Characteristics and Medication Information Source Use
Lorie Geryk¹, Susan J. Blalock², Robert DeVellis³, Joanne M. Jordan³ and Delesha Carpenter⁴, ¹Division of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, Chapel Hill, NC, ²Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, ⁴Division of Pharmaceutical Outcomes and Policy, University of North Carolina Eshelman School of Pharmacy, Asheville, NC
Background/Purpose: Few studies have described how patient, disease-specific, and provider factors are associated with medication information source use among arthritis patients. We address this research…
Abstract Number: 2394 • 2015 ACR/ARHP Annual Meeting
B-Flow Imaging of Synovial Tissue in Osteoarthritis
Ralf G. Thiele¹, Allen P. Anandarajah² and Christopher T. Ritchlin³, ¹University of Rochester Medical Center, Rochester, NY, ²Dept of Rheumatology, Univ of Rochester Medical Ctr, Rochester, NY, ³Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Development of disease modifying medication for osteoarthritis (OA) is desirable, but the target tissue of such treatment remains unclear. We have previously shown that…
Abstract Number: 534 • 2015 ACR/ARHP Annual Meeting
Antibodies to Malondialdehyde-Acetaldehyde Adducts Are Highly Expressed in Rheumatoid Arthritis Synovial Fluid
Rafid Rahman¹, Geoffrey M. Thiele², Andy Hollins³, Michael J. Duryee¹, Daniel Anderson³, Bartlett Hamilton⁴, Kaleb Michaud⁵, Lynell W. Klassen⁶ and Ted R. Mikuls³, ¹Internal Medicine Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE, ³University of Nebraska Medical Center, Omaha, NE, ⁴University of Nebraska Medical Center and Omaha VA Medical Center, Omaha, NE, ⁵Rheumatology & Immunology, University of Nebraska Medical Center and National Data Base for Rheumatic Diseases, Omaha, NE, ⁶Dept of Internal Medicine, Omaha VA Medical Center and University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Malondialdehyde-acetaldehyde (MAA) adducts are expressed in synovial tissues in rheumatoid arthritis (RA). Post-translational MAA modifications are pro-inflammatory, promoting robust anti-MAA antibody responses that…
Abstract Number: 2407 • 2015 ACR/ARHP Annual Meeting
Comparison of Knee Osteoarthritis Treatment in the Non-Obese Versus Obese Populations Across Different Medical Specialties
Kelly Forrester¹, Farah Taufiq¹ and Jonathan Samuels^2,3, ¹NYU Langone Medical Center, New York, NY, ²Rheumatology, NYU - Hospital for Joint Diseases, New York, NY, ³Rheumatology, NYU Langone Medical Center, New York, NY
Background/Purpose: Knee osteoarthritis (KOA) in the obese population is underdiagnosed and routinely undertreated, as providers often attribute pain to excess weight without considering articular…
Abstract Number: 897 • 2015 ACR/ARHP Annual Meeting
Intra-Articular Corticosteroids Are Safe and Have No Major Effect on Structural Progression of Synovitic Knee OA: A 2-Year Randomized Controlled Trial of 3-Monthly Triamcinolone Hexacetonide
Jeffrey Driban¹, Michael P. Lavalley², Lori Lyn Price³, William F. Harvey⁴ and Timothy E. McAlindon⁴, ¹Tufts Medical Center, Boston, MA, ²Biostatistics, Boston University, Boston, MA, ³Clinical Care Research, Tufts Medical Center, Boston, MA, ⁴Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Synovitis is common in knees with OA, and is associated with structural progression. Intra-articular corticosteroids are widely used and could reduce knee OA cartilage…
Abstract Number: 2409 • 2015 ACR/ARHP Annual Meeting
Factors Associated with Physical Therapy Use in Osteoarthritis of the Knee: Results from a Population-Based Study
Sicong Huang¹, Eric C. Sayre² and Jolanda Cibere^1,2, ¹Department of Medicine, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Canada, Richmond, BC, Canada
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis. Physical therapy (PT) has previously been demonstrated to benefit patients with osteoarthritis, especially with early…
Abstract Number: 1291 • 2014 ACR/ARHP Annual Meeting
Relationships Between Inflammation, Disease Severity and Synovial Fluid Calcium Crystals Detected By Scanning Electronic Microscopy in Early Osteoarthritis
Paola Frallonardo¹, Francesca Oliviero¹, Luca Peruzzo², Leonardo Tauro³, Anna Scanu¹, Mariagrazia Lorenzin¹, Augusta Ortolan¹, Leonardo Punzi⁴ and Roberta Ramonda¹, ¹Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, ²Institute for Geosciences and Earth Resources IGG-CNR, Padova, Italy, ³Department of Geosciences, University of Padova, Padova, Italy, ⁴Department of Medicine - DIMED, University of Padova, Padova, Italy
Background/Purpose The presence of calcium crystals (CC) in synovial fluid (SF) of osteoarthritis (OA) is a well known and frequent feature (1). However, their role…
Abstract Number: 108 • 2014 ACR/ARHP Annual Meeting
Patient Reported Outcomes Following Total Knee Arthroplasty in Rheumatoid Arthritis and Osteoarthritis
Anand Dusad¹, Sofia Pedro², Kevin Garvin³, Curtis Hartman⁴, James O'Dell⁵, Ted R. Mikuls⁵ and Kaleb Michaud⁶, ¹Rheumatology, University of Nebraska Medical Center, Omaha, NE, ²National Data Bank for Rheumatic Diseases, Wichita, KS, ³Orthopaedic Surgery, University of Nebraska Medical Center, Omaha, NE, ⁴Orthopaedic Surgery and Rehabilitation, University of Nebraska Medical Center, Omaha, NE, ⁵University of Nebraska Medical Center, Omaha, NE, ⁶University of Nebraska Medical Center and National Data Bank, Omaha, NE
Background/Purpose: Due to the progressive and debilitating nature of knee arthritis, total knee arthroplasty (TKA) is the ultimate outcome. TKA is an effective surgical intervention…
Abstract Number: 1284 • 2014 ACR/ARHP Annual Meeting
Sensitivity to Change of Patient Preference Outcome Measures for Pain in Trials of Patients with Knee Osteoarthritis
Matthew J. Parkes¹, Michael J. Callaghan¹, Terence W. O'Neill¹ and David T. Felson^1,2, ¹Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose A variety of pain and function instruments are often measured in osteoarthritis (OA) clinical trials. Instruments with maximal sensitivity to change are preferred as the…
Abstract Number: 76 • 2014 ACR/ARHP Annual Meeting
Identification of Synovial Genes and Pathways Associated with Disease Progression in a Cohort of Early Symptomatic Osteoarthritis Patients Using a Transcriptomic Approach
Arjen B. Blom¹, Peter L. van Lent¹, Martijn H. van den Bosch², Hans Cats³, Frank H.J. van den Hoogen⁴, Floris P.J.G. Lafeber⁵, Wim B. van den Berg¹ and Peter M. van der Kraan¹, ¹Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Experimental Rheumatology (272), Radboud university medical center, Nijmegen, Netherlands, ³Hengstdal 3, Sint Maartenskliniek, Ubbergen, Netherlands, ⁴Rheumatology, Rheumatology Centre Sint Maartenskliniek and Radboud university medical center, Ubbergen (Nijmegen), Netherlands, ⁵Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands
Background/Purpose: If and how the synovial activation that is observed in over 50% of osteoarthritis (OA) patients contributes to irreversible joint pathology, is not known.…
Abstract Number: 1285 • 2014 ACR/ARHP Annual Meeting
Prevalence of Risk Factors for Gastrointestinal Side Effects of Drugs for the Treatment of Pain in Rheumatic Diseases and the Provision of Gastroprotective Treatment – Results of a Large Non-Intervention Study
Gustavo Citera¹, Edgardo Smecuol², Alberto Millán³, Manuel Robles⁴ and Ruben Mantilla⁵, ¹Universidad de Buenos Aires, Buenos Aires, Argentina, ²Hospital Municipal de Gastroenterología, Buenos Aires, Argentina, ³Hospital Universitario de Caracas, Caracas, Venezuela, ⁴Centro Médico Toluca, Toluca, Mexico, ⁵Clínica de Artritis y Rehabilitación (CAYRE), Bogota, Colombia
Background/Purpose: Non-steroidal anti-inflammatory drugs (NSAIDs) are the long established first-line treatment for the management of pain associated with rheumatic diseases but carry a risk of…
Abstract Number: 68 • 2014 ACR/ARHP Annual Meeting
Physical Inactivity to Activity Associated with Less Decline in Physical Function
Abigail Gilbert¹, Jing Song², Pamela A. Semanik³, Rowland W. Chang⁴ and Dorothy D. Dunlop², ¹Rheumatology, Northwestern University, Chicago, IL, ²Northwestern University Feinberg School of Medicine, Chicago, IL, ³Northwestern University, Chicago, IL, ⁴Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Regular physical activity has been demonstrated to improve quality of life for adults with chronic disease including osteoarthritis. Despite these benefits, half of adults…
Abstract Number: 2969 • 2014 ACR/ARHP Annual Meeting
Mortality after Knee Replacement Surgery for Osteoarthritis in a Population-Based Propensity-Score Matched Cohort
Devyani Misra¹, Tuhina Neogi², Na Lu³, David T. Felson³, Thomas Einhorn⁴, Hyon K. Choi⁵, Jessica Maxwell⁶ and Yuqing Zhang³, ¹Rheumatology, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Boston University School of Medicine, Boston, MA, ⁴Orthopedics, Boston University School of Medicine, Boston, MA, ⁵Division of Rheumatology, Allergy, and Immunology Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁶Physical Therapy & Athletic Training, Boston University, Boston, MA
Background/Purpose : Knee replacement (KR) surgery for osteoarthritis (OA) provides improvement in symptoms and function. Whether these improvements translate into survival benefit has been unclear,…
Abstract Number: 1088 • 2014 ACR/ARHP Annual Meeting
Socioeconomic Disparities in Health Outcomes Among Individuals with, or at Risk for, Osteoarthritis from the United States: Data from the Osteoarthritis Initiative
Antoine A. Baldassari¹, Todd Schwartz¹, Rebecca J. Cleveland¹, Joanne M. Jordan² and Leigh F. Callahan³, ¹Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²University of North Carolina Dept of Epidemiology, Chapel Hill, NC, ³Thurston Arthritis Res Ctr, University of North Carolina, Chapel Hill, NC
Background/Purpose Socioeconomic disparities in health outcomes among people with osteoarthritis are well documented, with some key limitations: existing studies limit their analyses to few outcome…

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