Abstract Number: 953 • 2015 ACR/ARHP Annual Meeting
Effectiveness of a Progressive Resistence Strength Programme on Hand Osteoarthritis: A Randomized Crontrolled Trial
Background/Purpose: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF)…Abstract Number: 2617 • 2015 ACR/ARHP Annual Meeting
Serum 14-3-3eta Protein Elevation in Osteoarthritis Suggests Misclassification or Concurrent Inflammatory Arthritis
Background/Purpose: Tissue distribution of the chaperonin 14-3-3η (eta) is limited to synovial tissue and brain. Synovium releases proinflammatory 14-3-3η into synovial fluid and serum in…Abstract Number: 1150 • 2015 ACR/ARHP Annual Meeting
Novel Chitosan Hydrogels for the Treatment of Osteoarthritis: Mechanical Support, Lubrication and Prevention of Cartilage Degradation in a Rabbit Model of Osteoarthritis
Background/Purpose: Chitosan, a glucosamine polysaccharide, is a good candidate for viscosupplementation in OA joints. Herein, we report the physico-chemical properties and the effects of an…Abstract Number: 3086 • 2015 ACR/ARHP Annual Meeting
The Same Multidimensional Patient Health Assessment Questionnaire Used to Assess RAPID3 in Rheumatoid Arthritis, Osteoarthritis and Other Rheumatic Diseases Can Provide Quantitative Clues to Recognize and Document Comorbid Fibromyalgia
Background/Purpose: An MDHAQ/RAPID3 (Multidimensional Health Assessment Questionnaire/Routine Assessment of Patient Index Data) is a 2 sided, 1 page questionnaire which is completed by patients in…Abstract Number: 2947 • 2014 ACR/ARHP Annual Meeting
Adenosine a2A Receptor As a Potential New Therapeutic Target for the Prevention/Treatment of Osteoarthritis
Background/Purpose Osteoarthritis results from trauma, mechanical factors or metabolic changes in bone and cartilage. Adenosine, acting via the A2AR, inhibits inflammation and plays a critical…Abstract Number: 1021 • 2014 ACR/ARHP Annual Meeting
Transthyretin and Amyloid in Cartilage Aging and Osteoarthritis
Background/Purpose Deposition of amyloid is a common aging-associated phenomenon and a key factor in the pathogenesis of several aging-related diseases. Osteoarthritis is the most prevalent…Abstract Number: 2439 • 2014 ACR/ARHP Annual Meeting
Knee Joint Pathology in Patients with Rheumatoid Arthritis and Osteoarthritis Using a Validated Ultrasound Scoring System: A Cross Sectional Study
Background/Purpose Ultrasound (US) signs of inflammation in joints are synovial hypertrophy, effusion, and Doppler activity (increased perfusion), which have been demonstrated in both osteoarthritis (OA)…Abstract Number: 977 • 2014 ACR/ARHP Annual Meeting
Randomized Clinical Trial of a Patient and Provider Intervention for Managing Osteoarthritis in Veterans
Background/Purpose: Adequate management of osteoarthritis (OA) requires both medical and behavioral strategies. However, some recommended therapies are under-utilized in clinical settings, and there is low…Abstract Number: 2337 • 2014 ACR/ARHP Annual Meeting
The Cost and Effectiveness of Various Recruitment Strategies in a Mind Body Clinical Trial Among Older Adults with Knee Osteoarthritis
Background/Purpose : Recruitment and adherence are important and challenging factors that can determine the success of a clinical trial. Mind body therapies are an emerging and…Abstract Number: 978 • 2014 ACR/ARHP Annual Meeting
Socioeconomic Status Measures Are Associated with Increasing Pain, Stiffness and Physical Function Among Individuals with Knee and Hip Osteoarthritis
Background/Purpose The determinants of disability progression (DP) among those with knee and/or hip osteoarthritis (OA) are not well known. Our aim was to explore whether…Abstract Number: 2233 • 2014 ACR/ARHP Annual Meeting
A PHASE 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy Study of Apremilast (CC-10004) in Subjects with Erosive Hand Osteoarthritis
Background/Purpose We report on a phase II, multicenter, randomized, double-blind, placebo-controlled, efficacy and safety study in subjects with erosive hand osteoarthritis. Subjects must have had…Abstract Number: 922 • 2014 ACR/ARHP Annual Meeting
A Potential Role for TLR4 Activation in Osteoarthritis Associated Pain
Background/Purpose - Damage associated molecular patterns (DAMPs) result from cellular stress and extracellular matrix breakdown. They may contribute to osteoarthritis (OA) pathogenesis by promoting synovitis…Abstract Number: 2237 • 2014 ACR/ARHP Annual Meeting
Interleukin-1 Dual-Variable Domain Immunoglobulin Reduces Multiple Inflammatory Markers in Knee Osteoarthritis Patients
Background/Purpose: Osteoarthritis (OA) may comprise multiple phenotypes, one of which is inflammation-driven OA. Consequently, a selected subpopulation of OA patients may benefit from optimally targeted…Abstract Number: 257 • 2014 ACR/ARHP Annual Meeting
Quality of Life Assessment of Adults Patients with X-Linked Hypophosphoremia
Background/Purpose: X-Linked Hypophosphatemia (XLH) is the most common form of heritable rickets. Although disease severity is variable, adults with XLH may suffer from skeletal symptoms…Abstract Number: 2243 • 2014 ACR/ARHP Annual Meeting
Comparison Between Two Diclofenac Diethylamine Gel Formulations, 1.16% Vs 2.32%: Is It Only Increasing the Strength of the Active Ingredient Enough?
Background/Purpose Topically applied non-steroidal anti-inflammatory drugs (NSAIDs) can produce clinically effective drug concentrations at a peripheral site, but with low systemic concentrations and thus a…
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