ACR Meeting Abstracts

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Abstracts tagged "Osteoarthritis"

  • Abstract Number: 1635 • ACR Convergence 2020

    Profile of Topical Diclofenac Sodium Gel 1% (Voltaren®) Users in a United States Longitudinal Electronic Health Records Database

    Amy Kenneally1, Frédérique Bariguian2, Richard Petruschke1, Arlene Tave3, Jess Edison4, Nicholas M. Sicignano5 and Francis Barbone1, 1GSK Consumer Healthcare, Warren, NJ, 2GSK Consumer Healthcare S.A., Nyon, Switzerland, 3PharmaLex US Corporation, Fairfax, VA, 4Walter Reed National Military Medical Center, Bethesda, 5Health ResearchTx LLC., Prevose, PA

    Background/Purpose: Diclofenac sodium gel 1% (DSG), a topical non-steroidal anti-inflammatory drug (NSAID), is effective for the relief of osteoarthritis (OA) pain in the elbows, wrists,…
  • Abstract Number: 1655 • ACR Convergence 2020

    Pain Reduction Post Total Knee Replacement in Opioid Users and Non-users

    Lindsey MacFarlane1, Yinzhu Jin1, Yvonne Lee2, Joyce Lii3, Jeffrey Katz4, Patricia Franklin5 and Seoyoung Kim1, 1Brigham and Women's Hospital, Boston, MA, 2Northwestern University Feinberg School of Medicine, Chicago, IL, 3Brigham and Women's Hospital, Boston, 4Harvard Medical School / The Orthopaedic and Arthritis Center for Outcomes Research (OrACORe) at Brigham and Women's Hospital, Boston, MA, 5Northwestern University, Chicago

    Background/Purpose: End-stage knee osteoarthritis (OA) is often managed with opioids and total knee replacement (TKR). Studies ascertaining opioid use via record review are conflicting as…
  • Abstract Number: 0130 • ACR Convergence 2020

    The Prevalence of Osteoporosis in Individuals with Osteoarthritis: A Systematic Review

    Timothy Varghese1, Ali Ahmadi Pirshahid2, Dongkeun Kim2 and Yueyang Li2, 1Schulich School of Medicine & Dentistry, Richmond Hill, ON, Canada, 2Schulich School of Medicine & Dentistry, London, ON, Canada

    Background/Purpose: There is controversy regarding the relationship between osteoarthritis (OA) and osteoporosis (OP). While OA may be associated with increased bone mineral density (BMD) due…
  • Abstract Number: 0694 • ACR Convergence 2020

    Relationships Among Adherence and Patient Outcomes in a Cognitive Behavioral Plus Physical Activity Intervention for Older Adults with Osteoarthritis and Hypertension

    Xiaojun Shi1, Elizabeth Schlenk2 and Susan Sereika1, 1University of Pittsburgh School of Nursing, Pittsburgh, 2University of Pittsburgh School of Nursing, Pittsburgh, PA

    Background/Purpose: Osteoarthritis of the knee (OAK) affects nearly 14 million older adults and more than half are diagnosed with hypertension (HTN). Cognitive behavior therapy (CBT)…
  • Abstract Number: 0963 • ACR Convergence 2020

    Chronic Obstructive Pulmonary Disease Associated with Prolonged Opiate Use, Increased Short-Term Complications and the Need for Revision Surgery Following Total Knee Arthroplasty

    Jillian Glasser1, Nicholas Lemme2, Daniel Yang2, Edward Testa2, Alan Daniels3 and Valentin Antoci3, 1University Orthopedics Inc, East Providence, RI, 2Warren Alpert School of Medicine, Providence, RI, 3Warren Alpert School of Medicine, East Providence, RI

    Background/Purpose: Chronic obstructive pulmonary disease (COPD) is a condition which causes a substantial burden to patients, physicians, and the healthcare system at large. Medical comorbidities…
  • Abstract Number: 1114 • ACR Convergence 2020

    Longitudinally Assessed Structural Abnormalities on MRI and Relative Contributions to Risk of Incident Radiographic Knee Osteoarthritis over 10 Years of Follow-up

    C. Kent Kwoh1, Ali Guermazi2, Erin Ashbeck3, Chengcheng Hu3, Edward Bedrick3, Leena Sharma4, Charles Eaton5, Marc Hochberg6, Rebecca Jackson7, Timothy McAlindon8, Michael Nevitt9, Jane Cauley10 and Frank Roemer11, 1University of Arizona of Arizona Arthritis Center and Division of Rheumatology, College of Medicine, University of Arizona, Tucson, AZ, 2Boston University School of Medicine, Boston, MA, 3University of Arizona, Tucson, AZ, 4Northwestern University Feinberg School of Medicine, Chicago, IL, 5Department of Family Medicine and Epidemiology, Warren Alpert Medical School of Brown University,Department of Epidemiology, School of Public Health of Brown University, Providence, RI, 6University of Maryland School of Medicine, Baltimore, MD, 7Ohio State University, Columbus, OH, 8Tufts Medical Center, Boston, MA, 9University of California, San Francisco, San Francisco, CA, 10University of Pittsburgh, Pittsburgh, PA, 11Boston University School of Medicine, Boston, MA, and Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany

    Background/Purpose: MRI has identified joint tissues affected during knee OA development, though the relative importance of structures in the pathogenic process is unknown. Our objective…
  • Abstract Number: 1468 • ACR Convergence 2020

    The Association of Walking Speed from Short- and Standard-Distance Tests with Mortality Risk Among Adults with Radiographic Knee Osteoarthritis: Data from Johnston County Osteoarthritis Project, Osteoarthritis Initiative and Multicenter Osteoarthritis Study

    Hiral Master1, Tuhina Neogi2, Leigh Callahan3, Amanda Nelson4, Michael LaValley5, Rebecca Cleveland6, Yvonne Golightly7, Louise Thoma8, Yuqing Zhang9, Dana Voinier10, Meredith Christiansen11, Jason Jakiela10, Michael Nevitt12, Cora Lewis13, Laura Frey Law14 and Daniel White10, 1Vanderbilt University Medical Center, Nashville, TN, 2Boston University School of Medicine, Boston, MA, 3University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, 4University of North Carolina Chapel Hill, Chapel Hill, 5Boston University School of Public Health, Boston, MA, 6University of North Carolina, Chapel Hill, NC, 7University of North Carolina at Chapel Hill Dept of Epidemiology, Chapel Hill, NC, 8University of North Carolina at Chapel Hill, Chapel Hill, NC, 9Massachusetts General Hospital, Harvard Medical School, Boston, 10University of Delaware, Newark, DE, 11University of Delaware, New York, NY, 12University of California, San Francisco, San Francisco, CA, 13University of Alabama Birmingham, Birmingham, AL, 14University of Iowa, Iowa City, IA

    Background/Purpose: Patients with radiographic knee OA (rKOA) are at increased risk of mortality and walking difficulty may mediate this relation. Walking speed may be used…
  • Abstract Number: 1640 • ACR Convergence 2020

    Clinically Important Improvement in Osteoarthritis Pain at Week 16 After Subcutaneous Administration of Tanezumab: Pooled Analysis from International Studies

    Thomas Schnitzer1, Francis Berenbaum2, Philip G Conaghan3, Robert Dworkin4, Takaharu Yamabe5, Isabelle Davignon5, Stefan Wilhelm6, Erika Dragon7 and Lars Viktrup6, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2AP-HP, Hôpital Saint-Antoine, Service de Rhumatologie, Centre de Recherche Saint-Antoine, INSERM UMR_S 938,Sorbonne Université, Paris, 75012, France, Paris, France, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research Leeds Biomedical Research Centre, Leeds, United Kingdom, 4University of Rochester School of Medicine and Dentistry, Rochester, NY, 5Pfizer Inc, Groton, CT, 6Eli Lilly and Company, Indianapolis, IN, 7Pfizer Ltd, Budapest, Hungary

    Background/Purpose: Tanezumab is under investigation for the treatment of moderate to severe OA pain. As part of the phase 3 OA program, two randomized, placebo-controlled…
  • Abstract Number: 1656 • ACR Convergence 2020

    Knee OA Outcomes in Patients with Severe Obesity Following Bariatric Surgery or Total Knee Arthroplasty

    Jonathan Samuels1, Stephen Zak2, Ran Schwarzkopf2, Christine Ren-Fielding3, Manish Parikh4, Alex McLawhorn5, James Browne6, Peter Hallowell7, Brian Irving8, Craig Wood9, Christopher Still9 and Peter Benotti9, 1NYU Langone, Rye Brook, NY, 2NYU Langone Health, New York, NY, 3NYU Langone Health, New YOrk, 4Bellevue Hospital, New York, NY, 5Hospital for Special Surgeyr, New York, 6University of Virginia, Charlottesville, VA, 7University of Virginia, Charlottesville, 8Louisiana State University, Baton Rouge,, LA, 9Obesity institute at Geisinger, Danville

    Background/Purpose: High body mass index (BMI, kg/m2) is a modifiable risk factor that has been associated with the development and progression of osteoarthritis (OA) and…
  • Abstract Number: 0140 • ACR Convergence 2020

    Meaningful Within-Patient Change in WOMAC Domains in Patients with Moderate-To- Severe Osteoarthritis

    Philip G Conaghan1, Robert Dworkin2, Thomas Schnitzer3, Francis Berenbaum4, Andrew Bushmakin5, Joseph Cappelleri5, Lars Viktrup6 and Lucy Abraham7, 1Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and National Institute for Health Research Leeds Biomedical Research Centre, Leeds, United Kingdom, 2University of Rochester School of Medicine and Dentistry, Rochester, NY, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Sorbonne Universite�, Paris, France, 5Pfizer Inc, Groton, CT, 6Eli Lilly and Company, Indianapolis, IN, 7Pfizer Inc, Tadworth, United Kingdom

    Background/Purpose: The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a disease-specific measure of osteoarthritis (OA) symptoms (pain and stiffness) and functional impairment regularly…
  • Abstract Number: 0699 • ACR Convergence 2020

    Lumbar Spine Stenosis Treatment : Is Surgery Better Than Medical Treatment in Afro-Descendant Populations ?

    Fabienne Louis-sidney1, Serge Arfi1, Moustapha Drame1, Christophe Deligny1, Philippe Cabre1 and Michel de Bandt1, 1University Hospital Martinique, Fort de France, Martinique

    Background/Purpose: Lumbar spinal stenosis (LSS) is a disabling condition, mostly prevalent in the aging population and associated with significant healthcare cost. Clinical presentation involving neurogenic…
  • Abstract Number: 0964 • ACR Convergence 2020

    Is Meniscal Status in the Anterior Cruciate Ligament Injured Knee Associated with Change in Bone Surface Area? An Exploratory Analysis of Data from the KANON Trial

    Barbara Snoeker1, Aleksandra Turkiewicz1, Mike Bowes2, Frank Roemer3, Stefan Lohmander1, Richard Frobell1 and Martin Englund1, 1Lund University, Lund, Sweden, 2Imorphics Ltd, Manchester, United Kingdom, 3Boston University School of Medicine, Boston, MA, and Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany

    Background/Purpose: Bone shape changes, which may be an important feature of osteoarthritis (OA) development, have been observed to occur early in the knee after anterior…
  • Abstract Number: 1115 • ACR Convergence 2020

    The Relation of MRI-Based Cartilage Lesions to Knee Replacement and Knee Pain Severity in Osteoarthritis: The Multicenter Osteoarthritis Study

    Tuhina Neogi1, David Felson1, Kathy Bacon2, James Torner3, Cora Lewis4, Michael Nevitt5 and S. Reza Jafarzadeh1, 1Boston University School of Medicine, Boston, MA, 2Boston University School of Medicine, Boston, 3University of Iowa, Iowa City, IA, 4University of Alabama Birmingham, Birmingham, AL, 5University of California, San Francisco, San Francisco, CA

    Background/Purpose: Recently, the FDA has indicated that data supporting imaging biomarkers of relevance to clinically important outcomes, such as knee replacement (KR) may be considered…
  • Abstract Number: 1470 • ACR Convergence 2020

    Machine Learning-Based Prediction of Knee Replacement in Persons with and Without Radiographic Osteoarthritis Using Clinical and Imaging Features of Osteoarthritis: The Multicenter Osteoarthritis Study

    S. Reza Jafarzadeh1, David Felson1, Michael Nevitt2, James Torner3, Cora Lewis4, Frank Roemer5, Ali Guermazi1 and Tuhina Neogi1, 1Boston University School of Medicine, Boston, MA, 2University of California, San Francisco, San Francisco, CA, 3University of Iowa, Iowa City, IA, 4University of Alabama Birmingham, Birmingham, AL, 5Boston University School of Medicine, Boston, MA, and Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany, Erlangen, Germany

    Background/Purpose: Prior studies of predictors of knee replacement (KR) have often included only a limited set of risk factors, been conducted primarily in knees with…
  • Abstract Number: 1641 • ACR Convergence 2020

    Clinically Important Improvements in Patients with Osteoarthritis Treated with Subcutaneous Tanezumab: Results from a 56-Week Randomized NSAID-Controlled Study

    David Hunter1, Tuhina Neogi2, Melvin Churchill3, Ivan Shirinsky4, Masanari Omata5, Alexander White6, Ali Guermazi2, Robert Fountaine7, Glenn Pixton8, Lars Viktrup9, Mark Brown7, Christine West10 and Kenneth Verburg11, 1Institute of Bone and Joint Research, University of Sydney, St Leonards, New South Wales, Australia, 2Boston University School of Medicine, Boston, MA, 3Arthritis Center of Nebraska, Lincoln, NE, 4Federal State Budgetary Scientific Institution Research Institute of Fundamental and Clinical Immunology, Novosibirsk, Russia, 5Ohimachi Orthopaedic Clinic, Tokyo, Japan, 6Progessive Medical Research, Port Orange, FL, 7Pfizer Inc., Groton, CT, 8Pfizer Inc., Morrisville, NC, 9Eli Lilly and Company, Indianapolis, IN, 10Pfizer Inc, Groton, CT, 11Pfizer Inc, Groton

    Background/Purpose: Subcutaneous (SC) tanezumab, a monoclonal antibody that inhibits nerve growth factor, was investigated for the relief of signs and symptoms of moderate-severe OA in…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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