Abstracts tagged "Osteoarthritis"

Abstract Number: 1922 • ACR Convergence 2022
Multi-Joint Osteoarthritis Phenotypes by Race/Ethnicity and Sex: Preliminary Descriptive Data from the Johnston County Health Study
Sherwin Novin¹, Carolina Alvarez², Todd Schwartz³, Yvonne Golightly⁴ and Amanda Nelson², ¹University of North Carolina, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Chapel Hill, NC, ³University of North Carolina-Chapel Hill, Chapel Hill, NC, ⁴University of Nebraska Medical Center, Omaha, NE
Background/Purpose: To describe phenotypes of multi-joint osteoarthritis (MJOA) definitions by race/ethnicity and sex in a community-based cohort.Methods: The Johnston County Health Study (JoCoHS) is an…
Abstract Number: 0018 • ACR Convergence 2022
Longitudinal Development of Cartilage Microbial DNA Profiles Following Oral Microbiome Inoculation
Emmaline Prinz¹, Leoni Schlupp¹, Vladislav Izda², Emily Nguyen¹, Christopher Dunn³, Cassandra Sturdy¹ and Matlock Jeffries¹, ¹Oklahoma Medical Research Foundation, Oklahoma City, OK, ²Oklahoma Medical Research Foundation, New York, NY, ³University of Oklahoma Health Sciences Center, Edmond, OK
Background/Purpose: Previous studies have associated microbiome changes with human OA and post-traumatic OA mouse models. Our group has previously published a description of cartilage microbial…
Abstract Number: 0398 • ACR Convergence 2022
Comparison of Spondyloarthritis, Rheumatoid Arthritis and Knee Osteoarthritis Occurring in the Setting of HIV Infection
Benjamin Naovarat¹, John Reveille¹, Mark Hwang², Francis Williams³ and Gloria Salazar⁴, ¹University of Texas McGovern Medical School, Houston, TX, ²McGovern Medical School at the University of Texas Health Science Center at Houston, Houston, TX, ³Specialists for Health/Wellmed, Shavano Park, TX, ⁴University of Texas Medical School at Houston/McGovern Medical School, Houston, TX
Background/Purpose: Early in the HIV epidemic, autoimmune diseases such as lupus and rheumatoid arthritis (RA) were uncommonly encountered. With the advent of combined antiretroviral therapy…
Abstract Number: 0849 • ACR Convergence 2022
The Impact of Diabetes Status on Pain and Disability Following Total Joint Arthroplasty for Hip and Knee Osteoarthritis: Variation by Sex and Body Mass Index
J Denise Power¹, Anthony Perruccio², J Roderick Davey², Rajiv Gandhi², Nizar Mahomed², Khalid Syed², Christian Veillette² and Y Raja Rampersaud², ¹Schroeder Arthritis Institute, University Health Network, Toronto, ON, Canada, ²Schroeder Arthritis Institute, University Health Network; University of Toronto, Toronto, ON, Canada
Background/Purpose: Hip and knee total joint arthroplasties (TJA) for osteoarthritis (OA) are frequently performed surgical procedures, representing the majority of direct expenditures for OA. TJA…
Abstract Number: 1641 • ACR Convergence 2022
Determination and Characterization of Patient Subgroups with Different Pain Progression in Hand Osteoarthritis
Coen van der Meulen¹, Lotte van de Stadt¹, Frits Rosendaal¹, Jos Runhaar² and Margreet Kloppenburg¹, ¹Leiden university medical center, Leiden, Netherlands, ²Erasmus Medical Center, Rotterdam, Netherlands
Background/Purpose: Pain is central to hand osteoarthritis (OA). Previous studies reported stable mean pain levels on the short to midterm. Subgroups with different pain trajectories…
Abstract Number: 1891 • ACR Convergence 2022
Osteoarthritis of the Knee, Inflammation, and the Effect of Adalimumab: A Randomized Placebo-Controlled Trial
Walter P Maksymowych¹, Louis Bessette², Robert G Lambert³, Amanda Carapellucci⁴ and Tom Appleton⁵, ¹Department of Medicine, University of Alberta, Edmonton, AB, Canada, ²Centre de l'Ostoporose et de Rhumatologie de Québec, Québec, QC, Canada, ³University of Alberta, Edmonton, AB, Canada, ⁴CARE Arthritis LTD, Edmonton, AB, Canada, ⁵The University of Western Ontario, London, ON, Canada
Background/Purpose: Recent RCTs demonstrated that TNFα inhibition has no effect on pain and MRI-detected synovitis or bone marrow lesions in patients with erosive hand OA.…
Abstract Number: 1907 • ACR Convergence 2022
Strength Training Associates with Less Knee Osteoarthritis: Data from the Osteoarthritis Initiative
Grace Lo¹, Michael Richard², Timothy McAlindon³, Andrea Kriska⁴, Bonny Rockette-Wagner⁴, Charles Eaton⁵, Marc Hochberg⁶, Rebecca Jackson⁷, Kent Kwoh⁸, Michael Nevitt⁹ and Jeffrey Driban¹⁰, ¹Baylor College of Medicine, Houston, TX, ²Tufts Medical Center, Boston, MA, ³Tufts Medical Center, Arlington, MA, ⁴University of Pittsburgh, Pittsburgh, PA, ⁵Brown University, Pawtucket, RI, ⁶University of Maryland School of Medicine, Baltimore, MD, ⁷The Ohio State University, Columbus, OH, ⁸University of Arizona, Tucson, AZ, ⁹University of California San Francisco, Orinda, CA, ¹⁰Tufts Medical Center, Westborough, MA
Background/Purpose: Engagement in strength training has become increasingly popular and is an activity that can involve weight-bearing, heavy lifting, and frequent knee bending; and thus…
Abstract Number: 1923 • ACR Convergence 2022
Co-fluctuations of Knee Pain Between Knees in the Same Person: Data from the Osteoarthritis Initiative (OAI)
Martin Englund¹, Tuhina Neogi² and Aleksandra Turkiewicz¹, ¹Lund University, Lund, Sweden, ²Boston University School of Medicine, Boston, MA
Background/Purpose: Pain in knee osteoarthritis (OA) is often known to fluctuate. However, there is limed knowledge of the pain fluctuations in between knees within the…
Abstract Number: 0019 • ACR Convergence 2022
Bacterial Peptidoglycan in Synovial Tissue at Time of Total Knee Arthroplasty Is Associated with Inflammatory Synovitis and Younger Patient Age
Meaghan Holub¹, Amanda Wahhab², Joseph Rouse², Brandon Jutras³, Klemen Strle⁴, Adam Edelstein⁵ and Robert Lochhead⁶, ¹Central Michigan University College of Medicine, Mount Pleasant, MI, ²Medical College of Wisconsin, Milwaukee, WI, ³Virginia Tech, Blacksburg, VA, ⁴Wadsworth Center, Albany, NY, ⁵Northwestern Medicine, Chicago, IL, ⁶Medical College of Wisconsin, Germantown, WI
Background/Purpose: Peptidoglycan (PG) is a bacterial cell wall component that is known to induce innate immune responses. PG has been identified as a driver of…
Abstract Number: 0504 • ACR Convergence 2022
Three-dimensional Ground Reaction Force Symmetry Metrics Largely Fail to Explain Cartilage Worsening in the Contralateral Knee in Persons with Unilateral Knee Osteoarthritis: The Multicenter Osteoarthritis Study
Patrick Corrigan¹, Cara Lewis², Kerry Costello², Ali Guermazi², Frank Roemer³, Deepak Kumar², David Felson², Kathryn Bacon², Tuhina Neogi⁴, Michael LaValley⁵, Michael Nevitt⁶, Cora E. Lewis⁷, James Torner⁸ and Joshua Stefanik⁹, ¹Saint Louis University, St. Louis, MO, ²Boston University, Boston, MA, ³Friedrich-Alexander University Erlangen Nürnberg, Erlangen, Germany, ⁴Boston University School of Medicine, Boston, MA, ⁵Boston University School of Public Health, Arlington, MA, ⁶University of California San Francisco, Orinda, CA, ⁷University of Alabama at Birmingham, Birmingham, AL, ⁸University of Iowa, Iowa City, IA, ⁹Northeastern University, Boston, MA
Background/Purpose: Knee osteoarthritis (KOA) often starts as a unilateral disease and commonly progresses to bilateral KOA. There is a need to identify mechanisms that explain…
Abstract Number: 0970 • ACR Convergence 2022
Influence of Sociodemographic and Clinical Features on Ground Reaction Force Variability Among Individuals with Symptomatic Knee Osteoarthritis: A Novel Computational Approach
Yvonne Golightly¹, Siqi Xiang², Elyse Borgert², Liubov Arbeeva³, Richard Loeser², Stephen Messier⁴, Amanda Nelson⁵ and J.S. Marron², ¹University of Nebraska Medical Center, Omaha, NE, ²University of North Carolina, Chapel Hill, NC, ³University of North Carolina Chapel Hill, Chapel Hill, NC, ⁴Wake Forest University, Winston-Salem, NC, ⁵University of North Carolina at Chapel Hill, Chapel Hill, NC
Background/Purpose: Abnormally applied forces across the knee during walking play a central role in knee osteoarthritis (OA) disease pathways. Biomechanical data collected continuously during gait…
Abstract Number: 1642 • ACR Convergence 2022
Mast Cells May Explain Sex Differences in Osteoarthritis Pain
Bella Mehta¹, Edward DiCarlo², Fei Wang³, Miguel Otero⁴, Eun Kyung Song⁵, Peter Sculco², Mark Figgie², Susan Goodman², William Robinson⁵ and Dana Orange⁶, ¹Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, ²Hospital for Special Surgery, New York, NY, ³Weil Cornell Medical College, New York, NY, ⁴Hospital for Special Surgery Research Institute, New York, NY, ⁵Stanford University School of Medicine, Palo Alto, CA, ⁶The Rockefeller University, New York, NY
Background/Purpose: Women are at increased risk for knee osteoarthritis(OA) and report more severe pain than men at the time of total knee arthroplasty. It has…
Abstract Number: 1892 • ACR Convergence 2022
Genicular Nerve Block for Pain Management in Patients with Knee Osteoarthritis: A Randomised Double-blind Placebo Controlled Trial
Ernst Shanahan¹, Fin Cai², Frank Voyvodic², Suellen Lyne², Richard Woodman¹, Kokum Dissanayake², Kate Paddick², Giovanna Cheung² and Lucinda Robinson², ¹Flinders University, Adelaide, Australia, ²SALHN, Adelaide, Australia
Background/Purpose: To determine whether Genicular Nerve Block (GNB) is an efficacious treatment for patients with knee osteoarthritis (OA)Methods: Adults with symptomatic knee OA for greater than 3…
Abstract Number: 1908 • ACR Convergence 2022
Should Osteoarthritis Patients with Pain Scores More Than 8/10 Be Analyzed Separately or Excluded from Clinical Trial Protocols, as 72% Screen Positive for Fibromyalgia And/or Depression on a Multidimensional Health Assessment Questionnaire (MDHAQ)?
Juan Schmukler¹, Kathryn Gibson², Tengfei Li³, Joel Block¹ and Theodore Pincus¹, ¹Rush University Medical Center, Chicago, IL, ²Liverpool Hospital, Sydney, Australia, ³Georgetown University, Washington, DC
Background/Purpose: Most osteoarthritis (OA) clinical trial protocols require a 0-10 pain visual numeric scale (VNS) or other quantitative pain score of 4/10 or more for…
Abstract Number: 2208 • ACR Convergence 2022
Diagnostic Performance of Hip Ultrasound in Calcium Pyrophosphate Deposition Disease
Carina Soto-Fajardo¹, Fabian Carranza-Enriquez², Sinthia Solorzano Flores², Abish Angeles², Paola Flores², Raul Pichardo-Bahena², Luis Javier Jara Quezada², Angélica Peña Ayala², Victor-Manuel Ilizaliturri-Sanchez², Georgios Filippou³ and Carlos Pineda², ¹Instituto Nacional de Rehabilitacion "Luis Guillermo Ibarra Ibarra", Ciudad de México, Mexico, ²Instituto Nacional de Rehabilitacion, Ciudad de México, Mexico, ³Rheumatology Department, Luigi Sacco University Hospital, Siena, Italy
Background/Purpose: Calcium Pyrophosphate Deposition Disease (CPPD) is a chronic and potentially incapacitating disease. The reference standard for its diagnosis is the identification of calcium pyrophosphate…

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