Abstracts tagged "osteoarthritis and pain"

Abstract Number: 1249 • 2013 ACR/ARHP Annual Meeting
Contrasting Pathophysiology and Behavioural Responses Associated With Osteoarthritis and An Inflammatory Arthropathy
Sanaa Zaki¹, Margaret M. Smith², Susan Smith¹, Mark Connor³ and Christopher B. Little², ¹Raymond Purves Bone and Joint Research Laboratories, University of Sydney, St Leonards, Australia, ²Raymond Purves Bone and Joint Research Labs, University of Sydney, St Leonards, Australia, ³Australian School of Advanced Medicine, Macquarie University, North Ryde, Australia
Background/Purpose: Osteoarthritis (OA) affects more than 15% of the population, and is the major cause of disability in people over 60. There are no therapies…
Abstract Number: 236 • 2012 ACR/ARHP Annual Meeting
The Relationship Between Vibratory Sense and Somatosensory Pain Measures in Knee Osteoarthritis
Anisha B. Dua¹, Rachel A. Mikolaitis², Tuhina Neogi³, Joel A. Block² and Najia Shakoor⁴, ¹Rheumatology, West Penn Allegheny Health System, Pittsburgh, PA, ²Section of Rheumatology, Rush University Medical Center, Chicago, IL, ³Boston University School of Medicine, Boston, MA, ⁴Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Osteoarthritis is the most common form of arthritis, and is a major cause of pain and disability. Continuous nociceptive input can influence somatosensory…
Abstract Number: 237 • 2012 ACR/ARHP Annual Meeting
Association Between Pain Threshold, Symptoms and Radiographic Knee and Hip Osteoarthritis: The Johnston County Osteoarthritis Project
Adam P. Goode¹, Xiaoyan A. Shi², Jordan Renner³, Richard Gracely⁴, Mehrnaz Maleki-Fischbach⁵ and Joanne M. Jordan⁶, ¹Community and Family Medicine, Duke University, Durham, NC, ²SAS Institute, Inc, Cary, NC, ³UNC School of Medicine, University of North Carolina, Chapel Hill, NC, ⁴Dentistry, University of North Carolina, Chapel Hill, NC, ⁵Medicine, National Jewish Health, Denver, CO, ⁶Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Little is known of the association between pain threshold and knee/hip symptoms as well as radiographic knee/hip osteoarthritis (rOA). These analyses: 1) determined the…
Abstract Number: 238 • 2012 ACR/ARHP Annual Meeting
Inevitable Deterioration? Trajectories and Risk Profiles of Pain in Patients with Radiographic, Symptomatic Knee Osteoarthritis
Jamie E. Collins¹, William M. Reichmann², Jeffrey N. Katz³ and Elena Losina¹, ¹Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ²Orthopedics, Brigham and Womens Hospital, Boston, MA, ³Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Knee pain is the primary reason that patients with OA seek medical care. The goal of this study is to describe pain trajectory over…
Abstract Number: 244 • 2012 ACR/ARHP Annual Meeting
Minimal Clinically Important Difference and Patient Acceptable Symptom State for the Oarsi-Omeract Intermittent and Constant OA Pain (ICOAP) Measure
Z. Anna Liu, Tetyana Kendzerska, Joy Elkayam, Shefali Ram and Gillian A. Hawker, Women's College Research Institute, University of Toronto, Toronto, ON, Canada
Background/Purpose: The Intermittent and Constant Osteoarthritis Pain (ICOAP) measure was developed to evaluate the OA pain experience, independent of the effect of pain on physical…
Abstract Number: 2512 • 2012 ACR/ARHP Annual Meeting
Changes in Bone Marrow Lesion Volume Relate to Changes in Knee Pain. Data From the Osteoarthritis Initiative
Jeffrey B. Driban¹, Lori Lyn Price², Grace H. Lo³, Jincheng Pang⁴, Eric Miller⁴, Charles Eaton⁵, John A. Lynch⁶ and Timothy E. McAlindon⁷, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ³Michael E. DeBakey Veterans Affairs Medical Center, Houston, TX, ⁴Department of Electrical and Computer Engineering, Tufts University, Medford, MA, ⁵Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Providence, RI, ⁶Department of Epidemiology and Biostatistics, University of California at San Francisco, San Francisco, CA, ⁷Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Changes in bone marrow lesions (BMLs), common magnetic resonance (MR) imaging findings in osteoarthritis (OA), are predictive of OA progression. However, it is unclear…
Abstract Number: 34 • 2012 ACR/ARHP Annual Meeting
Rebamipide Attenuates Pain Severity and Cartilage Degeneration in a Rat Model of Osteoarthritis by Downregulating Oxidative Damage and Catabolic Activity in Chondrocytes
Su-Jin Moon¹, Mi-La Cho², Yeon-Sik Hong³, Sung-Hwan Park⁴ and Jun-Ki Min¹, ¹Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul, South Korea, ²Rheumatism Research Center, Catholic Research Institute of Medical Science, Catholic University of Korea, Seoul, South Korea, ³Our Lady of Mercy Hospital, Inchon, South Africa, ⁴Catholic University of Korea, Seoul, South Korea
Background/Purpose: The development and progression of osteoarthritis (OA) are now believed to involve inflammation, even in the early stage of disease. Proinflammatory cytokines and chemokines are…
Abstract Number: 1581 • 2012 ACR/ARHP Annual Meeting
The Association Between Symptoms, Pain Coping Strategies, and Physical Activity Among People with Symptomatic Knee and Hip Osteoarthritis
Susan L. Murphy¹, Anna Kratz², David A. Williams³ and Michael E. Geisser², ¹Physical Medicine & Rehabilitation, University of Michigan, Ann Arbor, MI, ²Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, ³Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI
Background/Purpose: Effective use of coping strategies by people with chronic pain conditions is associated with better functioning and adjustment to chronic disease. Although the effects…
Abstract Number: L1 • 2012 ACR/ARHP Annual Meeting
A Randomized, Placebo-Controlled Phase 2 Study of ARRY-797 in Patients with Osteoarthritis Pain Refractory to NSAID Treatment Showed Statistically Significant Improvements in WOMAC Pain and in Biomarkers of Bone and Cartilage Degradation
Alan J. Kivitz¹, Shane G. Christensen², John Agaiby³, Egilius Spierings⁴, Julie Daves⁵, Roger Aitchison⁶, Stephen G. Miller⁷, Karsten Witt⁸ and Joseph Gimbel⁹, ¹Altoona Center for Clinical Research, Duncansville, PA, ²J. Lewis Research, Inc., Salt Lake City, UT, ³Clinical Investigation Specialists, Gurnee, IL, ⁴MedVadis Research Corporation, Watertown, MA, ⁵Clinical Operations, Array Biopharma, Inc., Boulder, CO, ⁶Biostatistics & Data Management, Array Biopharma, Inc., Boulder, CO, ⁷Translational Medicine, Array Biopharma, Inc., Boulder, CO, ⁸Clinical Sciences, Array Biopharma, Inc., Boulder, CO, ⁹Arizona Research Center, Phoenix, AZ
Background/Purpose: Osteoarthritis (OA) is the most common chronic joint disease and OA pain is a leading cause of work disability. p38 inhibition suppresses the production…
Abstract Number: 1556 • 2012 ACR/ARHP Annual Meeting
The Effect of Ginger Therapy On Symptoms of Osteoarthritis: An Open Pilot Study
Tessa Therkleson, Nursing, Edith Cowan University, Perth, Australia
Background/Purpose: Osteoarthritis (OA) is a painful, progressive disease of synovial joints characterised by deterioration of cartilage and bone and inflammation. Osteoarthritis of the knee and…
Abstract Number: 2631 • 2012 ACR/ARHP Annual Meeting
Radiographic Osteoarthritis Severity Is Associated with an Increased Risk of Developing Knee Pain: Findings From the Osteoarthritis Initiative
Jingbo Niu¹, David T. Felson², Tuhina Neogi³ and Yuqing Zhang⁴, ¹Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Clinical Epidemiology, Boston Univ School of Medicine, Boston, MA, ⁴School of Medicine, Boston Univ School of Medicine, Boston, MA
Background/Purpose : While knee pain is a major complaint from subjects with knee osteoarthritis (OA), most epidemiologic studies have found only weak to moderate associations…
Abstract Number: 1126 • 2012 ACR/ARHP Annual Meeting
Comparison between Osteoartritis Initiative and CHECK study (Cohort Hip & Cohort Knee); Development of pain and function during 4 years follow-up
Janet Wesseling¹, Sita M.A. Bierma-Zeinstra², Margreet Kloppenburg³, Johannes WJ Bijlsma⁴ and CHECK steering group⁵, ¹Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, Netherlands, ²Orthopaedics and General Practice, Erasmus MC - University Medical Center, Rotterdam, Netherlands, ³Department Rheumatology and Department of Clinical Epidemiology, Leiden University Medical Centre, Leiden, The Netherlands, Leiden, Netherlands, ⁴Dept of Rheumatology & Immun, University Medical Center Utrecht, Utrecht, Netherlands, ⁵Dept of Rheumatology & Immun, University Medical Center Utrecht, Utrecht
Background/Purpose: Pain and disability related to osteoarthritis (OA) may generally be considered to be chronic, but it is known that its course can be very…
Abstract Number: 1128 • 2012 ACR/ARHP Annual Meeting
Different of Patterns Knee Pain Trajectories: Longitudinal Data From the Osteoarthritis Initiative (OAI)
Joseph Devich Jr.¹, Michael J. Hannon², Zhijie Wang², Robert M. Boudreau³ and C. Kent Kwoh⁴, ¹Imrp, UPMC Shadyside, Pittsburgh, PA, ²Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, ³Epidemiology, University of Pittsburgh, Pittsburgh, PA, ⁴School of Medicine, Department of Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Knee osteoarthritis (KOA) is one of the most common forms of arthritis and the most common cause of disability among the elderly. Knee pain…
Abstract Number: 1135 • 2012 ACR/ARHP Annual Meeting
Combined Glucosamine and Chondroitin Sulfate, Once of Three Times Daily, Provide Clinically Relevant Analgesia in Knee Osteoarthritis
Jose R. Provenza¹, Samuel K. Shinjo², Joyce M. Silva³, Carla RGS. Peron⁴ and Francisco AC Rocha⁵, ¹Rheumatology, Pontifícia Universidade Católica de Campinas, Campinas, Brazil, ²Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ³Clinical Research, Sao Paulo, Brazil, ⁴Clinical Research, Laboratórios Aché Ltda, Sao Paulo, Brazil, ⁵Rheumatology, Brazilian Registry of Spondyloarthritis, São Paulo, Brazil
Background/Purpose: The analgesic efficacy of combined glucosamine and chondroitin sulfate (CS) in knee osteoarthritis (OA) remains controversial. Criticism to previous studies includes small sample size,…
Abstract Number: 1115 • 2012 ACR/ARHP Annual Meeting
Relation Between Hip Dysplasia, Pain, and Osteoarthritis in a Cohort of Patients with Hip Symptoms
Johanne Morvan¹, Ronan Bouttier², Bernard Mazieres³, Evelyne Verrouil³, Jacques Pouchot⁴, Anne-Christine Rat⁵, Joel Coste⁶ and Alain Saraux⁷, ¹Rheumatology, CH Quimper, Quimper, France, ²Radiology, CHU Brest, Brest, ³Rhumatologie, Hopital de Rangueil, Toulouse, FRANCE, France, ⁴Medecine Interne, Hopital Louis Mourier, Colombes, FRANCE, France, ⁵Rheumatology, Nancy Teaching Hospital, Nancy, France, ⁶Université de Lorraine, Paris Descartes University, APEMAC, EA 4360, F- 54 000, France, Nancy, France, ⁷Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France
Background/Purpose: The relationship between acetabular dysplasia (HD) and hip osteoarthritis remains unclear, especially for mild forms of dysplasia. Our objectives were to estimate the prevalence…

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