Abstracts tagged "OA"

Abstract Number: 1405 • 2016 ACR/ARHP Annual Meeting
Quality Measures in High Priority Rheumatologic Diseases: A Systematic Literature Review and Analysis
Melissa Wells¹, Stephanie Giattino¹, Malithi Jayasundara¹, Lisa Criscione-Schrieber¹, Arif Kamal² and Eugene William St.Clair¹, ¹Rheumatology, Duke University Medical Center, Durham, NC, ²Oncology, Duke University Medical Center, Durham, NC
Background/Purpose: To identify published quality measures in rheumatoid arthritis (RA), osteoarthritis (OA), osteoporosis, spondyloarthropathy (SpA) and gout for the purpose of summarizing the existing measures…
Abstract Number: 2029 • 2016 ACR/ARHP Annual Meeting
Risk of Knee Pain, Radiographic Osteoarthritis and Knee Arthroplasty in Retired Professional Footballers Compared to the General Population
Gwen Fernandes^1,2,3, Sanjay M Parekh^1,2, Jonathan P Moses^1,2, Colin Fuller⁴, Brigitte Scammell^1,2,3, Mark Batt^1,2,3, Weiya Zhang^1,2,3 and Michael Doherty^1,2,3, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ²Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ³Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ⁴Colin Fuller Consultancy Ltd, Nottingham, United Kingdom
Background/Purpose: To determine the prevalence of knee pain (KP), radiographic knee osteoarthritis (RKOA) and total knee replacements (TKR) in ex-professional footballers compared to general population…
Abstract Number: 2128 • 2016 ACR/ARHP Annual Meeting
Autophagic Clearance of Dysfunctional Mitochondria Requires Parkin in Human Chondrocytes
Mohammad Y Ansari¹ and Tariq M. Haqqi², ¹Anatomy & Neurobiology, Northeast Ohio Medical University, Roostown, OH, ²Anatomy & Neurobiology, Northeast Ohio Medical University, Rootstown, OH
Background/Purpose:
Abstract Number: 1136 • 2015 ACR/ARHP Annual Meeting
IL-1β-Induced Stress Granules Sequester COX-2 mRNA and Regulates Its Expression in Human OA Chondrocytes
Mohammad Ansari¹ and Tariq Haqqi², ¹Anatomy & Neurobiology, Northeast Ohio Medical University, Roostown, OH, ²Anatomy & Neurobiology, Northeast Ohio Medical University, Rootstown, OH
Background/Purpose: Stress granules (SGs) are ribonucleoprotein complexes assembled in the cytoplasm of eukaryotic cells to respond adequately to stress (e.g. heat shock, UV irradiation, oxidative…
Abstract Number: 1266 • 2015 ACR/ARHP Annual Meeting
Rheumatologic Diagnoses, Characteristics and Needs of Somali Patients Referred to a Rheumatology Clinic Serving the Somali Population
Elizabeth Miller¹, Elie Gertner², Rosemary Quirk¹ and Maribet McCarty¹, ¹Hennepin County Medical Center, Minneapolis, MN, ²Section of Rheumatology, Regions Hospital and University of Minnesota, St. Paul, MN
Background/Purpose: With the growing immigrant and refugee population in the United States, the landscape of medicine is constantly changing. In order to provide quality healthcare,…
Abstract Number: 2169 • 2015 ACR/ARHP Annual Meeting
Low Education Is Associated with Mortality Among Individuals with Knee and/or Hip OA: The Johnston County Osteoarthritis Project
Rebecca J. Cleveland¹, Todd A. Schwartz², Jordan B. Renner³, Joanne M. Jordan⁴ and Leigh F. Callahan⁴, ¹University of North Carolina at Chapel Hill, Chapel Hill, NC, ²School of Nursing, University of North Carolina, Chapel Hill, NC, ³Radiology, University of North Carolina, Chapel Hill, NC, ⁴Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Low socioeconomic status (SES) is associated with an increased risk of death as well as knee and/or hip osteoarthritis (OA). SES and mortality has…
Abstract Number: 2172 • 2015 ACR/ARHP Annual Meeting
Distribution of Clinical Osteoarthritis and Associations to Health-Related Quality of Life in a Population-Based Osteoarthritis Cohort
Guro Økelsrud Lombnæs¹, Karin Magnusson² and Kåre Birger Hagen¹, ¹National Advisory Unit on Rehabilitation in Rheumatology, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, National Advisory Unit on Rehabilitation in Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Osteoarthritis (OA) is a major cause of musculoskeletal pain and disability, and is commonly reported to impair health-related quality of life (HRQoL). We aimed…
Abstract Number: 2405 • 2015 ACR/ARHP Annual Meeting
Knee Sounds May Predict Osteoarthritis Severity, Symptoms and Function: Pilot Investigation Toward a Novel Dynamic Imaging System
Victoria Manning¹, Costas Yiallourides², Mads Brevadt¹, Alastair Moore², Edouard Auvinet¹, Patrick Naylor² and Justin Cobb¹, ¹Musculoskeletal Lab, Imperial College London, London, United Kingdom, ²Communications and Signal Processing Group, Imperial College London, London, United Kingdom
Background/Purpose: Knee sounds (KS) may provide a low-cost, risk-free means of identifying presence and severity of knee osteoarthritis (KOA). Unlike static imaging, KS during dynamic…
Abstract Number: 2408 • 2015 ACR/ARHP Annual Meeting
The Quality of Community-Based Osteoarthritis Care Can be Improved. Results from a Systematic Review and Meta-Analysis
Kåre Birger Hagen¹, Geir Smedslund², Nina Østerås² and Gro Jamtvedt³, ¹National Advisory Unit on Rehabilitation in Rheumatology, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²National Advisory Unit on Rehabilitation in Rheumatology, Department of Rheumatology,, Diakonhjemmet Hospital, Oslo, Norway, ³The Norwegian Knowledge Center for the Health Services, Oslo, Norway
Background/Purpose: The burden of osteoarthritis (OA) is substantial and expected to increase because people are getting older and heavier. Health care providers need to monitor…
Abstract Number: 3249 • 2015 ACR/ARHP Annual Meeting
Pooled Efficacy and Safety from Phase 3 Controlled Studies of Tanezumab in Patients with Osteoarthritis
Leslie Tive¹, David Radin², Alfonso Bello³, Ha Nguyen¹, Mark T. Brown⁴, Christine R. West⁴ and Kenneth M. Verburg⁴, ¹Pfizer, Inc, New York, NY, ²Stamford Therapeutics Consortium, Stamford, CT, ³Illinois Bone & Joint Inst, Glenview, IL, ⁴Pfizer Inc., Groton, CT
Background/Purpose: Tanezumab (TNZ) significantly reduces pain and improves physical function and Patient's Global Assessment (PGA) in patients with chronic pain. From June 2010 to August…
Abstract Number: 321 • 2015 ACR/ARHP Annual Meeting
Effects of Bariatric Surgery on Long-Term Quality of Life Outcomes for Obese Patients with Osteoarthritis
Ankita Satpute¹, Deepak L. Bhatt², Sangeeta Kashyap³, Philip Schauer⁴, Colin O'Rourke⁵, James Bena⁵ and M. Elaine Husni⁶, ¹Case Western Reserve University School of Medicine, Cleveland, OH, ²Brigham and Women’s Hospital Heart & Vascular Center, Boston, MA, ³Endocrinology, Diabetes and Metabolism, Cleveland Clinic Foundation, Cleveland, OH, ⁴General Surgery, Cleveland Clinic Foundation, Cleveland, OH, ⁵Department of Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, ⁶Rheumatology Dept A50, Cleveland Clinic Foundation, Cleveland, OH
Background/Purpose: Osteoarthritis (OA) remains a debilitating burden for patients and a challenge to their physicians, as there is no known cure. Obesity has been linked…
Abstract Number: 334 • 2015 ACR/ARHP Annual Meeting
Lifetime Risk of Symptomatic Hand Osteoarthritis: The Johnston County Osteoarthritis Project
Jin Qin¹, Kamil E. Barbour¹, Louise Murphy¹, Charles G. Helmick¹, Nancy A. Baker², Kristina Theis¹, Todd Schwartz^3,4, Jordan B. Renner⁵, Amanda Nelson⁶, Kelli Allen⁷ and Joanne M. Jordan⁸, ¹Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ²University of Pittsburgh, Pittsburgh, PA, ³Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁵UNC School of Medicine, University of North Carolina, Chapel Hill, NC, ⁶Division of Rheumatology, Allergy, and Immunology and Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC, ⁷University of North Carolina, Chapel Hill, NC, ⁸Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Osteoarthritis (OA) affects 27 million adults in the United States. Symptomatic hand osteoarthritis (SHOA) is a common condition that affects hand strength and function.…
Abstract Number: 339 • 2015 ACR/ARHP Annual Meeting
More Inflammatory Signs on Ultrasound, Severe Pain and Stiffness Are Associated with Erosive Than Non-Erosive Hand Osteoarthritis
Olga Sleglova¹, Olga Ruzickova², Karel Pavelka¹ and Ladislav Senolt², ¹Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, ²Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, Prague, Czech Republic
Background/Purpose: Hand osteoarthritis (HOA) causes considerable pain and disability. Radiographic HOA features show only a modest association with symptoms in HOA. Ultrasound is an easy…
Abstract Number: 2236 • 2014 ACR/ARHP Annual Meeting
Plant–Derived Products Are Effective for Treatment of OA Pain and Safer Than Other Active Therapies
Laura Laslett, Xingzhong Jin and Graeme Jones, Menzies Research Institute Tasmania, University of Tasmania, HOBART, Australia
Background/Purpose: Osteoarthritis (OA) is a leading cause of chronic disability. There are no approved treatments for modifying the disease course, therefore disease management consists of…
Abstract Number: 1885 • 2014 ACR/ARHP Annual Meeting
Integrative Omics Profiling Reveals Dysregulated Novel Pathways Mediated By microRNAs and DNA Methylation in Osteoarthritis
Kathleen M. Fisch¹, Ryuichiro Akagi², Oscar Alvarez-Garcia¹, Takeshi Teramura¹, Yuta Muramatsu¹, Masahiko Saito³, Stuart Duffy¹, Shawn Grogan⁴, Takahisa Sasho⁵, Darryl D'Lima⁶, Andrew I. Su¹ and Martin K. Lotz¹, ¹Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, ²The Scripps Research Institute, San Diego, CA, ³Orthopaedic Surgery, Toho University Sakura Medical Center, Sakura, Japan, ⁴The Scripps Research Institute, La Jolla, CA, ⁵Orthopaedic Surgery, Chiba University School of Medicine, Chiba, Japan, ⁶SCORE, The Scripps Research Institute, La Jolla, CA
Background/Purpose: Osteoarthritis (OA) is a prevalent joint disease, with several identified clinical risk factors. However, the search for genetic risk factors by candidate gene and…

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