Abstracts tagged "OA"

Abstract Number: 2945 • 2017 ACR/ARHP Annual Meeting
Incident Hand OA Is Strongly Associated with Reduced Peripheral Blood Leukocyte Telomere Length
Timothy E. McAlindon¹, Mary Roberts², Lena Franziska Schaefer³, Jeffrey B. Driban⁴, Jeffrey Duryea³, Francisco J Blanco⁵, Jose-Luis Fernandez-Garcia⁶ and Charles Eaton⁷, ¹Division of Rheumatology, Tufts Medical Center, Boston, MA, ²Center for Primary Care and Prevention, Memorial Hospital of Rhode Island, Pawtucket, RI, ³Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ⁴Rheumatology, Tufts Medical Center, Boston, MA, ⁵Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruña, Spain, ⁶Genetic Department, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain, ⁷Family Medicine and Epidemiology, Warren Alpert Medical School, School of Public Health, Brown University, Providence, RI
Background/Purpose: Hand OA (HOA) is a painful, destructive and deforming polyarticular disorder that impairs an individual’s ability to perform manipulative activities of daily life and…
Abstract Number: 58 • 2017 ACR/ARHP Annual Meeting
Cartilage-like Tissue Generation By 3D-Bioprinting of Induced Pluripotent Stem Cells
Rocío Castro-Viñuelas¹, Alma Forsman², Erdem Karabulut³, Erik Romberg³, Camilla Brantsing², Mats Brittberg⁴, Anders Lindahl², Paul Gatenholm³ and Stina Simonsson², ¹Cell Therapy and Regenerative Medicine research group. Rheumatology Division. Institute of Biomedical Research of A Coruña (INIBIC). Dep. of Biomedical Sciences, Medicine and Physiotherapy, University of A Coruña, A Coruña, Spain, ²Institute of Biomedicine at Sahlgrenska Academy, Department of Clinical Chemistry and Transfusion Medicine, University of Gothenburg., Gothenburg, Sweden, ³3D Bioprinting Center, Dept. of Chemistry and Chemical Engineering, Chalmers University of Technology, Gothenburg, Sweden, ⁴Cartilage Repair Unit, University of Gothenburg, Region Halland Orthopaedics, Kungsbacka Hospital, Kungsbacka, Sweden
Background/Purpose: Cartilage lesions due to traumatic or pathological conditions slowly grow over the time and may lead to osteoarthritis (OA). As a prospective treatment for…
Abstract Number: 347 • 2017 ACR/ARHP Annual Meeting
Disease Burden at One Academic Rheumatology Routine Care Setting Is Similar in Osteoarthritis (OA) and Rheumatoid Arthritis (RA) at First Visit but Significantly Greater in OA at a 6-Month Follow-up Visit
Jacquelin R. Chua¹, Shakeel M. Jamal¹, Isabel Castrejón¹, Najia Shakoor¹, Anne-Marie Malfait², Joel A. Block² and Theodore Pincus², ¹Division of Rheumatology, Rush University Medical Center, Chicago, IL, ²Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Osteoarthritis commonly is regarded as less severe and less debilitating than RA. However, limited data are available for direct comparison of OA versus RA,…
Abstract Number: 1059 • 2017 ACR/ARHP Annual Meeting
Cost-Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis
John B. Wong¹, Mei Chung², Lori Lyn Price³ and Chenchen Wang^4,5, ¹Tufts Medical Center, Boston, MA, ²Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, ³Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁴Rheumatology, Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA, ⁵Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: A single-blind randomized comparative effectiveness trial showed that Tai Chi yielded beneficial effects similar to those of a standard course of physical therapy in…
Abstract Number: 1185 • 2017 ACR/ARHP Annual Meeting
Acupotomy Therapy for Joint Pain Relief of Knee Osteoarthritis-Systematic Review and Meta-Analysis
Jia Li¹, Puwei Yuan², Rongqiang Zhang¹, Bin Chen³, Bo Dong¹, Wulin Kang¹, Xiaoliang Zhang³, Stephanie Hyon⁴, Raveendhara R. Bannuru⁵, William F. Harvey⁴ and Chenchen Wang⁴, ¹Shaanxi University of Chinese Medicine, Xianyang, China, ²Traditional Chinese Medicine College, Shaanxi University of Chinese Medicine, Xianyang, China, ³Integrative TCM and Western Medicine College, Shaanxi University of Chinese Medicine, Xianyang, China, ⁴Rheumatology, Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA, ⁵Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA
Background/Purpose: Knee osteoarthritis (KOA) is a major public health problem and a leading cause of long-term pain and disability. Few effective medical treatments for the…
Abstract Number: 307 • 2016 ACR/ARHP Annual Meeting
Visualizing Different Patterns of Cartilage Change: A Two-Year Study of Data from the Osteoarthritis Initiative
Amanda R. Canavatchel¹, Grace H. Lo², Michael P. LaValley³, Ming Zhang¹, Jeffrey B. Driban⁴, Lori Lyn Price⁵, Eric Miller⁶, Charles Eaton⁷ and Timothy E. McAlindon⁸, ¹Tufts Medical Center, Boston, MA, ²Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX, ³Biostatistics, Boston University School of Public Health, Boston, MA, ⁴Rheumatology, Tufts Medical Center, Boston, MA, ⁵Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁶Department of Electrical and Computer Engineering, Tufts University, Medford, MA, ⁷Brown University, Providence, RI, ⁸Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Traditionally, regions of the knee that are assessed in clinical trials are selected based on anatomy or responsiveness to change. However, it is unclear…
Abstract Number: 314 • 2016 ACR/ARHP Annual Meeting
The Clinical Efficacy and Safety of the Gumiganhwal-Tang in Knee Osteoarthritis: A Phase II Randomized Double Blind Placebo Controlled Study
Sung Hae Chang¹, Mi-Il Kang² and Seong-Su Nah³, ¹Internal Medicine, Rheumatology, Soonchunhyang University, College of Medicine, Cheonan, South Korea, ²Dankuk University Hospital, Cheonan, Korea, The Republic of, ³Soonchunhyang University, College of Medicine, Cheonan, South Korea
Background/Purpose: Gumiganghwal-tang (GMGHT) is a traditional herbal medicine consisted of nine different herbs. GMGHT inhibit the production and mRNA expression of inflammatory cytokine production TNF…
Abstract Number: 683 • 2016 ACR/ARHP Annual Meeting
Risk Factors of Uveitis in Ankylosing Spondylitis
Feng Wang¹, Qin Xue², Li Sun³ and Niansong Wang⁴, ¹Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China, ²Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China, ³Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing, China, ⁴Shanghai Jiao Tong University Affiliated Sixth People's Hospital, shanghai, China
Background/Purpose: Uveitis is the most common extra-articular manifestation in patients with ankylosing spondylitis (AS).The prevalence and characteristics of uveitis in AS have been studied in previous literatures while…
Abstract Number: 1018 • 2016 ACR/ARHP Annual Meeting
Dietary Intake of Fiber and Risk of Knee Osteoarthritis
Zhaoli (Joy) Dai¹, Jingbo Niu¹, Yuqing Zhang², Paul Jacques³ and David T. Felson⁴, ¹Clinical epidemiology research and training unit, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology and Training Unit, Boston University School of Medicine, Boston, MA, ³Jean Mayer USDA Human Nutrition Research Center on Aging and Friedman School of Nutrition Science and Policy, Tufts University, Boston, Boston, MA, ⁴Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Background/Purpose: Dietary fiber reduced risks of metabolic diseases in part by reducing systemic inflammation and body weight. These factors are both likely to contribute to…
Abstract Number: 1124 • 2016 ACR/ARHP Annual Meeting
IL37 Rescues Human OA Cartilage Explants from GAG Release
Ellen van Geffen¹, Arjan van Caam², Henk van Beuningen², Elly Vitters², Esmeralda Blaney Davidson² and Peter M. van der Kraan², ¹Experimential Rheumatology, Radboud university medical center, Nijmegen, Netherlands, ²Experimental Rheumatology, Radboud university medical center, Nijmegen, Netherlands
Background/Purpose: In healthy cartilage, there is a balance between anabolic and catabolic activities of chondrocytes that maintains the functional integrity of the extracellular matrix. However,…
Abstract Number: 1405 • 2016 ACR/ARHP Annual Meeting
Quality Measures in High Priority Rheumatologic Diseases: A Systematic Literature Review and Analysis
Melissa Wells¹, Stephanie Giattino¹, Malithi Jayasundara¹, Lisa Criscione-Schrieber¹, Arif Kamal² and Eugene William St.Clair¹, ¹Rheumatology, Duke University Medical Center, Durham, NC, ²Oncology, Duke University Medical Center, Durham, NC
Background/Purpose: To identify published quality measures in rheumatoid arthritis (RA), osteoarthritis (OA), osteoporosis, spondyloarthropathy (SpA) and gout for the purpose of summarizing the existing measures…
Abstract Number: 2029 • 2016 ACR/ARHP Annual Meeting
Risk of Knee Pain, Radiographic Osteoarthritis and Knee Arthroplasty in Retired Professional Footballers Compared to the General Population
Gwen Fernandes^1,2,3, Sanjay M Parekh^1,2, Jonathan P Moses^1,2, Colin Fuller⁴, Brigitte Scammell^1,2,3, Mark Batt^1,2,3, Weiya Zhang^1,2,3 and Michael Doherty^1,2,3, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ²Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ³Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ⁴Colin Fuller Consultancy Ltd, Nottingham, United Kingdom
Background/Purpose: To determine the prevalence of knee pain (KP), radiographic knee osteoarthritis (RKOA) and total knee replacements (TKR) in ex-professional footballers compared to general population…
Abstract Number: 2128 • 2016 ACR/ARHP Annual Meeting
Autophagic Clearance of Dysfunctional Mitochondria Requires Parkin in Human Chondrocytes
Mohammad Y Ansari¹ and Tariq M. Haqqi², ¹Anatomy & Neurobiology, Northeast Ohio Medical University, Roostown, OH, ²Anatomy & Neurobiology, Northeast Ohio Medical University, Rootstown, OH
Background/Purpose:
Abstract Number: 2348 • 2016 ACR/ARHP Annual Meeting
Does Arthritis in Other Joints and Spine Influence the 1-Year Outcome of Total Hip Replacement? a Prospective European Multicenter Cohort Study Measuring the Influence of Musculoskeletal Morbidity
Joerg Huber¹, Paul Dieppe², Karsten Dreinhoefer³, Klaus-Peter Günther⁴, Georg Ruflin⁵ and Andrew Judge⁶, ¹Orthopedics, Triemli Spital, Zurich, Switzerland, ²Exeter Medical School, University of Exeter, Exeter, United Kingdom, ³Centre of Musculosceletal Surgery, Charité, Charite, Berlin, Berlin, Germany, ⁴University Center of Orthopedics and Traumatology, Technische Universität, Dresden, Germany, ⁵Orthopedics, Kantonsspital Aarau, Aarau, Switzerland, ⁶Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom
Background/Purpose: Whilst arthritis in other affected joints and back pain is known to lead to worse outcomes following total hip replacement surgery, these risk factors…
Abstract Number: 2354 • 2016 ACR/ARHP Annual Meeting
Pharmaceutical Grade Chondroitin Sulfate Improves Knee Osteoarthritis Symptoms More Than Placebo and As Much As Celecoxib: Results of the Chondroitin Vs Celecoxib Vs Placebo Trial (CONCEPT)
J-Y Reginster and CONCEPT Authors' Group, Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, Belgium
Background/Purpose: For the assessment of Symptomatic Slow Acting Drugs in Osteoarthritis (SYSADOAs), regulatory Agencies request the assessment of two co-primary endpoints: pain and function. They…

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