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Abstracts tagged "Myositis"

  • Abstract Number: 1081 • ACR Convergence 2020

    Patient-reported Outcomes in Early Autoimmune Inflammatory Myopathies

    Valérie Leclair1, Brett Thombs2, Mianbo Wang3, Evelyne Vinet4, Alexandra Albert5 and Marie Hudson6, 1Division of Rheumatology, Jewish General Hospital, Montreal, QC, Canada, 2Department of Psychology, McGill University, Montreal, QC, Canada, 3Lady Davis institute for Medical Research, Montreal, QC, Canada, 4McGill University Health Center, Montreal, QC, Canada, 5Division of Rheumatology, Centre Hospitalier de l’Université Laval, Québec, QC, Canada; Department of Medicine, Université Laval, Québec, QC, Canada., Neuville, Canada, 6Division of Rheumatology, Jewish General Hospital, Montréal, QC, Canada

    Background/Purpose: Patient-reported outcomes (PROs) are increasingly used in rheumatology. Such outcomes are under-reported in autoimmune inflammatory myopathies (AIM) especially in incident cohorts. The objective of…
  • Abstract Number: 1559 • ACR Convergence 2020

    Fully Automatic Assessment of Nail Fold Capillaroscopy Software – Early Results

    Olga Brzezińska1, Krzysztof Rychlicki-Kicior2 and Joanna Makowska1, 1Department of Rheumatology, Medical University of Lodz, Poland, Lodz, Lodzkie, Poland, 2University of Economics and Human Sciences in Warsaw, Poland, Lodz, Poland

    Background/Purpose: Changes in capillaroscopy nailfold image are a valuable element in the diagnostic procedure and monitoring of systemic sclerosis as well as other systemic diseases.…
  • Abstract Number: 1061 • ACR Convergence 2020

    Daily Myositis Symptom Changes Collected via a Smartphone-Based App Are Associated with Flare Occurrence – Providing Evidence of Potential Digital Biomarkers

    Alexander Oldroyd1, Belay Yimer2, Max Little3, William Dixon2 and Hector Chinoy4, 1University of Manchester, Manchester, United Kingdom, 2Centre for Epidemiology Versus Arthritis, University of Manchester, Manchester, United Kingdom, 3University of Birmingham, Birmingham, United Kingdom, 4The University of Manchester, Manchester, United Kingdom

    Background/Purpose: The concept of idiopathic inflammatory myopathy (IIM) flare is widely used, although no consensus definition exists. Studies have demonstrated the feasibility and utility of…
  • Abstract Number: 1082 • ACR Convergence 2020

    The Presence of Anti-Jo1, anti-PL7, And/or anti-MDA5 Antibodies in Idiopathic Inflammatory Myopathy Confers an Increased Risk of a Significant Restrictive Pulmonary Defect

    Dmitriy Cherny1 and Carrie Richardson1, 1Rush University Medical Center, Chicago, IL

    Background/Purpose: A subset of patients with idiopathic inflammatory myopathy develop significant restrictive lung disease, although risk factors for this are poorly defined. Autoantibodies may be…
  • Abstract Number: 1574 • ACR Convergence 2020

    Over Half of Patients with Immune Checkpoint Inhibitor-related Myositis, Myasthenia Gravis and/or Myocarditis Have Autoantibodies: Results from a Systematic Literature Review

    Nilasha Ghosh1, Karmela Kim Chan2, Bridget Jivanelli3 and Anne Bass1, 1Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 2Hospital For Special Surgery, New York, NY, 3Hospital for Special Surgery, New York

    Background/Purpose: Although immune checkpoint inhibitor (ICI) cancer treatments are known to activate cytotoxic T-cells, autoantibodies may also contribute to the development of immune-related adverse events…
  • Abstract Number: 082 • 2020 Pediatric Rheumatology Symposium

    Anti-Mitochondrial Autoantibodies Are Associated with Dysphagia in Juvenile and Adult Myositis, and with Persistent Weakness and Cardiomyopathy in Adult Myositis

    Sara Sabbagh1, Iago Pinal-Fernandez 2, Maria Casal-Dominguez 3, Frederick W. Miller 4, Lisa G. Rider 5, Andrew Mammen 3 and Lisa Christopher-Stine 6, 1NIH/NIAMS, Bethesda, 2National Institutes of Health, Bethesda, 3NIH, Bethesda, 4Bethesda, 5NIEHS, NIH, Garrett Park, 6Johns Hopkins University, Baltimore

    Background/Purpose: We analyzed the prevalence of anti-mitochondrial autoantibodies (AMA) in both juvenile-(JM) and adult-onset myositis cohorts and investigated phenotype differences between juvenile and adult myositis…
  • Abstract Number: 1294 • 2019 ACR/ARP Annual Meeting

    Alterations in Activin A-Myostatin-Follistatin System Associate with Disease Activity in Inflammatory Myopathies

    Lucia Vernerová1, Veronika Horvathová 2, Tereza Kropáčková 3, Martina Vokurková 2, Martin Klein 1, Sabina Oreska 4, Katerina Kubinova 5, Herman Mann 4, Maja Spiritovic 6, Hana Storkanova 1, Olga Kryštůfková 1, Michal Tomcik 4, Jozef Ukropec 7, Barbara Ukropcová 7 and Jiří Vencovský 4, 1Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague, Czech Republic, 2Institute of Rheumatology, Prague, Czech Republic, 3Institute of Rheumatology, Prague, 4Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, 5Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, 6Faculty of Physical Education and Sport, Department of Physiotherapy, Charles University, Prague, Czech Republic, Prague 2, Hlavni mesto Praha, Czech Republic, 7Institute of Experimental Endocrinology, Biomedical center, Slovak Academy of Sciences, Bratislava, Slovakia

    Background/Purpose: The aim of this study was to investigate myokines involved in muscle atrophy such as myostatin, follistatin and activin A, in idiopathic inflammatory myopathies…
  • Abstract Number: 2245 • 2019 ACR/ARP Annual Meeting

    Polymyositis (PM) and Dermatomyositis (DM) Symptom Flares and Associated Impact from the Patient Perspective

    Lisa Christopher-Stine1, William Kelly 2, George Wan 3, Linda Kobert 4 and Michael Reed 5, 1Johns Hopkins University School of Medicine, Baltimore, MD, 2Johns Hopkins Myositis Center, Baltimore, MD, 3Mallinckrodt Pharmaceuticals, Bedminster, NJ, 4The Myositis Association, Alexandria, VA, 5Vedanta Research, Chapel Hill, NC

    Background/Purpose: Flare activity or worsening symptoms are not well defined for myositis. This analysis characterizes PM and DM flares from the patient perspective and reports…
  • Abstract Number: 2840 • 2019 ACR/ARP Annual Meeting

    Reliability, Validity and Responsiveness of PROMIS PF-20 in Patients with Inflammatory Myopathy

    Didem Saygin1, Chester Oddis 1, Nicole Neiman 1, Diane Koontz 1, Siamak Moghadam-Kia 1 and Rohit Aggarwal 1, 1University of Pittsburgh Medical Center, Pittsburgh, PA

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are a group of rare, debilitating systemic diseases characterized by proximal muscle weakness, which limit activities of daily living and…
  • Abstract Number: 2844 • 2019 ACR/ARP Annual Meeting

    Predictive Factors for Mortality in Anti-melanoma-associated Gene 5 Antibody-associated Interstitial Lung Disease

    Takahisa Gono1, Kenichi Masui 2, Naoshi Nishina 3, Shinji Sato 4 and Masataka Kuwana 5, 1Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, Tokyo, Japan, 2Department of Anaesthesiology, Show University School of Medicine, Saitama, Japan, 3Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 4Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Yokohama, Japan, 5Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, Bunkyo-ku, Tokyo, Japan

    Background/Purpose: Anti-melanoma differentiation-associated gene 5 (MDA5) antibody is useful to predict mortality in patients with myositis–associated interstitial lung disease (ILD) because of high prevalence of…
  • Abstract Number: 2845 • 2019 ACR/ARP Annual Meeting

    Pain Patterns in Idiopathic Inflammatory Myopathy (IIM): Associations with Disease Activity Measures (Muscle Enzymes, Manual Muscle Testing 8), Patient-Reported Quality of Life (HAQ) and Pain Scales (Widespread Pain Index (WPI), Symptom Severity Index (SSI) and Visual Analogue Scale)

    Elena Schiopu1, Sohail Farshad 2, Nada Abdulaziz 3, Stacey Anderson 3 and Ann Impens 4, 1Department of Rheumatology, University of Michigan, Ann Arbor, 2Department of Internal Medicine, Beaumont Health System, Royal Oak, MI, 3The University of Michigan, Ann Arbor, MI, 4Institute for Healthcare Innovation, Glendale, AZ

    Background/Purpose: IIMs associate with significant lifelong disability due to progressive loss of muscle function and lack of curative interventions; little is known about the relative…
  • Abstract Number: 389 • 2019 ACR/ARP Annual Meeting

    ACR/EULAR Criteria for Myositis and Systemic Sclerosis Lack Sensitivity for Scleromyositis

    Alain Meyer1, Valérie Leclair 2, Océane Landon-Cardinal 3, Benjamin Ellezam 4, Julie D'Aoust 5, Margherita Giannini 6, Bernard Geny 6, Laurent Arnaud 7, Jacques-Eric Gottenberg 8, Jean Sibilia 9, Minoru Satoh 10, Marvin Fritzler 11, Yves Troyanov 12 and Marie Hudson 13, 1Centre de Reference des Maladies Autoimmunes Rares, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, 2Division of Rheumatology, Department of Medicine, Jewish General Hospital; Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Montreal, QC, Canada, 3Centre Hospitalier de l'Université de Montréal, Montréal, Canada, 4Department of Pathology, Centre Hospitalier Universitaire Sainte-Justine, Montréal, Canada, 5McGill University, Montreal, QC, Canada, 6CHU de Strasbourg, Strasbourg, France, 7Service de Rhumatologie, Centre National de Référence des Maladies Autoimmunes Systemiques Rares (RESO), Hôpitaux Universitaires de Strasbourg, Strasbourg, France, Strasbourg, France, 8Department of Rheumatology, Strasbourg University Hospital, Strasbourg, France, 9CHU Strasbourg, Strasbourg, France, 10Department of Clinical Nursing, School of Health Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan, 11Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 12Division of Rheumatology, Department of Medicine, Hôpital du Sacre-Coeur de Montreal, Montreal, QC, Canada, 13Jewish General Hospital, Lady Davis Institute for Medical Research, and Department of Medicine, McGill University, Montreal, QC, Canada

    Background/Purpose: Autoimmune myositis consists of a group of diseases with heterogeneous muscular and systemic manifestations. Prognosis also varies widely across the spectrum. Thus, myositis subgroups…
  • Abstract Number: 399 • 2019 ACR/ARP Annual Meeting

    Seasonal and Temporal Analyses of Disease Onset and Diagnosis in Myositis Autoantibody Phenotypes in Juvenile Dermatomyositis (JDM)

    Gulnara Mamyrova1, Min Shi 2, Ira N. Targoff 3, Rodolfo V. Curiel 1, Frederick W. Miller 4 and Lisa G. Rider 5, 1George Washington University, School of Medicine and Health Sciences, Washington, DC, 2Biostatistics&Computational Biology Branch, NIEHS, NIH, Research Triangle Park, NC, 3Arthritis Immunology Section, Oklahoma Medical Research Foundation, Oklahoma City, OK, 4NIEHS, NIH, Bethesda, MD, 5Environmental Autoimmunity Group, Clinical Research Branch, NIEHS, NIH, Bethesda, MD

    Background/Purpose: Published studies suggest seasonal occurrence of disease onset and disease activity in patients with adult idiopathic inflammatory myopathies (IIM).Our objective was to evaluate seasonal…
  • Abstract Number: 404 • 2019 ACR/ARP Annual Meeting

    Autoantibody Profiles Delineate Three Distinct Subsets of Scleromyositis

    Julie D'Aoust1, Valérie Leclair 2, Geneviève Gyger 3, Alain Meyer 4, Marvin Fritzler 5, Océane Landon-Cardinal 6, Erin O'Ferrall 7, Jason Karamchandani 7, Benjamin Ellezam 8, Rami Massie 7, Minoru Satoh 9, Yves Troyanov 10 and Marie Hudson 11, 1McGill University, Montreal, QC, Canada, 2Division of Rheumatology, Department of Medicine, Jewish General Hospital; Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Montreal, QC, Canada, 3Division of Rheumatology, Department of Medicine, Jewish General Hospital, Montreal, QC, Canada, 4Centre de Reference des Maladies Autoimmunes Rares, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, 5Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 6Division of Rheumatology, Centre hospitalier de l'Université de Montréal; Department of Medicine, Université de Montréal, Montreal, QC, Canada, 7Montreal Neurological Institute, Montreal, QC, Canada, 8Centre hospitalier universitaire Sainte-Justine, Montreal, QC, Canada, 9Department of Clinical Nursing, School of Health Sciences, University of Occupational and Environmental Health, Kitakyushu, Japan, 10Division of Rheumatology, Department of Medicine, Hôpital du Sacre-Coeur de Montreal, Montreal, QC, Canada, 11Jewish General Hospital, Lady Davis Institute for Medical Research, and Department of Medicine, McGill University, Montreal, QC, Canada

    Background/Purpose: Myopathy is an important cause of morbidity in systemic sclerosis (SSc).  Nevertheless, scleromyositis remains incompletely characterized owing at least in part to its clinical…
  • Abstract Number: 881 • 2019 ACR/ARP Annual Meeting

    Auto-antibodies Targeting Components of Sarcolemma Repair: A Pathogenic Mechanism in Human Inflammatory Myopathies

    Kevin McElhanon1, Ana Capati 2, Nicholas Young 3, Brian Paleo 2, Eric Beck 2, Zarife Sahenk 4, Rohit Aggarwal 5, Chester Oddis 5, Noah Weisleder 1 and Wael Jarjour 6, 1Dorothy M. Davis Heart and Lung Research Institute & Dept. of Physiology & Cell Biology, The Ohio State University Wexner Medical Center, Columbus, OH, 2The Ohio State University Wexner Medical Center, Columbus, OH, 3The Ohio State University Wexner Medical Center, Division of Immunology and Rheumatology, Columbus, OH, 4Nationwide Children's Hospital, Columbus, OH, 5University of Pittsburgh Medical Center, Pittsburgh, PA, 6Ohio State College of Medicine, Columbus, OH

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) represent a group of disorders causing chronic inflammation and significant damage to skeletal muscle due to an unchecked autoimmune response. …
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying financial and other sponsors about this policy. If you have questions about the abstract embargo policy, please contact the public relations department at [email protected].

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