ACR Meeting Abstracts

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Abstracts tagged "Myopathies"

  • Abstract Number: 0341 • ACR Convergence 2024

    Efficacy and Safety of Nintedanib in Patients with Idiopathic Inflammatory Myopathy-related Interstitial Lung Disease

    Kaito Aoki1, Keigo Shimura1, Toshiki Ohisa1, Akira Ishii1, Mai Sugiyama2, Yuichiro Ota1, Ayumi Nishikawa3, Noriko Sasaki3, Chiho Yamada1 and Shinji Sato2, 1Tokai University School of Medicine, Isehara, Japan, 2Tokai University, Isehara, Japan, 3Tokai University Hachioji Hospital, Hachioji, Japan

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are chronic inflammatory disorders that affect muscle, skin and lung to varying degrees. Interstitial lung disease (ILD) is a major…
  • Abstract Number: 1645 • ACR Convergence 2024

    Antisynthetase Autoantibodies Disrupt the Function of Their Target Aminoacyl-tRNA Synthetases in Muscle Cells

    Maria Casal-Dominguez1, Iago Pinal-Fernandez2, Sandra Muñoz-braceras3, Corinna preuße4, katherine Pak1, Jiram Torres Ruiz5, Jon Musai1, Stefania Dell'Orso6, Faiza Naz6, Shamima Islam2, Gusatavo Gutierrez-Cruz2, Albert Selva-O’Callaghan7, jose milisenda8, Werner Stenzel9 and Andrew Mammen2, 1National Institutes of health, Bethesda, MD, 2NIH, Bethesda, MD, 3National Institute of Arthritis and Musculoskeletal and Skin Disease, Bethesda, MD, 4Charité - Universitätsmedizin Berlin, Berlin, Germany, 5INCMNSZ, Mexico, Federal District, Mexico, 6National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, Bethesda, MD, 7Systemic Autoimmune Disease Unit, Vall d’Hebron Institute of Research, Barcelona, Spain, 8Hospital Clinic de Barcelona, Barcelona, Spain, 9Charite University, Berlin, Germany

    Background/Purpose: Antisynthetase syndrome (AS) is type of myositis characterized by autoantibodies targeting aminoacyl-transfer tRNA synthetases (aaRSs), the enzymes responsible for loading the appropriate amino acid…
  • Abstract Number: 2086 • ACR Convergence 2024

    Specific Transcriptomic Profile Associated with Disease Activity in Muscle Biopsies from Patients with Sarcoid Myopathy

    Iago Pinal-Fernandez1, Nikolas Ruffer2, Maria Casal-Dominguez3, katherine Pak4, Stefania Dell'Orso5, Faiza Naz5, Shamima Islam6, Gusatavo Gutierrez-Cruz6, Margherita Milone7, Albert selva-O'Callaghan8, jose milisenda9, Felix Kleefeld10, Andrew Mammen6, Teerin Liewluck11 and Werner Stenzel12, 1NIAMS/National Institutes of Health, Bethesda, MD, 2Klinikum Bad Bramstedt, Hamburg, Germany, 3NIAMS, NIH, Bethesda, MD, 4National Institutes of Health, Bethesda, MD, 5National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, Bethesda, MD, 6NIH, Bethesda, MD, 7Mayo Clinic-Rochester, Rochester, MN, 8Systemic Autoimmune Disease Section, Vall d’Hebron Institute of Research, Barcelona, Spain, 9Hospital Clinic de Barcelona, Barcelona, Spain, 10Charité-Universitätsmedizin Berlin, Corporate member of Freie Universität Berlin, Humboldt Universität zu Berlin, and Berlin Institute of Health (BIH), Berlin, Germany, Berlin, Germany, 11Mayo Clinic, Rochester, MN, 12Charite University, Berlin, Germany

    Background/Purpose: Sarcoidosis, a multisystem inflammatory disorder of unknown etiology, exhibits diverse clinical manifestations, with symptomatic musculoskeletal involvement being relatively uncommon but potentially debilitating. We conducted…
  • Abstract Number: 0343 • ACR Convergence 2024

    An Interlaboratory Variability Study of Detection Methods for Myositis-Specific and Myositis-Associated Autoantibodies in Sera from Patients with Idiopathic Inflammatory Myopathies

    Georgina Harvey1, Idil Ashur2, Xavier Bossuyt3, Martin Bluethner4, Anna Brusch5, Chris Bundell5, hector Chinoy6, Claire Coeshott7, Charmaine Donald2, Juliet Dunphy8, Marvin Fritzler9, Adrian Heaps2, marie Hudson10, Masataka Kuwana11, Océane Landon-Cardinal12, Hui Lu1, FIONNUALA MCMORROW1, Marie Mayrhofer4, Alain Meyer13, Birthe Michiels3, Benoit Nespola14, Susan O'Loughlin15, Ivana Putova16, Johan Rönnelid17, Ross Sadler18, Maria Teresa Sanz-Martinez19, Paul Sciore20, Albert Selva-O’Callaghan21, Helena Storfors22, Ernesto Trallero-Araguás23, Yves Troyanov12, Jade Tyson2, Jiří Vencovský24, Akira Yoshida25 and Sarah Tansley1, 1University of Bath, Bath, United Kingdom, 2Severn Pathology, North Bristol NHS Trust, Bristol, United Kingdom, 3University Hospitals Leuven, Leuven, Belgium, 4MVZ Labor PD Dr. Volkmann und Kollegen GbR, Karlsruhe, Germany, 5Department of Clinical Immunology, PathWest Laboratory Medicine, Perth, Western Australia, Australia, 6The University of Manchester, Manchester, United Kingdom, 7Advanced Diagnostics Laboratories National Jewish Health, Denver, CO, 8Royal United Hospital Bath NHS Foundation Trust, Bath, United Kingdom, 9Mitogen Diagnostics Corp, Calgary, AB, Canada, 10McGill University, Montreal, QC, Canada, 11Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan, Tokyo, Japan, 12Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada, 13UR3072, Physiology Department, Rheumatology Department, University Hospital of Strasbourg, Strasbourg, France, 14Laboratoire d’immunologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France, 15Greater Manchester Immunology Service, Manchester, England, United Kingdom, 16Institute of Rheumatology, Prague, Czech Republic, 17Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, 18Laboratory of Immunology, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, England, United Kingdom, 19Immunology Division, Vall d'Hebron Hospital, Barcelona, Spain, 20Mitogen Diagnostics Corp., Calgary, 21Internal Medicine Department, Universitat Autònoma de Barcelona, Barcelona, Spain, 22Department of Clinical Immunology and Transfusion Medicine, Uppsala University Hospital, Uppsala, Sweden, 23Rheumatology Departament, Vall d'Hebron Hospital, Barcelona, Spain, 24Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 25Nippon Medical School Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan

    Background/Purpose: In idiopathic inflammatory myopathy (IIM) spectrum diseases, myositis-specific and myositis-associated autoantibodies (MSAs/MAAs) are key markers of disease subtype and prognosis and are considered routine…
  • Abstract Number: 1731 • ACR Convergence 2024

    Baricitinib in the Treatment of Adult Idiopathic Inflammatory Myopathy: A Randomized, Treatment Delayed-Start Clinical Trial

    hector Chinoy1, Ashma Krishan1, Yvonne Sylvestre1, James Lilleker2, Patrick Gordon3, Sarah Tansley4, Athiveeraramapandian Prabu5, Aamir Aslam6, Andrew Snedden7 and Janine Lamb8, 1The University of Manchester, Manchester, United Kingdom, 2Northern Care Alliance NHS Trust, Salford, United Kingdom, 3nhs, London, United Kingdom, 4University of Bath, Bath, United Kingdom, 5Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, United Kingdom, 6Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 7Northern Care Alliance NHS Foundation Trust, Salford, United Kingdom, 8University of Manchester, UK, Manchester, United Kingdom

    Background/Purpose: The aim of the study was to assess the effects of baricitinib, a JAK1/2 inhibitor, following 24 weeks of active treatment on disease activity…
  • Abstract Number: 2670 • ACR Convergence 2024

    Sera from Patients with Idiopathic Inflammatory Myopathy Induces Muscle Weakness, Mitochondrial Dysfunction and Induction of Cytokines in Isolated Skeletal Muscle

    Cecilia Leijding1, Suchada Kaewin2, Kristofer Andreasson1, Tomas Schiffer1, Angeles Galindo-Feria3, Begum Horuluoglu1, Mattias Carlstrom1, Stefano Gastaldello1, Helene Alexanderson4, Ingrid Lundberg5 and Daniel Andersson6, 1Karolinska Institutet, Stockholm, Sweden, 2Karolinska Institutet, Stockholm, 3Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, 4Karolinska University Hospital, Stockholm, Sweden, 5Karolinska Universitetssjukhuset, Karolinska Institutet, Stockholm, Sweden, 6Karolinska Institutet, Solna, Sweden

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are a group of systemic autoimmune inflammatory muscle disorders characterized by symmetrical skeletal muscle weakness and accelerated fatigue. Although signs…
  • Abstract Number: 1139 • ACR Convergence 2024

    Comprehensive Single-cell Profiling of Diverse Circulating Immune Cells in Idiopathic Inflammatory Myopathies Identifies a Novel Pathogenic Subset of Monocytes

    Shinji Izuka1, Toshihiko Komai2, Hayato Yuuki2, Ikuko Ueda3, Manabu Fujimoto4, Hiroyuki Fukui5, Masaru Takeshita6, Natsuka Umezawa7, Shinsuke Yasuda7, Mitsutaka Yasuda8, Yuichiro Fujieda9, Tatsuya Atsumi9, Takeshi Iwasaki10, Akio Morinobu10, Yuya Kondo11, Isao Matsumoto11, Toshio Kawamoto12, Masakazu Matsushita12, Naoto Tamura13, Taro Iwamoto14, Hiroshi Nakajima14, Ken Yoshida15, Takeo Isozaki16, Nobuyuki Yajima16, Keiichi Sakurai17, Kimito Kawahata17, Yasuyuki Kamata18, Kojiro Sato18, Yoshiya Tanaka19, Akari Suzuki20, Kazuhiko Yamamoto21, Tomohisa Okamura22 and Keishi Fujio2, 1Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Tokyo, Japan, 2Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Bunkyo, Tokyo, Japan, 3Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan., Suita, Japan, 4Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan., Suita, Osaka, Japan, 5Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan., Tokyo, Japan, 6Keio University School of Medicine, Shinjuku-ku, Tokyo, Japan, 7Department of Rheumatology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan., Tokyo, Japan, 8Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan., Sapporo, Japan, 9Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, Sapporo, Japan, 10Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan., Kyoto, Japan, 11Department of Rheumatology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan., Tsukuba, Japan, 12Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo, Japan., Tokyo, Japan, 13Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo, Japan, 14Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan., Chiba, Japan, 15Division of Rheumatology, Department of Internal Medicine, The Jikei University School of Medicine, Tokyo, Japan., Tokyo, Japan, 16Division of Rheumatology, Department of Medicine, Showa University School of Medicine, Tokyo, Japan., Tokyo, Japan, 17Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan., Kawasaki, Japan, 18Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Tochigi, Japan., Tochigi, Japan, 19Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan, 20Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Kanagawa, Japan, 21Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Kawasaki, Japan, 22Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan., Department of Functional Genomics and Immunological Diseases, Graduate School of Medicine, The University of Tokyo, Japan., Bunkyo, Tokyo, Japan

    Background/Purpose: Idiopathic inflammatory myopathies (IIMs) are heterogeneous diseases, making it crucial to identify distinct pathological processes to improve a treatment strategy. Transcriptomic analyses have revealed…
  • Abstract Number: 1965 • ACR Convergence 2024

    Artificial Intelligence Assisted Interpretation of Lung Ultrasound Imaging for the Detection of Interstitial Lung Disease

    Robert Fairchild1, Diane Mar2, Mariani Deluna3, Matthew Baker4, suzanne Tamang5, Henry Guo3, David Fiorentino4 and Lorinda Chung6, 1Stanford University, San Francisco, CA, 2VA Palo Alto / Stanford, Palo Alto, CA, 3Stanford University, Palo Alto, CA, 4Stanford University, Menlo Park, CA, 5Stanford University, Atherton, CA, 6Stanford University, Woodside, CA

    Background/Purpose: Interstitial lung disease (ILD) is a serious complication of SSc and inflammatory myopathy (IM), necessitating accurate and early detection for improved outcomes.  Lung ultrasound…
  • Abstract Number: 1140 • ACR Convergence 2024

    Pulmonary Hypertension in Hospitalized Patients with Dermatomyositis & Polymyositis: A Nationwide Cohort Analysis

    Saman Tanveer1, Daksh Ahluwalia1, Fatima Tanveer2, Abdullah Saeed3, Almurtada Razok4 and Faria Sami5, 1John H. Stroger Jr. Hospital of Cook County, Chicago, IL, 2CMH Lahore Medical and Dental College, Lahore, Pakistan, 3CMH Lahore Medical and Dental College, Lahore, Punjab, Pakistan, 4John H Stroger Jr Hospital of Cook County, Chicago, IL, 5University of Alabama, Chicago, IL

    Background/Purpose: Dermatomyositis (DM) and polymyositis (PM) are idiopathic inflammatory myopathies characterized by muscles inflammation, proximal muscle weakness and extramuscular manifestations. A particularly challenging extramuscular manifestation…
  • Abstract Number: 2052 • ACR Convergence 2024

    Role of Scleroderma/myositis-related Autoantibodies Detected by Immunoblot to the Diagnosis of Systemic Autoimmune Rheumatic Diseases in 410 Patients from a Single Referral Center

    Carmen Secada Gómez1, Diana Prieto-Peña2, Mónica Renuncio-García3, Juan Irure-Ventura4, Marcos Lopez-Hoyos5 and Ricardo Blanco-Alonso6, 1Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, 2Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Cantabria, Spain, 3Division of Immunology, Hospital Universitario Marqués de Valdecilla, Immunopathology Group, IDIVAL, Santander, Spain, 4Division of Immunology, Hospital Universitario Marqués de Valdecilla. Immunopathology group, IDIVAL, Santander, Cantabria, Spain, 5Division of Immunology, Hospital Universitario Marqués de Valdecilla. Immunopathology group, IDIVAL, Santander, Spain, 6Division of Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Immunopathology group, Santander, Spain

    Background/Purpose: In clinical practice, immunoblot assays are being used more frequently as a diagnostic tool for systemic autoimmune rheumatic diseases (SARDs).Our aim was to evaluate the…
  • Abstract Number: 1141 • ACR Convergence 2024

    Defining a Novel Type of Myositis: Immune Mediated Megaconial Myopathy (IMMM)

    Teerin Liewluck1, Ashley Santilli2, Oliver Ni3, Margherita Milone2, Duygu Selcen2, Anahit Mehrabyan4, Arjun Seth5, Christine Hsieh5, Wasim Raslan6, Moayd Alkhalifah6, Raed Alenezi6, Stefan Nicolau7 and Pannathat Soontrapa8, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic-Rochester, Rochester, MN, 3Hennepin Healthcare, Minneapolis, MN, 4University of North Carolina, Chapel Hill, NC, 5Northwestern University, Chicago, IL, 6Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia, 7Nationwide Children’s Hospital, Columbus, OH, 8Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Background/Purpose: To describe a novel type of myositis, immune mediated megaconial myopathy (IMMM),  pathologically characterized by giant mitochondria (megaconia).Methods: We reviewed the Mayo Clinic Muscle…
  • Abstract Number: 2058 • ACR Convergence 2024

    Association of Anti-Synthetase Antibody Subtypes with Radiographic Progression of Interstitial Lung Disease in Anti-Synthetase Syndrome: An Analysis of the CLASS Project Database

    Daphne Rivero Gallegos1, Francisca Bozan2, Sangmee Bae3, Giovanni Zanframundo4, Sara Faghihi-Kashani5, Iazsmin Bauer Ventura6, Eduardo Dourado7, Gianluca sambataro8, Akira Yoshida9, Tamera J Corte10, Francesco Bonella11, Tracy J Doyle12, david fiorentino13, Miguel Angel Gonzalez-Gay14, marie Hudson15, Masataka Kuwana16, Antonella Notarnicola17, Andrew Mammen18, Neil McHugh19, Frederick Miller20, Carlomaurizio Montecucco21, Chester Oddis22, Jorge Rojas-Serrano23, Jens Schmidt24, Carlo A. Scire25, Albert Selva-O’Callaghan26, Victoria Werth27, Rohit Aggarwal28 and Lorenzo Cavagna29, and CLASS project participating investigators, 1INER, Ciudad de México, Mexico State, Mexico, 2Hospital Clinico Universidad de Chile, Santiago, Chile, 3UCLA, Los Angeles, CA, 4Università di Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, Milano, Italy, 5Division of Immunology and Rheumatology, Stanford University School of Medicine, Stanford, CA, San Francisco, CA, 6University of Chicago, Chicago, IL, 7Unidade Local de Saúde da Região de Aveiro, Aveiro, Portugal, 8University of Catania, Catania, Italy, 9Nippon Medical School Graduate School of Medicine, Bunkyo-ku, Tokyo, Japan, 10Royal Prince Alfred Hospital, University of Sydney, Sydney, Australia, 11Center for interstitial and rare lung diseases, Ruhrlandklinik, University of Duisburg-Essen, Essen, Germany, 12Brigham and Women's Hospital, West Roxbury, MA, 13Department of Dermatology, Stanford University School of Medicine, Stanford, CA, Palo Alto, CA, 14University of Cantabria, Fundación Jimenez Díaz, Madrid, Madrid, Spain, 15McGill University, Montreal, QC, Canada, 16Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan, Tokyo, Japan, 17Karolinska University Hospital and Karolinska Institutet, Stockholm, Stockholms Lan, Sweden, 18NIH, Bethesda, MD, 19University of Bath, Bath, United Kingdom, 20NIH, NIEHS, Chapel Hill, NC, 21IRCCS policlinico S. Matteo foundation, University of Pavia, Pavia, Italy, 22Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 23National Institute of Respiratory Diseases, Ismael Cosío Villegas, Mexico City, Mexico, 24University Medical Center Goettingen, Göttingen, Germany, 25University of Milano Bicocca, Milan, Italy, 26Systemic Autoimmune Disease Unit, Vall d’Hebron Institute of Research, Barcelona, Spain, 27University of Pennsylvania, Wynnewood, PA, 28Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, 29University of Pavia and Fondazione IRCCS Policlinico San Matteo Hospital of Pavia, Pavia, Pavia, Italy

    Background/Purpose: In anti-synthetase syndrome (ASSD), clinical presentations vary from isolated interstitial lung disease (ILD) to systemic multi-organ manifestations. Several studies emphasize the crucial role of…
  • Abstract Number: 1144 • ACR Convergence 2024

    Autoantibody and Radiological Profiles as Prognostic Indicators in Idiopathic Inflammatory Myopathies: Insights into Mortality and Interstitial Lung Disease Development

    cristiana sieiro santos1, Miriam Retuerto2, Laura Sierra2, Jose Ordas Martínez3, Paula Pérez García2, Pedro Baenas2, Clara Moriano Morales2 and Elvira Díez Álvarez4, 1Rheumatology Department, Complejo Asistencial Universitario de León, León, Spain, Leon, Spain, 2Complejo Asistencial Universitario de León, León, Spain, 3Complejo Asistencial Universitario de Leon, Leon, 4Complejo Asistencial Universitario de León, Leon, Spain

    Background/Purpose: The idiopathic inflammatory myopathies (IIMs) constitute a diverse group of acquired muscle disorders, often involving multiple organs such as the skin, heart, and lungs.…
  • Abstract Number: 2059 • ACR Convergence 2024

    The Rs35705950 Promoter Variant of Muc5b Is Associated with Usual Interstitial Pneumonia in Antisynthetase Syndrome

    Daphne Rivero Gallegos1, Mayra Mejía2, Karol J. Nava-Quiroz2, Heidegger N. Mateos-Toledo3, Héctor I. Rocha-González4, Juan C. Huerta-Cruz3, Espiridion Ramos-Martínez5, Gloria Pérez-Rubio3, Ingrid Fricke-Galindo3, Jorge Rojas-Serrano6 and Ramcés Falfán-Valencia3, 1INER, Ciudad de México, Mexico State, Mexico, 2INER, Mexico, Distrito Federal, Mexico, 3INER, Mexico City, Distrito Federal, Mexico, 4Instituto Politècnico Nacional, Mexico City, Distrito Federal, Mexico, 5UNAM, Ciudad de Mexico, Distrito Federal, Mexico, 6National Institute of Respiratory Diseases, Ismael Cosío Villegas, Mexico City, Mexico

    Background/Purpose: Rs35705950 variant in the MUC5B gene promoter is a critical genetic risk factor in idiopathic pulmonary fibrosis (IPF). It has been associated with usual…
  • Abstract Number: 1146 • ACR Convergence 2024

    Impact of COVID-19 on Myositis Testing Trends

    Angel Kevin Garza-Elizondo1, Rosa Icela Arvizu-Rivera2, Pablo Gamez-Siller3, Daniela Alejandra Salcedo-Soto4, Jesus Cardenas-de la Garza5, Gisela Garcia-Arellano6, Miguel Angel Villarreal-Alarcon2 and Dionicio Galarza-Delgado7, 1Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, San Nicolás de los Garza, Mexico, 2Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 3Facultad de Medicina UANL, Monterrey, Nuevo León, Mexico, 4Hospital Universitario Dr Jose Eleuterio Gonzalez, Monterrey, Mexico, 5Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 6Hospital Universitario \"Dr. José Eleuterio González\", Monterrey, Nuevo León, Mexico, 7UANL Hospital Universitario, Monterrey, Nuevo León, Mexico

    Background/Purpose: Idiopathic inflammatory myopathies (IIM), also known as myositis, are a group of heterogeneous autoimmune disorders that lead to muscle injury. Autoantibodies help make the…
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