ACR Meeting Abstracts

ACR Meeting Abstracts

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Abstracts tagged "microbiome"

  • Abstract Number: 2701 • 2015 ACR/ARHP Annual Meeting

    An Expansion of Rare Lineage Intestinal Microbes Characterize Rheumatoid Arthritis

    Jun Chen1, John M. Davis III2, Eric L. Matteson3 and Veena Taneja4, 1Health Sciences Research, Mayo Clinic, Rochesert, MN, 2Division of Rheumatology, Mayo Clinic, Rochester, MN, 3Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 4Immunology, Mayo Clinic, Rochester, MN

    Background/Purpose: The adaptive immune response in Rheumatoid arthritis (RA) is influenced by an interaction between host genetics and environment, particularly the host microbiome. To define…
  • Abstract Number: 1153 • 2015 ACR/ARHP Annual Meeting

    Colonic Intraepithelial Lymphocytes Produce IL-6 in Response to Resident Bacteria to Modulate Epithelial Barrier Function

    Gaurav Mehta1, Emilie H. Regner2, Neha Ohri2, Sean P. Colgan2 and Kristine A. Kuhn2, 1Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, 2University of Colorado School of Medicine, Aurora, CO

    Background/Purpose:  Dysbiosis of colon bacteria has emerged as a likely contributor to diseases such as rheumatoid arthritis and spondyloarthropathies. Interactions between the microbiota and distal…
  • Abstract Number: 2740 • 2014 ACR/ARHP Annual Meeting

    Microbiota Modulate Intraepithelial Lymphocyte Presence and Function

    Kristine A. Kuhn and Sean P. Colgan, University of Colorado School of Medicine, Aurora, CO

    Background/Purpose: Microbiome studies in autoimmune diseases including rheumatoid arthritis and inflammatory bowel disease demonstrate alterations in relative abundance of specific bacterial species (dysbiosis). The immunologic…
  • Abstract Number: 622 • 2014 ACR/ARHP Annual Meeting

    Gut Microbiota Variations Correlate with Disease Activity in Spondyloarthritis (SpA) and Rheumatoid Arthritis (RA)

    Julien Tap1,2, Jad Abou-Ghantous1, Ariane Leboime3, Roula Said Nahal3, Philippe Langella1, Henri-Jean Garchon4, Gilles Chiocchia5, Jean-Pierre Furet1 and Maxime Breban3,4, 1UMR INRA-AgroParisTech 1319, Equipe ProbiHote, MICALIS Institute, National Institute for Agronomical research (INRA), Jouy-en-Josas, France, 2Metagenopolis, INRA, Jouy-en-Josas, France, 3Service de Rhumatologie, Hopital Ambroise Pare, Boulogne-Billancourt, France, 4INSERM U987, Faculté des Sciences de la Santé Simone Veil, Montigny-le-Bretonneux, France, 5Versailles Saint Quentin en Yvelines University, INSERM U987, UFR des Sciences de la Santé, Montigny-le-Bretonneux, France

    Background/Purpose Inflammatory bowel diseases (IBD) are associated with changes in microbiota which may be responsible for sustained gut inflammation and/or a consequence of it. Whether…
  • Abstract Number: 618 • 2014 ACR/ARHP Annual Meeting

    A Gender Bias in Gut Microbiota of SKG Mice Colonized with a Limited Bacterial Consortium Associated with Severity of Spondyloarthritis and Ileitis Triggered By Beta-Glucan

    Linda Rehaume, Olga Zbarskaya, Alicia Kang, Helen Benham, Paraic O Cuiv, Mark Morrison and Ranjeny Thomas, University of Queensland Diamantina Institute, Brisbane, Australia

    Background/Purpose Beta-glucan (curdlan)-treated BALB/c ZAP-70W163C(SKG) mutant mice develop IL-23-dependent spondyloarthritis, and curdlan promotes ileitis in SKG mice housed under specific pathogen-free (SPF) but not germ-free…
  • Abstract Number: 88 • 2014 ACR/ARHP Annual Meeting

    Microbiomes of Inflammatory and Non-Inflammatory Thoracic Aortic Aneurysms

    Pauline Funchain*1,2,3, Gary S. Hoffman*4, Lars Svensson5, Eric Roselli5, Gosta Pettersson6, Douglas Johnston6, Edward Soltesz6, Ritu Chakravarti7, Alison Clifford8 and Charis Eng2, 1Genomic Medicine Institute, Lerner Research Institute, Cleveland, OH, 2Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, 3Taussig Cancer Institute, Cleveland Clinic Foundation, Cleveland, OH, 4Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, OH, 5Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, OH, 6Thoracic and Cardiovascular Surgery, Cleveland Clinic Foundation, Cleveland, OH, 7Lerner Research Institure, Cleveland Clinic, Cleveland, OH, 8Rheumatic and Immunologic Diseases, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Aortitis may occur in the context of multifocal large and medium-sized vessel diseases such as giant cell arteritis (GCA) or Takayasu arteritis (TAK) and…
  • Abstract Number: 1165 • 2013 ACR/ARHP Annual Meeting

    Systems Approach To The Study Of the Microbiome and Inflammatory Pathways In Oral Ulcer Tissue From Patients With Active Behςet’s Syndrome (BS)

    Cailin Sibley1, Gulen Hatemi2, Yusuf Yazici3, Yin Liu4, Steve Brooks5, Hasan Yazici6 and Raphaela Goldbach-Mansky7, 1Office of the Clinical Director, NIH / NIAMS, Bethesda, MD, 2Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 3Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 4Translational Autoinflammatory Disease Section, Office of the Clinical Director, NIAMS/NIH, Bethesda, MD, 5NIAMS/NIH, Bethesda, MD, 6Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey, 7Translational Autoinflammatory Diseases Section, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, MD

    Background/Purpose: Behcet's syndrome (BS) exhibits features of both innate and acquired immunity.   Oral ulceration is the cardinal lesion which usually precedes other manifestations.  Despite the…
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ACR Convergence: Where Rheumatology Meets. All Virtual. November 5-9.

ACR Pediatric Rheumatology Symposium 2020

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