Abstracts tagged "Magnetic resonance imaging (MRI)"

Abstract Number: 1948 • ACR Convergence 2025
Enhanced Prediction of Knee Osteoarthritis Progression through Deep Learning-Based Multimodal Data Fusion
Daniela Herrera¹, Ahmad Almhdie-Imjabbar², Hechmi Toumi³ and Eric Lespessailles⁴, ¹PRIMMO- University Hospital Center of Orleans, Olreans, France, ²University Hospital Center of Orleans, Orleans, France, ³PRIMMO- University Hospital Center of Orleans, Orleans, France, ⁴CHU Orléans, Orléans, France
Background/Purpose: Effective diagnosis and management of knee osteoarthritis (KOA) increasingly rely on integrating diverse data sources, including imaging and clinical information. The practice of combining…
Abstract Number: 0428 • ACR Convergence 2025
The OMERACT Juvenile Idiopathic Arthritis MRI Score for Active and Structural Lesions in the Sacroiliac Joints: Development and Validation in Two Longitudinal Cohorts
Walter P. Maksymowych¹, Michael Francavilla², Nele Herregods³, Robert G. W. Lambert⁴, Arthur Meyers⁵, Joel Paschke⁶, Jennifer Stimec⁷, Pamela Weiss⁸ and Dax Rumsey⁹, ¹Department of Medicine, University of Alberta, ⁵⁶⁸ Heritage Building, Edmonton, AB, Canada, ²Department of Pediatric Radiology, Children’s Hospital Philadelphia, Philadelphia, PA, ³Department of Pediatric Radiology, Ghent University Hospital, Ghent, Belgium, ⁴University of Alberta, Department of Radiology & Diagnostic Imaging, Edmonton, AB, Canada, ⁵Department of Radiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ⁶CARE Arthritis Limited, Edmonton, AB, Canada, ⁷Department of Diagnostic Imaging, SickKids, University of Toronto, Toronto, Canada, ⁸Childrens Hospital of Philadelphia, Philadelphia, PA, ⁹Department of Pediatrics, University of Alberta, Edmonton, AB, Canada
Background/Purpose: The OMERACT Juvenile Idiopathic Arthritis MRI (JAMRIS) Working group has defined a spectrum of MRI lesions in the sacroiliac joint (SIJ) in youth with…
Abstract Number: 2677 • ACR Convergence 2025
Quantified Imaging Response at the Sacroiliac Joints to TNF-Inhibitor Therapy in Youth with Axial Disease
Timothy Brandon¹, Rui Xiao², Daniel Lovell³, Edward Oberle⁴, Matthew Stoll⁵, Nancy A. Chauvin⁶, Michael Francavilla⁷, Walter P. Maksymowych⁸ and Pamela Weiss⁹, ¹Children's Hospital of Philadelphia, Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Nationwide Children's Hospital, Columbus, OH, ⁵University of Alabama at Birmingham, Birmingham, AL, ⁶The Cleveland Clinic, Hummelstown, PA, ⁷Department of Pediatric Radiology, Children’s Hospital Philadelphia, Philadelphia, PA, ⁸Department of Medicine, University of Alberta, ⁵⁶⁸ Heritage Building, Edmonton, AB, Canada, ⁹Childrens Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: This study assessed the timeline for the resolution of inflammation, changes in structural lesions at the sacroiliac joints (SIJ), and their correlation with patient-reported…
Abstract Number: 1945 • ACR Convergence 2025
Significance of Finger Joint Tenderness With or Without Swelling in Relation to MRI, Ultrasound, and X-Ray Findings in Psoriatic Arthritis_Final results
Victoria Furer¹, iris Eshed², Moshe Iluz¹, Ori Elkayam³ and Ari Polachek⁴, ¹Tel-Aviv Medical Center, Tel-Aviv, Israel, ²Department of Diagnostic Imaging, Sheba Medical Center, Tel Hashomer affiliated with School of Medicine, Tel Aviv University, Tel Aviv, Israel, ³Tel Aviv medical center, Tel Aviv, Israel, ⁴Rheumatology Institute of Beilinson Hospital, Petah Tikva, Israel
Background/Purpose: Musculoskeletal involvement in psoriatic arthritis (PsA) affects both articular and extra-articular structures, presenting as inflammatory and structural lesions. The relationship between tender and/or swollen…
Abstract Number: 0390 • ACR Convergence 2025
Radiographic Assessment in Juvenile Spondyloarthritis: Evaluating the axJSpA Criteria Using Radiographs Alone Versus MRI
David M. Biko¹, Nancy A. Chauvin², Michael Francavilla³, Nele Herregods⁴, Walter P. Maksymowych⁵, Robert G. W. Lambert⁶, Timothy Brandon¹, Ozgur Kasapcopur⁷, Mehmet YILDIZ⁸, Hemalatha Srinivasalu⁹ and Pamela Weiss¹⁰, ¹Children's Hospital of Philadelphia, Philadelphia, PA, ²The Cleveland Clinic, Hummelstown, PA, ³Department of Pediatric Radiology, Children’s Hospital Philadelphia, Philadelphia, PA, ⁴Ghent University Hospital, Ghent, Belgium, ⁵Department of Medicine, University of Alberta, ⁵⁶⁸ Heritage Building, Edmonton, AB, Canada, ⁶University of Alberta, Department of Radiology & Diagnostic Imaging, Edmonton, AB, Canada, ⁷Istanbul University-Cerrahpasa, Cerrahpasa Medical School, istanbul, Turkey, ⁸Istanbul University-Cerrahpasa Department of Pediatric Rheumatology, Istanbul, Turkey, ⁹Children's National Hospital, Washington, DC, ¹⁰Childrens Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Radiographs are neither sensitive nor reliable for assessing axial disease in juvenile spondyloarthritis (JSpA), though they are still used in some settings due to…
Abstract Number: 2635 • ACR Convergence 2025
Differences in structural lesions of the spine between patients with early axSpA and non-axSpA chronic back pain: 2-year results of the SPACE Cohort
Gizem Ayan¹, Liese de Bruin², Miranda van Lunteren², Manouk de Hooge³, Ana Bento da Silva², Mary Lucy Marques⁴, Monique Reijnierse⁵, Victoria Navarro-Compan⁶, Marleen van de sande⁷, Inger Jorid Berg⁸, Roberta Ramonda⁹, Sofia Exarchou¹⁰, Désirée Van Der Heijde², Floris A. van Gaalen² and Sofia Ramiro¹¹, ¹Ankara Research and Training Hospital, Ankara, Turkey, ²Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Rheumatology, Ghent University Hospital, Ghent, Belgium, ⁴Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands; and Coimbra Local Health Unit, Coimbra, Portugal, ⁵Department of Radiology, Leiden University Medical Center, Leiden, Netherlands, ⁶Department of Rheumatology, La Paz University Hospital, IdiPaz, Madrid, Spain, ⁷The Department of Rheumatology and Clinical Immunology, Amsterdam University Medical Center, Amsterdam, Netherlands, ⁸Center for Treatment of Rheumatic and Musculoskeletal Diseases (REMEDY), Diakonhjemmet Hospital, Oslo, Norway, ⁹Rheumatology Unit-DIMED-University of Padova ITALY, Padova, Padua, Italy, ¹⁰Lund University, Åkarp, Skane Lan, Sweden, ¹¹Leiden University Medical Center, Bunde, Netherlands
Background/Purpose: The difference in spinal structural lesions and their progression over time between chronic back pain (CBP) patients with and without early axSpA is unknown.…
Abstract Number: 1937 • ACR Convergence 2025
Does Combining Standard MRI-Based Scores with Radiographic Trabecular Bone Texture Biomarkers Improve Predictive Performance for Radiographic Knee Osteoarthritis Progression?
Ahmad Almhdie-Imjabbar¹, Saida Daroussi², Daniela Herrera³, Hechmi Toumi² and Eric Lespessailles⁴, ¹University Hospital Center of Orleans, Orleans, France, ²PRIMMO- University Hospital Center of Orleans, Orleans, France, ³PRIMMO- University Hospital Center of Orleans, Olreans, France, ⁴CHU Orléans, Orléans, France
Background/Purpose: Knee osteoarthritis (KOA) is a major cause of disability worldwide, particularly impacting the elderly and obese population. Radiographic trabecular bone texture (TBT) is demonstrated…
Abstract Number: 0323 • ACR Convergence 2025
Automated Effusion-Synovitis Volume is Prognostic and Responsive to Knee Osteoarthritis Progression: Data from the Osteoarthritis Initiative
Jeffrey Driban¹, Kate Lapane², Shao-Hsien Liu², Jonggyu Baek², Grace Lo³, Matthew Harkey⁴, Charles Eaton⁵, James Mackay⁶, Timothy McAlington⁷, Mohammad Chowdhury⁸, Zhen Cao⁹, Juan Shan¹⁰ and Ming Zhang¹¹, ¹University of Massachusetts Chan Medical School, Marlborough, NH, ²UMass Chan Medical School, Worcester, MA, ³Baylor College of Medicine / MEDVAMC, Houston, TX, ⁴Michigan State University, East Lansing, MI, ⁵Brown University, Pawtucket, RI, ⁶University of Cambridge; Norwich Medical School, San Diego, CA, ⁷UMass Chan School of Medicine, Arlington, MA, ⁸Pace University, New York City, NY, ⁹Boston University, Boston, MA, ¹⁰Pace University, New York, NY, ¹¹Boston University, Westford, MA
Background/Purpose: Semi-quantitative and semi-automated quantitative measurements of effusion-synovitis (ES) are prognostic for knee OA progression. Changes in these metrics relate to changes in knee pain.…
Abstract Number: 2625 • ACR Convergence 2025
Early Detection of Knee Osteoarthritis – The Role of a Composite Disease Activity Metric: Data from the Osteoarthritis Initiative
Julieann Patarini¹, Timothy McAlington², Jonggyu Baek¹, Emily Kirillov³, Nhung Vo³, Michael Richard³, Ming Zhang⁴, Matthew Harkey⁵, Grace Lo⁶, Shao-Hsien Liu¹, Kate Lapane¹, Charles Eaton⁷, James Mackay⁸ and Jeffrey Driban⁹, ¹UMass Chan Medical School, Worcester, MA, ²UMass Chan School of Medicine, Arlington, MA, ³Tufts Medical Center, Boston, MA, ⁴Boston University, Westford, MA, ⁵Michigan State University, East Lansing, MI, ⁶Baylor College of Medicine / MEDVAMC, Houston, TX, ⁷Brown University, Pawtucket, RI, ⁸University of Cambridge; Norwich Medical School, San Diego, CA, ⁹University of Massachusetts Chan Medical School, Marlborough, NH
Background/Purpose: Bone marrow lesions (BMLs) and effusion-synovitis are frequent and dynamic disease processes detected from early- to late-stage knee OA. These processes are associated with…
Abstract Number: 1854 • ACR Convergence 2025
Resting-State Functional Magnetic Resonance Imaging Analysis Revealed Altered Functional Connectivity Associated with Fatigue in Systemic Lupus Erythematosus
Yujie Song¹, Nobuya Abe¹, Yuichiro Fujieda², Kodai Sakiyama¹, Yuta Inoue¹, Kenichi Miyamoto¹, Kazuro Kamada¹, Yotaro Oki¹, Maria Tada¹, Shuhei Takeyama¹, Ryo Hisada², Michihito Kono² and Tatsuya Atsumi², ¹Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan, ²Department of Rheumatology, Endocrinology and Nephrology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Hokkaido, Japan
Background/Purpose: Fatigue is one of the most frequent constitutional symptoms in systemic lupus erythematosus (SLE), usually accompanied with impaired quality of life. Resting-state functional magnetic…
Abstract Number: 0309 • ACR Convergence 2025
A Composite Cumulative Cartilage Damage Metric Predicts Incident Symptomatic Knee OA: Data from the Osteoarthritis Initiative
Julieann Patarini¹, Timothy McAlington², Jonggyu Baek¹, Emily Kirillov³, Nhung Vo³, Michael Richard³, Ming Zhang⁴, Matthew Harkey⁵, Grace Lo⁶, Shao-Hsien Liu¹, Kate Lapane¹, Charles Eaton⁷, James Mackay⁸ and Jeffrey Driban⁹, ¹UMass Chan Medical School, Worcester, MA, ²UMass Chan School of Medicine, Arlington, MA, ³Tufts Medical Center, Boston, MA, ⁴Boston University, Westford, MA, ⁵Michigan State University, East Lansing, MI, ⁶Baylor College of Medicine / MEDVAMC, Houston, TX, ⁷Brown University, Pawtucket, RI, ⁸University of Cambridge; Norwich Medical School, San Diego, CA, ⁹University of Massachusetts Chan Medical School, Marlborough, NH
Background/Purpose: Cartilage defects are a hallmark of OA progression. We previously developed a composite MRI-based metric that combines cartilage damage from 6 anatomical regions throughout…
Abstract Number: 2623 • ACR Convergence 2025
Disease Activity is a Novel Imaging Biomarker Associated with Knee Pain: Data from the Osteoarthritis Initiative
Jeffrey Driban¹, Jonggyu Baek², Julieann Patarini², Emily Kirillov³, Nhung Vo³, Michael Richard³, Ming Zhang⁴, Matthew Harkey⁵, Grace Lo⁶, Kate Lapane², Shao-Hsien Liu², Charles Eaton⁷, James Mackay⁸, Joshua Harvey² and Timothy McAlington⁹, ¹University of Massachusetts Chan Medical School, Marlborough, NH, ²UMass Chan Medical School, Worcester, MA, ³Tufts Medical Center, Boston, MA, ⁴Boston University, Westford, MA, ⁵Michigan State University, East Lansing, MI, ⁶Baylor College of Medicine / MEDVAMC, Houston, TX, ⁷Brown University, Pawtucket, RI, ⁸University of Cambridge; Norwich Medical School, San Diego, CA, ⁹UMass Chan School of Medicine, Arlington, MA
Background/Purpose: Barriers to developing effective osteoarthritis (OA) therapies include the lack of standardized definitions for disease progression and structural endpoints that reliably predict changes in…
Abstract Number: 1496 • ACR Convergence 2025
Demyelinating Syndromes in Systemic Lupus Erythematosus: A 23-Year Retrospective Analysis of Clinical Features and Treatment Outcomes from a Tertiary Care Center
Manikandan Gopal¹, Ashish Jacob Mathew² and john mathew³, ¹christian medical college, Vellore, India, ²Christian Medical College, Vellore, Tamil Nadu, India, ³Christian Medical college , Vellore , India, Vellore, Tamil Nadu, India
Background/Purpose: Systemic Lupus Erythematosus (SLE) with acute myelitis or optic neuritis is rare and causes significant morbidity. Data on these conditions remain limited. This study…
Abstract Number: 0242 • ACR Convergence 2025
Contemporary Recurrent Pericarditis Management – Real-world Evidence of Limited Cardiac Magnetic Resonance Imaging Prior to Initiating Rilonacept
Brittany Weber¹, Paul Cremer², Michael Garshick³, Sushil Allen Luis⁴, Ajit Raisinghani⁵, Vidhya Parameswaran⁶, Allison Curtis⁶, Allan Klein⁷ and John Paolini⁶, ¹Brigham and Women's Hospital, DEDHAM, MA, ²Cleveland Clinic, Shaker Heights, OH, ³NYU Langone Health, Tenafly, NJ, ⁴Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, ⁵Division of Cardiology, Department of Medicine, Sulpizio Cardiovascular Center, University of California San Diego, San Diego, CA, ⁶Kiniksa Pharmaceuticals, LEXINGTON, MA, ⁷Cleveland Clinic, Cleveland, OH
Background/Purpose: Recurrent pericarditis (RP) is a chronic autoinflammatory disease (mediated by IL-1) that requires long-term treatment, and selection of therapy is guided by multiple factors.…
Abstract Number: 2614 • ACR Convergence 2025
Impact of Vagus Nerve-Mediated Neuroimmune Modulation on structural joint damage using Gd-MRI RAMRIS imaging in Biologic-Experienced Patients with Rheumatoid Arthritis
Charles Peterfy, MD, PhD¹, John Tesser², Yaakov Levine³, Melissa Evangelista⁴, Vibeke Strand⁵, Michael Weinblatt⁶ and David Chernoff⁷, ¹Spire Sciences, Inc., Boca Raton, FL, ²Arizona Arthritis & Rheumatology Associates, Phoenix, AZ, ³SetPoint Medical, Valencia, CA, ⁴SetPoint Medical Corporation, Valencia, CA, ⁵Stanford University School of Medicine, Palo Alto CA, Portola Valley, CA, ⁶Brigham and Women's Hospital/ Harvard Medical School, Waban, MA, ⁷SetPoint Medical, Sausalito, CA
Background/Purpose: Previously reported results from RESET-RA (ClinicalTrials.gov, NCT04539964) showed neuroimmune modulation via electrical stimulation of the left vagus nerve using an implantable device to treat…

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