ACR Meeting Abstracts

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Abstracts tagged "longitudinal studies"

  • Abstract Number: 1539 • ACR Convergence 2024

    Effectiveness & Safety of Early versus Late Use of Rituximab in Extra-renal Lupus: Real World Experience from a Tertiary Care Centre

    JOHN KUMAR DAS1, ABHILASHA ARVIND MANWATKAR2 and JOHN MATHEW2, 1Christian Medical College, Vellore, India, 2christian medical college, vellore, Tamil Nadu, India

    Background/Purpose: Rituximab, a monoclonal antibody targeting CD20 positive B cells failed to show effectiveness in SLE, including EXPLORER and LUNAR trials.However, real world data in…
  • Abstract Number: 2571 • ACR Convergence 2024

    Trajectories of Physical Function in Children with Juvenile Idiopathic Arthritis: Results from the CAPRI Registry

    Clare Cunningham1, Roberta A Berard2, Matthew Berkowitz3, Brian Feldman4, Nicole Johnson5, Lillian Lim6, Thomas Loughin3, Meghan McPherson7, Paivi Miettunen5, Jean-Philippe Proulx-Gauthier8, Dax Rumsey6, Heinrike Schmeling5, Lori Tucker9, Kristin Houghton10 and Jaime Guzman11, and CAPRI Registry Investigators, 1University of British Columbia, Vancouver, BC, Canada, 2London Health Sciences Centre, London, ON, Canada, 3Simon Fraser University, Burnaby, BC, Canada, 4Division of Rheumatology, The Hospital for Sick Children; Departments of Pediatrics and Medicine, Faculty of Medicine; The Institute for Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, 5University of Calgary, Calgary, AB, Canada, 6University of Alberta, Edmonton, AB, Canada, 7University of Manitoba, Winnipeg, MB, Canada, 8CHU de Quebec - Universite Laval, Quebec, QC, Canada, 9BC Children's Hospital, Vancouver, BC, Canada, 10University of British Columbia - Vancouver, Vancouver, BC, Canada, 11University of British Columbia and BC Children's Hospital, Vancouver, BC, Canada

    Background/Purpose: Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease of childhood. Contrary to historical cohorts, it is hoped that with contemporary treatments…
  • Abstract Number: 1472 • ACR Convergence 2023

    Prevalence of Hepatic Injury in Patients with Systemic Lupus Erythematosus: A 28-Year Single Center Experience

    Asif Hitawala1, Zerai Manna2, Yenealem Temesgen-Oyelakin3, Elaine Poncio3, Christopher Koh4, sarfaraz Hasni2 and Theo Heller4, 1NIDDK/NIH, Bethesda, MD, 2Lupus Clinical Trials Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH), Bethesda, MD, 3National Institute of Arthritis and Musculoskeletal and Skin Diseases, Bethesda, MD, 4NIDDK/Liver disease branch, Bethesda, MD

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) are known to have hepatic injury (HI), however large-scale longitudinal studies are lacking.We report our experience of HI…
  • Abstract Number: 1488 • ACR Convergence 2023

    Association of Glucocorticoid Use with Patient-Reported Outcomes Among Persons with Systemic Lupus Erythematosus

    Patti Katz1, Sofia Pedro2, Jiyoon Choi3 and Kaleb Michaud4, 1University of California San Francisco, San Rafael, CA, 2Forward, The National Databank for Rheumatic Diseases, Wichita, KS, 3Bristol Myers Squibb, Lawrenceville, NJ, 4University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Glucocorticoids (GCs) have long been a mainstay of treatment for SLE. While GCs do provide benefit, there are potential side effects that increase with…
  • Abstract Number: 1604 • ACR Convergence 2023

    First and Recurrent Thrombosis Risk After 4,454 Patient-Years of Follow-Up: Prospective Results from the AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) Clinical Database and Repository (“Registry”)

    Jonathan Thaler1, Yasaman Ahmadzadeh2, Danieli Andrade3, leslie skeith4, Maria Tektonidou5, Savino Sciascia6, Vittorio Pengo7, Jose Pardos-Gea8, Guillermo Ruiz-Irastorza9, Chary Lopez-Pedrera10, H Michael Belmont11, Kello Nina12, Paul R. Fortin13, Denis WAHL14, Maria Gerosa15, Guilherme De Jesús16, Zhuoli Zhang17, Tatsuya Atsuma18, Maria Efthymiou19, D. Ware Branch20, Laura Andreoli21, Esther Rodriguez almaraz22, Michelle Petri23, Giulia Pazzola24, Ricard Cervera25, Bahar Artim Esen26, Hui Shi27, Jason Knight27, Guillermo Pons-Estel28, Rohan Willis29, Ali Duarte-Garcia30, Maria Laura Bertolaccini31, Hannah Cohen32, Doruk Erkan1 and On Behalf Of APS ACTION33, 1Hospital for Special Surgery, New York, NY, 2Roger Williams Medical Center, Providence, RI, 3University of São Paulo, São Paulo, Brazil, 4University of Calgary, Calgary, AB, Canada, 5Joint Academic Rheumatology Program, First Department of Propedeutic and Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece, 6University of Turin, Torino, Italy, 7Department of Cardiac-Thoracic-Vascular Sciences and Public Health University of Padova, Padova, Italy, 8Vall d'Hebron University Hospital, Barcelona, Spain, 9Hospital Universitario Cruces, Barakaldo, Spain, 10IMIBIC - Reina Sofia Hospital, Córdoba, Spain, 11NYU School of Medicine, New York, NY, 12Northwell Health, Brooklyn, NY, 13Centre ARThrite - CHU de Québec - Université Laval, Quebec City, QC, Canada, 14University of Lorraine, Nancy, France, 15University of Milan, Milano, Italy, 16Universidade do Estado do Rio de Janeiro, Rio De Janeiro, Brazil, 17Peking University First Hospital, Rheumatology and Immunology Department, Beijing, China, 18Hokkaido University, Department of Rheumatology, Endocrinology and Nephrology, Sapporo, Japan, 19University College London, London, United Kingdom, 20University of Utah, Salt Lake City, UT, 21University of Brescia, Brescia, Italy, 22Hospital Universitario 12 de Octubre, Madrid, Spain, 23Department of Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Timonium, MD, 24Azienda Ospedaliera Santa Maria Nuova di Reggio Emilia, Reggio Emilia, Italy, 25Hospital Clínic de Barcelona, Barcelona, Spain, 26Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, 27University of Michigan, Ann Arbor, MI, 28CREAR, Rosario, Argentina, 29University of Texas Medical Branch, Galveston, TX, 30Mayo Clinic, Rochester, MN, 31King's College London, London, United Kingdom, 32University College London Hospitals NHS Foundation Trust, London, United Kingdom, 33on behalf of APS ACTION, New York, NY

    Background/Purpose: The APS ACTION Registry was created to study the natural course of disease over 10 years in persistently antiphospholipid antibody (aPL)-positive patients with or…
  • Abstract Number: 1696 • ACR Convergence 2023

    Multi-Omic Profiling Reveals Immune Cell Priming Signature Linked to Systemic Lupus Erythematosus Prognosis

    Michael A. Smith1, Dominic Sinibaldi2, Saifur Rahman1, Chia-Chien Chiang2, Anna M. Hansen1, Jill Henault1, Carlos P. Roca3, Shu Wang1, Kamelia Zerrouki1, Rebecca Filippi1, Christopher Groves1, Zerai Manna4, Jun Chu4, Michael Davis4, sarthak gupta4, Christopher Morehouse1, Melissa De los Reyes1, Rachel Ettinger1, Roland Kolbeck1, Mariana Kaplan5, Miguel A. Sanjuan1, Richard M. Siegel6, sarfaraz Hasni4 and Kerry A. Casey1, 1BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, 2Data Science and AI, AstraZeneca, Gaithersburg, MD, 3Data Science and AI, AstraZeneca, Cambridge, United Kingdom, 4Lupus Clinical Trials Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH), Bethesda, MD, 5Lupus Clinical Trials Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH); Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH), Bethesda, MD, 6Office of the Clinical Director, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health (NIH), Bethesda, MD

    Background/Purpose: Much of our understanding of systemic lupus erythematosus (SLE) immunopathogenesis is derived from gene profiling studies, where core pathways such as neutrophil dysregulation and…
  • Abstract Number: 1768 • ACR Convergence 2023

    The Dynamics of the Gut Microbiome in Rheumatoid Arthritis Susceptibility: A Cross-Sectional and Longitudinal Observational Study

    Christopher Rooney1, Ian Jeffery2, Kulveer Mankia3, Mark Wilcox1 and Paul Emery4, 1University of Leeds, Leeds, United Kingdom, 24D Pharma plc, Cork, Ireland, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose: Multiple compositional shifts of gut microbiota have been identified within the rheumatoid arthritis (RA) disease continuum, encompassing both established RA and at-risk individuals (including…
  • Abstract Number: 1846 • ACR Convergence 2023

    A Longitudinal Study: The Benefits of Non-Pharmacological Approaches to Improve Self-Reported Pain, Stiffness, and Fatigue in Individuals with Musculoskeletal Disorders

    Titilayo Adeniran, Bertilia Trieu, Claudia Zurlini, Bonnie McGrath, Linda Roberts, Pamela Sanchez-Villagomez, Vilma Briones, Robyn Wiesel, Sandra Goldsmith and Laura Robbins, Hospital for Special Surgery, New York, NY

    Background/Purpose: Musculoskeletal disorders are a leading cause of disability worldwide, with low back pain being one of the primary causes. The World Health Organization (WHO)…
  • Abstract Number: 1865 • ACR Convergence 2023

    Is Flexion Contracture in Knee Osteoarthritis Associated with MRI Pathologies over Time? Data from the Osteoarthritis Initiative

    Daniel Chan Chun Kong1, Philip Conaghan2 and Mark Campbell3, 1University of Ottawa, Ottawa, ON, Canada, 2University of Leeds, Leeds, United Kingdom, 3Elisabeth Bruyere Hospital, Ottawa, ON, Canada

    Background/Purpose: Knee flexion contracture (FC) is associated with worse clinical outcomes in those with knee OA. Cross sectional data demonstrated that knee FC was associated…
  • Abstract Number: 0104 • ACR Convergence 2023

    Cluster Analysis of Antiphospholipid Antibodies Associated Adverse Pregnancy Outcome Patients: Based on a 13-year Longitudinal Cohort Study

    Yin Long1, Jiuliang zhao2, Mengtao Li2, Xinping Tian2 and xiaofeng Zeng3, 1Peking Union Medical College Hospital Department of Rheumatology and Clinical Immunology, Beijing, China, 2Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China, 3Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

    Background/Purpose: Antiphospholipid antibodies (aPLs) play a pivotal role in the etiology of adverse pregnancy outcomes (APOs). (1) Women with persistently aPLs positivity present heterogeneous clinical…
  • Abstract Number: 1978 • ACR Convergence 2023

    Infrapatellar Fat Pad Size and Subcutaneous Fat in Knee Osteoarthritis Radiographic Progression: Data from the Osteoarthritis Initiative

    Kwanghoon Lee1, Marina Banuls-Mirete2, Alecio Lombardi3, Alexander Posis3, Eric Chang3, Nancy Lane4 and Monica Guma5, 1Dongguk University ilsan Hospital, San Diego, CA, 2Department of Medicine, University of California San Diego, San Diego, CA, 3University of California San Diego, San Diego, CA, 4University of California, Hillsborough, CA, 5University of California San Diego, La Jolla, CA

    Background/Purpose: Adipose tissue is associated with knee osteoarthritis (KOA) progression. This study aimed to determine the association of infrapatellar fat pad (IPFP) size and subcutaneous…
  • Abstract Number: 0199 • ACR Convergence 2023

    Experience in Real-World Conditions of the Effectiveness of the Vaccine Against Herpes Zoster Virus

    Laura Mas Sanchez1, Pablo Francisco Muñoz Martínez2, Elena Grau Garcia3, Alba Maria Torrat Noves3, Daniel Ramos Castro3, Carmen Riesco Barcena3, Anderson Victor Huaylla Quispe3, Belen Villanueva Mañez3, Iago Alcantara Alvarez3, Samuel Leal Rodriguez3, Marta De la Rubia Navarro1, Ernesto Tovar Sugrañes3, Jose Ivorra Cortes3, Luis Gonzalez Puig3, Rosa Negueroles Albuixech3, Elvira Vicens Bernabeu3, Jose Eloy Oller Rodriguez3, Isabel Martinez Cordellat3, Hikmat Charia3, Ines Canovas Olmos3, Carmen Najera Herranz3 and Jose Andres Roman Ivorra4, 1Rheumatology Department. HUP La Fe, Valéncia, Spain, 2Rheumatology Department. HUP La Fe, Sagunto, Spain, 3Rheumatology Department. HUP La Fe, Valencia, Spain, 4Hospital Universitari i Politècnic la Fe, Valencia, Spain

    Background/Purpose: Herpes zoster infection is due to the reactivation of the varicella-zoster virus (VZV), having a high prevalence in elderly and immunocompromised patients. Since the…
  • Abstract Number: 1979 • ACR Convergence 2023

    Weight Loss Induced by Anti-obesity Medications and All-cause Mortality Among Patients with Knee or Hip Osteoarthritis

    Jie Wei1, david Hunter2, Nancy Lane3, Jing Wu4, Chao Zeng5, Guanghua Lei5 and Yuqing Zhang6, 1Health Management Center, Xiangya Hospital Central South University, Changsha, China, 2Sydney Musculoskeletal Health, University of Sydney, St. Leonards, Australia, 3University of California, Hillsborough, CA, 4Key Laboratory of Aging-related Bone and Joint Diseases Prevention and Treatment, Ministry of Education, Xiangya Hospital, Central South University, Changsha, China, 5Department of Orthopaedics, Xiangya Hospital, Central South University, Changsha, China, 6Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Boston, MA

    Background/Purpose: The current international guidelines recommend weight loss for pain relief and functional improvement in overweight or obese patients with knee or hip osteoarthritis; however,…
  • Abstract Number: 0546 • ACR Convergence 2023

    Markers of Oxidative Stress in Systemic Lupus Erythematosus Patients with Nephritis

    Lu Liu, Karina de Leeuw, Suzanne Arends, Berber Doornbos-van der Meer, Harry van Goor and Johanna Westra, University Medical Center Groningen, Groningen, Netherlands

    Background/Purpose: Lupus nephritis (LN) is regarded as one of the most severe manifestations of systemic lupus erythematosus (SLE). This inflammation in the kidneys may lead…
  • Abstract Number: 2034 • ACR Convergence 2023

    Assessment of the Immediate and Short-term Impact of an Information Course on Patients’ Knowledge About Rheumatoid Arthritis: Evaluation Using a Self-prepared and Validated Assessment Questionnaire

    Ranjan Gupta1, Rudra Prosad Goswami2, Manshi Yadav1, Sandhya Saini1, Anju Mohan1 and Vanamail Perumal1, 1All India Institute of Medical Sciences, New Delhi, India, 2Department of Rheumatology, All India Institute of Medical Sciences, New Delhi, India

    Background/Purpose: Long-term outcomes in rheumatic diseases can be improved by improving patients' knowledge, beliefs and perception about their disease which can help them in coping…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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