ACR Meeting Abstracts

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Abstracts tagged "longitudinal studies"

  • Abstract Number: 1271 • ACR Convergence 2024

    Linkage of the Childhood Arthritis and Rheumatology Research Alliance Registry with the Pediatric Health Information System: Creation of a Comprehensive Childhood-Onset Lupus Dataset

    Jordan Roberts1, Anna Faino2, Min-Lee Chang3, Jonathan Cogen4, Matt Hall5 and Esi Morgan1, and for the CARRA Registry Investigators, 1Seattle Children's Hospital, Seattle, WA, 2Seattle Children's Research Institute, Core for Biostatistics, Epidemiology and Analytics in Research, Seattle, 3Computational Health Informatics Program, Boston Children’s Hospital, Boston, MA, 4Seattle Children’s Hospital, Seattle, WA, 5Children’s Hospital Association, Lenexa, KS

    Background/Purpose: Currently, no comprehensive national multipayer dataset with inpatient and outpatient data exists for childhood rheumatologic diseases, limiting the ability to study outcomes longitudinally and…
  • Abstract Number: 2275 • ACR Convergence 2024

    Cardiovascular and Cancer Safety of JAKi Compared to TNFi in Patients with Rheumatoid Arthritis: Results from a National Registry of Advanced Therapies

    Lucia Otero-Varela1, Carlos Sanchez-Piedra2, Elena Rabadán Rubio3, Juan Camilo Sarmiento-Monroy4, Chamaida Plasencia-Rodríguez5, Diana Sueiro6, Olga Martinez7, Noemí Busquets Pérez8, Mercedes Freire González9, Fernando Sánchez-Alonso10, José María Álvaro-Gracia11 and Isabel Castrejon12, and BIOBADASER group, 1Spanish Society of Rheumatology, Madrid, Spain, 2Agencia de Evaluación de Tecnologías Sanitarias, Instituto de Salud Carlos III, Madrid, Spain, 3Hospital Universitario Principe de Asturias, Alcalá de Henares, Madrid, Spain, 4Hospital Clínic Barcelona, Barcelona, Spain, 5Hospital Universitario La Paz, MADRID, Spain, 6Complexo Hospitalario Universitario de Ourense, Ourense, Spain, 7Hospital Universitario de Salamanca, Zamora, Spain, 8HOSP. GENERAL DE GRANOLLERS, GRANOLLERS, Spain, 9Complexo Hospitalario Universitario de A Coruña, La coruna, Galicia, Spain, 10Sociedad Española de Reumatología, Madrid, Spain, 11Hospital Gregorio Marañón, Madrid, Spain, 12Hospital General Universitario Gregorio Marañon, Madrid, Spain

    Background/Purpose: Preliminary results from the ORAL Surveillance clinical trial showed an increase in the risk of major adverse cardiovascular events (MACE) and malignancies in patients…
  • Abstract Number: 1312 • ACR Convergence 2024

    Long Term Proficiency and Clinical Outcomes of a Novel Fellow’s Injection Clinic

    Rubia Ahmed1, Whitney Martin2, Sharon Banks3, Nancy Olsen4, Vincent Aluquin1 and shirley albano-aluquin1, 1Penn State Hershey College of Medicine, Hershey, PA, 2Lexington Rheumatology, West Columbia, SC, 3Penn State Health, Hershey, PA, 4Penn State University/Milton S Hershey, Hershey, PA

    Background/Purpose: Rheumatology fellows are required to learn joint and periarticular procedures during their training but achieving the necessary expertise can be challenging if the rotations…
  • Abstract Number: 2379 • ACR Convergence 2024

    Causal Proteomics-Assisted Machine Learning Model Enhances Flare Risk Prediction in Systemic Lupus Erythematosus

    Liying Chen1, Ou Deng2, Ruichen Cong2, Dingqi Lu3, Ting Fang1, Mei Chen1, Runrun Zhang4 and Xinchang Wang3, 1Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China (People's Republic), 2Graduate School of Human Sciences, Waseda University, Mikajima, Japan, 3Department of Rheumatology, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China (People's Republic), 4The Second Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China (People's Republic)

    Background/Purpose: Objectives: Systemic lupus erythematosus (SLE) is an autoimmune disease marked by unpredictable flares. However, no flare risk prediction model has been developed for Asian…
  • Abstract Number: 1326 • ACR Convergence 2024

    Which Biomarkers Indicate Imminent Progression to Inflammatory Arthritis in High Risk CCP Positive Persons?

    Laurence Duquenne1, Didem Sahin Eroglu2, Jianhua Wu3, Kate Harnden1, Andrea Di Matteo4, Lucy Elizabeth Thornton5, Rahaymin Chowdhury5, Leticia Garcia-Montoya1, Kulveer Mankia6 and Paul Emery6, 11. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, United Kingdom, 21. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Ankara, Turkey, 31. University of Leeds, Leeds Institute for Data Analytics, Leeds, United Kingdom 2.Wolfson Institute of Population Health/Queen Mary University of London, UK, Leeds, 41. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Jesi, Italy, 51. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, 2. NIHR Leeds Biomedical Research Centre, United Kingdom, Leeds, 6University of Leeds, Leeds, United Kingdom

    Background/Purpose: A risk stratification model proposed a simple score using 4 biomarkers to identify those at high risk of developing inflammatory arthritis (IA) in primary…
  • Abstract Number: 2390 • ACR Convergence 2024

    Anti-Sm Antibody Titers Vary During SLE Disease Course

    Faye Megaris1, Emily Wu2 and Kyriakos Kirou3, 1CUNY School of Medicine, Astoria, NY, 2Hospital for Special Surgery, Rochester, NY, 3Hospital for Special Surgery, New York, NY

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is characterized by positive antibodies to dsDNA and/or Sm which have high specificity for the disease. While anti-dsDNA titers are…
  • Abstract Number: 1368 • ACR Convergence 2024

    Do CsDMARDs Still Play a Significant Role in Managing Rheumatoid Arthritis in the Current Biologic/JAKI Era? A Prospective Observational Study to Estimate the Extent of Response to Conventional Synthetic DMARDs in RA– Experience from a Tertiary Care Center in South India

    Prabhu Vasanth1, John Mathew2 and Divya K3, 1Christian Medical college , Vellore , India, Vellore, Tamil Nadu, India, 2Christian Medical college , Vellore , India, Vellore, India, 3Christian Medical College, Vellore, Tamil Nadu, India

    Background/Purpose: Conventional synthetic DMARDs remained the mainstay of treatment of RA for decades. However, their use has decreased recently due to the emergence of biological…
  • Abstract Number: 2455 • ACR Convergence 2024

    Improvement Across Multi-organ Domains and Patient Reported Outcomes in Refractory Juvenile-Onset Systemic Sclerosis (jSSc) up to 4 Years After Autologous Stem Cell Transplantation (ASCT)

    Jonathan Li1, Paulina Horvei2, Franziksa Rosser3, Kirsten Rose-Felker4, Vibha Sood5, Adam Olson6, Vickie Vandergrift7, Nicole Hogue2, Lauren Farver8, Devin Mcguire9, Haley Havrilla7, Jessie Alexander10, Shawna McIntyre2, Paul Szabolcs2 and Kathryn Torok11, 1Division of Rheumatology, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, 2Division of Blood and Marrow Transplantation and Cellular Therapies, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 3Division of Pulmonology Medicine, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, 4Division of Cardiology, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 5Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 6Department of Radiation Oncology, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 7Division of Rheumatology, Scleroderma Center, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 8Department of Physical Therapy, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 9Pediatric Behavioral Health, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, 10Pediatric Bone Marrow Transplant and Cellular Therapies, Stanford Children's Hospital, Palo Alto, CA, USA, Pittsburgh, 11Division of Rheumatology, Scleroderma Center, Department of Pediatrics, UPMC Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA

    Background/Purpose: Juvenile-onset systemic sclerosis (jSSc) is a systemic autoimmune disease characterized by vasculopathy and multiorgan fibrosis leading to significant morbidity and early mortality.  Autologous stem…
  • Abstract Number: 1408 • ACR Convergence 2024

    Color Doppler Ultrasound Is a Reliable Method for Imaging the Lacrimal Glands in Patients with Suspected Sjögren’s Disease

    Ting Yang1, Neils Sluijpers1, Jolien van Nimwegen1, Alja Stel1, Adriaan Coumou1, Frans Kroese2, Hendrika Bootsma3, Konstantina Delli1 and Sarah Pringle2, 1UMCG, Groningen, Netherlands, 2University Medical Center Groningen, Groningen, Netherlands, 3Department of Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Groningen, Netherlands

    Background/Purpose: As a widely available, non-invasive and repeatable technique, ultrasound has already been used for the examination of irregularities of the major salivary glands. However,…
  • Abstract Number: 2490 • ACR Convergence 2024

    Longitudinal Kidney Function Trajectories in Patients Enrolled in the Plasma Exchange and Glucocorticoids in ANCA-Associated Vasculitis Trial

    Jennifer Hanberg1, Yuqing Zhang2, Andreas Kronbichler3, Anna Matyjek4, Carol McAlear5, Balazs Odler6, Lisa Uchida7, Duvuru Geetha8, Carmel Hawley9, David Jayne7, Michael walsh10, Peter Merkel5 and Zachary Wallace11, and the PEXIVAS investigators, 1Brigham and Women's Hospital, Boston, MA, 2Division of Rheumatology, Allergy, and Immunology, Department of Medicine, Massachusetts General Hospital, Harvard Medical School; The Mongan Institute, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 3Medical University Innsbruck and University of Cambridge, Innsbruck, Austria, 4Medical University of Lodz and Medical University Innsbruck, Lodz, Poland, 5University of Pennsylvania, Philadelphia, PA, 6Medical University of Graz, Graz, Austria, 7University of Cambridge, Cambridge, United Kingdom, 8Johns Hopkins University, Baltimore, MD, 9Princess Alexandra Hospital and Translational Research Institute, Brisbane, Australia, 10McMaster University, Hamilton, ON, Canada, 11Massachusetts General Hospital, Newton, MA

    Background/Purpose: ANCA-associated vasculitis (AAV) causes kidney damage, leading to a spectrum of chronic kidney disease (CKD) and end-stage kidney disease (ESKD). Clinically distinct kidney function…
  • Abstract Number: 1412 • ACR Convergence 2024

    Survival and Predictive Markers of Prognosis in Patients with Cancer Occurrence After Sjögren Syndrome: A Long-term Observational Study

    Yezi Peng1, Jiana Chen2, Yafei Ren3, Dan Yang2, Xiangyi Shen4, Xu Jiang5 and Huaxia Yang2, 1Department of Rheumatology and Clinical Immunology, National Clinical Research Center for Dermatologic and Immunologic Diseases, the Ministry of Education Key Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Dong Cheng Qu, Beijing, China (People's Republic), 2Department of Rheumatology and Clinical Immunology, National Clinical Research Center for Dermatologic and Immunologic Diseases, the Ministry of Education Key Laboratory, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China, 3Department of Rheumatology and immunotogy,Affiliated Hospital of Guilin Medical University,Guilin, China, Guangxi, China (People's Republic), 4Tsinghua University, Beijing, China, 5National Infrastructure for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

    Background/Purpose: Patients with Sjögren syndrome (SS) have been reported to have a higher risk of cancer than the general population, and malignancy constitutes one of…
  • Abstract Number: 2509 • ACR Convergence 2024

    Bone Marrow Failure in VEXAS Is Associated with the Degree of UBA1b Deficiency

    Benjamin Turturice1, Alice Fike1, Bhavisha Patel2, Emma Groarke2, Karyssa Stonick1, Shanni Liu1, Wendy Goodspeed1, Kaitlin Quinn1, Neal Young2 and Peter Grayson3, 1National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Bethesda, MD, 2National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, 3National Institutes of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), National Institutes of Health (NIH), Chevy Chase, MD

    Background/Purpose: VEXAS is a multisystem autoinflammatory disorder due to somatic mutations in UBA1. The disease is characterized by ineffective hematopoiesis with increased risk of transfusion…
  • Abstract Number: 1494 • ACR Convergence 2024

    Trajectories of Disease Evolution upon Treatment Initiation in Systemic Lupus Erythematosus: Pooled Results from Three Randomized Clinical Trials of Belimumab

    Ioannis Parodis1, Julius Lindblom2, Alexandre Tsoi3, Dionysis Nikolopoulos4 and Lorenzo Beretta5, 1Karolinska Institutet, Karolinska University Hospital; Örebro University, Solna, Sweden, 2Karolinska Institutet, Stockholm, Sweden, 3Karolinska Institute, Stockholm, Sweden, 4Karolinska Institutet and Karolinska University Hospital, Division of Rheumatology, Department of Medicine Solna, Stockholm, Sweden, 5Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di MIlano, Milan, Milan, Italy

    Background/Purpose: The efficacy of belimumab in treating SLE has been demonstrated in several phase 3 randomized clinical trials (RCTs). These trials showed belimumab efficacy on…
  • Abstract Number: 2555 • ACR Convergence 2024

    Addressing Economic Insecurities Could Improve Patient-Reported Outcomes in Lupus

    Shivani Garg1, Jay Patel1, Meredith Ingersoll2, Shelby Gomez2, Amanda Weber2, Sarah Panzer1, Sancia Ferguson3, Tripti Singh1 and Christie Bartels4, 1University of Wisconsin, School of Medicine and Public Health, Madison, Madison, WI, 2UW Health, Madison, 3University of Wisconsin, Madison, Madison, WI, 4University of Wisconsin School of Medicine and Public Health, Madison, WI

    Background/Purpose: A complex interaction between biologic factors and social determinants of health (SDoH) drives disparities in lupus (or SLE) outcomes in the US. A recent…
  • Abstract Number: 1539 • ACR Convergence 2024

    Effectiveness & Safety of Early versus Late Use of Rituximab in Extra-renal Lupus: Real World Experience from a Tertiary Care Centre

    JOHN KUMAR DAS1, ABHILASHA ARVIND MANWATKAR2 and JOHN MATHEW2, 1Christian Medical College, Vellore, India, 2christian medical college, vellore, Tamil Nadu, India

    Background/Purpose: Rituximab, a monoclonal antibody targeting CD20 positive B cells failed to show effectiveness in SLE, including EXPLORER and LUNAR trials.However, real world data in…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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