Abstracts tagged "Knee"

Abstract Number: 1788 • 2017 ACR/ARHP Annual Meeting
Dose Intra-Articular Injection of Corticosteroids Increase the Risk of Knee Osteoarthritis Progression? Data from the Osteoarthritis Initiative
Guang-hua Lei¹, Chao Zeng¹, Jie Wei^2,3, Yi-lun Wang¹ and Dong-xing Xie¹, ¹Department of orthopaedics, Xiangya Hospital, Central South University, Changsha, China, ²Health Management Center, Xiangya Hospital, Central South University, Changsha, China, ³Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha, China
Background/Purpose: Although intra-articular injection of corticosteroids (IAIC) has been one of the modalities of treatment for symptomatic knee OA, the recommendations for its use are…
Abstract Number: 2793 • 2017 ACR/ARHP Annual Meeting
Joint Location-Specific JAK-STAT Signaling in Rheumatoid Arthritis (RA) Fibroblast-like Synoviocytes (FLS)
Deepa Hammaker¹, Gyrid Nygaard¹, David L. Boyle², Rizi Ai³, Wei Wang⁴ and Gary S. Firestein⁵, ¹Medicine, UC San Diego, La Jolla, CA, ²University of California San Diego, La Jolla, CA, ³UC San Diego, La Jolla, CA, ⁴Chemistry and Biochemistry, UC San Diego, La Jolla, CA, ⁵Medicine, University of California San Diego, La Jolla, CA
Background/Purpose: Aberrant epigenetic marks in RA FLS contribute to disease pathogenesis and aggressive FLS behavior. Computational data also suggest that RA FLS isolated from different…
Abstract Number: 1006 • 2017 ACR/ARHP Annual Meeting
Sex Differences in Depressive Symptom Subtypes in Knee Osteoarthritis
Alan Rathbun¹, Megan Schuler², Elizabeth Stuart³, Michelle Shardell⁴, Michelle S. Yau⁵ and Marc Hochberg⁶, ¹Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, ²Rand Coportation, Boston, MA, ³Mental Health, Biostatistics, and Health Policy and Management, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁴Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, ⁵Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, ⁶Department of Medicine, University of Maryland School of Medicine, Baltimore, MD
Background/Purpose: Knee osteoarthritis (OA) is characterized by structural changes in subchondral bone and degradation of articular cartilage, but the pathology does not necessarily lead to…
Abstract Number: 1853 • 2017 ACR/ARHP Annual Meeting
Exercise and Adherence over Two Years: Beliefs of Adults with Knee Osteoarthritis
Aileen Ledingham¹, Ellen Cohn², Kristin Baker³ and Julie Keysor¹, ¹Physical Therapy, Boston University, Boston, MA, ²Occupational Therapy, Boston University, Boston, MA, ³Physical Therapy, Boston University Sargent College, Boston, MA
Background/Purpose: Exercise is an established treatment to improve pain and physical function in adults with knee osteoarthritis (KOA), which is a leading cause of disability…
Abstract Number: 2823 • 2017 ACR/ARHP Annual Meeting
Preliminary Comparison of Patient-Centered Weight Loss Programs Starting before Versus after Knee Replacement
Christine Pellegrini^1,2, Rowland W. Chang³, Dorothy D. Dunlop⁴, David Conroy^1,5, Julia (Jungwha) Lee⁶, Linda VanHorn⁶, Bonnie Spring¹ and Kenzie Cameron⁷, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Exercise Science, University of South Carolina's Arnold School of Public Health, Columbia, SC, ³Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Kinesiology, The Pennsylvania State University, University Park, PA, ⁶Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL
Background/Purpose: Most patients risk gaining weight in the years after knee replacement, adding further concern to a population that is mostly overweight/obese prior to surgery.…
Abstract Number: 1029 • 2017 ACR/ARHP Annual Meeting
What to Measure after Arthroplasty? Confirmation of a Core Domain Set
Anh Hoang¹, Susan M. Goodman², Mark P. Figgie³, Mathias Bostrom⁴, Douglas Padgett⁴, Lisa A. Mandl^5,6,7, Peter Sculco⁸, Alexander McLawhorn⁹ and Jasvinder A. Singh¹⁰, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Medicine, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ³Orthopaedic Surgery, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁴Orthopaedic Surgery, Hospital for Special Surgery, New York, NY, ⁵Department of Medicine, Hospital for Special Surgery, New York, NY, ⁶Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ⁷Department of Rheumatology, Hospital for Special Surgery, New York, NY, ⁸Orthopaedic Surgery, Hospital for Special Surgey, New York, NY, ⁹Hospital for Special Surgey, New York, NY, ¹⁰Rheumatology, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The Outcomes Measures in Rheumatology Trials (OMERACT) TJR Working Group has proposed six core domains that would constitute a standardized measurement set that can…
Abstract Number: 2019 • 2017 ACR/ARHP Annual Meeting
Structural Abnormalities in the Knee Detected By MRI in Middle-Aged Subjects without Radiographic Knee Osteoarthritis
Jaanika Kumm¹, Aleksandra Turkiewicz², Fan Zhang² and Martin Englund², ¹Department of Radiology, University of Tartu, Tartu, Estonia, ²Clinical Sciences Lund, Orthopedics, Clinical Epidemiology Unit, Lund University, Lund, Sweden
Background/Purpose: Early OA is a complex, poorly understood and still largely an unchartered “entity”. Thus, our purpose was evaluate the prevalence of findings suggestive of…
Abstract Number: 2835 • 2017 ACR/ARHP Annual Meeting
5-Year Evolution Patterns of Physical Activity and Sedentary Behavior of Patients with Symptomatic Hip and/or Knee Osteoarthritis, and Their Sociodemographic and Clinical Correlates
Sarah Bitar¹, Abdou Y Omourou^2,3, Aurélie Van-hoye¹, Francis Guillemin^4,5 and Anne-Christine Rat^4,5,6, ¹Université de Lorraine, EA 4360 APEMAC, Nancy, France, ²Université de lorraine, EA 4360 APEMAC, Nancy, France, ³Inserm, CIC-1433 Clinical epidemiology, Nancy, France, ⁴Université de Lorraine, EA4360, APEMAC, Nancy, France, ⁵Inserm, CIC-1433 Epidémiologie Clinique, Vandoeuvre-lès-Nancy, France, ⁶Rheumatology Department, CHRU Nancy, Vandoeuvre-lès-Nancy, France
Background/Purpose: Regular Physical Activity (PA) at a moderate level of intensity for approximately 2.5 hours per week is recommended in the management of hip and/or…
Abstract Number: 1043 • 2017 ACR/ARHP Annual Meeting
Comparison of the Costs for Hyaluronic Acid and Total Knee Arthroplasty in the Treatment of OA for the Blue Cross/Blue Shield Patient Population
Kevin Ong¹, Faizan Niazi², Edmund Lau³, Peter Shaw² and Steven Kurtz¹, ¹Exponent, Inc., Philadelphia, PA, ²Ferring Pharmaceuticals, Inc., Parsippany, NJ, ³Exponent, Inc., Menlo Park, CA
Background/Purpose: Previous HA studies have focused on the Medicare population, but less is known of the treatment patterns and cost of HA relative to knee…
Abstract Number: 2178 • 2017 ACR/ARHP Annual Meeting
Metabolic Osteoarthritis: Relation of Cardiovascular Disease and Diabetes to Knee Osteoarthritis
Laura Kuusalo¹, David T. Felson², Carrie Brown³, Cora E. Lewis⁴, James Torner⁵ and Tuhina Neogi², ¹University of Turku and Turku University Hospital, Turku, Finland, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Boston University School of Public Health, Boston, MA, ⁴University of Alabama Birmingham, Birmingham, AL, ⁵University of Iowa, Iowa City, IA
Background/Purpose: Metabolic changes or low-grade inflammation related to cardiovascular disease (CVD) and diabetes have been hypothesized to contribute to the development of OA. Prior studies…
Abstract Number: 2852 • 2017 ACR/ARHP Annual Meeting
Widespread Pain Prior to Total Knee Replacement (TKR) Is Associated with Increased Risk of No Clinical Improvement in Pain Among Women
Ernest Vina¹, Di Ran², Erin L. Ashbeck² and C. Kent Kwoh³, ¹Rheumatology, University of Arizona, Tucson, AZ, ²The University of Arizona Arthritis Center, Tucson, AZ, ³University of Arizona, Tucson, AZ
Background/Purpose: Up to 47% of individuals may not have clinically significant improvement following joint replacement surgery. Evidence also suggests that women are less likely to…
Abstract Number: 1050 • 2017 ACR/ARHP Annual Meeting
Prevalence and Predictors of Knee Replacement Overuse and Underuse in the US
Hassan Ghomrawi¹, Alvin Mushlin², Raymond Kang³, Samprit Banerjee², Jasvinder A. Singh⁴, Leena Sharma⁵, Tuhina Neogi⁶, Michael C. Nevitt⁷ and Daniel Riddle⁸, ¹Surgery and Pediatrics/Center for Healthcare Studies, Feinberg School of Medicine of Northwestern University, Chicago, IL, ²Healthcare Policy and Research, Weill Cornell Medical College, New York, NY, ³Center for Healthcare Studies, Feinberg School of Medicine of Northwestern University, Chicago, IL, ⁴Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ⁵Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁷Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁸Virginia Commonwealth University, Richmond, VA
Background/Purpose: The elective nature of knee replacement (KR) creates difficult decisions and the potential for both overuse and underuse. We examined the temporal relationship between…
Abstract Number: 2183 • 2017 ACR/ARHP Annual Meeting
Two-Year Changes in Knee Osteoarthritis Symptoms: Comparing Clinical Relevance of Patient-Reported Outcomes By Anchoring to Knee Replacement
C. Kent Kwoh¹, Hans Guehring², Erin Ashbeck³, Michael J Hannon⁴ and Aida Aydemir⁵, ¹University of Arizona Arthritis Center, Tuscan, AZ, ²Merck KGaA, Darmstadt, Germany, ³The University of Arizona Arthritis Center, Tucson, AZ, ⁴Medicine, University of Pittsburgh, Pittsburgh, PA, ⁵EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA
Background/Purpose: Randomized controlled trials (RCTs) of interventions for knee OA (KOA) may include a patient-reported outcome (PRO) measure as a primary endpoint. Several measures of…
Abstract Number: 2948 • 2017 ACR/ARHP Annual Meeting
Distinct Trajectories of Medial Fixed Joint Space Width Loss over Four Years of Follow-up Among Knees with and at Risk for Knee Osteoarthritis
C. Kent Kwoh^1,2, Di Ran^2,3, Erin L. Ashbeck² and Jeffrey Duryea⁴, ¹Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, ²The University of Arizona Arthritis Center, Tucson, AZ, ³Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, Tucson, AZ, ⁴Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA
Background/Purpose: Knee OA (KOA) is typically described as a slowly progressive disease, though it is recognized that some patients experience rapid structural deterioration. Identification of…
Abstract Number: 1059 • 2017 ACR/ARHP Annual Meeting
Cost-Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis
John B. Wong¹, Mei Chung², Lori Lyn Price³ and Chenchen Wang^4,5, ¹Tufts Medical Center, Boston, MA, ²Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, ³Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁴Rheumatology, Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA, ⁵Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: A single-blind randomized comparative effectiveness trial showed that Tai Chi yielded beneficial effects similar to those of a standard course of physical therapy in…

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