Abstracts tagged "Knee"

Abstract Number: 2183 • 2017 ACR/ARHP Annual Meeting
Two-Year Changes in Knee Osteoarthritis Symptoms: Comparing Clinical Relevance of Patient-Reported Outcomes By Anchoring to Knee Replacement
C. Kent Kwoh¹, Hans Guehring², Erin Ashbeck³, Michael J Hannon⁴ and Aida Aydemir⁵, ¹University of Arizona Arthritis Center, Tuscan, AZ, ²Merck KGaA, Darmstadt, Germany, ³The University of Arizona Arthritis Center, Tucson, AZ, ⁴Medicine, University of Pittsburgh, Pittsburgh, PA, ⁵EMD Serono Research & Development Institute, Inc. (a business of Merck KGaA, Darmstadt, Germany), Billerica, MA
Background/Purpose: Randomized controlled trials (RCTs) of interventions for knee OA (KOA) may include a patient-reported outcome (PRO) measure as a primary endpoint. Several measures of…
Abstract Number: 2948 • 2017 ACR/ARHP Annual Meeting
Distinct Trajectories of Medial Fixed Joint Space Width Loss over Four Years of Follow-up Among Knees with and at Risk for Knee Osteoarthritis
C. Kent Kwoh^1,2, Di Ran^2,3, Erin L. Ashbeck² and Jeffrey Duryea⁴, ¹Division of Rheumatology, Department of Medicine, The University of Arizona, Tucson, AZ, ²The University of Arizona Arthritis Center, Tucson, AZ, ³Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, Tucson, AZ, ⁴Radiology, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA
Background/Purpose: Knee OA (KOA) is typically described as a slowly progressive disease, though it is recognized that some patients experience rapid structural deterioration. Identification of…
Abstract Number: 1059 • 2017 ACR/ARHP Annual Meeting
Cost-Effectiveness of Tai Chi Versus Physical Therapy for Knee Osteoarthritis
John B. Wong¹, Mei Chung², Lori Lyn Price³ and Chenchen Wang^4,5, ¹Tufts Medical Center, Boston, MA, ²Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, ³Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, ⁴Rheumatology, Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA, ⁵Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: A single-blind randomized comparative effectiveness trial showed that Tai Chi yielded beneficial effects similar to those of a standard course of physical therapy in…
Abstract Number: 2185 • 2017 ACR/ARHP Annual Meeting
Relation of Foot Pronation to Medial Knee Load in Persons with Medial Knee Osteoarthritis
K. Douglas Gross¹, Richard Jones², David T. Felson³, Salinda Chong⁴ and Howard J. Hillstrom⁵, ¹Physical Therapy, MGH Institute of Health Professions, Boston, MA, ²School of Health Sciences, University of Salford, Manchester, United Kingdom, ³Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ⁴MGH Institute of Health Professions, Boston, MA, ⁵Rehabilitation, Hospital Special Surgery (HSS), New York, NY
Background/Purpose: The knee adduction moment (KAM) estimates medial knee load during gait, with high KAM fueling worsening OA. Understanding how foot mechanics contribute to KAM…
Abstract Number: 1192 • 2017 ACR/ARHP Annual Meeting
Patient Characteristics That Predict the Effect of Laparoscopic Adjustable Gastric Band Weight Loss Surgery on Knee Osteoarthritis Pain
Shannon Chen¹, Fernando Bomfim², Heekoung Youn³, Christine Ren-Fielding⁴ and Jonathan Samuels⁵, ¹Medicine, NYU Langone Medical Center, New York, NY, ²NYU Langone Medical Center, New York, NY, ³Surgery, NYU Langone Medical Center, New York, NY, ⁴Department of Surgery, New York University School of Medicine, New York, NY, ⁵Department of Medicine, NYU School of Medicine, NYU Langone Medical Center, New York, NY
Background/Purpose: Obesity is a modifiable risk factor for knee osteoarthritis (OA), yet diet and exercise often fail to achieve sustained weight loss or knee improvement.…
Abstract Number: 2189 • 2017 ACR/ARHP Annual Meeting
Metabolic Syndrome Influences the Radiographic Progression of Knee Osteoarthritis and Condition the Risk of Erosive Hand OA
Natividad Oreiro¹, Mercedes Fernandez Moreno², Estefanía Cortés-Pereira², Maria Eugenia Vazquez Mosquera³, Sonia Pertega⁴, Sara Relaño-Fernandez⁵, Ana Cecilia Raga⁶, Carlos Fernandez-Lopez⁶, Ignacio Rego-Pérez⁶ and Francisco J Blanco⁶, ¹Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruna, Spain, ²Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruna, Spain, ³Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, ⁴Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, ⁵Plataforma de Genómica. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña, España, A Coruña, Spain, ⁶Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruña, Spain
Background/Purpose: The contribution of metabolic factors in the development of OA has not been fully elucidated. The aim of this work is to analyze the…
Abstract Number: 1194 • 2017 ACR/ARHP Annual Meeting
Are Bisphosphonates Efficacious in Knee Osteoarthritis? A Meta-Analysis of Randomized Controlled Trials
Mikala C. Osani¹, Elizaveta Vaysbrot¹, Raveendhara R. Bannuru², Mia-Cara Musetti¹ and Timothy E. McAlindon¹, ¹Division of Rheumatology, Tufts Medical Center, Boston, MA, ²Center of Integrative Medicine and Division of Rheumatology, Tufts Medical Center, Boston, MA, Boston, MA
Background/Purpose: One of the key aspects of osteoarthritis (OA) pathogenesis is subchondral bone remodeling. Bisphosphonates have been touted as disease-modifying agents for OA due to…
Abstract Number: 2192 • 2017 ACR/ARHP Annual Meeting
Association between Mitochondrial DNA (mtDNA) Haplogroups and Bone Marrow Lesions at 24 Months in Osteoarthritis Subjects: Subjets from the Osteoarthritis Initiative
Ignacio Rego-Pérez¹, Jean-Pierre Pelletier², François Abram³, Natividad Oreiro⁴, Carlos Fernandez-Lopez¹, Ana Cecilia Raga¹, Francisco J Blanco¹ and Johanne Martel-Pelletier², ¹Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruña, Spain, ²Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Montreal, QC, Canada, ³Medical Imaging Research & Development, ArthroLab Inc., Montreal, QC, Canada, ⁴Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC). As Xubias, 15006. A Coruña. España, A Coruna, Spain
Background/Purpose: Bone marrow lesions (BMLs) have been consistently associated with the development of osteoarthritis (OA); however the extent to which they are genetically driven by…
Abstract Number: 1198 • 2017 ACR/ARHP Annual Meeting
Intra-Articular Hyaluronic Acid Delay to Total Knee Arthroplasty By Number of Injection Courses Received: Analysis of an Administrative Database
Andrew Concoff¹, Faizan Niazi², Peter Shaw² and Jeffrey Rosen³, ¹Rheumatology, St. Jude Medical Center, Fullerton, CA, ²Ferring Pharmaceuticals Inc., Parsippany, NJ, ³Department of Orthopaedics & Rehabilitation, New York Presbyterian Queens; Department of Clinical Orthopaedic Surgery, Weill Medical College of Cornell University, New York, NY, New York, NY
Background/Purpose: Total knee arthroplasty (TKA) is the standard surgical treatment for patients with osteoarthritis (OA) that no longer experience symptom relief from conservative or pharmacologic…
Abstract Number: 2193 • 2017 ACR/ARHP Annual Meeting
Physical Activity and Disease Progression in Persons with or at Higher Risk for Knee Osteoarthritis
Prakash Jayabalan^1,2, Gerald W. Rouleau¹, Masha Kocherginsky¹, Dorothy D. Dunlop¹, Julia (Jungwha) Lee¹, Rowland W. Chang¹ and Leena Sharma¹, ¹Northwestern University, Chicago, IL, ²Shirley Ryan AbilityLab, Chicago, IL
Background/Purpose: The benefits of physical activity in the general population and among persons with knee osteoarthritis (OA) are well-established. However, it remains unclear if inactivity…
Abstract Number: 312 • 2017 ACR/ARHP Annual Meeting
Rates of Total Joint Replacement Utilization in the U.S.: Future Projections to 2020-2040 Using the National Inpatient Sample
Jasvinder A. Singh and Shaohua Yu, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: To project the future utilization of total hip and knee joint arthroplasty (THA, TKA).Methods: We used the 2000-2010 U.S. National Inpatient Sample combined with…
Abstract Number: 1199 • 2017 ACR/ARHP Annual Meeting
Costs Associated with Osteoarthritis Care Using Intra-Articular Hyaluronic Acid: Analysis of an Administrative Database
Andrew Concoff¹, Faizan Niazi², Peter Shaw² and Jeffrey Rosen³, ¹Rheumatology, St. Jude Medical Center, Fullerton, CA, ²Ferring Pharmaceuticals Inc., Parsippany, NJ, ³Department of Orthopaedics & Rehabilitation, New York Presbyterian Queens; Department of Clinical Orthopaedic Surgery, Weill Medical College of Cornell University, New York, NY, New York, NY
Background/Purpose: Many treatment options are available for the management of knee osteoarthritis (OA). The need for non-operative management is motivated by the large costs associated…
Abstract Number: 2197 • 2017 ACR/ARHP Annual Meeting
Systemic Inflammation and Physical Function in Knee Osteoarthritis
Devyani Misra¹, Carrie Brown², Roger A. Fielding³, Tuhina Neogi⁴, Michael C. Nevitt⁵, Cora E. Lewis⁶, James Torner⁷ and David T. Felson⁴, ¹Medicine, Section of, Boston University School of Medicine, Boston, MA, ²Boston University School of Public Health, Boston, MA, ³Nutrition, Exercise Physiology and Sarcopenia Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA, ⁴Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁵Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁶University of Alabama Birmingham, Birmingham, AL, ⁷University of Iowa, Iowa City, IA
Background/Purpose: Knee osteoarthritis (OA) is a leading cause of functional limitation and disability in older adults. But why some knee OA patients develop functional limitation…
Abstract Number: 926 • 2017 ACR/ARHP Annual Meeting
Relationship of Traumatic Knee Injuries to Early-Onset Knee Osteoarthritis in Young Military Officers
Yvonne M. Golightly¹, Maryalice Nocera², John Cantrell², Jordan B. Renner³ and Stephen W. Marshall⁴, ¹Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²Injury Prevention Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ³UNC School of Medicine, University of North Carolina, Chapel Hill, NC, ⁴Epidemiology, University of North Carolina, Chapel Hill, NC
Background/Purpose: Traumatic knee injuries, such as tears and ruptures of the anterior cruciate ligament (ACL) and/or menisci, are associated with osteoarthritis (OA). Surprisingly little is…
Abstract Number: 1200 • 2017 ACR/ARHP Annual Meeting
Updating the Knee Osteoarthritis Intra-Articular Corticosteroid Meta-Analysis with Two Large Trials of Extended-Release Triamcinolone Acetonide (FX006) Versus Placebo
Philip G. Conaghan¹, Francis Berenbaum², Virginia B. Kraus³, James Johnson⁴ and Scott Kelley⁵, ¹Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ²Pierre & Marie Curie University, Saint-Antoine Hospital, Paris, France, ³Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, ⁴Summit Analytical, Denver, CO, ⁵Flexion Therapeutics, Inc., Burlington, MA
Background/Purpose: A recent meta-analysis concluded that intra-articular corticosteroids (IACS) for knee osteoarthritis (OA) may be associated with moderate improvement in pain compared with control treatment.1,2…

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