Abstracts tagged "Knee"

Abstract Number: 950 • 2015 ACR/ARHP Annual Meeting
In a Two-Year Double-Blind Randomized Controlled Multicenter Study, Chondroitin Sulfate Was Significantly Superior to Celecoxib at Reducing Cartilage Loss with Similar Efficacy at Reducing Disease Symptoms in Knee Osteoarthritis Patients
Jean-Pierre Pelletier¹, Jean Pierre Raynauld², André Beaulieu³, Louis Bessette⁴, Frédéric Morin⁵, Artur J Fernandes⁶, François Abram⁷, Marc Dorais⁸ and Johanne Martel-Pelletier⁹, ¹Rheumatology, Institut de recherche en rhumatologie de Montréal (IRRM), Montréal, QC, Canada, ²Osteoarthritis Research Unit, CRCHUM, Montreal, Montreal, QC, Canada, ³Centre de rhumatologie St-Louis, St. Louis, QC, Canada, ⁴Groupe de Recherche en Rhumatologie et Maladies Osseuses, Quebec, Quebec, QC, Canada, ⁵Centre de Recherche Musculo-squelettique, Trois-Rivières, Trois-Rivières, QC, Canada, ⁶Centre de Recherche Musculo-squelettique, Trois-Rivières, 6Rheumatology Division, Sherbrooke, Sherbrooke, QC, Canada, ⁷Medical Imaging Research & Development, ArthroLab Inc, Montreal, QC, Canada, ⁸StatSciences Inc., Montreal, Canada, Montreal, QC, Canada, ⁹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM),, Montreal, QC, Canada
Background/Purpose: In osteoarthritis (OA) treatment, although chondroitin sulfate (CS) was found in a number of studies using radiography to have a structure modifying effect, to…
Abstract Number: 2248 • 2015 ACR/ARHP Annual Meeting
Knee Pain Burden Is Associated with Decreased Motor Performance: Data from the Osteoarthritis Initiative
Javad Razjouyan¹, Bijan Najafi², Erin Ashbeck³, Dorothy D. Dunlop⁴, Julia (Jungwha) Lee⁵, Lynn Hamilton³ and C. Kent Kwoh⁶, ¹Consortium on Advanced Motion Performance (iCAMP), Department of Surgery, University of Arizona, Tucson, AZ, ²Department of Surgery and Department of Biomedical Engineering, University of Arizona, Tucson, AZ, ³Arthritis Center, University of Arizona, Tucson, AZ, ⁴Institute for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Department of Preventive Medicine, Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁶Rheumatology, University of Arizona, Tucson, AZ
Background/Purpose: Knee pain is the presenting symptom in knee osteoarthritis (OA), but the impact of knee pain burden in OA has been understudied. We examined…
Abstract Number: 2861 • 2014 ACR/ARHP Annual Meeting
Changes in Knee Kinematics from a 6-Week Hip and Trunk Strengthening Program for Persons with Patellofemoral Osteoarthritis
Lisa Hoglund¹, Laura Pontiggia², John Kelly IV³, Mark Arnott⁴, Olumide Babalola⁴, Andrew Gushen⁴ and James Carey³, ¹Department of Physical Therapy, University of the Sciences, Philadelphia, PA, ²Mathematics, Physics, and Statistics, University of the Sciences, Philadelphia, PA, ³Orthopaedic Surgery, University of Pennsylvania, Philadelphia, PA, ⁴Physical Therapy, University of the Sciences, Philadelphia, PA
Background/Purpose: Patellofemoral (PF) osteoarthritis (OA) is prevalent in middle-aged adults. Aberrant lower extremity (LE) biomechanics is one etiology of knee OA. Reduced peak knee flexion…
Abstract Number: 1280 • 2014 ACR/ARHP Annual Meeting
Relationship of Buckling and Knee Injury to Pain Exacerbation in Knee Osteoarthritis: A Web-Based Case-Crossover Stud
Isabelle Zobel^1,2, Tahereh Erfani³, Kim Bennell⁴, Joanna Makovey³, Ben Metcalf⁴, Jian Sheng Chen⁵, Lyn March³, Yuqing Zhang⁶, Felix Eckstein⁷ and David J. Hunter³, ¹Institute of Anatomy, Paracelsus Medical University Salzburg, Salzburg, Austria, ²Institute of Bone and Joint Research, Kolling Institute, University of Sydney, St Leonards, Australia, ³Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁴University of Melbourne, Melbourne, Australia, ⁵Rheumatology Royal North Shore Hospital, University of Sydney Institute of Bone and Joint Research, St Leonards, Australia, ⁶Boston University School of Medicine, Boston, MA, ⁷Anatomy & Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
Background/Purpose Knee osteoarthritis (OA) pain is neither constant nor stable and exacerbations of pain are disabling. We examined whether knee injury and buckling (giving way)…
Abstract Number: 213 • 2014 ACR/ARHP Annual Meeting
Foot Center of Pressure in Knee Osteoarthritis (OA) and Its Association with Knee Load Reduction with Barefoot Walking
Christopher Ferrigno¹, Roy H. Lidtke², Markus Wimmer³, Anjali Nair², Laura E. Thorp⁴, Louis F. Fogg⁵, Joel A. Block⁶ and Najia Shakoor⁶, ¹Department of Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL, ²Section of Rheumatology, Rush University Medical Center, Chicago, IL, ³Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL, ⁴Anatomy and Cell Biology, Rush University Medical Center, Chicago, IL, ⁵Department of Nursing, Rush University Medical Center, Chicago, IL, ⁶Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Biomechanical factors including excessive knee loading have been shown to be important in the pathophysiology, severity and progression of knee osteoarthritis (OA). Several biomechanical…
Abstract Number: 2437 • 2014 ACR/ARHP Annual Meeting
Why Doesn’t Participation in Activity Increase Following Hip or Knee Replacement?
Aileen Davis¹, Viji Venkataramanan¹, Jessica Bytautas², Rose Wong¹, Lisa Carlesso¹, Anthony Perruccio³ and Fiona Webster², ¹Division of Health Care & Outcomes Research, Toronto Western Research Institute, University Health Network, Toronto, ON, Canada, ²Department of Family and Community Medicine, University of Toronto, Toronto, ON, Canada, ³Toronto Western Hospital, University Health Network, Toronto, ON, Canada
Background/Purpose Activity is critical for healthy aging. Our prior work demonstrated that despite improved pain and function, people did not increase their participation in activity…
Abstract Number: 1191 • 2014 ACR/ARHP Annual Meeting
The Kimriss Bone Marrow Lesion Score in Patients with Osteoarthritis of the Knee Correlates with WOMAC Pain Status Using Target-Lesion Based Scoring Methodology; Data from the Osteoarthritis Initiative
David McDougall¹, Jacob Jaremko¹, RG Lambert¹ and Walter P. Maksymowych², ¹Radiology, University of Alberta, Edmonton, AB, Canada, ²Medicine/Rheumatic Dis Unit, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Inflammatory components of osteoarthritis including bone marrow lesions (BML) may be a target for therapy. Limited literature quantifies the relation of these markers on…
Abstract Number: 212 • 2014 ACR/ARHP Annual Meeting
Relation of Shoe Stability to Risk of Knee Cartilage Damage: The Multicenter Osteoarthritis Study
K. Douglas Gross^1,2, Howard J. Hillstrom³, Jingbo Niu⁴, Michael C. Nevitt⁵, James C. Torner⁶, Cora E. Lewis⁷ and David T. Felson², ¹Physical Therapy, MGH Institute of Health Professions, Boston, MA, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Rehabilitation, Hospital Special Surgery (HSS), New York, NY, ⁴Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, ⁵Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁶Epidemiology, University of Iowa, Iowa City, Iowa City, IA, ⁷Preventive Medicine, The University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Clinical guidelines recommend that “every patient with knee osteoarthritis should receive advice concerning appropriate footwear”, yet the recommended content of this advice is not…
Abstract Number: 2353 • 2014 ACR/ARHP Annual Meeting
The Nitric Oxide Receptor Soluble Guanylyl Cyclase Is Found in Lymphatic Vessels of Arthritic Mice and Inhibition Alters Lymphatic Pulse
Homaira Rahimi¹, Yawen Ju², Echoe M. Bouta³, Ronald Wood⁴, Christopher T. Ritchlin⁵ and Edward M. Schwarz⁶, ¹Rheumatology, University of Rochester/Golisano Children's Hospit, Rochester, NY, ²Univ of Rochester Med Ctr, University of Rochester, Rochester, NY, ³University of Rochester School of Medicine and Dentistry, Rochester, NY, ⁴Department of Urology, University of Rochester Medical Center, Rochester, NY, ⁵Allergy Immunology & Rheumatology, University of Rochester Medical Center, Rochester, NY, ⁶Center for Musculoskeletal Research, University of Rochester, Rochester, NY
Background/Purpose: Rheumatoid arthritis (RA) is a chronic erosive inflammatory condition that is characterized by episodes of “flare” due to synovitis of an affected joint. It…
Abstract Number: 1087 • 2014 ACR/ARHP Annual Meeting
The Prevalence of Knee Arthritis and Associated Self-Reported Limitation of Activity in Chinese Populations
Xu Tang Sr., Ke TAO, Qiang LIU, Xu Wu, Zheng Ming Cao and Jian Hao Lin, Arthritis Institute, People’s Hospital, Peking University, Beijing, China
Background/Purpose To estimate the prevalence of knee arthritis and assess the association between knee arthritis and self-reported limitation of activity in Chinese Populations. Methods Populations:…
Abstract Number: 195 • 2014 ACR/ARHP Annual Meeting
Dependence on Walking Aids and Patient-Reported Outcomes after Total Knee Arthroplasty
Jasvinder A. Singh¹ and David Lewallen², ¹University of Alabama and VA Medical Center, Birmingham, AL, ²Orthopedics, Mayo Clinic college of medicine, Rochester, MN
Background/Purpose: To examine whether function and pain outcomes of patients undergoing primary total knee arthroplasty (TKA) are changing over time.Methods: The Mayo Clinic Total Joint…
Abstract Number: 2231 • 2014 ACR/ARHP Annual Meeting
Combined Chondroitin Sulfate and Glucosamine Is Comparable to Celecoxib for Painful Knee Osteoarthritis. Results from a Multicenter, Randomized, Double-Blind, PHASE IV NON-Inferiority TRIAL
Marc Hochberg¹, Johanne Martel-Pelletier², Jordi Monfort³, Ingrid Moller⁴, Juan Ramon Castillo⁵, Nigel K. Arden^6,7,8, Francis Berenbaum^9,10, Jean-Pierre Pelletier¹¹, Francisco J. Blanco¹², Philip G. Conaghan¹³, Yves Henrotin^14,15, Thomas Pap¹⁶, Pascal Richette^17,18,19, Allen Sawitzke²⁰, Patrick du Souich²¹ and Moves Investigation Group²², ¹University of Maryland School of Medicine, Baltimore, MD, ²Osteoarthritis Research Unit CR-CHUM, Notre-Dame Hospital 1560 Sherbrooke St East, Montreal, QC, Canada, ³Department of Rheumatology, Grup de recerca cel•lular en inflamació i cartílag. IMIM (Institut de Recerca Hospital del Mar), Barcelona, Spain, ⁴Instituto Poal, Barcelona, Spain, ⁵Head of Clinical Pharmacology Unit Hospital Universitario Virgen del Rocío, Sevilla, Spain;, Sevilla, Spain, ⁶NIHR Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom, ⁷Arthritis Research UK (ARUK), Center for Sports, Exercise and Osteoarthritis, University of Oxford, Nuffield Orthopaedic Centre, Oxford, United Kingdom, ⁸MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, United Kingdom, ⁹Sorbonne University, INSERM UMR S938, UPMC, University of Paris 06, DHU i2B, Paris, France, ¹⁰Department of Rheumatology, Assistance Publique – Hôpitaux de Paris, Saint-Antoine Hospital, Paris, France, ¹¹Osteoarthritis Research Unit, University of Montreal Hospital Research Centre (CRCHUM), Notre-Dame Hospital, Montreal, QC, Canada, ¹²Rheumatology Service, INIBIC-Hospital Universitario A Coruña, A Coruña, Spain, ¹³University of Leeds, Leeds, United Kingdom, ¹⁴Physical Therapy and Rehabilitation Department, Princess Paola Hospital, Marche-en-Famenne, Belgium, ¹⁵Bone and Cartilage Research Unit, Arthropôle Liège, University of Liège, Institute of Pathology, CHU Sart-Tilman, Liege, Belgium, ¹⁶Institute of Experimental Muskuloskeletal Medicine University Hospital Münster, Münster, Germany, ¹⁷Université Paris Diderot, UFR médicale, Paris, France, ¹⁸INSERM 1132, Université Paris-Diderot, Hôpital Lariboisière, Paris, France, ¹⁹2 Rue Ambroise Pare, Hopital Lariboisiere, Paris, France, ²⁰Rheumatology, University of Utah Medical Center, Salt Lake City, UT, ²¹Department of Pharmacology, Faculty of Medicine, University of Montreal, Montreal, QC, Canada, ²²Spain, Germany, France and Poland, Barcelona, Spain
Background/Purpose The Multicentre Osteoarthritis interVEntion trial with Sysadoa (MOVES) compared efficacy and safety of Chondroitin sulfate (CS) and Glucosamine Hydrochloride (GH) with that of Celecoxib…
Abstract Number: 1024 • 2014 ACR/ARHP Annual Meeting
Racial Differences in Biochemical Knee Cartilage Composition Between African American and Caucasian American Women with MR-Based T2 Relaxation Time Measurements – Data from the Osteoarthritis Initiative
Martin Kretzschmar¹, Ursula Heilmeier², Aihong Yu³, Gabby B. Joseph⁴, Felix Liu⁵, Hans Liebl³, Charles E. McChulloch⁶, Michael C. Nevitt⁷, Nancy E. Lane⁸ and Thomas M Link⁹, ¹Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging,, University of California, San Francisco, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ³Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San Francisco, CA, ⁴Musculoskeletal and Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging, University of California San Francisco, San FRancisco, CA, ⁵University of California at San Francisco, San Francisco, CA, ⁶Department of Epidemiology and Biostatistics, University of California San Francisco, San Francisco, CA, ⁷Epidemiology & Biostatistics, UCSF (University of California, San Francisco), San Francisco, CA, ⁸Internal Medicine, Center for Musculoskeletal Health, UC Davis School of Medicine, Sacramento, CA, ⁹Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA
Background/Purpose: To determine whether knee cartilage composition differs between African-American and matched Caucasian-American women at risk for Osteoarthitis (OA) using in-vivo 3T MRI T2 relaxation…
Abstract Number: 66 • 2014 ACR/ARHP Annual Meeting
Association of Knee Osteoarthritis and Limitations in Physical Function in a Rural Chinese Population: The Wuchuan OA Study
Xu Wu¹, Jingbo Niu², Yan Ke³, Qiang LIU⁴, Xu Tang Sr.⁵, Zhengming Cao³, Rujun Li³, Hu Li³, Kai Wang³, Xin Zhi³, Daniel White⁶ and Jian Hao Lin⁵, ¹Peking University People's Hospital Arthritis Clinic & Research Center, Peking University Health Science Center, Beijing, China, ²Clinical Epidemiology Research and Training Unit, Boston University, Boston, MA, ³Peking University People’s Hospital, Beijing, China, ⁴Arthritis Clinical and Reserch Center, Peking University People's Hospital, Peking University Health Science Center, Beijing, China, ⁵Peking University Health Science Center, Beijing, China, ⁶Clinical Epidemiology Training, Boston Univ School of Med, Boston, MA
Background/Purpose knee osteoarthritis (OA) causes more limitations in physical function than other chronic conditions in Caucasians. Knee OA is known to be more prevalent among…
Abstract Number: 2238 • 2014 ACR/ARHP Annual Meeting
Exploratory Six Month Phase IIa Study of a Potential Disease Modifying Drug in Patients with OA of the Knee
Ketan Desai, Voltarra Pharma, Easton, PA
Background/Purpose: No disease modifying drugs exists to treat osteoarthritis. Recently, a phase II study from Tasmania showed that Zoledronic Acid, a bisphosphonate, has an effect…

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