ACR Meeting Abstracts

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Abstracts tagged "Juvenile idiopathic arthritis"

  • Abstract Number: 1626 • ACR Convergence 2021

    Use of Total Hip Arthroplasty in Patients Under 21 Years Old: A U.S. Population Analysis

    J. Alex Gibbons1, Cynthia Kahlenberg1, Deanna Jannat-Khah1, Susan Goodman1, Lisa Mandl1, Peter Sculco1, Stuart Goodman2, Mark Figgie1 and Bella Mehta3, 1Hospital for Special Surgery, New York, NY, 2Stanford University, Stanford, CA, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY

    Background/Purpose: Total hip arthroplasty (THA) is a treatment option for young patients with severe hip pathology due to congenital, developmental, rheumatologic, traumatic, and other acquired…
  • Abstract Number: 0243 • ACR Convergence 2021

    Effectiveness of Abatacept in Patients with JIA, Classified by Category: Results from the PRCSG/PRINTO JIA Real-World Registry

    Daniel Lovell1, Nikolay Tzaribachev2, Tracy Ting3, Ekaterina Alexeeva4, Teresa Giani5, Thomas Griffin6, John Bohnsack7, Andrew Zeft8, Richard Vehe9, Stacey Tarvin10, Gerd Horneff11, Maria Trachana12, Alyssa Dominique13, Lixian Dong13, Tzuyung Douglas Kou13, Robert Wong14, Alberto Martini15, Hermine Brunner3 and Nicolino Ruperto16, 1Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, 2PRI Research, Bad Bramstedt, Germany, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Scientific Center of Children Health of RAMS, Moscow, Russia, 5Università di Siena, Siena, Italy, 6Levine Children's Hospital, Charlotte, NC, 7University of Utah, Salt Lake City, UT, 8Cleveland Clinic, Cleveland, OH, 9University of Minnesota, Twin Cities, MN, 10Riley Hospital for Children at Indiana University, Indianapolis, IN, 11Paediatric Rheumatology International Trials Organisation (PRINTO), Sankt Augustin, Germany, 12Aristotle University of Thessaloniki, Thessaloniki, Greece, 13Bristol Myers Squibb, Princeton, NJ, 14Bristol Myers Squibb, Basking Ridge, NJ, 15Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, 16IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy

    Background/Purpose: Long-term treatment with abatacept, a selective T-cell co-stimulation modulator, is effective and well tolerated in patients with JIA.1–4 The objective of this analysis was…
  • Abstract Number: 0263 • ACR Convergence 2021

    Patterns of Medication Switching in Juvenile Idiopathic Arthritis: A Retrospective Analysis of a National Administrative Claims Database

    Mei-Sing Ong1, Sarah Ringold2, Melissa Mannion3, Marc Natter4, Laura Schanberg5 and Yukiko Kimura6, 1Harvard Medical School & Harvard Pilgrim Healthcare Institute, Boston, MA, 2Seattle Children's Hospital, Seattle, WA, 3University of Alabama at Birmingham, Birmingham, AL, 4Boston Children's Hospital, Boston, MA, 5Duke University Medical Center, Durham, NC, 6Hackensack University Medical Center, New York, NY

    Background/Purpose: Although the increasing availability of biologic disease-modifying antirheumatic drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs) has significantly improved outcomes for patients with Juvenile Idiopathic…
  • Abstract Number: 1631 • ACR Convergence 2021

    Predictive Factors for Lack of Response to Treatment in a Long-term Cohort of Patients with Juvenile Idiopathic Arthritis-associated Uveitis

    Francesca Minoia1, Luca Marelli2, Francesca Pregnolato3, Gisella Beatrice Beretta4, Chiara Mapelli4, Gaia Leone4, Gilberto Cincinelli3, Paolo Nucci5, Teresa Giani6, Elisabetta Miserocchi7 and Rolando Cimaz8, 1Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy, 2Ospedale San Giuseppe, IRCCS Multimedica, Milan, Italy, 3Università degli Studi di Milano, Milan, Italy, 4Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, 5Ospedale San Giuseppe, IRCCS Multimedica, Università degli Studi di Milano, Milan, Italy, 6Università di Siena, Siena, Italy, 7San Raffaele Scientific Institute, Milan, Italy, 8ASST Gaetano Pini-CTO, Università degli Studi di Milano, Milan, Italy

    Background/Purpose: Uveitis is the main extraarticular complication of juvenile idiopathic arthritis (JIA) with still a significant impact on JIA morbidity, despite continuous improvement in systemic…
  • Abstract Number: 0245 • ACR Convergence 2021

    Long-term Safety and Effectiveness of Abatacept Treatment in Patients with JIA: 5-year Results from the PRCSG/PRINTO JIA Real-World Registry

    Hermine Brunner1, Daniel Lovell2, Michael Henrickson1, Ruy Carrassco3, Kirsten Minden4, Lyudmila Grebenkina5, James Nocton6, Ingrid Louw7, Linda Wagner-Weiner8, Gabriel Vega Cornejo9, Sylvia Kamphuis10, Vyacheslav Chasnyk11, Heather Walters12, Simone Appenzeller13, Jordi Anton14, Alyssa Dominique15, Robert Wong16, Lixian Dong15, Tzuyung Douglas Kou15, Alberto Martini17 and Nicolino Ruperto18, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, 3Presbyterian Health Services, Albuquerque, NM, 4Charite University Hospital Berlin, Berlin, Germany, 5Togliatti City Clinical Hospital №5, Togliatti, Russia, 6Medical College of Wisconsin, Milwaukee, WI, 7Panorama Medical Centre, Cape Town, South Africa, 8University of Chicago (Comer Children's), Chicago, IL, 9Crea de Guadalajara/Hospital México Americano, Guadalajara, Mexico, 10Sophia Children’s Hospital, Erasmus University Medical Center, Rotterdam, Netherlands, 11Saint-Petersburg State Pediatric Medical Academy, Saint Petersburg, Russia, 12Cohen Children's Hospital, New York, NY, 13Hospital das Clínicas da Universidade Estadual de Campinas, Campinas, Brazil, 14Hospital Sant Joan de Deu, University of Barcelona, Barcelona, Spain, 15Bristol Myers Squibb, Princeton, NJ, 16Bristol Myers Squibb, Basking Ridge, NJ, 17Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, 18IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy

    Background/Purpose: Abatacept (ABA) is well tolerated and effective in patients with JIA.1 The Pediatric Rheumatology Collaborative Study Group (PRCSG)/ Paediatric Rheumatology INternational Trials Organisation (PRINTO)…
  • Abstract Number: 0264 • ACR Convergence 2021

    Joint Acoustic Emissions as a Biomarker to Differentiate Between Active and Inactive Juvenile Idiopathic Arthritis via 2-stage Machine Learning Classifier

    Luis Rosa1, Sevda Gharehbaghi1, Omer Inan1, Daniel Whittingslow2, Lori Ponder3 and Sampath Prahalad4, 1Georgia Institute of Technology, Atlanta, GA, 2Emory University School of Medicine, Atlanta, GA, 3Children's Healthcare of Atlanta, Atlanta, GA, 4Emory + Children's Pediatric Institute, Atlanta, GA

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is the most prevalent chronic rheumatic disease and can result in disability in children. JIA most commonly affects the knee.…
  • Abstract Number: 1639 • ACR Convergence 2021

    A Comparison of Cardiovascular Health Indicators in Children with Juvenile Idiopathic Arthritis Who Meet and Do Not Meet the Physical Activity Guidelines

    Madelyn Byra1, Nicole Proudfoot2, Si Ru Chen1, Maureen MacDonald3, Tania Cellucci4, Michelle Batthish5, Brian Timmons6 and Joyce Obeid6, 1Child Health & Exercise Medicine Program, McMaster University, Hamilton, ON, Canada, 2Child Health & Exercise Medicine Program, McMaster University; Department of Kinesiology, McMaster University, Hamilton, ON, Canada, 3Department of Kinesiology, McMaster University, Hamilton, ON, Canada, 4McMaster Children's Hospital, Hamilton, ON, Canada, 5McMaster University, Hamilton, ON, Canada, 6Child Health & Exercise Medicine Program, McMaster University; Department of Pediatrics, McMaster University, Hamilton, ON, Canada

    Background/Purpose: Children with juvenile idiopathic arthritis (JIA) engage in less physical activity than their healthy peers. The Canadian 24-h Movement Guidelines recommend children take part…
  • Abstract Number: 0470 • ACR Convergence 2020

    Th1 Polarization Defines the T Cell Compartment in the Joints of Oligoarticular Juvenile Idiopathic Arthritis Patients

    Amelie Jule1, Kacie Hoyt1, Kevin Wei2, Siobhan Case3, Margaret Chang1, Ezra Cohen1, Fatma Dedeoglu1, Melissa Hazen1, Jonathan Hausmann4, Olha Halyabar5, Erin Janssen5, Pui Lee6, Jeffrey Lo1, Mindy Lo1, Esra Meidan7, Jordan Roberts1, Mary Beth Son1, Robert Sundel5, Talal Chatila1, Peter Nigrovic8 and Lauren Henderson9, 1Boston Children's Hospital, Boston, MA, 2Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 3Brigham and Women's Hospital, Boston, MA, 4Boston Children's Hospital / Beth Israel Deaconess Medical Center, Cambridge, MA, 5Children's Hospital/Boston Medical Center, Boston, MA, 61.Boston Children's Hospital;2.Brigham and Women's Hospital;3.Harvard Medical School, Newton, MA, 7Boston Children's Hospital, Somerville, MA, 8Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA, Boston, 9Boston Children's Hospital, Watertown, MA

    Background/Purpose: Oligoarticular juvenile idiopathic arthritis (oligo JIA) is defined by limited joint involvement at disease onset. Some children achieve long-term remission while others continue to…
  • Abstract Number: 0728 • ACR Convergence 2020

    Clinical Outcomes of Juvenile Arthritis in Adulthood: A Systematic Review

    Lily Siok Hoon Lim1, Woo Jin Kim2, Yushi Wang2 and Kaien Gu3, 1University of Manitoba, Children's Hospital of Manitoba, Winnipeg, MB, Canada, 2University of Manitoba Max Rady College of Medicine, Winnipeg, MB, Canada, 3University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: Juvenile arthritis (JA) is the most common pediatric rheumatic disease, with potentially permanent functional impacts on patients long after initial diagnosis. Little is known…
  • Abstract Number: 1495 • ACR Convergence 2020

    Tofacitinib for the Treatment of Patients with Juvenile Idiopathic Arthritis: An Interim Analysis of Data up to 5.5 Years from an Open-label, Long-term Extension Study

    Hermine I Brunner1, Jonathan Akikusa2, Eslam Al-Abadi2, John Bohnsack3, Alina Lucica Boteanu2, Gaelle Chedeville4, Ruben Cuttica2, Wendy De La Pena4, Lawrence Jung4, Ozgur Kasapcopur2, Katarzyna Kobusinska2, Grant Schulert1, Claudia Neiva2, Rafael Rivas-Chacon4, Juan Cruz Rizo Rodriguez2, Monica Vazquez-Del Mercado2, Linda Wagner-Weiner4, Jennifer E Weiss1, Carine Wouters2, Ricardo M Suehiro5, Holly Posner6, Ann Wouters6, Keith S Kanik7, Zhen Luo8, Alberto Martini2, Daniel J Lovell1 and Nicolino Ruperto2, 1PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, 2PRINTO, Istituto Giannina Gaslini, Genova, Italy, 3University of Utah and Primary Children's Hospital, Cincinnati, OH, 4PRCSG, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Pfizer Inc, Collegeville, PA, 6Pfizer Inc, New York, NY, 7Pfizer Inc, Groton, CT, 8Pfizer Inc, Shanghai, China (People's Republic)

    Background/Purpose: Tofacitinib is an oral JAK inhibitor that is being investigated for JIA. We report the safety, tolerability, and efficacy of tofacitinib in patients (pts)…
  • Abstract Number: 0710 • ACR Convergence 2020

    Early Start of Biological Treatment in Juvenile Idiopathic Arthritis: Does a Therapeutic Window Exist in Real Life?

    Alina Lucica Boteanu1, Andrea Briones-Figueroa2, Laura Calvo-Sanz2, África Andreu Suárez2 and Antía García-Fernández2, 1PRINTO, Istituto Giannina Gaslini, Genova, Italy, 2Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain

    Background/Purpose: Data about when is the best moment to start BT in Juvenile Idiopathic Arthritis (JIA) patients and the impact of this prompt initiation are…
  • Abstract Number: 0729 • ACR Convergence 2020

    Morbidity of JIA-associated Uveitis: Half of Patients Despite Systemic Treatment Still Show Ocular Damage During a Long-term Follow-up

    Francesca Minoia1, Luca Marelli2, Gisella Beatrice Beretta3, Micol Romano4, Elisabetta Miserocchi4, Chiara Mapelli3, Antonella Petaccia3, Stefano Lanni3, Irene Pontikaki4, Giovanni Filocamo3 and Rolando Cimaz5, 1Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, Milan, Italy, 2San Giuseppe Hospital, IRCCS Multimedica, Milan, Italy, Milan, Italy, 3Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy, Milan, Italy, 4ASST Gaetano Pini-CTO Institute, Milan, Italy, Milan, Italy, 5ASST Gaetano Pini-CTO Institute and Università degli Studi di Milano, Milan, Italy, Milan, Italy

    Background/Purpose: Uveitis is the most common extra-articular complication of juvenile Idiopathic arthritis (JIA). Due to its typical indolent and chronic course, children with this condition…
  • Abstract Number: 1616 • ACR Convergence 2020

    Systematic Review of Effectiveness Outcomes Reported in Rheumatology Transition Literature

    Heather Bannerman1, Karen Beattie1, Avanti Patel2, Milica Tanic2, Michelle Batthish3 and Mark Matsos2, 1McMaster University, Hamilton, ON, Canada, 2McMaster University, Hamilton, Canada, 3McMaster Children's Hospital, Hamilton, ON, Canada

    Background/Purpose: In young patients with rheumatologic disease, transition from pediatric to adult care is a complex process. Poor transitional care leads to health deterioration, loss…
  • Abstract Number: 0711 • ACR Convergence 2020

    Alternative Dosing of Biologic Therapies Is Frequent Among Children with Juvenile Idiopathic Arthritis in the Childhood Arthritis and Rheumatology Research Alliance Registry

    Colleen Correll1, Peter Shrader2, Anne Dennos3, Thomas Phillips2, Natalie Shiff4, Ruud Verstegen5 and Timothy Beukelman6, 1University of Minnesota, Minneapolis, MN, 2Duke University, Durham, 3Duke University, Durham, NC, 4Florida, Gainesville, FL, 5The Hospital for Sick Children, Toronto, ON, Canada, 6University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Biologic agents are integral to the treatment of juvenile idiopathic arthritis (JIA) and associated uveitis. Pediatric rheumatologists may increase the dosage of biologics beyond…
  • Abstract Number: 0730 • ACR Convergence 2020

    To Taper or Not to Taper in Juvenile Idiopathic Arthritis: Is There a Risk of Development of Uveitis Flares?

    Maria Teran1, Alina Lucica Boteanu2, Carlos Guillen1, Cristina Pijoan1, Jose Quinones1, Veronica Garcia3, Ivan Del Bosque-Granero3, Laura Calvo-Sanz4 and Mónica Vázquez4, 1Hospital Ramon y Cajal, Madrid, Madrid, Spain, 2PRINTO, Istituto Giannina Gaslini, Genova, Italy, 3Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain, 4Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain

    Background/Purpose: To determine the association between the occurrence of uveitis flares in patients with Juvenile Idiopathic Arthritis (JIA) and the de-intensification of immunosuppressive treatment.Methods: We…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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