Abstracts tagged "Juvenile idiopathic arthritis"

Abstract Number: 0264 • ACR Convergence 2021
Joint Acoustic Emissions as a Biomarker to Differentiate Between Active and Inactive Juvenile Idiopathic Arthritis via 2-stage Machine Learning Classifier
Luis Rosa¹, Sevda Gharehbaghi¹, Omer Inan¹, Daniel Whittingslow², Lori Ponder³ and Sampath Prahalad⁴, ¹Georgia Institute of Technology, Atlanta, GA, ²Emory University School of Medicine, Atlanta, GA, ³Children's Healthcare of Atlanta, Atlanta, GA, ⁴Emory + Children's Pediatric Institute, Atlanta, GA
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is the most prevalent chronic rheumatic disease and can result in disability in children. JIA most commonly affects the knee.…
Abstract Number: 1639 • ACR Convergence 2021
A Comparison of Cardiovascular Health Indicators in Children with Juvenile Idiopathic Arthritis Who Meet and Do Not Meet the Physical Activity Guidelines
Madelyn Byra¹, Nicole Proudfoot², Si Ru Chen¹, Maureen MacDonald³, Tania Cellucci⁴, Michelle Batthish⁵, Brian Timmons⁶ and Joyce Obeid⁶, ¹Child Health & Exercise Medicine Program, McMaster University, Hamilton, ON, Canada, ²Child Health & Exercise Medicine Program, McMaster University; Department of Kinesiology, McMaster University, Hamilton, ON, Canada, ³Department of Kinesiology, McMaster University, Hamilton, ON, Canada, ⁴McMaster Children's Hospital, Hamilton, ON, Canada, ⁵McMaster University, Hamilton, ON, Canada, ⁶Child Health & Exercise Medicine Program, McMaster University; Department of Pediatrics, McMaster University, Hamilton, ON, Canada
Background/Purpose: Children with juvenile idiopathic arthritis (JIA) engage in less physical activity than their healthy peers. The Canadian 24-h Movement Guidelines recommend children take part…
Abstract Number: 0247 • ACR Convergence 2021
Three-year Effectiveness in Patients with JIA Initiating Abatacept: Results from the PRCSG/PRINTO JIA Real-World Registry
Nicolino Ruperto¹, Hermine Brunner², Nikolay Tzaribachev³, Ilonka Orbán⁴, Valda Staņēviča⁵, Ana Quintero del Rio⁶, Pierre Quartier⁷, Adam Huber⁸, Dan Kietz⁹, Jason Dare¹⁰, Daniel Kingsbury¹¹, T. Brent Graham¹², Ivan Foeldvari¹³, Julisa Patel¹⁴, Alyssa Dominique¹⁵, Lixian Dong¹⁵, Tzuyung Douglas Kou¹⁵, Robert Wong¹⁶, Alberto Martini¹⁷ and Daniel Lovell¹⁸, ¹IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy, ²Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³PRI Research, Bad Bramstedt, Germany, ⁴National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, ⁵Riga Stradins University, Riga, Latvia, ⁶Dr. Ramon Ruiz Arnau University Hospital, Bayamόn, PR, ⁷Necker-Enfants Malades University Hospital, Assistance Publique-Hopitaux de Paris, Paris, France, ⁸Dalhousie University, Halifax, NS, Canada, ⁹Children’s Hospital of Pittsburgh, Pittsburg, PA, ¹⁰University of Arkansas for Medical Sciences, Little Rock, AR, ¹¹Randall Children's Hospital at Legacy Emanuel, Portland, OR, ¹²Vanderbilt University Medical Center, Nashville, TN, ¹³Hamburg Centre for Pediatric and Adolescent Rheumatology, Hamburg, Germany, ¹⁴Children’s Hospital of Georgia, Augusta University Medical Center, Augusta, GA, ¹⁵Bristol Myers Squibb, Princeton, NJ, ¹⁶Bristol Myers Squibb, Basking Ridge, NJ, ¹⁷Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, ¹⁸Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH
Background/Purpose: The ongoing phase 4 Pediatric Rheumatology Collaborative Study Group (PRCSG)/Paediatric Rheumatology INternational Trials Organisation (PRINTO) registry was designed to assess the long-term (up to…
Abstract Number: 0265 • ACR Convergence 2021
Development and Preliminary Acceptability of JIActiv, a Social Media-Based Program Promoting Engagement in Physical Activity Among Young People Living with Juvenile Idiopathic Arthritis
Sabrina Cavallo¹, Karine Toupin April², Ciaran Duffy², Karina Cristea¹, Jihene Tlili¹, Imane Brahmi¹, Zeinab Ahmadian¹, Michele Gibbon³, Alexandra Sirois⁴, Laurie Proulx⁵, Sara Ahmed⁶, Claudine Auger¹ and Jennifer Stinson⁷, ¹Université de Montréal, Montréal, QC, Canada, ²University of Ottawa, Ottawa, ON, Canada, ³Children's Hospital of Eastern Ontario, Ottawa, ON, Canada, ⁴Canadian Arthritis patient Alliance, Montréal, QC, Canada, ⁵Canadian Arthritis Patient Alliance, Ottawa, ON, Canada, ⁶Children's Hospital of Eastern Ontario, Montréal, QC, Canada, ⁷The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Young people with juvenile idiopathic arthritis (JIA) are at greater risk for adopting chronic sedentary behaviours and not meeting national physical activity guidelines compared…
Abstract Number: 1927 • ACR Convergence 2021
Heterogeneity of Juvenile Idiopathic Arthritis Synovial Fibroblasts Correlates to Disease Progression and Provides Compelling Diagnostic Data
Megan Simonds¹, Kathleen Sullivan², Carlos Rose³ and AnneMarie Brescia⁴, ¹Nemours, Wilmington, DE, ²The Children's Hospital of Philadelphia, Philadelphia, PA, ³Thomas Jefferson University/duPont Hospital for Children, Wilmington, DE, ⁴Nemours/A.I.duPont Hospital for Children, Wilmington, DE
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) induces growth disturbances in affected joints. Fibroblast-like synoviocytes (FLS) play a crucial role in JIA pathogenesis; however, the mechanisms by…
Abstract Number: 0248 • ACR Convergence 2021
Proportion of Patients with a Polyphasic Disease Course in Systemic-onset Juvenile Idiopathic Arthritis May Be Higher in the Age of Cytokine Inhibitors
Itay Marmor¹, Rotem Semo Oz², Amir Hendel³, Guy Hazan¹, Kevin Baszis⁴, Anthony French¹, Cuoghi Edens⁵, irit Tirosh⁶, Yonatan Butbul Aviel⁷, Liora Harel⁸ and Gil Amarilyo⁹, ¹Washington University School of Medicine, St. Louis, MO, ²Sheba Medical Center, Herzelyia, Israel, ³Sackler Faculty of Medicine, Tel Aviv University; Clalit Health Services, Sharon and Shomron County, Tel Aviv, Israel, ⁴Washington University School of Medicine, St Louis, MO, ⁵University of Chicago, Chicago, IL, ⁶Sheba Medical Center, Ramat Gan, Israel, ⁷Rambam Medical center, Haifa, Israel, ⁸Scheiders Children Medical Center of Israel, Petah-Tiqva, Israel, ⁹Schneider Children's Medical Center of Israel, Kibbutz Maggal, Israel
Background/Purpose: Systemic-onset juvenile idiopathic arthritis (sJIA) is a pediatric autoinflammatory condition, known for significant variability between patients in its severity and long-term outcomes. The classification…
Abstract Number: 0658 • ACR Convergence 2021
ACCORD: A Novel Rheumatology Transition Clinic Structure for Adolescent and Young Adult Patients with Childhood Onset Rheumatic Disease
Rebecca Overbury¹, Kelly Huynh², Tracy Frech¹, John Bohnsack¹ and Aimee Hersh¹, ¹University of Utah, Salt Lake City, UT, ²Intermountain Health Care, Salt Lake City, UT
Background/Purpose: The transition of health care from Pediatric to Adult providers for adolescents and young adults with childhood onset rheumatic disease continues to be associated…
Abstract Number: 1930 • ACR Convergence 2021
Single-Cell Genomics Reveals a Shared Monocyte Interferon Program in a Subset of Patients with Systemic Juvenile Idiopathic Arthritis, Macrophage Activation Syndrome and Lung Disease
Emely Verweyen¹, Kairavee Thakkar², Kashish Chetal², Sanjeev Dhakal³, Alexei Grom², Nathan Salomonis² and Grant Schulert², ¹Cincinnati Children's Hospital, Cincinnati, OH, ²Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Cincinnati Children hospital, Cincinnati, OH
Background/Purpose: Systemic juvenile idiopathic arthritis (SJIA) is a clinically heterogenous disease and can be complicated by macrophage activation syndrome (MAS) and lung disease (LD) thought…
Abstract Number: 0249 • ACR Convergence 2021
Open-label, Long-term (10-year) Study of the Safety of Etanercept in Children with Extended Oligoarticular Arthritis, Enthesitis-related Arthritis, or Psoriatic Arthritis
Jelena Vojinović¹, Joke Dehoorne², Violeta Panaviene³, Gordana Susic⁴, Gerd Horneff⁵, Valda Stanevicha⁶, Katarzyna Kobusinska⁷, Zbigniew Zuber⁸, Bogna Dobrzyniecka⁹, Jonathan Akikusa¹⁰, Tadej Avcin¹¹, Alberto Martini¹², Cecilia Borlenghi¹³, Edmund Arthur¹⁴, Svitlana Tatulych¹⁵, Chuanbo Zang¹⁶, Bonnie Vlahos¹⁶ and Nicolino Ruperto¹⁷, ¹Paediatric Rheumatology International Trials Organisation (PRINTO), Nis, Serbia, ²Paediatric Rheumatology International Trials Organisation (PRINTO), Gent, Belgium, ³Paediatric Rheumatology International Trials Organisation (PRINTO), Vilnius, Lithuania, ⁴Paediatric Rheumatology International Trials Organisation (PRINTO), Belgrade, Serbia, ⁵Paediatric Rheumatology International Trials Organisation (PRINTO), Sankt Augustin, Germany, ⁶Paediatric Rheumatology International Trials Organisation (PRINTO), Riga, Latvia, ⁷Paediatric Rheumatology International Trials Organisation (PRINTO), Bydgoszcz, Poland, ⁸Paediatric Rheumatology International Trials Organisation (PRINTO), Lodz, Poland, ⁹Paediatric Rheumatology International Trials Organisation (PRINTO), Warsaw, Poland, ¹⁰Paediatric Rheumatology International Trials Organisation (PRINTO), Melbourne, Australia, ¹¹Paediatric Rheumatology International Trials Organisation (PRINTO), Ljubljana, Slovenia, ¹²Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, ¹³Pfizer, Buenos Aires, Argentina, Buenos Aires, Argentina, ¹⁴Pfizer, Peapack, NJ, ¹⁵Pfizer, Groton, CT, ¹⁶Pfizer, Collegeville, PA, ¹⁷IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy
Background/Purpose: CLIPPER2 was an 8-year, open-label extension of the phase 3b, multicenter, 2-year CLIPPER study of the safety and efficacy of etanercept (ETN) in the…
Abstract Number: 0960 • ACR Convergence 2021
The Childhood Arthritis and Rheumatology Research Alliance Start Time Optimization of Biologic Therapy in Polyarticular JIA (STOP-JIA) Study: 24-Month Outcomes
Yukiko Kimura¹, Sarah Ringold², George Tomlinson³, Laura Schanberg⁴, Anne Dennos⁵, Mary Ellen Riordan⁶, Vincent Del Gaizo⁷, Katherine Murphy⁸, Pamela Weiss⁹, Brian Feldman¹⁰, Marc Natter¹¹ and The STOP-JIA CARRA Registry Investigators¹², ¹Hackensack University Medical Center, New York, NY, ²Seattle Children's Hospital, Seattle, WA, ³University of Toronto, Toronto, ON, Canada, ⁴Duke University Medical Center, Durham, NC, ⁵Duke University, Durham, NC, ⁶Hackensack University Medical Center, Westwood, NJ, ⁷Childhood Arthritis & Rheumatology Research Alliance (CARRA), Whitehouse Station, NJ, ⁸Childhood Arthritis & Rheumatology Research Alliance (CARRA), New Orleans, LA, ⁹Children's Hospital of Philadelphia, Philadelphia, PA, ¹⁰The Hospital for Sick Children, Toronto, ON, Canada, ¹¹Boston Children's Hospital, Boston, MA, ¹²Childhood Arthritis & Rheumatology Research Alliance (CARRA), Milwaukee, WS
Background/Purpose: The CARRA STOP-JIA study compared the effectiveness of the CARRA Consensus Treatment Plans (CTPs) in achieving clinical inactive disease (CID) in untreated polyarticular JIA…
Abstract Number: PP09 • ACR Convergence 2021
Family Planning while Living with Rheumatoid Arthritis
Shannan O'Hara-Levi, Monroe, NY
Background/Purpose: Over the course of my 30+ years living with Polyarticular Juvenile Rheumatoid Arthritis, I have never had long term success on any one biologic treatment,…
Abstract Number: 0251 • ACR Convergence 2021
A Comparative Study of the Validity of the DAS28-ESR and JADAS-27 Disease Activity Assessment Indexes for Juvenile Idiopathic Arthritis in Transition and Adults
Takako Miyamae¹, Eiichi Tanaka¹, Eisuke Inoue², Katsunori Ikari¹ and Masayoshi Harigai³, ¹Tokyo Women's Medical University, Tokyo, Japan, ²Showa University, Tokyo, Japan, ³Tokyo Women's Medical University School of Medicine, Tokyo, Japan
Background/Purpose: The 2020 Rheumatoid Arthritis Clinical Practice Guidelines by the Ministry of Health, Labour, and Welfare Research Group recommends the JADAS27 as a measure of…
Abstract Number: 0976 • ACR Convergence 2021
Cumulative Social Disadvantage Predicts an Arthritis Diagnosis: A Cross-sectional Analysis of the National Survey of Children’s Health (NSCH)
William Soulsby, Erica Lawson and Matthew Pantell, University of California San Francisco, San Francisco, CA
Background/Purpose: The impact of social determinants of health in juvenile idiopathic arthritis (JIA) remains poorly understood. Racial disparities exist in JIA, including increased pain and…
Abstract Number: PP11 • ACR Convergence 2021
“Our Arthritis May Be Chronic but We Are Definitely Iconic” – Two Teens Created a National Podcast for Youth with Rheumatic Diseases
Trishtha Peters¹ and Natasha Trehan², ¹University of Ontario, Toronto, ON, Canada, ²University of Ottawa, Toronto, ON, Canada
Background/Purpose: Trish Peters was diagnosed with JIA at 11. She has been on Methotrexate to lessen disease activity for her knees and hands. She does…
Abstract Number: 0253 • ACR Convergence 2021
Rheumatoid Factor Status as a Predictor of Disease Activity and Disability:An Analysis of the New CARRA Registry Polyarticular Juvenile Idiopathic Arthritis Cohort
Nayimisha Balmuri¹, William Soulsby², Victoria Cooley³, Linda Gerber⁴, Erica Lawson² and Karen Onel¹, ¹Hospital for Special Surgery, New York, NY, ²University of California San Francisco, San Francisco, CA, ³Weil Cornell Medicine, New York, NY, ⁴Weill Cornell Medicine, New York, NY
Background/Purpose: Children with rheumatoid factor (RF) positive polyarticular JIA (pJIA) are less likely to go into remission and more likely to develop erosive disease than…

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