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Abstracts tagged "Juvenile idiopathic arthritis"

  • Abstract Number: 1622 • ACR Convergence 2021

    Mind the Gap: The Experience of Adolescents in a Rheumatology Transition Clinic

    Claire Fine1, Karen Beattie1, Tania Cellucci2, Liane Heale1, Mark Matsos1, Stephanie Garner1 and Michelle Batthish1, 1McMaster University, Hamilton, ON, Canada, 2McMaster Children's Hospital, Hamilton, ON, Canada

    Background/Purpose: The transition from pediatric to adult healthcare is a critical time for the wellbeing of patients with chronic illness including rheumatologic disease. Low patient…
  • Abstract Number: 0242 • ACR Convergence 2021

    FiRst Line Options for Systemic JIA Treatment (FROST): Results from a Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry Consensus Treatment Plan Observational Study

    Timothy Beukelman1, George Tomlinson2, Peter Nigrovic3, Anne Dennos4, Vincent Del Gaizo5, Mary Ellen Riordan6, Laura Schanberg7, Shalini Mohan8, Erin Pfeifer9 and Yukiko Kimura10, 1University of Alabama at Birmingham, Birmingham, AL, 2University of Toronto, Toronto, ON, Canada, 3Boston Children's Hospital, Brookline, MA, 4Duke University, Durham, NC, 5Childhood Arthritis & Rheumatology Research Alliance (CARRA), Whitehouse Station, NJ, 6Hackensack University Medical Center, Westwood, NJ, 7Duke University Medical Center, Durham, NC, 8Genentech, Inc., South San Francisco, CA, 9Genentech, Inc., Englewood, CO, 10Hackensack University Medical Center, New York, NY

    Background/Purpose: The optimal initial treatment for systemic juvenile idiopathic arthritis (sJIA) is unclear. To further study the initial treatment of sJIA, the Childhood Arthritis and…
  • Abstract Number: 0262 • ACR Convergence 2021

    High Degree of Inter-patient Heterogeneity in Synoviocyte Hyperplasia and Immune Cells Infiltration in the Synovium of Juvenile Idiopathic Arthritis Patients

    Clément TRIAILLE1, Cécile BOULANGER2, Tatiana SOKOLOVA1, Laurent MERIC de BELLEFON3, Adrien NZEUSSEU TOUKAP4, Christine GALANT5, Nisha LIMAYE6, Bernard LAUWERYS7 and Patrick DUREZ8, 1Pôle de pathologies rhumatismales systémiques et inflammatoires, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium, 2Service d’Hématologie, Oncologie et Rhumatologie pédiatrique, Cliniques Universitaires Saint-Luc, Brussels, Belgium, 3Service de Rhumatologie, Cliniques Universitaires Saint-Luc, Brussels, Belgium, 4Rheumatology department, Cliniques Universitaires Saint-Luc, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain, Brussels, Belgium, 5Service d’Anatomie Pathologique, Cliniques Universitaires Saint-Luc, Brussels, Belgium, 6Genetics of Autoimmune Diseases and Cancer, de Duve Institute, Université catholique de Louvain, Brussels, Belgium, 7UCB Pharma, Brussels, Belgium, 8Pôle de Recherche en Rhumatologie, Institut de Recherche Expérimentale et Clinique, Brussels, Belgium

    Background/Purpose: Increasing evidence indicates that synovial tissue analysis can deliver pathophysiological insights but also individual clinically-relevant information in adult-onset inflammatory arthritides. Little is known about…
  • Abstract Number: 1626 • ACR Convergence 2021

    Use of Total Hip Arthroplasty in Patients Under 21 Years Old: A U.S. Population Analysis

    J. Alex Gibbons1, Cynthia Kahlenberg1, Deanna Jannat-Khah1, Susan Goodman1, Lisa Mandl1, Peter Sculco1, Stuart Goodman2, Mark Figgie1 and Bella Mehta3, 1Hospital for Special Surgery, New York, NY, 2Stanford University, Stanford, CA, 3Hospital for Special Surgery, Weill Cornell Medicine, New York, NY

    Background/Purpose: Total hip arthroplasty (THA) is a treatment option for young patients with severe hip pathology due to congenital, developmental, rheumatologic, traumatic, and other acquired…
  • Abstract Number: 0243 • ACR Convergence 2021

    Effectiveness of Abatacept in Patients with JIA, Classified by Category: Results from the PRCSG/PRINTO JIA Real-World Registry

    Daniel Lovell1, Nikolay Tzaribachev2, Tracy Ting3, Ekaterina Alexeeva4, Teresa Giani5, Thomas Griffin6, John Bohnsack7, Andrew Zeft8, Richard Vehe9, Stacey Tarvin10, Gerd Horneff11, Maria Trachana12, Alyssa Dominique13, Lixian Dong13, Tzuyung Douglas Kou13, Robert Wong14, Alberto Martini15, Hermine Brunner3 and Nicolino Ruperto16, 1Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, 2PRI Research, Bad Bramstedt, Germany, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Scientific Center of Children Health of RAMS, Moscow, Russia, 5Università di Siena, Siena, Italy, 6Levine Children's Hospital, Charlotte, NC, 7University of Utah, Salt Lake City, UT, 8Cleveland Clinic, Cleveland, OH, 9University of Minnesota, Twin Cities, MN, 10Riley Hospital for Children at Indiana University, Indianapolis, IN, 11Paediatric Rheumatology International Trials Organisation (PRINTO), Sankt Augustin, Germany, 12Aristotle University of Thessaloniki, Thessaloniki, Greece, 13Bristol Myers Squibb, Princeton, NJ, 14Bristol Myers Squibb, Basking Ridge, NJ, 15Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, 16IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy

    Background/Purpose: Long-term treatment with abatacept, a selective T-cell co-stimulation modulator, is effective and well tolerated in patients with JIA.1–4 The objective of this analysis was…
  • Abstract Number: 0263 • ACR Convergence 2021

    Patterns of Medication Switching in Juvenile Idiopathic Arthritis: A Retrospective Analysis of a National Administrative Claims Database

    Mei-Sing Ong1, Sarah Ringold2, Melissa Mannion3, Marc Natter4, Laura Schanberg5 and Yukiko Kimura6, 1Harvard Medical School & Harvard Pilgrim Healthcare Institute, Boston, MA, 2Seattle Children's Hospital, Seattle, WA, 3University of Alabama at Birmingham, Birmingham, AL, 4Boston Children's Hospital, Boston, MA, 5Duke University Medical Center, Durham, NC, 6Hackensack University Medical Center, New York, NY

    Background/Purpose: Although the increasing availability of biologic disease-modifying antirheumatic drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs) has significantly improved outcomes for patients with Juvenile Idiopathic…
  • Abstract Number: 1631 • ACR Convergence 2021

    Predictive Factors for Lack of Response to Treatment in a Long-term Cohort of Patients with Juvenile Idiopathic Arthritis-associated Uveitis

    Francesca Minoia1, Luca Marelli2, Francesca Pregnolato3, Gisella Beatrice Beretta4, Chiara Mapelli4, Gaia Leone4, Gilberto Cincinelli3, Paolo Nucci5, Teresa Giani6, Elisabetta Miserocchi7 and Rolando Cimaz8, 1Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy, 2Ospedale San Giuseppe, IRCCS Multimedica, Milan, Italy, 3Università degli Studi di Milano, Milan, Italy, 4Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy, 5Ospedale San Giuseppe, IRCCS Multimedica, Università degli Studi di Milano, Milan, Italy, 6Università di Siena, Siena, Italy, 7San Raffaele Scientific Institute, Milan, Italy, 8ASST Gaetano Pini-CTO, Università degli Studi di Milano, Milan, Italy

    Background/Purpose: Uveitis is the main extraarticular complication of juvenile idiopathic arthritis (JIA) with still a significant impact on JIA morbidity, despite continuous improvement in systemic…
  • Abstract Number: 0245 • ACR Convergence 2021

    Long-term Safety and Effectiveness of Abatacept Treatment in Patients with JIA: 5-year Results from the PRCSG/PRINTO JIA Real-World Registry

    Hermine Brunner1, Daniel Lovell2, Michael Henrickson1, Ruy Carrassco3, Kirsten Minden4, Lyudmila Grebenkina5, James Nocton6, Ingrid Louw7, Linda Wagner-Weiner8, Gabriel Vega Cornejo9, Sylvia Kamphuis10, Vyacheslav Chasnyk11, Heather Walters12, Simone Appenzeller13, Jordi Anton14, Alyssa Dominique15, Robert Wong16, Lixian Dong15, Tzuyung Douglas Kou15, Alberto Martini17 and Nicolino Ruperto18, 1Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH, 3Presbyterian Health Services, Albuquerque, NM, 4Charite University Hospital Berlin, Berlin, Germany, 5Togliatti City Clinical Hospital №5, Togliatti, Russia, 6Medical College of Wisconsin, Milwaukee, WI, 7Panorama Medical Centre, Cape Town, South Africa, 8University of Chicago (Comer Children's), Chicago, IL, 9Crea de Guadalajara/Hospital México Americano, Guadalajara, Mexico, 10Sophia Children’s Hospital, Erasmus University Medical Center, Rotterdam, Netherlands, 11Saint-Petersburg State Pediatric Medical Academy, Saint Petersburg, Russia, 12Cohen Children's Hospital, New York, NY, 13Hospital das Clínicas da Universidade Estadual de Campinas, Campinas, Brazil, 14Hospital Sant Joan de Deu, University of Barcelona, Barcelona, Spain, 15Bristol Myers Squibb, Princeton, NJ, 16Bristol Myers Squibb, Basking Ridge, NJ, 17Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, 18IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy

    Background/Purpose: Abatacept (ABA) is well tolerated and effective in patients with JIA.1 The Pediatric Rheumatology Collaborative Study Group (PRCSG)/ Paediatric Rheumatology INternational Trials Organisation (PRINTO)…
  • Abstract Number: 0264 • ACR Convergence 2021

    Joint Acoustic Emissions as a Biomarker to Differentiate Between Active and Inactive Juvenile Idiopathic Arthritis via 2-stage Machine Learning Classifier

    Luis Rosa1, Sevda Gharehbaghi1, Omer Inan1, Daniel Whittingslow2, Lori Ponder3 and Sampath Prahalad4, 1Georgia Institute of Technology, Atlanta, GA, 2Emory University School of Medicine, Atlanta, GA, 3Children's Healthcare of Atlanta, Atlanta, GA, 4Emory + Children's Pediatric Institute, Atlanta, GA

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is the most prevalent chronic rheumatic disease and can result in disability in children. JIA most commonly affects the knee.…
  • Abstract Number: 1639 • ACR Convergence 2021

    A Comparison of Cardiovascular Health Indicators in Children with Juvenile Idiopathic Arthritis Who Meet and Do Not Meet the Physical Activity Guidelines

    Madelyn Byra1, Nicole Proudfoot2, Si Ru Chen1, Maureen MacDonald3, Tania Cellucci4, Michelle Batthish5, Brian Timmons6 and Joyce Obeid6, 1Child Health & Exercise Medicine Program, McMaster University, Hamilton, ON, Canada, 2Child Health & Exercise Medicine Program, McMaster University; Department of Kinesiology, McMaster University, Hamilton, ON, Canada, 3Department of Kinesiology, McMaster University, Hamilton, ON, Canada, 4McMaster Children's Hospital, Hamilton, ON, Canada, 5McMaster University, Hamilton, ON, Canada, 6Child Health & Exercise Medicine Program, McMaster University; Department of Pediatrics, McMaster University, Hamilton, ON, Canada

    Background/Purpose: Children with juvenile idiopathic arthritis (JIA) engage in less physical activity than their healthy peers. The Canadian 24-h Movement Guidelines recommend children take part…
  • Abstract Number: 0247 • ACR Convergence 2021

    Three-year Effectiveness in Patients with JIA Initiating Abatacept: Results from the PRCSG/PRINTO JIA Real-World Registry

    Nicolino Ruperto1, Hermine Brunner2, Nikolay Tzaribachev3, Ilonka Orbán4, Valda Staņēviča5, Ana Quintero del Rio6, Pierre Quartier7, Adam Huber8, Dan Kietz9, Jason Dare10, Daniel Kingsbury11, T. Brent Graham12, Ivan Foeldvari13, Julisa Patel14, Alyssa Dominique15, Lixian Dong15, Tzuyung Douglas Kou15, Robert Wong16, Alberto Martini17 and Daniel Lovell18, 1IRCCS Istituto Giannina Gaslini; PRINTO, Clinica Pediatrica e Reumatologia, Genova, Italy, 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3PRI Research, Bad Bramstedt, Germany, 4National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 5Riga Stradins University, Riga, Latvia, 6Dr. Ramon Ruiz Arnau University Hospital, Bayamόn, PR, 7Necker-Enfants Malades University Hospital, Assistance Publique-Hopitaux de Paris, Paris, France, 8Dalhousie University, Halifax, NS, Canada, 9Children’s Hospital of Pittsburgh, Pittsburg, PA, 10University of Arkansas for Medical Sciences, Little Rock, AR, 11Randall Children's Hospital at Legacy Emanuel, Portland, OR, 12Vanderbilt University Medical Center, Nashville, TN, 13Hamburg Centre for Pediatric and Adolescent Rheumatology, Hamburg, Germany, 14Children’s Hospital of Georgia, Augusta University Medical Center, Augusta, GA, 15Bristol Myers Squibb, Princeton, NJ, 16Bristol Myers Squibb, Basking Ridge, NJ, 17Paediatric Rheumatology International Trials Organisation (PRINTO), Genoa, Italy, 18Cincinnati Children’s Hospital Medical Center, University of Cincinnati, Cincinnati, OH

    Background/Purpose: The ongoing phase 4 Pediatric Rheumatology Collaborative Study Group (PRCSG)/Paediatric Rheumatology INternational Trials Organisation (PRINTO) registry was designed to assess the long-term (up to…
  • Abstract Number: 0265 • ACR Convergence 2021

    Development and Preliminary Acceptability of JIActiv, a Social Media-Based Program Promoting Engagement in Physical Activity Among Young People Living with Juvenile Idiopathic Arthritis

    Sabrina Cavallo1, Karine Toupin April2, Ciaran Duffy2, Karina Cristea1, Jihene Tlili1, Imane Brahmi1, Zeinab Ahmadian1, Michele Gibbon3, Alexandra Sirois4, Laurie Proulx5, Sara Ahmed6, Claudine Auger1 and Jennifer Stinson7, 1Université de Montréal, Montréal, QC, Canada, 2University of Ottawa, Ottawa, ON, Canada, 3Children's Hospital of Eastern Ontario, Ottawa, ON, Canada, 4Canadian Arthritis patient Alliance, Montréal, QC, Canada, 5Canadian Arthritis Patient Alliance, Ottawa, ON, Canada, 6Children's Hospital of Eastern Ontario, Montréal, QC, Canada, 7The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Young people with juvenile idiopathic arthritis (JIA) are at greater risk for adopting chronic sedentary behaviours and not meeting national physical activity guidelines compared…
  • Abstract Number: 1927 • ACR Convergence 2021

    Heterogeneity of Juvenile Idiopathic Arthritis Synovial Fibroblasts Correlates to Disease Progression and Provides Compelling Diagnostic Data

    Megan Simonds1, Kathleen Sullivan2, Carlos Rose3 and AnneMarie Brescia4, 1Nemours, Wilmington, DE, 2The Children's Hospital of Philadelphia, Philadelphia, PA, 3Thomas Jefferson University/duPont Hospital for Children, Wilmington, DE, 4Nemours/A.I.duPont Hospital for Children, Wilmington, DE

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) induces growth disturbances in affected joints. Fibroblast-like synoviocytes (FLS) play a crucial role in JIA pathogenesis; however, the mechanisms by…
  • Abstract Number: 0248 • ACR Convergence 2021

    Proportion of Patients with a Polyphasic Disease Course in Systemic-onset Juvenile Idiopathic Arthritis May Be Higher in the Age of Cytokine Inhibitors

    Itay Marmor1, Rotem Semo Oz2, Amir Hendel3, Guy Hazan1, Kevin Baszis4, Anthony French1, Cuoghi Edens5, irit Tirosh6, Yonatan Butbul Aviel7, Liora Harel8 and Gil Amarilyo9, 1Washington University School of Medicine, St. Louis, MO, 2Sheba Medical Center, Herzelyia, Israel, 3Sackler Faculty of Medicine, Tel Aviv University; Clalit Health Services, Sharon and Shomron County, Tel Aviv, Israel, 4Washington University School of Medicine, St Louis, MO, 5University of Chicago, Chicago, IL, 6Sheba Medical Center, Ramat Gan, Israel, 7Rambam Medical center, Haifa, Israel, 8Scheiders Children Medical Center of Israel, Petah-Tiqva, Israel, 9Schneider Children's Medical Center of Israel, Kibbutz Maggal, Israel

    Background/Purpose: Systemic-onset juvenile idiopathic arthritis (sJIA) is a pediatric autoinflammatory condition, known for significant variability between patients in its severity and long-term outcomes. The classification…
  • Abstract Number: 0658 • ACR Convergence 2021

    ACCORD: A Novel Rheumatology Transition Clinic Structure for Adolescent and Young Adult Patients with Childhood Onset Rheumatic Disease

    Rebecca Overbury1, Kelly Huynh2, Tracy Frech1, John Bohnsack1 and Aimee Hersh1, 1University of Utah, Salt Lake City, UT, 2Intermountain Health Care, Salt Lake City, UT

    Background/Purpose: The transition of health care from Pediatric to Adult providers for adolescents and young adults with childhood onset rheumatic disease continues to be associated…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. Academic institutions, private organizations and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part a scientific presentation or presentation of additional new information that will be available at the time of the meeting) is under embargo until Saturday, November 11, 2023.

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