Abstract Number: 0577 • ACR Convergence 2021
Comorbidity Burden as Scored Using the Rheumatic Disease Comorbidity Index (RDCI) Is Associated with Varying Treatment Patterns in Patients with Inflammatory Arthritis – a Study Using the EHR-Derived Rheumatic and Arthritis Disease Information Registry (RADIR)
Background/Purpose: Higher comorbidity burden (CB) has been associated with treatment choices in RA, but not assessed in populations including multiple forms of inflammatory arthritis (IA)…Abstract Number: 0786 • ACR Convergence 2021
Diagnostic Utility of FibroScan in Screening for Liver Injury in Patients with Inflammatory Arthritis on Treatment with Methotrexate (MTX)
Background/Purpose: Methotrexate (MTX) is often the primary medication to treat various rheumatic diseases, including rheumatoid arthritis, psoriasic arthritis and many other inflammatory diseases. MTX is…Abstract Number: 1131 • ACR Convergence 2021
Interleukin 6 Concentration in Synovial Fluid and Its Clinical Significance
Background/Purpose: Inflammatory arthritis (IA) treated with disease modifying antirheumatic drugs lead to secondary osteoarthritis (OA) due to inflammation, aging, and other factors. Inflammatory arthritis can…Abstract Number: 1510 • ACR Convergence 2021
Joint CD8+ Tissue Resident Memory Cell Activation Produces Local Inflammatory Arthritis
Background/Purpose: Following infection, resident memory CD8+ T cells (TRM) populate tissues as long lived sentinel cells. Their aberrant activation can trigger relapsing inflammation in autoimmune…Abstract Number: 0045 • ACR Convergence 2021
Endothelial Cells from Patients with DMARD Naïve, Active Inflammatory Arthritis Demonstrate Pro-inflammatory Sensitisation That Is Reversed by Therapy Initiation
Background/Purpose: Inflammatory arthritides (IA) including rheumatoid arthritis are associated with increased cardiovascular disease (CVD) mortality. Although inflammation-driven endothelial dysfunction is considered a major factor, the…Abstract Number: 483 • ACR/ARP Annual Meeting 2019
Can a Single Question on Functional Impairments Facilitate the Diagnosis of Early Inflammatory Arthritis? A Cross-Sectional Derivation and Validation Study in Two Early Arthritis Recognition Clinics
Background/Purpose: Early treatment initiation in RA is associated with improved outcomes but requires early identification of synovitis. Joint swelling in early inflammatory arthritis (IA) may…Abstract Number: 997 • ACR/ARP Annual Meeting 2019
Stromal Cell-derived DCSTAMP Coordinates Cell Migration and Osteoclast Activation in TNF-driven Murine Arthritis
Background/Purpose: DC-STAMP is a transmembrane protein involved in the fusion of mononuclear osteoclasts and essential for the formation of fully functional multinucleated osteoclasts (OCs). Recently…Abstract Number: 1360 • ACR/ARP Annual Meeting 2019
Ultrasound Guided Synovial Biopsies Safely Aid in the Assessment of Inflammatory Arthritis
Background/Purpose: Synovial biopsies have an important role in the diagnostic evaluation of patients with undifferentiated inflammatory arthritis (UIA) whose clinical examination and blood and synovial…Abstract Number: 1363 • ACR/ARP Annual Meeting 2019
Longitudinal Work Transitions in Early Inflammatory Arthritis Patients: Are There Targets for Intervention to Improve Employment?
Background/Purpose: Historically, increasing proportions of patients with rheumatoid arthritis stop working on long-term follow-up, often due to arthritis. The trajectory of work transitions in early…Abstract Number: 2823 • ACR/ARP Annual Meeting 2019
Progression to Inflammatory Arthritis After Screening Autoantibody Positive in a Non-Clinical Setting
Background/Purpose: Rheumatoid arthritis (RA)-related autoantibodies are typically elevated prior to the onset of seropositive RA. Screening for autoantibody (aAb) positive individuals is a means to…Abstract Number: 1806 • ACR/ARP Annual Meeting 2019
Inflammatory Arthritis Induced by Immune Checkpoint Inhibitor Therapy: A Distinct Clinical Entity and Immunologic Phenotype
Background/Purpose: Immune checkpoint inhibitors (ICIs) are being used in the treatment of a variety of malignancies. ICIs target cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4), programmed cell-death…Abstract Number: 1842 • ACR/ARP Annual Meeting 2019
Patients and Relatives Coping with Inflammatory Arthritis: Impact of Communication, Social Support and Relatives Burden on Patients Perceived Health
Background/Purpose: Relatives’ and patients’ adjustment to a chronic disease is complex, and there is room for improvement in the support provided to the dyad. So…Abstract Number: 1901 • ACR/ARP Annual Meeting 2019
Serious Infections in Offspring Exposed in Utero to Non-TNFi Biologics and Tofacitinib
Background/Purpose: During pregnancy, maternal circulating immunoglobulins G (IgG) are actively transported across the placenta through their Fc portion. Thus, TNFi and other biologics harbouring an Fc…Abstract Number: 2264 • ACR/ARP Annual Meeting 2019
Prescribing Exercise: Facilitators and Barriers to the Successful Implementation of Physical Activity Guidelines in Inflammatory Arthritis
Background/Purpose: Physical Activity (PA) is beneficial for people with inflammatory arthritis (IA). In 2018, EULAR published the first recommendations for guiding PA in patients with…Abstract Number: 2273 • ACR/ARP Annual Meeting 2019
Risk of Serious Infections in Offspring According to TNFi Subtypes
Background/Purpose: TNFi subtypes have differential placental transfer, with some reaching higher fetal than maternal blood levels. Thus, certain TNFi subtypes could cause immunosuppression in the offspring.…
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