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Abstracts tagged "Infection"

  • Abstract Number: 0456 • ACR Convergence 2020

    Reduced Risk of Serious Pneumococcal Infection up to 10 Years After Immunization with 7-valent Conjugated Pneumococcal Vaccine in Patients with Inflammatory Arthritis

    Johanna Nagel1, Göran Jönsson2, Jan Åke Nilsson3, Chanchai Manuswin4, Martin Englund5, Tore Saxne1, Pierre Geborek1 and Meliha Kapetanovic1, 1Lund University, Skåne University Hospital, Department of Clinical Sciences Lund, Rheumatology, Lund, Sweden, Lund, Sweden, 2Lund University, Skåne University Hospital, Department of Clinical Sciences Lund, Infection Medicine, Lund, Sweden, Lund, Sweden, 3Rheumatology, Department of Clinical Sciences, Malmö, Lund University. Department of Rheumatology, Skåne University Hospital, Malmö and Lund, Sweden, Malmö, Sweden, 4Centre of Registers South, Skåne University Hospital, Lund, Sweden, Lund, Sweden, 5Lund University, Lund, Sweden

    Background/Purpose: The aim was to examine the rates of putative pneumococcal infections up to 10 years before and after administration of heptavalent conjugated pneumococcal vaccine…
  • Abstract Number: 0776 • ACR Convergence 2020

    The Influence of Adipokine Profile and Periodontal Infection in Early Stages of Rheumatoid Arthritis and First-degree Relatives

    Consuelo Romero-Sanchez1, Juliette De Avila2, Jeimmy Andrea Chaparro-Sanabria3, Philipe Chalem Choueka4, Juan Manuel Bello-Gualtero5, Alejandro Ramos-Casallas2, Lorena Chila-M2 and Wilson Bautista-Molano6, 1Hospital Militar Central, Rheumatology and Immunology Department, Universidad Militar Nueva Granada / Clinical Immunology Group, Hospital Militar Central, School of Medicine, Universidad Militar Nueva Granada /Universidad El Bosque, Cellular and Molecular Immunology Group -InmuBo-, School of Dentistry, Bogotá D.C., Colombia, 2Universidad El Bosque, Cellular and Molecular Immunology Group -InmuBo-, School of Dentistry, Bogotá D.C., Colombia, 3Clinical Immunology Group, Hospital Militar Central, School of Medicine, Universidad Militar Nueva Granada, Bogotá D.C., Colombia, 4Fundacion Instituto de Reumatología Fernando Chalem, Universidad El Rosario, Bogotá D.C., Colombia, 5Hospital Militar Central, Rheumatology and Immunology Department, Universidad Militar Nueva Granada/ Clinical Immunology Group, Hospital Militar Central, School of Medicine, Universidad Militar Nueva Granada, Bogotá D.C., Colombia, 6University Hospital Fundación Santa Fé de Bogotá and Universidad El Bosque, Bogotá, Colombia

    Background/Purpose: Early RA (eRA) patients have a significant incidence of periodontal inflammation and overweight/obesity. A similar degree of disease activity, functional disability and health-related quality…
  • Abstract Number: 1694 • ACR Convergence 2020

    Risk Factors Associated with Pneumocystis Jirovecii Pneumonia in Juvenile Myositis in North America

    Sara Sabbagh1, Jessica Neely2, Albert Chow3, Marietta DeGuzman4, Jamie Lai5, Svetlana Lvovich6, Tara McGrath7, Maria Pereira8, Iago Pinal-Fernandez9, Jordan Roberts10, Kelly Rouster-Stevens11, Heinrike Schmeling12, Anjali Sura13, Gabriel Tarshish14, Lori Tucker15, Lisa G. Rider16 and Susan Kim17, 1Medical College of Wisconsin, Fox Point, WI, 2UCSF, San Francisco, CA, 3Loma Linda University, San Bernardino, CA, 4Baylor College of Medicine, Houston, 5University of Colorado, The Woodlands, TX, 6St Christopher's Hospital for Children, Philadelphia, PA, 7University of British Columbia, Vancouver, BC, Canada, 8Baylor College of Medicine, Houston, TX, 9National Institutes of Health, Bethesda, MD, 10Boston Children's Hospital, Boston, MA, 11Emory University/Children's Healthcare of Atlanta, Atlanta, GA, 12University of Calgary, Calgary, AB, Canada, 13Upstate University Hospital, Syracuse, NY, 14Children's Hospital at Montefiore, New York, NY, 15BC Children's Hospital, Vancouver, BC, Canada, 16Environmental Autoimmunity Group, Clinical Research Branch, NIEHS, NIH, Garrett Park, MD, 17UCSF Benioff Children's Hospital, San Francisco, CA

    Background/Purpose: Pneumocystis jirovecii pneumonia (PJP) is associated with significant morbidity and mortality in adult myositis patients; however, few studies have examined PJP in juvenile myositis…
  • Abstract Number: 0005 • ACR Convergence 2020

    Geographical Variations in COVID-19 Perceptions and Patient Management: A National Survey of Rheumatologists

    Bella Mehta1, Deanna Jannat-Khah2, Carol Mancuso3, Anne Bass1, Carine Moezinia4, Allan Gibofsky3, Susan Goodman5 and Said Ibrahim6, 1Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 2Hospital for Special Surgery, New York City, NY, 3Hospital for Special Surgery, New York City, 4Hospital for Special Surgery, New York, 5Hospital for Special Surgery, Weill Cornell Medicine, New York, NY, 6Weill Cornell Medicine, Cleveland, OH

    Background/Purpose: To investigate the perceptions and behaviors of rheumatologists in the United States (US) regarding the risk of COVID-19 for their autoimmune patients and the…
  • Abstract Number: 0520 • ACR Convergence 2020

    Antiphospholipid Antibodies and Thrombotic Events in COVID-19 Patients Hospitalized in Medicine Ward

    Alexandre Le Joncour1, Corinne Frere1, Isabelle Martin-Toutain1, Paul Gougis1, Pascale Ghillani-Dalbin1, Georgina Maalouf1, Matheus Vieira1, Anne-Genevieve Marcelin1, Joe-Elie Salem1, Yves Allenbach2, David Saadoun3, Olivier Benveniste4 and Patrice Cacoub1, 1APHP, paris, France, 2Sorbonne Université, Paris, Ile-de-France, France, 3AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Department of Internal Medicine and Clinical Immunology, F-75013, Paris, France, Centre national de références Maladies Autoimmunes et systémiques rares et Maladies Autoinflammatoires rares, PAris, France, 4Sorbonne Université, paris, France

    Background/Purpose: A high prevalence of thrombotic events has been reported in critically ill COVID-19 patients but data on the prevalence of thrombosis in ward patients…
  • Abstract Number: 0914 • ACR Convergence 2020

    Serious Infections in People with Systemic Sclerosis: A National U.S. Study

    Jasvinder Singh1 and John Cleveland1, 1University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: To study incidence, time-trends and outcomes of serious infections in systemic sclerosis (SSc).Methods: We used the 1998-2016 U.S. National Inpatient Sample data. We examined…
  • Abstract Number: 1758 • ACR Convergence 2020

    Prevalence and Incidence of Infection and Venous Thromboembolism in Rheumatoid Arthritis Patients Newly Initiating Various DMARD Classes: Real-World Analysis of 2012–2016 US Medicare Data

    Robin Dore1, Jenya Antonova2, Lawrence Chang2, Suying Li3, Haifeng Guo3, Yuanyuan Ji3 and Mark Genovese4, 1Private practice, Tustin, CA, 2Gilead Sciences, Foster City, CA, 3Chronic Disease Research Group, Minneapolis, MN, 4Stanford University Medical Center, Palo Alto, CA

    Background/Purpose: RA patients have an increased risk of infection1 and venous thromboembolism (VTE)2. Although rates of serious infection and VTE have been reported for Medicare…
  • Abstract Number: 0014 • ACR Convergence 2020

    Does the Type of Rheumatic Disease or Biologic Treatment Increase the Risk of Developing Severe COVID-19?

    Fernando López-Gutierrez1, Antía García-Fernández1, Jesús Loarce-Martos1, Laura Calvo-Sanz1, Ivan Del Bosque-Granero2, Veronica Garcia2, Boris Blanco-Cáceres1, Cristina Pijoan-Moratalla1, Lourdes Villalobos-Sánchez3, Javier Bachiller-Corral1 and Mónica Vázquez1, 1Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain, 2Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Madrid, Spain, 3Rheumatology, Hospital Universitario Ramón y Cajal, Madrid

    Background/Purpose: Patients with inflammatory rheumatic diseases (IRD) have an increased risk for infection related to immunosuppression secondary to their disease, treatment and comorbidities. Nonetheless recent…
  • Abstract Number: 0545 • ACR Convergence 2020

    The Use of Tocilizumab and Tofacitinib in Patients with Resolved Hepatitis B Infection: A Case Series

    Naomi Serling-Boyd1, Amir Mohareb2, Arthur Kim2, Emily Hyle2 and Zachary Wallace3, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Boston, 3Massachusetts General Hospital, Newton, MA

    Background/Purpose: The use of immunosuppressive medications in patients with a history of hepatitis B virus (HBV) infection is associated with an increased risk of HBV…
  • Abstract Number: 1004 • ACR Convergence 2020

    The Incidence, Mortality, and Economic Burden of Potentially Preventable Infections in Rheumatoid Arthritis Patients

    Soumyasri Kambhatla1, Estefania Gauto-Mariotti2 and Augustine Manadan3, 1John H Stroger Hospital of Cook County, Riverside, IL, 2John H. Stroger Jr. Hospital of Cook County, Chicago, IL, 3Rush University Medical Center, Chicago, IL

    Background/Purpose: Streptococcus pneumoniae, Herpes zoster, and influenza infections are common and potentially preventable causes of morbidity and mortality. Vaccinations have been shown to reduce infection…
  • Abstract Number: 1830 • ACR Convergence 2020

    Adverse Drug Reactions to Trimethoprim-sulfamethoxazole as a Prophylactic Agent Against Pneumocystis Pneumonia in Patients with Systemic Lupus Erythematosus: anti-Sm Antibody as a Possible Risk Factor

    Shinji Izuka1, Hiroyuki Yamashita2, Yuko Takahashi2 and Hiroshi Kaneko2, 1Devision of Rheumatic Disease, National Center for Global Health and Medicine, Toshima-Ku, Tokyo, Japan, 2Devision of Rheumatic Disease, National Center for Global Health and Medicine, Shinjuku, Tokyo, Japan

    Background/Purpose: Pneumocystis pneumonia (PCP) is a life-threatening infection in immunocompromised patients, including those with connective tissue diseases (CTDs), treated with corticosteroids or immunosuppressive agents. Trimethoprim-sulfamethoxazole…
  • Abstract Number: 0016 • ACR Convergence 2020

    Differential Characteristics in Inflammatory Rheumatologic Patients with Severe and Mild COVID-19 Infection

    Paula García Escudero1, Claudia Stoye2, Orlando Pompei fernández2, Marta González Fernández1, Joaquín María Belzunegui Otano3, Juan Ramón De Dios2, Belén Álvarez Rodríguez2, Elena Garmendia Sánchez1, Susana Gil2, Ana Ruibal-Escribano4, Margarida Vasques Rocha2, Francisco García Llorente5, César Antonio Egües6, Edurne Guerrero7 and Jaime Calvo-Alén2, 1Hospital Universitario Cruces, Barakaldo, Spain, 2Hospital Universitario Araba, Vitoria-Gasteiz, Pais Vasco, Spain, 3Rheumatology Service, Hospital Universitario Donostia. San Sebastián, Spain, San Sebastian, Spain, 4Hospital Alfredo Espinosa, Urduliz, Pais Vasco, Spain, 5Hospital Universitario de Galdakao, Galdakao, Pais Vasco, Spain, 6Hospital Universitario Donostia, Donostia-San Sebastián, Pais Vasco, Spain, 7Hospital Alto Deba, Arrasate, Pais Vasco, Spain

    Background/Purpose: SARS COV 2 pandemic has been an issue which has challenged the health care systems around the world. Rheumatology has been involved in two…
  • Abstract Number: 0554 • ACR Convergence 2020

    Increased Burden of Painful Arthritis and Rheumatism Following the Chikungunya Epidemic 2006: India Rural Population Survey 2018

    Arvind Chopra1, Ravi Ghorpade2, Anuradha Venugopalan1, Manjit Saluja1 and Kiran Adam1, 1Center for Rheumatic Diseases, Pune, India, 2Center for Rheumatic Diseases, Pune

    Background/Purpose: A spectrum of post Chikungunya (Chik) arthritis , often RA like, were referred to an urban rheumatology centre (Pune India)during the 2006 epidemic (Arthritis…
  • Abstract Number: 1010 • ACR Convergence 2020

    Infection and Malignancy Outcomes in Patients with RA Treated with Abatacept: Results from a Multinational Surveillance Study

    Alyssa Dominique1, Merete Hetland2, Axel Finckh3, Jacques-Eric Gottenberg4, Florenzo Iannone5, Roberto Caporali6, Dan Nordstrom7, M Victoria Hernandez8, Carlos Sanchez-Piedra9, Fernando Sanchez-Alonso9, Karel Pavelka10, Zlatuše Křístková11 and Teresa Simon12, 1Bristol-Myers Squibb Company, Princeton, NJ, 2The DANBIO Registry, Rigshospitalet, Glostrup, Denmark, 3Division of Rheumatology, University Hospitals of Geneva, Geneva, Switzerland, 4Strasbourg University Hospital, Strasbourg, France, 5DETO-Rheumatology Unit, University of Bari, Bari, Italy, 6Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy, 7Helsinki University Hospital and Helsinki University, Helsinki, Finland, 8Rheumatology Department, Hospital Clinic of Barcelona, Barcelona, Spain, 9Biobadaser, Research Unit, Sociedad Española de Reumatología, Madrid, Spain, 10Institute of Rheumatology and Department of Rheumatology, First Faculty of Medicine, Charles University, Prague, Czech Republic, 11Institute of Biostatistics and Analyses, Ltd., Brno, Czech Republic, 12Bristol-Myers Squibb Company (at time of analysis), Princeton, NJ

    Background/Purpose: Compared with the general population, patients with RA are at an increased risk of infection and certain malignancies, which may be increased further with…
  • Abstract Number: 1835 • ACR Convergence 2020

    Evaluation of Low Dose Glucocorticoid Effects on Infection Occurrence in Systemic Lupus Erythematosus Patients

    Kazuya Abe1, Nobuyuki Yajima2, Yuichi Ishikawa3, Yasuhiko Kita4, Ken-ei Sada5, Ryusuke Yoshimi6, Yasuhiro Shimojima7, Shigeru Ohno8, Hiroshi Kajiyama9, Kunihiro Ichinose10, Shuzo Sato11 and Michio Fujiwara12, 1Department of Rheumatology, Yokohama Rosai Hospital, Chiba, Japan, 2Division of Rheumatology, Department of Internal Medicine, Showa University School of Medicine, Tokyo, Japan, 3Department of Rheumatology, Yokohama Rosai Hospital, Tokyo, Japan, 4Department of Rheumatology, Yokohama Rosai Hospital, kanagawa, 5Department of Nephrology, Rheumatology, Endocrinology and Metabolism, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Science, Okayama, Japan, 6Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 7Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Matsumoto, Japan, 8Center for Rheumatic Diseases, Yokohama City University Medical Center, Yokohama, Japan, 9Department of Rheumatology and Applied Immunology Faculty of Medicine, Saitama Medical University, Iruma-gun, Saitama, Japan, 10Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, 11Fukushima Medical University School of Medicine, Department of Rheumatology, Fukushima, Japan, 12Department of Rheumatology, Yokohama Rosai Hospital, Kanagawa, Japan

    Background/Purpose: Infection is major cause of morbidity and mortality in systemic lupus erythematosus (SLE) patient. The past exploratory study suggested various infection risk in SLE…
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