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Abstracts tagged "histopathologic"

  • Abstract Number: 1035 • 2018 ACR/ARHP Annual Meeting

    Different Cartilage-Bone Unit in Patients with Primary Osteoarthritis and Secondary Osteoarthritis Caused By Rheumatoid Arthritis

    Rasmus Klose-Jensen1, Anne Friesgaard Christensen2, Kresten Krarup Keller3 and Ellen-Margrethe Hauge3,4, 1Department of Rheumatology, Aarhus University Hospital, Aarhus, Aarhus C, Denmark, 2Department of Internal Medicine, Lillebaelt Hospital, Vejle, Vejle, Denmark, 3Department of Rheumatology, Aarhus University Hospital, Aarhus, Aarhus, Denmark, 4Clinical medicine, Department of Clinical Medicine, Aarhus University Hospital, Århus N, Denmark

    Background/Purpose: Despite distinct aetiologies of joint diseases, the osteoarthritic end-stage of primary osteoarthritis (OA) and rheumatoid arthritis (RA) are described using similar radiological features. However,…
  • Abstract Number: 1462 • 2018 ACR/ARHP Annual Meeting

    Fibrin Deposition and Neutrophil Infiltration of Rheumatoid Arthritis Synovium Are Associated with Duration of Morning Stiffness

    Dana Orange1, Caroline Jiang1, Edward F. DiCarlo2, Tania Pannellini3, Laura T. Donlin4, Serene Z. Mirza5, Mark P. Figgie6, Vivian P. Bykerk7, Ana-Maria Orbai8, Sarah Mackie9 and Susan M. Goodman3, 1Rockefeller University, New York, NY, 2Laboratory Medicine, Hospital for Special Surgery, New York, NY, 3Hospital for Special Surgery, New York, NY, 4Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY, 5Rheumatology, Hospital for Special Surgery, New York, NY, 6Surgery, Hospital for Special Surgery, New York, NY, 7Deptartment of Rheumatology, Hospital for Special Surgery, New York, NY, 8Johns Hopkins University School of Medicine, Baltimore, MD, 9NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, University of Leeds, Leeds, United Kingdom

    Background/Purpose: Stiffness is a hallmark of RA, but little is known about the etiology. We investigated stiffness association with RA disease activity and determined whether…
  • Abstract Number: 1470 • 2018 ACR/ARHP Annual Meeting

    Russell Bodies and Serological Status in Rheumatoid Arthritis

    Michael A. McNamara1, Susan M. Goodman2, Laura T. Donlin3, Dana Orange4, Serene Z. Mirza1, Jackie Szymonifka2, Mark P. Figgie5, Vivian P. Bykerk2 and Edward F. DiCarlo6, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Hospital for Special Surgery, New York, NY, 3Arthritis and Tissue Degeneration Program and the David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY, 4Rockefeller University, New York, NY, 5Surgery, Hospital for Special Surgery, New York, NY, 6Laboratory Medicine, Hospital for Special Surgery, New York, NY

    Russell Bodies and Serological Status in Rheumatoid Arthritis Background/Purpose: Russell bodies (RBs) are globular aggregates of immunoglobulin produced by plasma cells and identified both within…
  • Abstract Number: 1719 • 2018 ACR/ARHP Annual Meeting

    High-Throughput Quantitative Histology in Systemic Sclerosis Skin Disease Using Computer Vision

    Chase Correia1, Seamus Mawe2, Mary A. Carns3, Kathleen Aren3, Aileen Hoffman4, Monique Hinchcliff5 and J. Matthew Mahoney6, 1Northwestern University, Chicago, IL, 2Department of Neurological Sciences, University of Vermont Larner College of Medicine, Burlington, VT, 3Northwestern University, Feinberg School of Medicine Scleroderma Program, Chicago, IL, 4Northwestern Feinberg School of Medicine, Chicago, IL, 5Rheumatology, Northwestern University, Chicago, IL, 6Neurological Sciences, University of Vermont College of Medicine, Burlington, VT

    Background/Purpose: The lack of a reproducible and quantitative method to accurately assess histological skin fibrosis in patients with systemic sclerosis (SSc) has long plagued clinical…
  • Abstract Number: 2907 • 2018 ACR/ARHP Annual Meeting

    Comparison of the Joints Ultrasonography in the Patients with Rheumatoid Arthritis Treated By Biological Agents and the Corresponding Synovial Histological Findings

    Asami Abe1, Hajime Ishikawa2 and Kunihiko Wakaki3, 1Rheumatology, Niigata Rheumatic Center, Shibata, Japan, 2Department of Rheumatology, Niigata Rheumatic Center, Shibata, Japan, 3Pathology, Niigata Prefectural Shibata Hospital, Shibata, Japan

    Comparison of the joints ultrasonography in the patients with rheumatoid arthritis treated by biological agents and the corresponding synovial histological findings Background/Purpose: In the treatment…
  • Abstract Number: 2972 • 2018 ACR/ARHP Annual Meeting

    Multicentric Reticulohistiocytosis (1980-2017): A Rare Disease, Commonly Associated with Malignancy and Autoimmunity

    Avneek Singh Sandhu1, Cynthia S. Crowson2, David Wetter3, Gavin McKenzie4 and Ashima Makol1, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic College of Medicine and Science, Rochester, MN, 3Dermatology, Mayo Clinic, Rochester, MN, 4Radiology, Mayo Clinic, Rochester, MN

    Background/Purpose: Multicentric reticulohistiocytosis (MRH) is a systemic disease characterized by papulo-nodular skin eruptions and progressive, deforming arthritis. We aimed to examine the clinical correlates and…
  • Abstract Number: 567 • 2017 ACR/ARHP Annual Meeting

    Minor Salivary Gland Histopathology, Major Salivary Gland Ultrasonography, and Secretory Function in Smoking Patients with Primary Sjögren’s Syndrome

    Daniel S. Hammenfors1, Haris Causevic2, Johan G. Brun3, Roland Jonsson1 and Malin V. Jonsson4, 1Department of Rheumatology, Haukeland University Hospital, University of Bergen, Bergen, Norway, 2Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, 3Department of Rheumatology, Haukeland University Hospital, Bergen, Bergen, Norway, 4Department of Clinical Dentistry, Section for Oral and Maxillofacial Radiology, University of Bergen, Bergen, Norway

    Background/Purpose: Several studies have reported a protective effect of smoking with regard to risk for primary Sjögren’s syndrome (pSS) and minor salivary gland inflammation. To…
  • Abstract Number: 1347 • 2017 ACR/ARHP Annual Meeting

    Ultrasonography and Synovial Histology in the RA Patients in Remission

    Asami Abe1, Hajime Ishikawa2 and Kunihiko Wakaki3, 1Rheumatplogy, Niigata Rheumatic Center, Shibata, Japan, 2Department of Rheumatology, Niigata Rheumatic Center, Shibata, Japan, 3Pathology, Niigata Prefectural Shibata Hospital, Shibata, Japan

    Background/Purpose: In the treatment of rheumatoid arthritis (RA), the early diagnosis and early medical treatment via tight control have become increasingly important with the advent…
  • Abstract Number: 2114 • 2017 ACR/ARHP Annual Meeting

    Interstitial Pneumonia with Autoimmune Features (IPAF): Are There Definable Subsets?

    Sepehr Mesdaghinia1, Julio Arturo Huapaya2, Brainerd Ewarien2 and Virginia D. Steen1, 1Rheumatology, MedStar Georgetown University Hospital, Washington, DC, 2Medicine, MedStar Georgetown University Hospital, Washington, DC

    -       Background/Purpose: Interstitial lung disease (ILD) can be an early manifestation of an occult connective tissue disease (CTD).  It is important to separate these patients…
  • Abstract Number: 2416 • 2017 ACR/ARHP Annual Meeting

    Histopathological Change Caused By Biological Treatment in Rheumatoid Arthritis Synovial Tissue

    Ayako Kubota, Toru Suguro, Masayuki Sekiguchi and Kazuaki Tsuchiya, Toho University Omori Medical Center, Tokyo, Japan

    Background/Purpose: Multiple studies addressing the effects of biologics on the synovial tissue in rheumatoid arthritis (RA) patients have been reported. There are, however, few studies…
  • Abstract Number: 2136 • 2016 ACR/ARHP Annual Meeting

    CD14 Deficiency Delays Progression of Cartilage Degeneration and Protects Against Early Deficits in Functional Outcomes in a Murine Osteoarthritis Model

    Nisha Sambamurthy1,2, Vu Nguyen1,2, Ryan Smalley2,3, George R. Dodge3,4 and Carla R. Scanzello1,2,3, 1Division of Rheumatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 2Translational Musculoskeletal Research Center, CMC Veterans Affairs Medical Center, Philadelphia, PA, 3Department of Orthopedic Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 4Research, CMC Veterans Affairs Medical Center, Philadelphia, PA

    Background/Purpose: CD14, though expressed by multiple cell types, is highly expressed by monocytes and macrophages. It forms a complex with Toll-like receptors (TLRs), particularly TLR-2…
  • Abstract Number: 2138 • 2016 ACR/ARHP Annual Meeting

    Transcriptional Analysis of Synovial Tissue Reveals Sustained Inflammatory Chemokine Expression Despite Minimal Histopathologic Change in the Destabilization of Medial Meniscus Model of Murine Knee Osteoarthritis

    Nisha Sambamurthy1,2, Vu Nguyen1,2, Jason G. Lieberthal3, George R. Dodge4,5 and Carla R. Scanzello1,2,5, 1Division of Rheumatology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 2Translational Musculoskeletal Research Center, CMC Veterans Affairs Medical Center, Philadelphia, PA, 3Internal Medicine, Mount Auburn Hospital, Cambridge, MA, 4Research, CMC Veterans Affairs Medical Center, Philadelphia, PA, 5Department of Orthopedic Surgery, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA

    Background/Purpose: The destabilization of medial meniscus (DMM) model of instability-induced OA replicates disease-related tissue pathology (including cartilage erosion, osteophytosis) and pain-related joint dysfunction, making it…
  • Abstract Number: 2355 • 2016 ACR/ARHP Annual Meeting

    Histology of Bone Marrow Lesions in Osteoarthritis: A Systematic Literature Review

    S. van Beest1, F.P.B. Kroon1, W. Damman1, J.W. Schoones2, A. Ioan-Facsinay1 and M. Kloppenburg3, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Walaeus Library, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Bone marrow lesions (BMLs) are of high interest in osteoarthritis for their association with pain and structural progression. They are characterized on magnetic resonance…
  • Abstract Number: 2838 • 2016 ACR/ARHP Annual Meeting

    Histopatholgic Predictors of Poor Renal Outcomes in a Multi-Ethnic Cohort

    Stacy Tanner1, Dominick Santoriello2, Shanthi Dhaduvai3, Thania Perez4, Anca D. Askanase5 and Laura Geraldino-Pardilla6, 1Division of Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 2Renal Pathology, Columbia University College of Physicians & Surgeons, New York, NY, 3Rheumatology, Carilion Clinic, Roanoke, VA, 4Columbia University College of Physicians & Surgeons, New York, NY, 5Department of Medicine, Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, 6Columbia University College of Physicians & Surgeons, new york, NY

    Background/Purpose: Lupus nephritis (LN) remains an important cause of morbidity and mortality in patients with SLE.  Tubular atrophy and interstitial fibrosis on initial renal biopsies…
  • Abstract Number: 142 • 2016 ACR/ARHP Annual Meeting

    Quality Assessment of Ultrasound Guided Synovial Biopsies Performed in Clinical Practice

    Aurélie Najm1, Marie-Françoise Heymann2, Géraldine Bart1, Yves Maugars1 and Benoît Le Goff1, 1Rheumatology, Nantes University Hospital, Nantes, France, 2Histopathology, Histopathology, Nantes University Hospital, Nantes, France

    Background/Purpose: Synovial tissue is the principal target and end organ involved in the pathogenesis of multiple articular disease processes. Histological and bacteriological analyses of synovial…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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