Abstracts tagged "giant cell arteritis"

Abstract Number: 2684 • 2019 ACR/ARP Annual Meeting
Real-world Comparative Study of Methotrexate vs Tocilizumab in Patients with Giant Cell Arteritis with Large Vessel Involvement
DIANA PRIETO- PENA¹, Mónica Calderón-Goercke ², Javier Loricera ³, Javier Narváez ⁴, Elena Aurrecoechea ⁵, Ignacio Villa ⁶, Santos Castañeda ⁷, Catalina Gómez-Arango ⁸, Antonio Mera ⁹, Eva Perez Pampín ⁹, Vicente Aldasoro Caceres ¹⁰, N Alvarez Rivas ¹¹, N Fernandez Llanio ¹², María Álvarez del buergo ¹³, Luisa Marena-Rojas ¹⁴, Francisca Sivera ¹⁵, Eva Galindez-Agirregoikoa ¹⁶, Roser Solans-Laqué ¹⁷, Susana Romero-Yuste ¹⁸, Lara Sanchez-Bilbao ¹⁹, Iñigo Gonzalez-Mazon ¹, Isabel Martínez Rodríguez ²⁰, Ignacio Banzo ²⁰, Miguel Angel González-Gay ²¹ and Ricardo Blanco ¹⁹, ¹Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ²Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ³Rheumatology Department. Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ⁴Rheumatology Department, Hospital Universitario de Bellvitge, Barcelona, Spain, Barcelona, Catalonia, Spain, ⁵Rheumatology Department. Hospital Sierrallana, Torrelavega, Spain, ⁶Hospital de Sierrallana, Torrelavega, Cantabria, Spain, ⁷Rheumatology Department, Hospital Universitario de la Princesa, IIS-Princesa, Madrid, Spain, Madrid, Spain, ⁸Hospital Alto Deba, Mondragon, Pais Vasco, Spain, ⁹Division of Rheumatology, Instituto de Investigación Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain, Santiago de Compostela, Spain, ¹⁰Complejo Hospitalario de Navarra, Navarra, Navarra, Spain, ¹¹H. Lucus Augusti, Lugo, Spain, ¹²H. Arnau de Vilanova, Lerida, Spain, ¹³Hospital Río Carrión, Palencia, Castilla y Leon, Spain, ¹⁴Hospital La Mancha Centro, Alcázar de San Juan, Castilla-La Mancha, Spain, ¹⁵Hospital General Universitario de Elda, Elda, Spain, ¹⁶Hospital de Basurto, Bilbao, Pais Vasco, Spain, ¹⁷Department of Internal Medicine, Hospital Vall d'Hebron, Barcelona, Spain., Barcelona, Catalonia, Spain, ¹⁸Complejo Hospitalario Universitario Pontevedra, Pontevedra, Galicia, Spain, ¹⁹Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, ²⁰Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²¹Universidad de Cantabria and IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain
Background/Purpose: Giant cell arteritis (GCA) is the most common large vasculitis in elderly patients. According to previous studies, 50% of patients with GCA in whom…
Abstract Number: 767 • 2019 ACR/ARP Annual Meeting
Outcome Measures in Large-Vessel Vasculitis: Relationships Between Patient, Physician, Imaging, and Laboratory-Based Domains
Casey A. Rimland¹, Kaitlin Quinn ², Joel S. Rosenblum ³, Mollie Schwartz ⁴, K Bates Gribbons ⁵, Elaine Novakovich ⁶, Antoine Sreih ⁷, Peter Merkel ⁷, Mark A. Ahlman ⁸ and Peter C. Grayson ⁹, ¹National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, Chapel Hill, NC, ²Georgetown University Hospital/National Institutes of Health, Washington, DC, ³National Institute of Arthritis, Musculoskeletal and Skin Disease (NIAMS), Bethesda, MD, Bethesda, MD, ⁴University of Maryland, Baltimore, MD, ⁵National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ⁶National Institutes of Health, Bethesda, MD, ⁷University of Pennsylvania, Philadelphia, PA, ⁸Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, Bethesda, MD, ⁹National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: Large-vessel vasculitis (LVV) is characterized by inflammation of the aorta and its major branches. The most common forms of LVV include giant cell arteritis…
Abstract Number: 2660 • 2019 ACR/ARP Annual Meeting
Rationalizing the Use of MRI of the Scalp Arteries in the Diagnosis of Giant Cell Arteritis Through Multivariable Predictive Modelling
Mats Junek¹, Angela Hu ², Karen Beattie ³, Kimberly Legault ³, Stephanie Garner ⁴, Ryan Rebello ³ and Nader A. Khalidi ³, ¹McMaster University, Oakville, ²University of Toronto, Toronto, ON, Canada, ³McMaster University, Hamilton, ON, Canada, ⁴McMaster University, Hamilton, Canada
Background/Purpose: It has been historically difficult to develop effective diagnostic strategies and criteria in giant cell arteritis (GCA). While temporal artery biopsy was previously thought…
Abstract Number: 2685 • 2019 ACR/ARP Annual Meeting
Factors Contributing to Capturing Positive Findings on Temporal Artery Biopsy: An Australian Experience from Two Rheumatology Referral Centers
Victor Yang ¹, Benjamin Sutu ², Christopher McMaster ³, Claire Owen ¹, Alexander Strathmore ⁴, Gene-Siew Ngian ², Shereen Oon ⁴, Jessica Leung ¹, Ian Wicks ⁵, Russell Buchanan ¹ and David Liew¹, ¹Austin Health, Heidelberg, Victoria, Australia, ²Melbourne Health, Parkville, Victoria, Australia, ³Austin Health, Melbourne, Victoria, Australia, ⁴Melbourne Health, Melbourne, Victoria, Australia, ⁵Melbourne Health, Parkville, Australia
Background/Purpose: Temporal artery biopsy (TAB) is widely recognised as the diagnostic gold standard for GCA, despite having a poor sensitivity due to the presence of…
Abstract Number: 1210 • 2019 ACR/ARP Annual Meeting
Utilization of a Multispecialty Team for the Diagnosis of Giant Cell Arteritis Reduces Patient Morbidity
Arash Hassantoufighi ¹, Rachel Lu-Do¹, Mamta Sherchan ¹, Christopher Collins ¹, Joshpaul Dhillon ² and Florina Constantinescu ¹, ¹MedStar Washington Hospital Center, Department of Rheumatology, Washington, DC, ²MedStar Washington Hospital Center, Department of Internal Medicine, Washington, DC
Background/Purpose: Giant Cell Arteritis (GCA) is an autoimmune vasculitis, most common in older adults with a peak incidence in the seventh decade. The diagnosis is…
Abstract Number: 2661 • 2019 ACR/ARP Annual Meeting
A Ten-Year Retrospective Review of Temporal Artery Biopsy Lengths in Alberta
Raymond Chu¹, Caylea Foster ², Mohsin Ali ³, Todd Chaba ¹, Jason Soo ¹, Alison Clifford ¹, Jan Willem Cohen Tervaert ¹ and Elaine Yacyshyn ¹, ¹University of Alberta, Edmonton, Canada, ²University of Calgary, Calgary, Canada, ³Harvard, Boston, MA
Background/Purpose: Temporal arteritis or giant cell arteritis (GCA) is a large vessel vasculitis that involves extracranial arteries. The historical gold standard for diagnosis is a…
Abstract Number: 2686 • 2019 ACR/ARP Annual Meeting
Real Life Data over 4 Years from a Fast Track GCA Pathway in Coventry
Shirish Dubey¹, Jonathan Pinnell ², Carl Tiivas ¹, Kaushik Chaudhuri ¹ and Purnima Mehta ¹, ¹University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, ²University Hospital North Staffordshire NHS Trust, Stoke, United Kingdom
Background/Purpose: University Hospital Coventry and Warwickshire NHS Trust (UHCW) established its one stop Fast Track Pathway (FTP) for Giant Cell Arteritis (GCA) in 2013. It…
Abstract Number: 1836 • 2019 ACR/ARP Annual Meeting
Clinical Outcomes of Patients with Giant Cell Arteritis with Polymyalgia Symptoms Only vs Cranial Symptoms Only Treated with Tocilizumab or Placebo in a Randomized Clinical Trial
Robert Spiera¹, Sebastian Unizony ², Min Bao ³, Yves Luder ⁴, Páris Sidiropoulos ³, Jian Han ³, Jinglan Pei ³ and John Stone ², ¹Hospital for Special Surgery, New York, NY, ²Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, ³Genentech, South San Francisco, CA, ⁴F. Hoffmann-La Roche, Basel, Switzerland
Background/Purpose: GiACTA, a randomized, double-blind, placebo (PBO)–controlled study, demonstrated the efficacy and safety of tocilizumab (TCZ) in patients with giant cell arteritis (GCA).1 Growing evidence…
Abstract Number: 2662 • 2019 ACR/ARP Annual Meeting
Temporal Artery Biopsy Lengths in Alberta: Which Surgical Subspecialty Achieves Optimal Biopsy Lengths?
Raymond Chu¹, Caylea Foster ², Mohsin Ali ³, Todd Chaba ¹, Jason Soo ¹, Alison Clifford ¹, Jan Willem Cohen Tervaert ¹ and Elaine Yacyshyn ¹, ¹University of Alberta, Edmonton, Canada, ²University of Calgary, Calgary, Canada, ³Harvard, Boston, MA
Background/Purpose: Temporal arteritis or giant cell arteritis (GCA) is a large vessel vasculitis that involves extracranial arteries. Diagnosis requires a combination of clinical manifestations including…
Abstract Number: 2687 • 2019 ACR/ARP Annual Meeting
Clinicopathologic Associations in a Large International Cohort of Patients with Giant Cell Arteritis
Michael Putman¹, K Bates Gribbons ², Anthea Craven ³, Cristina Ponte ⁴, Joanna Robson ⁵, Ravi Suppiah ⁶, Richard Watts ⁷, Raashid Luqmani ³, Peter Merkel ⁸, Amy Archer ⁹ and Peter C. Grayson ¹⁰, ¹Northwestern University, Chicago, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ³University of Oxford, Oxford, United Kingdom, ⁴Department of Rheumatology, Hospital de Santa Maria, Lisbon, Portugal, ⁵Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, ⁶Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ⁷Norwich Medical School, University of East Anglia, Norwich, United Kingdom, ⁸University of Pennsylvania, Pennsylvania, ⁹Northwestern, Chicago, ¹⁰National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) of the National Institutes of Health, Bethesda, MD, Bethesda, MD
Background/Purpose: In addition to aiding in diagnosis, histopathologic findings from temporal artery biopsy (TAB) specimens in giant cell arteritis (GCA) may be valuable for their…
Abstract Number: 2764 • 2018 ACR/ARHP Annual Meeting
Incidence, Characteristics and Management of Giant Cell Arteritis in France: A Study Based on National Health Insurance Claims Data
Valérie Devauchelle-Pensec¹, Eric Hachulla², Marc Paccalin³, Sophie Gandon⁴, Isabelle Idier⁵, Maeva Nolin⁶, Manon Belhassen⁶ and Alfred Mahr⁷, ¹Department of Rheumatology and Unit of Immunology, University Medical School, Brest, France, ²Department of Internal Medicine, University Lille Nord-de-France, Lille, France, ³Department of Geriatric Medicine, University Hospital, Poitiers, France, ⁴Clinical Operation, Roche SAS, Boulogne-Billancourt, France, ⁵Medical department, Chugai Pharma France, Paris La Defense, France, ⁶PELyon, Pharmacoepidemiologie, Lyon, France, ⁷Hospital Saint-Louis, University Paris Diderot, Paris, France
Background/Purpose: Giant cell arteritis (GCA) is an immune-mediated, primary systemic vasculitis that affects large and medium-sized arteries. GCA may cause vision loss in up to…
Abstract Number: 823 • 2018 ACR/ARHP Annual Meeting
Survival of Biopsy Proven Giant Cell Arteritis in Northern Italy: Correlation with Clinical, Laboratory and Histopathological Findings
Luigi Boiardi¹, Pierluigi Macchioni², Francesco Muratore³, Mariagrazia Catanoso², Alberto Cavazza⁴, Pamela Mancuso⁵, Luca Cimino⁶, Giovanna Restuccia⁷ and Carlo Salvarani⁸, ¹Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, ²Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ³Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio Emilia, Italy, ⁴Pathology Unit, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, ⁵Interinstitutional Epidemiology Unit, Azienda USL di Reggio Emilia (Local Health Authority) and Azienda Ospedaliera IRCCS di Reggio Emilia,, Reggio Emilia, Italy, ⁶Ophthalmology Unit, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, ⁷Rheumatology Unitn, Arcispedale S Maria Nuova, IRCCS, 42100, Italy, ⁸Rheumatology Unit, Arcispedale Santa Maria Nuova - IRCCS; Università di Modena e Reggio Emilia, Reggio-Emilia, Italy
Background/Purpose: To correlate survival with clinical, laboratory and histopathological findings in a population based cohort of patients with biopsy-proven giant cell arteritis (GCA) living in…
Abstract Number: 2768 • 2018 ACR/ARHP Annual Meeting
Comorbidity Accrual and Mortality in an Inception Cohort of Patients with Giant Cell Arteritis and Polymyalgia Rheumatica: A Single-Center, Observational Long-Term Study
Elisheva Pokroy-Shapira¹, Ariela Dortort-Lazar^2,3 and Yair Molad^4,5, ¹Rheumatology Unit, Rabin Medical Center, Beilinson Hospital and Sackler Faculty of Medicine, Tel Aviv University, Petach Tikva, Israel, ²Rheumatology Unit, Beilinson hospital Rabin Medical Center, Petah Tikva, Israel, ³Sackler Faculty of Medicine Tel Aviv university, Tel Aviv, Israel, ⁴Rheumatology Unit, Rabin Medical Center, Beilinson Hospital, Petach Tikva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁵Rheumatology Unit, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel
Background/Purpose: Patients with giant-cell arteritis (GCA) and polymyalgia rheumatica (PMR) are treated with high cumulative glucocorticoid (GC) dose during their disease course. We sought to…
Abstract Number: 1883 • 2018 ACR/ARHP Annual Meeting
Infections Are Associated With Increased Risk of Giant Cell Arteritis – a Population-Based Case-Control Study From Southern Sweden
Pavlos Stamatis¹, Aleksandra Turkiewicz², Martin Englund², Goran Jönsson³, Jan-Åke Nilsson⁴, Carl Turesson⁵ and Aladdin Mohammad⁶, ¹Clinical Sciences, Rheumatology Lund, Lund University, Lund, Sweden, ²Clinical Sciences Lund, Clinical Epidemiology Unit, Lund University, Lund, Sweden, ³Clinical Sciences Lund, Department of Infection Medicine, Lund University, Lund, Sweden, ⁴Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, ⁵Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, ⁶Rheumatology, Department of Clinical Sciences, Lund, Lund University, Lund, Sweden
Background/Purpose: Previous studies have implicated infections as a risk factor for giant cell arteritis (GCA). The purpose of this study was to investigate the association…
Abstract Number: 2773 • 2018 ACR/ARHP Annual Meeting
Diagnostic and Therapeutic Management of a Suspected Case of GCA: An Opinion Survey
Henri Guillet¹, Raphaël Porcher², Alain Saraux³, Loïc Guillevin⁴, Luc Mouthon⁴ and Alexis Régent⁴, ¹Département d'aval des urgences, CHU Henri Mondor, Créteil, France, ²Université Paris Descartes Sorbonne Paris, Paris, France, ³Rheumatology, CHU Brest, Brest, France, ⁴Institut Cochin, INSERM U1016, CNRS UMR 8104, PARIS, France
Background/Purpose: Giant-cell arteritis (GCA) is the most common vasculitis. Specialists have formulated recommendations on how to manage a patient with a possible diagnosis of GCA.…

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