Abstracts tagged "gender"

Abstract Number: 2356 • ACR Convergence 2025
Clinical Efficacy in Male and Female Patients With Active Psoriatic Arthritis Treated With Deucravacitinib: A Pooled Analysis of Pivotal Phase 3 Studies
Lihi Eder¹, Philip J. Mease², Joseph F Merola³, Alexis Ogdie⁴, Atul Deodhar⁵, Laura Coates⁶, Stefan Varga⁷, Navya Kalapala⁷, Ying-Ming Jou⁸, Eleni Vritzali⁹ and Laure Gossec¹⁰, ¹University of Toronto, Toronto, ON, Canada, ²Department of Rheumatology, Providence-Swedish Medical Center and University of Washington, Seattle, WA, ³Department of Dermatology and Department of Medicine, UT Southwestern Medical Center, Dallas, TX, ⁴Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Wilmington, DE, ⁵Division of Arthritis and Rheumatic Diseases, Oregon Health & Science University, Portland, OR, ⁶Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, England, United Kingdom, ⁷Bristol Myers Squibb, Princeton, NJ, ⁸Bristol Myers Squibb, Princeton, ⁹Bristol Myers Squibb, Boudry, Switzerland, ¹⁰Sorbonne Universite and Pitie-Salpetriere Hospital, Paris, France
Background/Purpose: PsA affects male and female patients equally; however, variations in clinical manifestations and treatment responses between sexes have been reported. Deucravacitinib is an oral,…
Abstract Number: 0589 • ACR Convergence 2025
Comparing Efficacy of Upadacitinib in Male and Female Patients with axSpA: Results from the SELECT-AXIS 1 and 2 Trials
Sofia Ramiro¹, Anna Molto², Elena Nikiphorou³, Marcelo Pinheiro⁴, Jamie Urbanik⁵, Tianming Gao⁶, Shirley Chen⁷, Jayne Stigler⁸, Jessica A. Walsh⁹ and Lihi Eder¹⁰, ¹Leiden University Medical Center, Bunde, Netherlands, ²Assistance Publique Hôpitauxde Paris, Paris, France, ³King's College London, London, United Kingdom, ⁴UNIFESP/ EPM, São Paulo, São Paulo, Brazil, ⁵AbbVie, Grayslake, IL, ⁶AbbVie, North Chicago, IL, ⁷AbbVie, Somerset, NJ, ⁸AbbVie, Round Lake, IL, ⁹Division of Rheumatology, Salt Lake City Veterans Affairs Health and University of Utah Health, Salt Lake City, UT, ¹⁰University of Toronto, Toronto, ON, Canada
Background/Purpose: Evidence suggests that the treatment effectiveness of TNFis and IL-17is is higher in male (M) vs female (F) patients (pts) with axSpA.1,2 Data comparing…
Abstract Number: 2322 • ACR Convergence 2025
Gender-related Differences in Peripheral and Axial Spondyloarthritis
Mehmet Tuncay Duruöz¹, Halise Hande Gezer¹, İlknur Aktaş², Servet Akar³, Nilay Şahin⁴, Özgür Akgül⁵, Sami Hizmetli⁶, Meltem Alkan Melikoğlu⁷, Umut Kalyoncu⁸, Erhan Çapkın⁹, fatma Gülçin Ural¹⁰, Figen Yılmaz¹¹, Sebnem ATAMAN¹² and İlhan Sezer¹³, ¹Marmara University Medical School PMR Department, Rheumatology Division, Istanbul, Turkey, ²Istanbul Fatih Sultan Mehmet Training and Research Hospital, PMR, Turkey, Istanbul, Turkey, ³Department of Medicine, Izmir Katip Çelebi University School of Medicine, Izmir, Turkey, ⁴Balikesir University School of Medicine, PMR, Turkey, Balıkesir, Turkey, ⁵Manisa Celal Bayar University School of Medicine, Rheumatology, Turkey, Manisa, Turkey, ⁶Sivas Cumhuriyet University School of Medine, Rheumatology, Turkey, Sivas, Turkey, ⁷Erzurum Atatürk University School of Medicine, Rheumatology, Turkey, Erzurum, Turkey, ⁸Division of Rheumatology, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey, Ankara, Turkey, ⁹Karadeniz Teknik University School of Medicine, PMR, Turkey, Trabzon, Turkey, ¹⁰Ankara Yildirim Beyazit University School of Medicine, PMR, Turkey, Ankara, Turkey, ¹¹Istanbul Sisli Etfal Training and Research Hospital, PMR, Turkey, Istanbul, Turkey, ¹²Ankara University School of Medicine, Rheumatology, Turkey, Ankara, Turkey, ¹³Akdeniz University School of Medicine, Rheumatology, Turkey, Antalya, Turkey
Background/Purpose: This study sought to compare clinical characteristics between female and male patients with spondyloarthritis (SpA) in a Turkish population.Methods: This study included 489 peripheral…
Abstract Number: 0557 • ACR Convergence 2025
Efficacy of Upadacitinib in Male and Female Patients with PsA: Results from the SELECT-PsA 1 and 2 Trials
Lihi Eder¹, Axel Hueber², Lucia Novelli³, Tianming Gao³, Jayne Stigler⁴, Zhiyuan Du³, Rodrigo García Salinas⁵, Grace Wright⁶ and Sofia Ramiro⁷, ¹University of Toronto, Toronto, ON, Canada, ²Klinikum Nuernberg, Nuernberg, Germany, ³AbbVie, North Chicago, IL, ⁴AbbVie, Round Lake, IL, ⁵Hospital Italiano La Plata, La Plata, Argentina, ⁶Grace C Wright MD PC, New York, NY, ⁷Leiden University Medical Center, Bunde, Netherlands
Background/Purpose: Biologic sex can impact both clinical phenotype and therapeutic response in PsA.1–3 Previous studies have suggested that male patients (pts) may achieve better treatment…
Abstract Number: 2264 • ACR Convergence 2025
Male Sex and Obesity Are Risk Factors for Sarcopenia in RA: Korea National Health and Nutrition Survey 2008–2011
Yoon-Jeong Oh¹, Jin-Wuk Hur² and Chang-Nam Son³, ¹Uijeongbu Eulji Medical Center, Eulji University School of Medicine, Uijeongbu, Republic of Korea, ²Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Republic of Korea, ³UIJEONGBU EULJI MEDICAL CENTER, EULJI UNIVERSITY, UIJEONGBU, Republic of Korea
Background/Purpose: Sarcopenia is a medical condition characterized by the progressive loss of skeletal muscle mass, strength, and function. It is primarily associated with aging, but…
Abstract Number: 0873 • ACR Convergence 2025
Sex Differences in Proteomic Profiles and the Impact of Deucravacitinib Treatment in Patients with Active Psoriatic Arthritis: A Pooled Phase 3 Analysis
Lihi Eder¹, Shangzhong Li², Philip J. Mease³, Christopher Ritchlin⁴, Walter P Maksymowych⁵, Hendrik Schulze-Koops⁶, Josef Smolen⁷, Oliver FitzGerald⁸, Vinod Chandran⁹, Chun Wu¹⁰ and Jinqi Liu², ¹University of Toronto, Toronto, ON, Canada, ²Bristol Myers Squibb, Princeton, NJ, ³Department of Rheumatology, Providence-Swedish Medical Center and University of Washington, Seattle, WA, ⁴University of Rochester Medical Center, Canandaigua, NY, ⁵Department of Medicine, University of Alberta, Edmonton, AB, Canada, ⁶LMU Hospital, Division for Rheumatology and Clinical Immunology, Munich, Bayern, Germany, ⁷Division of Rheumatology, Department of Medicine ³, Medical University of Vienna, Vienna, Austria, Vienna, Austria, ⁸UCD, Dublin ⁶, Dublin, Ireland, ⁹Division of Rheumatology, Departments of Medicine and Laboratory Medicine and Pathobiology, University of Toronto, and Gladman Krembil Psoriatic Arthritis Research Program, Krembil Research Institute, University Health Network, Toronto, Canada, ¹⁰Bristol Myers Squibb, Princeton
Background/Purpose: PsA affects male and female patients equally; however, variations in manifestations and treatment response exist between sexes. Deucravacitinib is an oral, selective, allosteric tyrosine…
Abstract Number: 2196 • ACR Convergence 2025
Recognition and Treatment of Idiopathic Granulomatous Mastitis: A Case Series
Jenny Solomon¹, Julie Piccione¹, Julie Nusbaum², Steven Carsons³ and Gregg Blumberg¹, ¹NYU Langone Long Island, Mineola, ²NYU Langone Health, New York, NY, ³NYU Long Island School of Medicine, Mineola, NY
Background/Purpose: Idiopathic Granulomatous Mastitis (IGM) is a rare benign inflammatory condition of the breast usually affecting women of childbearing age with a history of breastfeeding.…
Abstract Number: 0841 • ACR Convergence 2025
Comparing the Impact of GLP-1 Agonists and SGLT-2 Inhibitors on Outcomes in Lupus Nephritis: A Retrospective Cohort Study
Kinga Grzybowski¹ and Irene Tan², ¹Jefferson Einstein Montgomery Hospital, Maspeth, NY, ²Einstein Healthcare Network Philadelphia - Jefferson Health, Bala Cynwyd, PA
Background/Purpose: Lupus Nephritis (LN) is one of the most serious complications of SLE (Systemic Lupus Erythematosus) characterized by an attack of the kidneys by the…
Abstract Number: 1935 • ACR Convergence 2025
Sex-associated disparities in industry payments to US authors in high-impact rheumatology journals correlate with author impact
William Stohl¹, Krishan Parikh¹, Anuj Parikh² and Sheldon Stohl³, ¹University of Southern California, Los Angeles, CA, ²Cerritos High School, Cerritos, CA, ³Hadassah Medical Center, Jerusalem, Israel
Background/Purpose: To assess sex-associated disparities in industry payments to US physician-authors in high-impact rheumatology journals and their correlation with author impact.Methods: US authors of publications…
Abstract Number: 0744 • ACR Convergence 2025
Age and Sex Influence on Clinical Manifestations of Giant Cell Arteritis: Results from the ARTESER Registry
Delia Fernandez-Lozano¹, Marta Domínguez-Álvaro², Javier Narváez³, Noemí Garrido⁴, Eugenio de Miguel⁵, Paula Estrada-Alarcón⁶, Iñigo Hernández-Rodríguez⁷, Maite Silva-Diaz⁸, Joaquín M Belzunegui⁹, Clara Moriano¹⁰, Julio Sánchez Martín¹¹, Itziar Calvo-Zorrilla¹², Vicente Aldasoro Cáceres¹³, lydia Abasolo Alcazar¹⁴, Javier Loricera¹⁵, rafeal Benito-Melero¹⁶, Maria Garcia-Villanueva¹⁷, Fernando Sánchez-Alonso², Santos Castañeda¹⁸, José L. Hernández¹⁹ and Ricardo Blanco²⁰, ¹Hospital Universitario y Politecnico La Fe, Valencia, Spain, ²Sociedad Española de Reumatología, Madrid, Spain, ³Hospital Universitario de Bellvitge, Barcelona, Spain, ⁴Hospital Universitario Virgen del Rocío, Sevilla, Andalucia, Spain, ⁵Hospital Universitario La Paz, Madrid, Spain, ⁶Hospital de San Juan Despí Moisès Broggi, Barcelona, Spain, ⁷Complejo Hospitalario Universitario de Vigo, Vigo, Spain, ⁸Complexo Hospitalario Universitario A Coruña, A Coruña, Galicia, Spain, ⁹Hospital Universitario Donostia, San Sebastian, Spain, ¹⁰Hospital León, LEON, Castilla y Leon, Spain, ¹¹Hospital Universitario ¹² de Octubre, Madrid, Spain, ¹²Galdakao-Usansolo University Hospital, Bilbao, Spain, ¹³Hospital Universitario de Navarra, Pamplona, Spain, ¹⁴IdISSC. HCSC, Madrid, Madrid, Spain, ¹⁵Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, ¹⁶MD, barcelona, Spain, ¹⁷Hospital Ramón y Cajal, Madrid, Spain, ¹⁸Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, ¹⁹Instituto de Investigación Marqués de Valdecilla (IDIVAL), Universidad de Cantabria, Santander, Spain, ²⁰Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain
Background/Purpose: Giant cell arteritis (GCA) is a large vessel vasculitis that predominantly affects older adults, with a higher prevalence in women. Previous studies exploring sex-related…
Abstract Number: 1877 • ACR Convergence 2025
Demographics and trends of Inflammatory Arthritis-Related Mortality in the United States, 1999–2019
Aishwarya Sudheer¹, Ishan Jani², Sarath Lal Mannumbeth Renjithlal² and Qi Wang³, ¹Saint Vincent Hospital, Worcester, MA, ²Rochester General Hospital, Rochester, NY, ³Metrohealth System/Case Western Reserve University, Cleveland, OH
Background/Purpose: The study aims to evaluate the racial, sex-related and urbanization-related trends of deaths in patients with inflammatory polyarthropathies in the United States between 1999…
Abstract Number: 0462 • ACR Convergence 2025
Does Biological Sex Affect Mortality in Frail Patients with Rheumatoid Arthritis?
Sayuli Bhide¹, Hannah Brubeck², Punyasha Roul³, Aaron Baraff², Bryant England⁴, Nadine El-Ayache¹, Grant Cannon⁵, Namrata Singh⁶, Gary Kunkel⁷, Ted Mikuls⁴, Dolores Shoback⁸, Kaleb Michaud⁴, Patti Katz⁹, Jose Garcia¹⁰, Ariela Orkaby¹¹, Joshua Baker¹² and Katherine Wysham¹³, ¹University of Washington, Seattle, WA, ²VA Puget Sound Health Care System, Seattle, WA, ³UNMC, Omaha, NE, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵University of Utah and Salt Lake City VA, Salt Lake City, UT, ⁶University of Washington, Bellevue, WA, ⁷University of Utah and George E Wahlen VAMC, Salt Lake City, UT, ⁸San Francisco VA Medical Center & University of California San Francisco, San Francisco, CA, ⁹UCSF, San Rafael, CA, ¹⁰VA Puget Sound Health Care System, VA GRECC, and University of Washington, Seattle, WA, ¹¹Veterans Affairs Boston Healthcare System & Brigham and Women’s Hospital, Boston, MA, ¹²University of Pennsylvania, Philadelphia, PA, ¹³VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA
Background/Purpose: Frailty predicts mortality in RA. In the general population, males have a higher risk of death than females despite lower levels of frailty.1 We…
Abstract Number: 1837 • ACR Convergence 2025
Enhanced Mitochondrial Activity in B cells from Females Is Required to Drive Increased T-bet Induction by TLR7 in Lupus
John D. Mountz¹, Kathryn Sullivan², Shanrun Liu², Cynthia Liu², Min Gao², Walter Winn Chatham³, Tanecia Mitchell² and Hui-Chen Hsu², ¹University Alabama Birmingham, Birmingham, AL, ²University of Alabama at Birmingham, Birmingham, AL, ³University of Nevada, Las Vegas, Las Vegas, NV
Background/Purpose: Systemic lupus erythematosus (SLE) is a predominantly female autoimmune disease, with a 9:1 female-to-male ratio. Our previous studies indicated that increased T-bet+ age-related B…
Abstract Number: 0356 • ACR Convergence 2025
An Analysis of Osteoporosis Screening in Males 50 and Older with Rheumatic Disease across Stony Brook Medicine Network
Stephen Poos¹, Hoang Nguyen², Samuel Greenberg³, Marcus Lee², Heidi Roppelt¹ and Asha Patnaik², ¹Stony Brook Southampton Hospital, Southampton, NY, ²Stony Brook University Hospital, Stony Brook, NY, ³Renaissance School of Medicine at Stony Brook University, Stony Brook, NY
Background/Purpose: Osteoporosis is under screened in men. The United States Preventive Services Task Force (USPSTF) does not publish guidelines for osteoporosis screening in men. Other…
Abstract Number: 1714 • ACR Convergence 2025
The perimenopause period is associated with increased levels of disease activity in psoriatic arthritis
Lihi Eder¹, Xianwei Li², Sahil Koppikar³, Iliana Lega⁴, Dafna D. Gladman⁵, Vinod Chandran¹ and Richard Cook⁶, ¹University of Toronto, Toronto, ON, Canada, ²Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, Canada, ³Women's College Hospital & University of Toronto, Markham, ON, Canada, ⁴University of Toronto and Women’s College Hospital, Toronto, Canada, ⁵Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada, ⁶University of Waterloo, Waterloo, Canada
Background/Purpose: Perimenopause is associated with a wide spectrum of symptoms, including mood changes, sleep disturbances, and joint pains. Limited information exists on the effect of…

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