Abstracts tagged "gender"

Abstract Number: 0578 • ACR Convergence 2024
Gender Differences in Disease Parameters, Adherence to Treat to Target Strategy and Outcomes in Axial Spondyloarthritis (axSpA) in Pakistani Cohort
Muhammad Saeed¹, HIna Ahmed² and Aziza Ahmed³, and Arthritis Carte Foundation Faculty, ¹Central Park Medical College, Arthritis Care Foundation, Lahore, Pakistan, ²Central Park Medical College, Lahore, Pakistan, ³Rashid Latif Medical College, Lahore, Pakistan
Background/Purpose: In patients with Axial Spondyloarthritis (axSpA) there has been wide variability in terms of gender regarding disease characteristics as well as outcomes across different…
Abstract Number: 1708 • ACR Convergence 2024
Unveiling the Uterine-Joint Axis: Dysbiosis and Subclinical Uterine Inflammation in Female Axial Spondyloarthritis Pathogenesis
Daniele Mauro¹, Matteo Vecellio², Anne-Sophie Bergot³, Eva Schmid⁴, Giulio Forte⁵, Alessia Stingo⁶, Alessia Salzillo⁵, Aldo Pastore⁷, Paolo Aretini⁷, Francesca Di Lorenzo⁷, Antonio ciancio⁵, Ilenia Pantano⁵, Gabriele Saccone⁸, Fulvio Zullo⁹, carlo Maurizio Montecucco¹⁰, Aroldo Rizzo¹¹, Georg Schett¹², Ranjeny Thomas¹³, Mario Zaiss¹⁴ and Francesco Ciccia¹⁵, ¹University of Campania, Italy, Naples, Naples, Italy, ²Fondazione Pisana per la Scienza ONLUS, Pisa, Italy, ³Frazer Institute, University of Queensland, Brisbane, Australia, ⁴Friedrich-Alexander-University Erlangen-Nürnberg (FAU), Rheumatology and Immunology, Erlangen, Erlangen, Germany, ⁵University of Campania L. Vanvitelli, Naples, Italy, ⁶University of Campania L. Vanvitelli, Nasples, Italy, ⁷Fondazione Pisana per la Scienza ONLUS, Giuliano Terme, Italy, ⁸University Federico II of Naples, Naples, Italy, ⁹University of Catanzaro, Catanzaro, Italy, ¹⁰Unit of Rheumatology, Fondazione IRCCS Policlinico San Matteo and University of Pavia, Pavia, Italy, ¹¹Azienda Ospedaliera Ospedali riuniti Villa Sofia Cervello,, Palermo, Italy, ¹²Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany, ¹³University of Queensland, Brisbane, Australia, ¹⁴Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg (FAU) and Universittsklinikum Erlangen, Erlangen, Germany; 2 Deutsches Zentrum für Immuntherapie (DZI), Erlangen, Germany, ¹⁵Università degli studi della Campania Luigi Vanvitelli, Naples, Italy
Background/Purpose: Numerous studies exploring gender differences in axial spondyloarthritis (AxSpA) have noted that women exhibit distinct disease manifestations. Yet, a definitive pathophysiological distinction of these diverse…
Abstract Number: 0588 • ACR Convergence 2024
Sex-Related Differences in Baseline Patient and Disease Characteristics: Post Hoc Analyses of Three Phase 3, Randomized, Double-blind, Placebo-Controlled Studies in Patients with Active Psoriatic Arthritis
Laura Coates¹, Carlo Selmi², Philip Mease³, Alexis Ogdie⁴, Francois Nantel⁵, Frederic Lavie⁶, Mohamed Sharaf⁷, Oyediran Adelakun⁸, Emmanouil Rampakakis⁹, Laura Pina Vegas¹⁰ and Lihi Eder¹¹, ¹University of Oxford, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Oxford, United Kingdom, ²Department of Biomedical Sciences, Humanitas University, Rozzano, Italy, ³Swedish Medical Center/Providence St. Joseph Health; University of Washington School of Medicine, Seattle, WA, ⁴Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ⁵Nantel MedSci Consult, Montreal, QC, Canada, ⁶Janssen Cilag Global Medical Affairs, Immunology Global Medical Affairs, Issy les Moulineaux, France, ⁷Johnson & Johnson, Middle East FZ LLC, Dubai, UAE, Dubai, United Arab Emirates, ⁸Janssen Research & Development, LLC, Titusville, NJ, ⁹McGill University, Department of Pediatrics / Scientific Affairs, JSS Medical Research Inc., Montreal, QC, Canada, ¹⁰Leiden University Medical Center, Leiden, Netherlands, ¹¹University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada
Background/Purpose: Although PsA occurs in males and females at similar rates, clinical manifestations and outcomes differ between sexes. Findings from real-world evidence (RWE) studies have…
Abstract Number: 1709 • ACR Convergence 2024
Sex Differences in Serum Proteomic Profiles of Males and Females with Psoriatic Arthritis
Steven Dang¹, Xianwei Li², Liqun Diao², Joan Wither³, Igor Jurisica⁴, Vinod Chandran⁵ and Lihi Eder⁶, ¹Women's College Hospital, Institute of Medical Science, University of Toronto, Toronto, ON, Canada, ²Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ³University Health Network, Toronto, ON, Canada, ⁴Departments of Medical Biophysics and Computer Science and Faculty of Dentistry, University of Toronto and Institute of Neuroimmunology, Slovak Academy of Sciences, Bratislava, Slovakia, Toronto, ON, Canada, ⁵University of Toronto, Toronto, ON, Canada, ⁶University of Toronto, Women’s College Hospital and Department of Medicine, Toronto, ON, Canada
Background/Purpose: Psoriatic arthritis (PsA) affects males and females equally, but differences exist in the clinical presentation and treatment response. The biological mechanisms driving these differences…
Abstract Number: 0599 • ACR Convergence 2024
Sex- related Differences in Efficacy of Biologics in Axial Spondyloarthritis: A Systematic Review and Meta-analysis
Haseeb Chaudhary¹, Omer Pamuk², Sarah Abi Doumeth³, Ansaam Daoud⁴, Muhammad Shamim⁵ and Marina Magrey⁶, ¹Case Western Reserve University, Westlake, OH, ²University Hospitals Cleveland Medical Center/ Case Western Reserve University, Cleveland, OH, ³Case Western Reserve University/University Hospitals Cleveland Medical Center, Cleveland Heights, OH, ⁴Case Western Reserve University/University Hospitals, Akron, OH, ⁵University Hospitals/ Case Western Reserve University, Cuyahoga Falls, OH, ⁶Case Western Reserve University School of Medicine/University Hospitals, Richfield, OH
Background/Purpose: There is limited information about sex-related differences in efficacy of biologics in axial spondyloarthritis (axSpA). We hypothesized that females with axSpA are less likely…
Abstract Number: 1924 • ACR Convergence 2024
Racial and Gender Disparities in Psoriatic Arthritis Clinical Trials
Dania Kaur¹, Fizza Zulfiqar², Akshee Batra³ and Abhinav Vyas⁴, ¹North Alabama Medical Center, Muscle Shoals, AL, ²Trinity Health Oakland/Wayne State University, Pontiac, MI, ³University of Miami, Miami, FL, ⁴Vanderbilt University Medical Center, Nahville, TN
Background/Purpose: To develop effective novel treatment strategies for psoriatic arthritis that cater to patients from diverse backgrounds, it is crucial that all racial groups, without…
Abstract Number: 0782 • ACR Convergence 2024
30-Color Full Spectrum Flow Cytometry Identifies Sex Differences in the Circulating Immune Landscape of Systemic Sclerosis
Sylvia Posso¹, Jane Buckner², Montserrat Anguera³ and Nikhil Jiwrajka⁴, ¹Benaroya Research Institute at Virginia Mason, Seattle, WA, ²Benaroya Research Institute, Seattle, WA, ³University of Pennsylvania, Philadelphia, PA, ⁴Hospital of the University of Pennsylvania, Philadelphia, PA
Background/Purpose: Systemic sclerosis (SSc) is a heavily female-biased systemic autoimmune disease associated with significant morbidity and mortality due to fibrosis of the skin and vital…
Abstract Number: 2029 • ACR Convergence 2024
Iron Deficiency in Familial Mediterranean Fever: A Study on 211 Adult Patients from the JIR Cohort
Ilenia Di Cola¹, Lea Savey², Marion Delplanque³, Rim bourguiba³, Alessandra Bartoli⁴, Zohra Aknouche³, Fatima Bensalek³, Isabelle Kone Paut⁵, Linda Rossi Semerano⁵, Isabelle Melki⁶, Brigitte Bader-Meunier⁷, Bénédicte Neven⁶, PIERRE QUARTIER⁸, Guilaine Boursier⁹, Irina Giurgea¹⁰, Laurence Cuisset¹¹, Gilles Grateau³, Veronique Hentgen¹² and Sophie Georgin-lavialle¹³, ¹University of L'Aquila, L'Aquila, Italy, ²Internal Medicine Department, Tenon Hospital, AP-HP, Paris, France, france, France, ³Internal Medicine Department, Tenon Hospital, AP-HP, Paris, France, Paris, France, ⁴Internal Medicine Department, Tenon Hospital, AP-HP, Paris, France, italy, Italy, ⁵Kremlin Bicêtre hospital, Le Kremlin Bicêtre, France, ⁶Necker Hospital, Paris, France, ⁷Necker Hospital, Assistance Publique Hopitaux de Paris, Paris, France, ⁸Université Paris-Cite, IMAGINE Institute, Necker Children’s Hospital, Paris Cedex 15, France, ⁹University of Montpellier, Montpellier, ¹⁰Trousseau hospital, Paris, France, ¹¹Cochin hospital, Paris, France, ¹²Laboratoire de Génétique des Maladies Rares et Autoinflammatoires, Département de Génétique Médicale, Maladies Rares et Médecine Personnalisée, CEREMAIA, CHU de Montpellier, Univ Montpellier, Montpellier, France, Le Chesnay, France, ¹³Sorbonne Université, Department of internal medicine, Tenon Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France
Background/Purpose: Familial Mediterranean fever (FMF) is the most common monogenic autoinflammatory disease worldwide. Fatigue is known to trigger FMF attacks. So far, no association has…
Abstract Number: 0847 • ACR Convergence 2024
Sex and Race-Specific Distributions in Medial Fixed Joint Space Width in Healthy Knees from Three Longitudinal Cohorts
Kent Kwoh¹, Rongrong Tang², Erin Ashbeck³, Edward Bedrick⁴, Yvonne Golightly⁵, Amanda Nelson⁶, Tuhina Neogi⁷, Yong Ge⁸, Zong-Ming Li², Jean Liew⁷, Xiaoxiao Sun⁹, Justin Crawmer¹⁰ and Jeffery Duryea¹¹, ¹University of Arizona, Tucson, AZ, ²University of Arizona Arthritis Center, University of Arizona College of Medicine - Tucson, Tucson, AZ, ³University of Arizona Mel and Enid Zuckerman College of Public Health, Tucson, AZ, ⁴Department of Epidemiology andBiostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, ⁵University of Nebraska Medical Center, Omaha, NE, ⁶University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁷Boston University Chobanian & Avedisian School of Medicine, Boston, MA, ⁸Department of Information Sciences, Eller College of Manangement, University of Arizona, Tucson, AZ, ⁹Department of Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, ¹⁰BWH, Boston, MA, ¹¹Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Quantitative radiographic joint space width (JSW) is often used as ameasure of structural outcomes in randomized controlled trials of knee OA (KOA). How JSW…
Abstract Number: 2146 • ACR Convergence 2024
Validation of the Simple Calculated Osteoporosis Risk Estimation and Osteoporosis Self-assessment Tool Among People Aging with HIV in Peru
Joselito Malca-Hernandez¹, Daniel Granda², Ahmed Abdeen³, Yvett Pinedo⁴, Flor Gonzales⁵, Miguel Tapia⁶, Patricia Garcia⁷ and Evelyn Hsieh⁸, ¹Yale School of Public Health, Department of Epidemiology of Microbial Diseases / School of Public Health- Universidad Peruana Cayetano Heredia, Epidemiology, STD, and HIV Unit, New Haven, CT, ²Universidad Peruana Cayetano Heredia, Facultad de Medicina Alberto Hurtado, Lima, Lima, Peru, ³Yale School of Medicine, Section of Rheumatology, Allergy and Immunology / Penn State College of Medicine, State College, New Haven, CT, ⁴Hospital Nacional Arzobispo Loayza, Department of Infectious Diseases, Lima, Peru, ⁵Ministry of Health of Peru, Department of Infectious Diseases, Lima, Peru, ⁶Ministry of Health, Department of Infectious Diseases, Lima, Peru, ⁷School of Public Health- Universidad Peruana Cayetano Heredia, Epidemiology, STD, and HIV Unit, Lima, Peru, ⁸Yale School of Medicine / VA Connecticut Healthcare System, West Haven, Connecticut, New Haven, CT
Background/Purpose: The life expectancy of people living with HIV (PLWH) has improved notably since the advent of antiretroviral therapy (ART). However, studies have shown that…
Abstract Number: 0976 • ACR Convergence 2024
Assessment of Current Trends in Demographic and Clinical Characteristics of Male Patients with Rheumatoid Arthritis in North India
BHARAT KUMAR SINGH¹ and Seema Singh², ¹CK Birla Hospitals, Jaipur, JAIPUR, Rajasthan, India, ²RAJASTHAN UNIVERSITY OF HEALTH SCIENCES, JAIPUR, Rajasthan, India
Background/Purpose: Gender differences in rheumatoid arthritis (RA) are well-established, with women more prone to developing RA than men. However, understanding the impact of gender on…
Abstract Number: 2255 • ACR Convergence 2024
Differences in Pharmacological Prescription to Patients with Recent-onset Arthritis: Analysis from the Gender Perspective
Maryia Nikitsina, María Ahijón Lana and Isidoro González-Álvaro, University Hospital La Princesa, Madrid, Madrid, Spain
Background/Purpose: Nowadays the honing in on sex-specific treatment options is the most productive way to move forward with the larger effort of implementing precision medicine.…
Abstract Number: 1025 • ACR Convergence 2024
Gender Disparities in Disease Impact and Treatment Access for Spondyloarthropathies in Latin America: Insights from a Web Survey
Sebastián Ibáñez¹, María Dominga García¹ and Natalia González², ¹Clínica Alemana de Santiago, Santiago, Region Metropolitana, Chile, ²Fundación Espondilitis Chile, Santiago, Region Metropolitana, Chile
Background/Purpose: Previous studies have shown that female patients with spondyloarthritis (SpA) tend to experience a greater impact on their functionality, especially among women in Latin…
Abstract Number: 2316 • ACR Convergence 2024
Gene Expression Profile Is Different Between Men and Women in Psoriatic Disease
Pauline KRUG¹, angela De Sousa Leite², Frédéric Lecouvet¹, Maria Simona stoenoiu¹ and Adrien Nzeusseu Toukap³, ¹Cliniques universitaires St-Luc, Brussel, Belgium, ²Cliniques universitaires St-Luc, Brussels, Belgium, ³Cliniques universitaires Saint-Luc,, St.-Lambrechts-Woluwe, Belgium
Background/Purpose: Psoriatic arthritis (PsA) is a highly heterogenous chronic inflammatory condition. Recent publications highlight differences between men and women in disease manifestation and response to…
Abstract Number: 1033 • ACR Convergence 2024
Osteoporosis and Cardiovascular Disease: Mortality Trends Among Adults in the United States from 1999 to 2020
Muhammad Naveed¹, Farman Ali², Ahila Ali¹, Bazil Azeem³, Faizan Ahmed⁴, Rabia Iqbal¹, Muhammad Omer Rehan¹, Nouman Shafique⁵, Syed Ishaq⁶, Aman Ullah⁷ and Sherif Eltawansy⁸, ¹Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan, ²Corewell Health, Dearborn Hospital, Dearborn, MI, Dearborn, MI, ³Shaheed Mohtarma Benazir Bhutto Medical College Liyari, Karachi, Pakistan, ⁴Ameer-ud-Din Medical College, Lahore, Pakistan, ⁵AdventHealth Orlando, Orlando, FL, ⁶Sinai Hospital of Baltimore, Baltimore, MD, ⁷SSM Health St Louis University Hospital, St. Louis, MO, ⁸Jersey Shore University Medical Centre, Neptune, NJ
Background/Purpose: Osteoporosis and cardiovascular disease (CVD) represent significant public health concerns. This study investigates the trends and demographic disparities in mortality due to osteoporosis and…

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