Abstracts tagged "gender"

Abstract Number: 1101 • ACR Convergence 2022
Sex and Racial Differences in Systemic Lupus Erythematosus Among U.S. Adults in the All of Us Research Program
Rachel Elam¹, Deepak Ayyala¹, Adria Madera-Acosta¹, Stephen Bell¹, Anam Qureshi¹, Christopher Rice², Laura Carbone¹, Steven Coughlin¹ and Hong Shi³, ¹Augusta University, Augusta, GA, ²Moses H. Cone Memorial Hospital, Augusta, GA, ³Department of Internal Medicine/Division of Rheumatology, Vascular Biology Center, Augusta, GA
Background/Purpose: Most persons with systemic lupus erythematosus (SLE) are women, and men with SLE are an understudied demographic. The purpose of this study was to…
Abstract Number: 1153 • ACR Convergence 2022
Differentially Expressed Genes in Males and Females with Ankylosing Spondylitis (AS): Transcriptomics of IL-17-producing Cells in Patients with AS
Chan Mi Lee¹, Ricky Chan², Maricela Haghiac³ and Marina Magrey⁴, ¹University Hospitals, Cleveland, OH, ²Case Western Reserve University, Cleveland, OH, ³Metrohealth Medical Center, Cleveland, OH, ⁴Case Western Reserve University, University Hospitals, Richfield, OH
Background/Purpose: Unlike most autoimmune diseases, ankylosing spondylitis (AS) is more frequently diagnosed in men (3:1) and with a higher radiographic progression compared to women. Th17…
Abstract Number: 1158 • ACR Convergence 2022
Differential Plasma Levels of S100 Proteins in Male versus Female Patients with Ankylosing Spondylitis
Chan Mi Lee¹, Maricela Haghiac² and Marina Magrey³, ¹University Hospitals, Cleveland, OH, ²Metrohealth Medical Center, Cleveland, OH, ³Case Western Reserve University, University Hospitals, Richfield, OH
Background/Purpose: S100 proteins are a family of 25 calcium-binding cytosolic proteins which are involved in stress and inflammatory responses. S100A4 acts as a negative regulator…
Abstract Number: 1178 • ACR Convergence 2022
Key Features of Human Fibrosing Interstitial Lung Disease Are Captured in a Preclinical Mouse Model upon Repetitive, but Not Single Intratracheal Bleomycin Dosing
David Lauer¹, Janine Schniering², Matthias Brunner¹, Chantal Meier³, Kerstin Klein¹, Oliver Distler⁴ and Britta Maurer¹, ¹Department of Rheumatology and Immunology, University Hospital Bern, University of Bern, Bern, Switzerland, ²Helmholtz Zentrum München, Institute of Lung Health and Immunity (LHI), Comprehensive Pneumonology Center, Munich, Germany, ³Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Schlieren, Switzerland, ⁴Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland
Background/Purpose: Repetitive alveolar epithelial injury together with dysregulated tissue repair is crucial for the transition of acute self-limiting to chronic-persisting inflammation and fibrosis in fibrosing…
Abstract Number: 1219 • ACR Convergence 2022
Gender-Related Clinical Profile of Fibromyalgia Patients
Mark Berman¹, Liane banon², Omer Shlezinger³, Laurence Mangel⁴, Jacob Ablin¹ and Valerie Aloush⁵, ¹Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ²Department of Gastroenterology and Hepatolgy, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, ³Internal Medicine F, Tel Aviv, Israel, ⁴Sackler faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, ⁵Tel Aviv Medical Center, Tel Aviv, Israel
Background/Purpose: Fibromyalgia is a chronic pain disorder characterized by widespread pain, fatigue, sleep disturbances, cognitive dysfunction and frequent psychiatric comorbidities. Estimated prevalence of fibromyalgia is…
Abstract Number: 0085 • ACR Convergence 2022
Closing the Gender Gap in Global Rheumatology Leadership- Are We There Yet?
Tayyeba Khursheed¹, Pavel Ovseiko², Ghita Harifi³, Humeira Badsha⁴, Harish G Shekar⁵ and Latika Gupta⁶, ¹Pakistan Institute of Medical Sciences, Islamabad, Pakistan, ²John Radcliffe Hospital, Oxford, Oxford, United Kingdom, ³Department of Rheumatology, Mediclinic Parkview Hospital, Dubai, United Arab Emirates, ⁴Dr. Humeira Badsha Medical Center, Dubai, United Arab Emirates, ⁵Rajarajeswari medical College and hospital, Bangalore, India, ⁶Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom
Background/Purpose: The gender equity in academic rheumatology initiative has sparked discussions on the effect of inequity in academia on assignment to leadership roles. To explore…
Abstract Number: 1225 • ACR Convergence 2022
Sphygmomanometry for Fibromyalgia Detection in a Rheumatology Outpatient Clinic. a Cross-sectional Study
Viridiana Del Río Guerrero¹, Laura Aline Martínez Martínez¹, Karina Arias Callejas¹, Natalia Carbonell-Bobadilla², Alejandra Mejía Segura¹, Gibrán Azamar Morales¹, Alejandra Espinosa Orantes¹, Mauricio Mora Ramírez¹, Fernanda Mejía Ávila¹, Raúl Molina Sánchez¹, Angélica Vargas-Guerrero¹, Luis H Silveira¹ and Manuel Martínez-Lavín³, ¹Instituto Nacional de Cardiología, Ciudad de México, Mexico, ²National Institute of Cardiology Ignacio Chávez, Ciudad de México, Mexico, ³Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, Mexico
Background/Purpose: Allodynia is a key fibromyalgia (FM) feature. Women suffering from FM display more often sphygmomanometry-elicited allodynia when compared to women with osteoarthritis, rheumatoid arthritis…
Abstract Number: 0096 • ACR Convergence 2022
Delayed Referral of Female Rheumatoid Arthritis Patients: Where Are We Now? A Study Spanning Three Decades
Bastiaan van Dijk¹ and Annette van der Helm-van Mil², ¹Leiden University Medical Centre (LUMC), Leiden, Netherlands, ²Leiden University Medical Center, Erasmus Medical Center, Leiden, Netherlands
Background/Purpose: Delayed referral of female RA-patients was reported twenty years ago: the time between the first appointment with the general practitioner (GP) and referral to…
Abstract Number: 1497 • ACR Convergence 2022
How Does Time to Diagnosis and Gender Affect Treatment Outcomes in Patients with Ankylosing Spondylitis or Psoriatic Arthritis? – Real World Data from a German Observational Study with Secukinumab
Karolina Benesova¹, Oliver Hansen², Uta Kiltz³, Jan Brandt-Juergens⁴, Peter Kästner⁵, Elke Riechers⁶, Daniel Peterlik⁷, Christina Budden⁷, Annika Boas⁷, Stefanie Welle⁷ and Hans-Peter Tony⁸, ¹University Hospital Heidelberg, Heidelberg, Germany, ²Medizinische Abteilung V - Rheumatologie, Universitätsklinikum, Heidelberg, Germany, ³Rheumazentrum Ruhrgebiet, Herne, Germany, ⁴Rheumatologische Schwerpunktpraxis, Berlin, Germany, ⁵Ambulantes Rheumazentrum, Medizinisches Versorgungszentrum, Erfurt, Germany, ⁶Medizinische Hochschule Hannover, Hannover, Germany, ⁷Novartis Pharma GmbH, Nürnberg, Germany, ⁸Medizinische Klinik II - Rheumatologie/Immunologie, Universitätsklinikum Würzburg, Würzburg, Germany
Background/Purpose: In both, ankylosing spondylitis (AS) and psoriatic arthritis (PsA), women typically have a longer delay in diagnosis.1,2 There is scientific evidence that prognosis for…
Abstract Number: 0369 • ACR Convergence 2021
High Frequency of Complications in Axial Spondyloarthropathy Pregnancies: Emerging Data from the Ankylosing Spondylitis Registry of Ireland
Sinead Maguire¹, Phil Gallagher² and Finbar (Barry) O'Shea¹, ¹St James's Hospital, Dublin, Ireland, ²St Vincent's Hospital, Dublin, Ireland
Background/Purpose: National registries are excellent sources of data to allow analysis of inflammatory arthritis such as axial spondyloarthropathy (axSpA). Our understanding of axSpA has evolved…
Abstract Number: 0383 • ACR Convergence 2021
Differences Between Male vs. Female Presenting with Back Pain in an Integrated Delivery System
Aniket Kawatkar¹, Esther Yi², Erika Estrada¹, Jose Pio¹, Cecilia Portugal¹, David Yi¹ and Steve Lee³, ¹Kaiser Permanente Southern California, Pasadena, CA, ²Novartis Pharmaceuticals Corporation, Weehawken, NJ, ³Southern California Permanente Medical Group, Fontana, CA
Background/Purpose: Back pain exerts significant economic burden and in its inflammatory form is the main clinical symptom of axial spondylarthritis. We evaluated differences in patient…
Abstract Number: 0406 • ACR Convergence 2021
Gender Differences in Clinical Features and Outcomes of Systemic Sclerosis: Analysis of Reuma.pt/SSc Registry
Raquel Freitas¹, Patrícia Martins², Eduardo Dourado², Tânia Santiago³, Francisca Guimarães⁴, Bruno Fernandes⁵, Salomé Garcia⁶, Beatriz Samões⁷, Ana Pinto⁸, Nuno Gonçalves⁹, Maria Lourenço¹⁰, Emanuel Costa¹¹, Margarida Rocha¹², Maura Couto¹³, Ana Catarina Duarte¹, Filipe Araújo¹⁴, Inês Cordeiro², Fátima Godinho¹, Catarina Resende¹⁵, Maria Joo Salvador¹⁶, Ana Cristina Cordeiro¹ and Maria José Santos¹⁷, ¹Hospital Garcia de Orta, Rheumatology department, Almada, Portugal, ²Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET); Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal, ³Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, ⁴Unidade Local de Saúde do Alto Minho, Rheumatology department, Ponte de Lima, Portugal, ⁵Rheumatology Department, Centro Hospitalar Universitário de São João EPE, Braga, Portugal, ⁶Rheumatology Department, Centro Hospitalar Universitário de São João EPE, Porto, Portugal, ⁷Rheumatology Department, Centro Hospitalar Vila Nova de Gaia, VIla Nova de Gaia, Portugal, ⁸Local Health Unit of Guarda, Portugal, Barcelos, Portugal, ⁹Centro Hospitalar Lisboa Ocidental, Rheumatology Department; Hospital Central do Funchal, Lisboa, Portugal, ¹⁰Hospital Egas Moniz, Barcelos, Portugal, ¹¹Hospital de Braga, Braga, Portugal, ¹²Centro Hospitalar Universitário Lisboa Norte, Rheumatology Department, Faro, Portugal, ¹³Centro Hospitalar Tondela - Viseu, Rheumatology Department, Linda a Velha, Portugal, ¹⁴Hospital de Sant'Ana, Rheumatology and Osteoporosis department, Parede, Portugal, ¹⁵Centro Hospitalar Universitário Lisboa Norte, Rheumatology Department, Lisbon, Portugal, ¹⁶Centro Hospitalar e Universitário de Coimbra, Rheumatology Department, Coimbra, Portugal, ¹⁷Rheumatology Department, Hospital Garcia de Orta, Almada, Portugal
Background/Purpose: Systemic sclerosis (SSc) is a rare connective tissue disease of unknown etiology, with a broad spectrum of clinical and laboratory features. Evidence for the…
Abstract Number: 0578 • ACR Convergence 2021
Hyperinsulinemic Diet and Increased Risk of Female Gout: 2 Prospective Cohort Studies of US Women over 30 Years
Natalie McCormick¹, Chio Yokose², Na Lu³, Amit Joshi¹ and Hyon K. Choi⁴, ¹Massachusetts General Hospital, Boston, MA, ²Massachusetts General Hospital, Waltham, MA, ³Arthritis Research Canada, Vancouver, BC, Canada, ⁴Massachusetts General Hospital, Lexington, MA
Background/Purpose: Gout and the metabolic (insulin resistance) syndrome frequently coexist. Intravenous insulin has been shown to raise serum urate (SU) levels in physiologic studies1 and…
Abstract Number: 0592 • ACR Convergence 2021
Gender Modifies the Effect of Rheumatoid Arthritis on All-Cause Mortality
Srikanta Banerjee¹ and Stephanie Falls², ¹Walden University, Leola, ²PA Department of Health, Leola
Background/Purpose: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease which predominantly affects joints with varying severity. While RA has been found to be…
Abstract Number: 0597 • ACR Convergence 2021
Sex Differences in Multimorbidity Between Patients with Systemic Lupus Erythematosus and Comparators in a Large Nationwide US Study
Ali Duarte-Garcia¹, Herbert Heien¹, Nilay Shah¹ and Cynthia Crowson², ¹Mayo Clinic, Rochester, MN, ²Mayo Clinic, Eyota, MN
Background/Purpose: Patients with systemic lupus erythematosus (SLE) have an increased burden of multimorbidity. Although many comorbidities may vary by sex and men with lupus may…