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Abstracts tagged "gender"

  • Abstract Number: 1101 • ACR Convergence 2022

    Sex and Racial Differences in Systemic Lupus Erythematosus Among U.S. Adults in the All of Us Research Program

    Rachel Elam1, Deepak Ayyala1, Adria Madera-Acosta1, Stephen Bell1, Anam Qureshi1, Christopher Rice2, Laura Carbone1, Steven Coughlin1 and Hong Shi3, 1Augusta University, Augusta, GA, 2Moses H. Cone Memorial Hospital, Augusta, GA, 3Department of Internal Medicine/Division of Rheumatology, Vascular Biology Center, Augusta, GA

    Background/Purpose: Most persons with systemic lupus erythematosus (SLE) are women, and men with SLE are an understudied demographic. The purpose of this study was to…
  • Abstract Number: 1153 • ACR Convergence 2022

    Differentially Expressed Genes in Males and Females with Ankylosing Spondylitis (AS): Transcriptomics of IL-17-producing Cells in Patients with AS

    Chan Mi Lee1, Ricky Chan2, Maricela Haghiac3 and Marina Magrey4, 1University Hospitals, Cleveland, OH, 2Case Western Reserve University, Cleveland, OH, 3Metrohealth Medical Center, Cleveland, OH, 4Case Western Reserve University, University Hospitals, Richfield, OH

    Background/Purpose: Unlike most autoimmune diseases, ankylosing spondylitis (AS) is more frequently diagnosed in men (3:1) and with a higher radiographic progression compared to women. Th17…
  • Abstract Number: 1158 • ACR Convergence 2022

    Differential Plasma Levels of S100 Proteins in Male versus Female Patients with Ankylosing Spondylitis

    Chan Mi Lee1, Maricela Haghiac2 and Marina Magrey3, 1University Hospitals, Cleveland, OH, 2Metrohealth Medical Center, Cleveland, OH, 3Case Western Reserve University, University Hospitals, Richfield, OH

    Background/Purpose: S100 proteins are a family of 25 calcium-binding cytosolic proteins which are involved in stress and inflammatory responses. S100A4 acts as a negative regulator…
  • Abstract Number: 1178 • ACR Convergence 2022

    Key Features of Human Fibrosing Interstitial Lung Disease Are Captured in a Preclinical Mouse Model upon Repetitive, but Not Single Intratracheal Bleomycin Dosing

    David Lauer1, Janine Schniering2, Matthias Brunner1, Chantal Meier3, Kerstin Klein1, Oliver Distler4 and Britta Maurer1, 1Department of Rheumatology and Immunology, University Hospital Bern, University of Bern, Bern, Switzerland, 2Helmholtz Zentrum München, Institute of Lung Health and Immunity (LHI), Comprehensive Pneumonology Center, Munich, Germany, 3Center of Experimental Rheumatology, Department of Rheumatology, University Hospital Zurich, University of Zurich, Schlieren, Switzerland, 4Department of Rheumatology, University Hospital Zurich, University of Zurich, Zürich, Switzerland

    Background/Purpose: Repetitive alveolar epithelial injury together with dysregulated tissue repair is crucial for the transition of acute self-limiting to chronic-persisting inflammation and fibrosis in fibrosing…
  • Abstract Number: 1219 • ACR Convergence 2022

    Gender-Related Clinical Profile of Fibromyalgia Patients

    Mark Berman1, Liane banon2, Omer Shlezinger3, Laurence Mangel4, Jacob Ablin1 and Valerie Aloush5, 1Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 2Department of Gastroenterology and Hepatolgy, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, 3Internal Medicine F, Tel Aviv, Israel, 4Sackler faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 5Tel Aviv Medical Center, Tel Aviv, Israel

    Background/Purpose: Fibromyalgia is a chronic pain disorder characterized by widespread pain, fatigue, sleep disturbances, cognitive dysfunction and frequent psychiatric comorbidities. Estimated prevalence of fibromyalgia is…
  • Abstract Number: 0085 • ACR Convergence 2022

    Closing the Gender Gap in Global Rheumatology Leadership- Are We There Yet?

    Tayyeba Khursheed1, Pavel Ovseiko2, Ghita Harifi3, Humeira Badsha4, Harish G Shekar5 and Latika Gupta6, 1Pakistan Institute of Medical Sciences, Islamabad, Pakistan, 2John Radcliffe Hospital, Oxford, Oxford, United Kingdom, 3Department of Rheumatology, Mediclinic Parkview Hospital, Dubai, United Arab Emirates, 4Dr. Humeira Badsha Medical Center, Dubai, United Arab Emirates, 5Rajarajeswari medical College and hospital, Bangalore, India, 6Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom

    Background/Purpose: The gender equity in academic rheumatology initiative has sparked discussions on the effect of inequity in academia on assignment to leadership roles. To explore…
  • Abstract Number: 1225 • ACR Convergence 2022

    Sphygmomanometry for Fibromyalgia Detection in a Rheumatology Outpatient Clinic. a Cross-sectional Study

    Viridiana Del Río Guerrero1, Laura Aline Martínez Martínez1, Karina Arias Callejas1, Natalia Carbonell-Bobadilla2, Alejandra Mejía Segura1, Gibrán Azamar Morales1, Alejandra Espinosa Orantes1, Mauricio Mora Ramírez1, Fernanda Mejía Ávila1, Raúl Molina Sánchez1, Angélica Vargas-Guerrero1, Luis H Silveira1 and Manuel Martínez-Lavín3, 1Instituto Nacional de Cardiología, Ciudad de México, Mexico, 2National Institute of Cardiology Ignacio Chávez, Ciudad de México, Mexico, 3Instituto Nacional de Cardiología Ignacio Chávez, Ciudad de México, Mexico

    Background/Purpose: Allodynia is a key fibromyalgia (FM) feature. Women suffering from FM display more often sphygmomanometry-elicited allodynia when compared to women with osteoarthritis, rheumatoid arthritis…
  • Abstract Number: 0096 • ACR Convergence 2022

    Delayed Referral of Female Rheumatoid Arthritis Patients: Where Are We Now? A Study Spanning Three Decades

    Bastiaan van Dijk1 and Annette van der Helm-van Mil2, 1Leiden University Medical Centre (LUMC), Leiden, Netherlands, 2Leiden University Medical Center, Erasmus Medical Center, Leiden, Netherlands

    Background/Purpose: Delayed referral of female RA-patients was reported twenty years ago: the time between the first appointment with the general practitioner (GP) and referral to…
  • Abstract Number: 1497 • ACR Convergence 2022

    How Does Time to Diagnosis and Gender Affect Treatment Outcomes in Patients with Ankylosing Spondylitis or Psoriatic Arthritis? – Real World Data from a German Observational Study with Secukinumab

    Karolina Benesova1, Oliver Hansen2, Uta Kiltz3, Jan Brandt-Juergens4, Peter Kästner5, Elke Riechers6, Daniel Peterlik7, Christina Budden7, Annika Boas7, Stefanie Welle7 and Hans-Peter Tony8, 1University Hospital Heidelberg, Heidelberg, Germany, 2Medizinische Abteilung V - Rheumatologie, Universitätsklinikum, Heidelberg, Germany, 3Rheumazentrum Ruhrgebiet, Herne, Germany, 4Rheumatologische Schwerpunktpraxis, Berlin, Germany, 5Ambulantes Rheumazentrum, Medizinisches Versorgungszentrum, Erfurt, Germany, 6Medizinische Hochschule Hannover, Hannover, Germany, 7Novartis Pharma GmbH, Nürnberg, Germany, 8Medizinische Klinik II - Rheumatologie/Immunologie, Universitätsklinikum Würzburg, Würzburg, Germany

    Background/Purpose: In both, ankylosing spondylitis (AS) and psoriatic arthritis (PsA), women typically have a longer delay in diagnosis.1,2 There is scientific evidence that prognosis for…
  • Abstract Number: 0369 • ACR Convergence 2021

    High Frequency of Complications in Axial Spondyloarthropathy Pregnancies: Emerging Data from the Ankylosing Spondylitis Registry of Ireland

    Sinead Maguire1, Phil Gallagher2 and Finbar (Barry) O'Shea1, 1St James's Hospital, Dublin, Ireland, 2St Vincent's Hospital, Dublin, Ireland

    Background/Purpose: National registries are excellent sources of data to allow analysis of inflammatory arthritis such as axial spondyloarthropathy (axSpA). Our understanding of axSpA has evolved…
  • Abstract Number: 0383 • ACR Convergence 2021

    Differences Between Male vs. Female Presenting with Back Pain in an Integrated Delivery System

    Aniket Kawatkar1, Esther Yi2, Erika Estrada1, Jose Pio1, Cecilia Portugal1, David Yi1 and Steve Lee3, 1Kaiser Permanente Southern California, Pasadena, CA, 2Novartis Pharmaceuticals Corporation, Weehawken, NJ, 3Southern California Permanente Medical Group, Fontana, CA

    Background/Purpose: Back pain exerts significant economic burden and in its inflammatory form is the main clinical symptom of axial spondylarthritis. We evaluated differences in patient…
  • Abstract Number: 0406 • ACR Convergence 2021

    Gender Differences in Clinical Features and Outcomes of Systemic Sclerosis: Analysis of Reuma.pt/SSc Registry

    Raquel Freitas1, Patrícia Martins2, Eduardo Dourado2, Tânia Santiago3, Francisca Guimarães4, Bruno Fernandes5, Salomé Garcia6, Beatriz Samões7, Ana Pinto8, Nuno Gonçalves9, Maria Lourenço10, Emanuel Costa11, Margarida Rocha12, Maura Couto13, Ana Catarina Duarte1, Filipe Araújo14, Inês Cordeiro2, Fátima Godinho1, Catarina Resende15, Maria Joo Salvador16, Ana Cristina Cordeiro1 and Maria José Santos17, 1Hospital Garcia de Orta, Rheumatology department, Almada, Portugal, 2Rheumatology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon Academic Medical Centre and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET); Rheumatology Research Unit, Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal, 3Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, 4Unidade Local de Saúde do Alto Minho, Rheumatology department, Ponte de Lima, Portugal, 5Rheumatology Department, Centro Hospitalar Universitário de São João EPE, Braga, Portugal, 6Rheumatology Department, Centro Hospitalar Universitário de São João EPE, Porto, Portugal, 7Rheumatology Department, Centro Hospitalar Vila Nova de Gaia, VIla Nova de Gaia, Portugal, 8Local Health Unit of Guarda, Portugal, Barcelos, Portugal, 9Centro Hospitalar Lisboa Ocidental, Rheumatology Department; Hospital Central do Funchal, Lisboa, Portugal, 10Hospital Egas Moniz, Barcelos, Portugal, 11Hospital de Braga, Braga, Portugal, 12Centro Hospitalar Universitário Lisboa Norte, Rheumatology Department, Faro, Portugal, 13Centro Hospitalar Tondela - Viseu, Rheumatology Department, Linda a Velha, Portugal, 14Hospital de Sant'Ana, Rheumatology and Osteoporosis department, Parede, Portugal, 15Centro Hospitalar Universitário Lisboa Norte, Rheumatology Department, Lisbon, Portugal, 16Centro Hospitalar e Universitário de Coimbra, Rheumatology Department, Coimbra, Portugal, 17Rheumatology Department, Hospital Garcia de Orta, Almada, Portugal

    Background/Purpose: Systemic sclerosis (SSc) is a rare connective tissue disease of unknown etiology, with a broad spectrum of clinical and laboratory features. Evidence for the…
  • Abstract Number: 0578 • ACR Convergence 2021

    Hyperinsulinemic Diet and Increased Risk of Female Gout: 2 Prospective Cohort Studies of US Women over 30 Years

    Natalie McCormick1, Chio Yokose2, Na Lu3, Amit Joshi1 and Hyon K. Choi4, 1Massachusetts General Hospital, Boston, MA, 2Massachusetts General Hospital, Waltham, MA, 3Arthritis Research Canada, Vancouver, BC, Canada, 4Massachusetts General Hospital, Lexington, MA

    Background/Purpose: Gout and the metabolic (insulin resistance) syndrome frequently coexist. Intravenous insulin has been shown to raise serum urate (SU) levels in physiologic studies1 and…
  • Abstract Number: 0592 • ACR Convergence 2021

    Gender Modifies the Effect of Rheumatoid Arthritis on All-Cause Mortality

    Srikanta Banerjee1 and Stephanie Falls2, 1Walden University, Leola, 2PA Department of Health, Leola

    Background/Purpose: Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease which predominantly affects joints with varying severity. While RA has been found to be…
  • Abstract Number: 0597 • ACR Convergence 2021

    Sex Differences in Multimorbidity Between Patients with Systemic Lupus Erythematosus and Comparators in a Large Nationwide US Study

    Ali Duarte-Garcia1, Herbert Heien1, Nilay Shah1 and Cynthia Crowson2, 1Mayo Clinic, Rochester, MN, 2Mayo Clinic, Eyota, MN

    Background/Purpose: Patients with systemic lupus erythematosus (SLE) have an increased burden of multimorbidity. Although many comorbidities may vary by sex and men with lupus may…
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