Abstracts tagged "Fracture"

Abstract Number: 0341 • ACR Convergence 2025
Romosozumab in patients with Osteoporosis: Safety and Efficacy analysis in Clinical Practice
Daniel Ramos Castro¹, SAMUEL LEAL², ELENA GRAU GARCIA³, Pablo Muñoz-Martínez⁴, Laura Mas Sanchez⁵, Alba Maria Torrat Noves⁶, Belen Villanueva Manes⁷, Iago Alcántara Álvarez⁸, Andres perez Hurtado⁹, Miguel Simeo Vinaixa⁹ and José Andrés Román Ivorra¹⁰, ¹Hospital Universitari i Politecnic La Fe, Valencia, Spain, ²Rheumatology Department. HUP La Fe, Valencia, Comunidad Valenciana, Spain, ³HUP La Fe, Valencia, Comunidad Valenciana, Spain, ⁴Hospital Universitario y Politécnico La Fe, Sagunto, Spain, ⁵Hospital Universitari i Politecnic La Fe, València, Spain, ⁶Hospital Universitari i Politècnic La Fe de Valencia, Valencia, Spain, ⁷Hospital La Fe, València, Spain, ⁸Hospital Universitari i Politénic La Fe, València, Spain, ⁹Rheumatology Department. HUP La Fe, Valencia, Spain, ¹⁰Hospital Universitari i Politècnic La Fe, Valencia, Spain
Background/Purpose: Osteoporosis is the most common bone metabolism disorder in developed countries. It increases the risk of fragility fractures, impairing quality of life, increasing disability,…
Abstract Number: 2107 • ACR Convergence 2025
Experience of a Fragility Fracture Coordination Unit Integrated Across Two Hospitals: An Innovative Multidisciplinary Model for Optimizing the Management of Geriatric and Non-Geriatric Patients Beyond Surgery After an Osteoporotic Bone Fragility Fracture
César Antonio Egües Dubuc¹, Esther Laso Lucas², Nerea Alcorta Lorenzo³, Carlos Maria Lizasoain Alustiza⁴, Leire Unanue Pumar⁴, Gabriela Jimenez Clemente², Claudia Murillo Erazo², Vicente Lavilla Garcia², Ander Alberdi Arbelaiz⁴, Elena Zubillaga Azpiroz⁴, Imanol Gabarain Morcillo⁴, Jorge Jesus Cancio Fanlo⁵, Maria Ariztia Sarratea², Iñaki Maria Arruabarrena Echeverria⁴, Gaspar de La Herran Nuñez⁴, Antonio Martin Garcia⁴ and LUIS LOPEZ DOMINGUEZ⁶, ¹Donostia University Hospital, San Sebastián, Pais Vasco, Spain, ²Matia Hospital, San Sebastian, Pais Vasco, Spain, ³University Hospital Donostia, san sebastian, Spain, ⁴Donostia University Hospital, San Sebastian, Pais Vasco, Spain, ⁵Donostia University Hospital, San Sebastian, ⁶Hospital Universitario Donostia, San Sebastian, Spain
Background/Purpose: Fracture Coordination Units typically function within a single hospital using a multidisciplinary approach. Our unit, established in February 2024, pioneers a model coordinating care…
Abstract Number: 0340 • ACR Convergence 2025
Associations with fragility fractures in a population with inflammatory bowel disease (IBD): An observational study.
Chern Lee Choy¹, Hamzah Amin² and marwan Bukhari³, ¹University Hospitals of Morecambe Bay NHS Foundation Trust, Barrow-In-Furness, United Kingdom, ²Lancaster University, Lancaster, United Kingdom, ³University Hospitals of Morecambe bay NHS foundation trust, Lancaster, United Kingdom
Background/Purpose: It is well recognized that inflammatory bowel disease (IBD) is associated with osteoporosis and fragility fractures, likely due to multiple factors, including systemic inflammation,…
Abstract Number: 2106 • ACR Convergence 2025
Prevalence and Characteristics of Morphometric Vertebral Fractures in the Spanish Population: Data from the OsteoSER Study
Carmen Gomez Vaquero¹, Montserrat Roig Kim², Jordi Fiter Areste³, Marta Domínguez-Álvaro⁴, Luis María Jiménez Liñán⁵, Miguel Bernad⁶, Antonio Álvarez-Cienfuegos⁷, Blanca Correa⁸, Antonio Pascual-Vergara⁹, Alejandra Montero Costa¹⁰, Cristina Momblan Trejo¹¹, Manuel Jiménez Rodríguez¹², María Anadón González¹³, Sara Josefina Barcat Zarate¹⁴, Sara Alvar Pariente¹⁵, Cristina Ruiz Pavón¹⁶, Pedro J. Lacalle Chanivet¹⁷, Balbina Marín de Prada¹⁸, Soledad García Frías¹⁹, Francisco Javier Maestro Saavedra²⁰, Marta Poch i Mora²¹, José Luis Gea González²², Carlota Quiroga Fernández²³, Eduardo Acevedo Martel²⁴ and Enrique González-Dávila²⁵, ¹Hospital Universitari de Bellvitge, ⁰⁸⁹⁰⁷ L'Hospitalet, Spain, ²Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, ³Hospital Universitari Son Espases, Palma de Mallorca, Spain, ⁴Sociedad Española de Reumatología, Madrid, Spain, ⁵Hospital Don Benito-Villanueva, Don Benito, Spain, ⁶Hospital Universitario La Paz, Madrid, Spain, ⁷Hospital Vega Baja, Orihuela, Spain, ⁸Clínica Sanz y Correa, A Coruña, Spain, ⁹Centro de Salud Ronda-Norte y Ronda-Sur, Ronda, Spain, ¹⁰Centro de Salud Fuencarral, Madrid, Spain, ¹¹Centro de Atención Primaria Viladecans Montbaig, Sant Climent de Llobregat, Spain, ¹²Centro de Salud Don Benito Oeste, Don Benito, Spain, ¹³Consultorio de Pedrezuela, Pedrezuela, Spain, ¹⁴Centro de Salud Orihuela ¹-El Rabaloche, Orihuela, Spain, ¹⁵Centro de Salud Malpica, Malpica, Spain, ¹⁶Centro de Salud Ronda-Norte, Ronda, Spain, ¹⁷Centro de Salud de Santa Amalia, Santa Amalia, Spain, ¹⁸Centro de Atención Primaria Ramona Via i Pros, El Prat de Llobregat, Spain, ¹⁹Centro de Salud de Cortes de la Frontera, Cortes de la Frontera, Spain, ²⁰Centro de Salud Elviña Mesoiro, A Coruña, Spain, ²¹Centro de Atención Primaria CAP ¹⁷ de Setembre, El Prat de Llobregat, Spain, ²²Centro de Salud de Benejúzar, Benezujar, Spain, ²³Centro de Salud Os Mallos, A Coruña, Spain, ²⁴Centro de Salud Ronda-Sur Santa Bárbara, Ronda, Spain, ²⁵Departamento de Matemáticas. Universidad de La Laguna, Tenerife, Spain
Background/Purpose: Most vertebral fractures (VFs) are asymptomatic. Vertebral Fracture Assessment (VFA) using DXA is a low-radiation method to detect morphometric vertebral fractures (MVFs). This study…
Abstract Number: 0246 • ACR Convergence 2025
Fracture Risk in Intestinal Autoimmune-mediated Diseases Patients: Clinical Insights from REMS
Marco Di Paola¹, Fiorella Anna Lombardi¹, Edmund J MacLaughlin², Maurizio Muratore³, Kathleen Methric⁴, Gianmarco Del Vecchio⁵, Giusy Peluso⁶, Chiara Stomaci⁷, Roberto Franchini¹, Francesco Conversano¹, Paola Pisani¹ and Sergio Casciaro¹, ¹Institute of Clinical Physiology, National Research Council, Lecce, Puglia, Italy, ²Rheumatology Associates of Delmarva and BoneVue Diagnostics, Easton, MD, ³ASL- LE, "Vito Fazzi" Hospital, Lecce, Puglia, Italy, ⁴BoneVue Diagnostics, Catonsville, MD, ⁵Department of Research and Development, Echolight S.p.a., Lecce, Puglia, Italy, ⁶Department of Innovative Engineering, University of Salento, Lecce, Puglia, Italy, ⁷Department of Biological and Envinronmental Sciences and Technologies, University of Salento, Lecce, Puglia, Italy
Background/Purpose: Intestinal Bowel Diseases (IBD), including Crohn’s (ChD), and Ulcerative Colitis (UCD), along with Celiac (ClD), diseases are chronic inflammatory conditions that primarily affect the…
Abstract Number: 2070 • ACR Convergence 2025
Characterization of Hospitalization, Patient Demographics and Impact of Idiopathic Inflammatory Myopathies on Hospitalization Outcomes in Adult Fracture Patients: A National Inpatient Sample Analysis.
Pranathi Bandarupalli¹, Vineeth Potluri², Amr Alemairy², Harsharn Grewal² and Shudipan Chakraborthy², ¹Mercy St Vincent Medical Center, Toledo, OH, ²Mercy Health St. Vincent Medical Center, Toledo, OH
Background/Purpose: Idiopathic Inflammatory Myopathies (IIM), including polymyositis and dermatomyositis, are rare systemic autoimmune disorders characterized by chronic muscle inflammation and progressive muscle weakness. Patients with…
Abstract Number: 2115 • ACR Convergence 2025
METHOFRACT, a methotrexate osteopathy multicentric binational cohort study.
François ROBIN¹, Roba Ghossan², Nadia Mehsen-Cetre³, Louise Triquet¹, Guillaume LARID⁴, Guillaume Coiffier⁵, Marine Mina⁶, Marie-Eva Pickering⁷, Claire Barthe⁸, Julien Paccou⁹, Julien Herman¹⁰, Emmanuel Massy¹¹, Isabelle Roitg¹², Martine Branquet¹³, Julien Lasnier Siron³, Manon Guillouard¹⁴, Camille Desmonet Trousset¹⁵, Aurore Aubrun¹⁶, Bertrand Godfrin¹⁷, Jean-Philippe Hauzeur¹⁸, Emmanuel Chatelus¹⁹, Eugénie Koumakis², Jean-Louis Legrand²⁰, Thierry Schaeverbeke³, Alexia Leloix¹, Maeva Masson²¹, Julia Nicolau¹⁵, Charles Ghiringhelli²², Marijke Decrock¹², Durel Cécile-Audrey²³, Béatrice Bouvard²⁴, Bernard Cortet⁹, Charlotte Casadepax-Soulet²⁵, Olivier Malaise⁶, Rose Marie Javier²⁶, Karine Briot² and Pascal Guggenbuhl¹, ¹Rennes University Hospital, Rennes, France, ²APHP, Paris, France, ³Bordeaux University Hospital, Bordeaux, France, ⁴Poitiers University Hospital - Poitiers University - LITEC Laboratory UR ¹⁵⁵⁶⁰, Poitiers, France, ⁵Dinan Hospital, Dinan, France, ⁶Liege University Hospital, Liège, Belgium, ⁷Clermon-Ferrand University Hospital, Clermont-Ferrand, France, ⁸Clinique Tivoli Ducos, Bordeaux, France, ⁹Lille University Hospital, Lille, France, ¹⁰La Roche Sur Yon Hospital, La Roche-sur-Yon, France, ¹¹Lyon University Hospital, Lyon, France, ¹²Perpignan Hospital, Perpignan, France, ¹³Ploemeur Rheumatology Liberal Structure, Ploemeur, France, ¹⁴Aurillac Hospital, Aurillac, France, ¹⁵Dieppe Hospital, Dieppe, France, ¹⁶Nice Rheumatology Liberal Stucture, Nice, France, ¹⁷St Gaudens Rheumatology Liberal Structure, St Gaudens, France, ¹⁸Liege University Hospital, Liege, Belgium, ¹⁹Department of Rheumatology, University Hospital Strasbourg, France, Strasbourg, France, ²⁰Arras Hospital, Arras, France, ²¹Toulouse University Hospital, Toulouse, France, ²²Pauillac Rheumatology Liberal Structure, Pauillac, France, ²³Saint Joseph Saint Luc Hospital, Lyon, France, ²⁴Angers University Hospital, Angers, France, ²⁵West Reunion Hospital, Saint Paul, France, ²⁶Strasbourg University Hospital, Strasbourg, France
Background/Purpose: Methotrexate-induced osteopathy is a rare condition. The clinical presentation is often typical, associating lower limb involvement with metaphyseal bone fractures/cracks, mainly of the tibia…
Abstract Number: 1997 • ACR Convergence 2025
Bone health in patients with gout using real-world U.S. data
Emily Holladay¹, Alexis Woods², Fenglong Xie³, Jingyi Zhang¹, Angelo Gaffo⁴, Jeffrey Curtis⁵ and Brian Lamoreaux⁶, ¹University of Alabama at Birmingham, Birmingham, AL, ²Amgen, Detroit, MI, ³The University of Alabama at Birmingham, Birmingham, AL, ⁴Division of Rheumatology and Clinical Immunology, University of Alabama, Birmingham, AL, USA; Birmingham VA Medical Center, Birmingham, AL, USA, Birmingham, AL, ⁵Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL, ⁶Amgen, Inc., Deerfield, IL
Background/Purpose: Patients with gout may be at high risk for developing osteoporosis and fractures, but osteoporosis may be under-recognized and inadequately managed for gout patients.…
Abstract Number: 2114 • ACR Convergence 2025
Development of a Fracture Prediction Model for Patients Aging with HIV
Evelyn Hsieh¹, Terrence E. Murphy², Baylah Tessier-Sherman³, Linda Leo-Summers³, Farah Kidwai-Khan⁴, Samah Fodeh⁵, Rixin Wang⁶, Barbara Gulanski³, Michael T. Yin⁷, Melissa Skanderson⁸, Cynthia Brandt⁹, Amy C. Justice⁴ and Julie Womack¹⁰, ¹Section of Rheumatology, Allergy and Immunology, Yale School of Medicine / VA Connecticut Healthcare System, New Haven, CT, ²Department of Public Health Sciences, Pennsylvania State University College of Medicine, Hershey, PA, ³Department of Internal Medicine, Yale School of Medicine, New Haven, CT, ⁴Department of Internal Medicine, Yale School of Medicine / VA Connecticut Healthcare System, New Haven, CT, ⁵Department of Emergency Medicine, Yale School of Medicine, New Haven, CT, ⁶Department of Biomedical Informatics & Data Science, Yale School of Medicine, New Haven, CT, ⁷Columbia University Irving Medical Center, New York, NY, ⁸VA Connecticut Healthcare System, West Haven, CT, ⁹Department of Biomedical Informatics & Data Science, Yale School of Medicine / VA Connecticut Healthcare System, New Haven, CT, ¹⁰Yale School of Nursing / VA Connecticut Healthcare System, Orange, CT
Background/Purpose: Fragility fractures are a critical outcome for people ageing with HIV (PAH). Studies demonstrate higher prevalence, incidence, and earlier onset than for the general…
Abstract Number: 1727 • ACR Convergence 2025
Distribution of Fracture Risk Status and Osteoporosis Treatment Use Among Postmenopausal Women with Osteoporosis in the United States
Hsu-Chih Chien, Min Kim, Michele McDermott, Mary Oates, Xiaodong Li and Lara Yoon, Amgen Inc, Thousand Oaks, CA
Background/Purpose: Current guidelines recommend treating women with postmenopausal osteoporosis (PMO) based on fracture risk. Anabolic therapy (AT), the RANKL inhibitor denosumab (Dmab), and intravenous zoledronic…
Abstract Number: 1352 • ACR Convergence 2025
Prediction of 5-Year Fracture Risk in Rheumatoid and Psoriatic Arthritis Using REMS Technology
Marco Di Paola¹, Edmund J MacLaughlin², Kathleen Methric³, Maurizio Muratore⁴, Gianmarco Del Vecchio⁵, Giusy Peluso⁶, Ernesto Casciaro¹, Fabiola Rosa Contaldo⁷, Fiorella Anna Lombardi¹, Paola Pisani¹, Francesco Conversano¹ and Sergio Casciaro¹, ¹Institute of Clinical Physiology, National Research Council, Lecce, Puglia, Italy, ²Rheumatology Associates of Delmarva and BoneVue Diagnostics, Easton, MD, ³BoneVue Diagnostics, Catonsville, MD, ⁴ASL- LE, "Vito Fazzi" Hospital, Lecce, Puglia, Italy, ⁵Department of Research and Development, Echolight S.p.a., Lecce, Puglia, Italy, ⁶Department of Innovative Engineering, University of Salento, Lecce, Puglia, Italy, ⁷Department of Biological and Environmental Sciences and Technologies, University of Salento, University of Salento, Lecce, Puglia, Italy
Background/Purpose: Autoimmune arthritis, including Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PA), are among the most common forms of inflammatory joint diseases. These conditions affect joints…
Abstract Number: 1313 • ACR Convergence 2025
Retrospective Analysis of Factors Associated With Fracture in 2855 Patients With Rheumatoid Arthritis, Stratified by Steroid Use
Jonathan Barnes¹, Hamzah Amin² and marwan Bukhari³, ¹Morecambe Bay NHS Trust, Lancaster, United Kingdom, ²Lancaster University, Lancaster, United Kingdom, ³University Hospitals of Morecambe bay NHS foundation trust, Lancaster, United Kingdom
Background/Purpose: Steroids are used in a proportion of patients with rheumatoid arthritis (RA). Steroids are known to cause a decrease in bone mineral density (BMD),…
Abstract Number: 0867 • ACR Convergence 2025
NLRP3 Inflammasome Impairs Fracture Repair in Rheumatoid Arthritis through RhoA/Rac1-IL1β Axis-Mediated Suppression of Osteoblast Differentiation
Wen Sun and Hua Wang, Nanjing Medical University, Nanjing, China (People's Republic)
Background/Purpose: Rheumatoid arthritis (RA) is often characterized by bone loss and fragility fractures and is a frequent comorbidity. The NLRP3 inflammasome, a key mediator of…
Abstract Number: 2120 • ACR Convergence 2024
EvaluationofBone Mineral Densityand Trabecular Bone Score in JuvenileSystemicLupusErythematosusPatientsUsing Dual-Energy X-rayAbsorptiometry
BEATRIZ ROSA¹, Melissa Fraga¹, Erica Barbosa¹, Jade Dib Fernandez², Marcelo Pinheiro³ and Maria Teresa Terreri⁴, ¹Universidade Federal de São Paulo, São Paulo, SP, Brazil, ²UNIFESP-EPM, São Paulo, SP, Brazil, ³UNIFESP/ EPM, São Paulo, SP, Brazil, ⁴UNIFESP, São Paulo, SP, Brazil
Background/Purpose: Juvenile Systemic Lupus Erythematosus (jSLE) is a multisystem inflammatory disease associated with bone mass loss. This loss can be evaluated by using the bone…
Abstract Number: 2121 • ACR Convergence 2024
Increased Fracture Rates in Patients Continuing Methotrexate After Methotrexate-associated Lower Limb Insufficiency Fractures: A Retrospective Follow-up Study
Roba Ghossan¹, OLIVIER FOGEL², Christian Roux¹ and Karine Briot¹, ¹COCHIN HOSPITAL, PARIS, France, ²AP-HP, Paris, France
Background/Purpose: Spontaneous lower limb insufficiency fractures (LLIF) described under prolonged exposure to low-dose methotrexate are often bilateral, multiple, and recurrent. They share a common pathognomonic…

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