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Abstracts tagged "Fracture"

  • Abstract Number: L01 • ACR Convergence 2022

    Impact of Glucocorticoid Dosing and Anti-Osteoporotic Treatment on Bone Health in Patients with Inflammatory Rheumatic Musculoskeletal Diseases: A Longitudinal Cohort Study

    Giovanni Adami, Angelo Fassio, Davide Bertelle, Camilla Benini, Davide Gatti and Maurizio Rossini, Rheumatology Unit, University of Verona, Verona, Italy

    Background/Purpose: The recently published GLORIA (Glucocorticoid LOw-dose in RheumatoId Arthritis) trial has opened the debate around the benefits of glucocorticoids (GCs) in older patients with…
  • Abstract Number: 0262 • ACR Convergence 2022

    Predictors of Fragility Fracture Amongst Patients with Rheumatoid Arthritis: An Observational Cohort Study

    Seema Sharma1 and Marwan Bukhari2, 1Lancaster Royal Infirmary, Lancaster, United Kingdom, 2University Hospitals of Morecambe Bay NHS Trust, Lancaster, United Kingdom

    Background/Purpose: Rheumatoid arthritis (RA) is associated with reduced bone mineral density and almost one third of this population have osteoporosis leading to increased risk of…
  • Abstract Number: 1323 • ACR Convergence 2022

    Secondary Prevention of Vertebral Fractures Sustained Efficacy over Time

    JOSE ELOY OLLER RODRIGUEZ1, Elena Grau García2, Samuel Leal Rodriguez3, Laura Mas Sanchez2, Pablo Francisco Muñoz Martínez4, Carmen Riesco Bárcena5, Anderson Huaylla Quispe6, Cristobal Pavez Perales2, Francisco Miguel Ortiz Sanjuan7, José Ivorra Cortés2, Inés Cánovas Olmos2, Luis González Puig8, Isabel Martínez-Cordellat2, Carmen Nájera Herranz7, Rosa Negueroles Albuixech2, Elvira Vicens Bernabeu7, Alba Torrat Novés5, Daniel Ramos Castro2 and José andrés Román ivorra3, 1Hospital Universitario de La Fe, València, Spain, 2Rheumatology Department. Hospital Universitario y Politécnico La Fe, València, Spain, 3Hospital Universitari i Politécnic La Fe, València, Spain, 4Hospital Universitario y Politécnico La Fe, València, Spain, 5Rheumatology Department. Hospital Universitario y Politécnico La Fe, València, 6Medicina, València, Spain, 7Hospital Universitario de La Fe, València, 8Rheumatology Department. Hospital Universitario y Politécnico La Fe, Torrente, Valencia, Spain

    Background/Purpose: Vertebral fractures entail a notorious social and health problem, and their presence is the greatest risk factor for the appearance of a new vertebral…
  • Abstract Number: 0388 • ACR Convergence 2022

    Incidence Rate and Factors Associated with Fractures Among Older Adults with Ankylosing Spondylitis in the United States

    Rachael Stovall1, Emma Kersey1, Jing Li2, Rahaf Baker3, Christine Anastasiou2, Gabriela Schmajuk4, Lianne Gensler5 and Jinoos Yazdany6, 1University of California San Francisco, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA, 3Alameda Highland Internal Medicine Residency, Oakland, CA, 4UCSF / SFVA, San Francisco, CA, 5Department of Medicine, Division of Rheumatology, University of California San Francisco, San Francisco, CA, 6UCSF, San Francisco, CA

    Background/Purpose: Adults with ankylosing spondylitis (AS) are at a significantly increased risk of fracture relative to the general population. While some studies have evaluated the…
  • Abstract Number: 1327 • ACR Convergence 2022

    Immune Cell Subsets and Risk of Incident Hip Fracture in Older Adults: The Cardiovascular Health Study

    Rachel Elam1, Petra Buzkova2, Joseph Delaney3, Howard Fink4, Joshua Barzilay5, Laura Carbone1, Rick Saha1, John Robbins6, Kenneth Mukamal7, Rodrigo Valderrabano8, Bruce Psaty2, Russell Tracy9, Nels Olson9, Sally Huber10, Margaret Doyle9, Alan Landay11 and Jane Cauley12, 1Augusta University, Augusta, GA, 2University of Washington, Seattle, WA, 3University of Manitoba, Winnipeg, MB, Canada, 4University of Minnesota, Minneapolis, MN, 5Kaiser Permanente, Atlanta, GA, 6UC Davis, Davis, CA, 7Beth Israel Deaconess Medical Center, Boston, MA, 8Brigham and Women's Hospital, Boston, MA, 9University of Vermont, Burlington, VT, 10University of Vermont, Burlingon, VT, 11Rush University Medical Center, Chicago, IL, 12University of Pittsburgh, PIttsburgh, PA

    Background/Purpose: Cell-mediated immunity may play a role in osteoporosis development. Fracture is the major consequence of osteoporosis. Thus, cell-mediated immunity may impact fracture risk. We…
  • Abstract Number: 0502 • ACR Convergence 2022

    The Effect of Osteoporosis on Developing Vertebral Compression Fracture After Single-level Posterior Lumbar Fusion Surgery: A Large Healthcare Claims Database Study

    Vartika Kesarwani1, Sean Esmende2, Regina Kostyun2, Matthew Solomito2, Heeren Makanji2, John Magaldi2 and Mandeep Kumar2, 1University of Connecticut, Farmington, CT, 2Bone and Joint Institute, Hartford Hospital, Hartford, CT

    Background/Purpose: Vertebral compression fracture (VCF) is a significant osteoporosis-related complication (ORC) associated with instrumented spinal fusion. Various studies have assessed the development of VCF in…
  • Abstract Number: 1330 • ACR Convergence 2022

    Impact of COVID-19 Severity on Physical Function, Mobility, Falls and Fractures Among Older Patients After Hospitalization: A Longitudinal Study

    Clara Wong1, Diego Cabrera2, Mary Geda3, Andrew Cohen3, Lauren Ferrante3, Alexandra Hajduk3 and Evelyn Hsieh2, 1Yale School of Public Health, New Haven, CT, 2Section of Rheumatology, Allergy and Immunology, Yale School of Medicine, New Haven, CT, 3Yale School of Medicine, New Haven, CT

    Background/Purpose: No longitudinal studies have examined the impact of COVID-19 or COVID-19 severity on physical function and disability outcomes among older adults. Multiple factors, including…
  • Abstract Number: 0503 • ACR Convergence 2022

    The Effect of Social Isolation on 1-Year Outcomes After Surgical Repair of Low Trauma Hip Fracture

    Robyn Lipschultz1, Dina Sheira1, Marianna Frey2, Mangala Rajan3, Joseph Lane1 and Lisa Mandl1, 1Hospital for Special Surgery, New York, NY, 2University of Rochester School of Medicine and Dentistry, New York, NY, 3Weill Cornell Medicine, New York, NY

    Background/Purpose: Hip fractures are a serious public health issue with a significant population burden, especially among those over 65 years old. Social isolation—how integrated a…
  • Abstract Number: 1331 • ACR Convergence 2022

    Risk Factors for Osteoporotic Fracture in Women with Established Long-Term Rheumatoid Arthritis

    Felipe Freire da Silva1, Gisela Machado2, ana Medeiros3, Karina Bonfiglioli4, Andrea Shimabuco2, Liliam Takayama5, Rosa Pereira6 and Diogo Domiciano7, 1FMUSP, Salvador, Brazil, 2FMUSP, São Paulo, Brazil, 3Faculdade de Medicina da Universidade de São Paulo, São Jose Dos Campos, Brazil, 4Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 5University of São Paulo, São Paulo, Brazil, 6Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 7Hospital das Clinicas, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Low bone mineral density (BMD) is a predictor of osteoporotic fracture. However, individuals with Rheumatoid Arthritis (RA) who sustain "osteoporosis-related" fractures frequently have normal…
  • Abstract Number: 0574 • ACR Convergence 2022

    Osteoporosis in Elderly Men; An Underestimated and Underdiagnosed Morbid Entity

    Arash Mollaeian1 and Stanley Ballou2, 1Metro Health Medical Center/Case Western Reserve University, Rocky River, OH, 2Case Western Reserve University - Metro Health, Cleveland, OH

    Background/Purpose: 20-25% of osteoporosis-related fractures occur in men and the mortality of osteoporotic fractures is higher in men [1]. Nevertheless, no uniform consensus exists for…
  • Abstract Number: 1431 • ACR Convergence 2022

    Impact of Tofacitinib on Fracture Risk in Rheumatoid Arthritis

    Karen E Hansen1, Mahta Mortezavi2, Edward Nagy3, Cunshan Wang4, Carol A Connell4, Zaher Radi5, Heather J Litman6, Giovanni Adami7 and Maurizio Rossini7, 1Rheumatology Division, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI, 2Pfizer Inc, New York, NY, 3Pfizer Ltd, Tadworth, United Kingdom, 4Pfizer Inc, Groton, CT, 5Pfizer Inc., Cambridge, MA, 6CorEvitas, LLC, Waltham, MA, 7Rheumatology Unit, Department of Medicine, University of Verona, Verona, Italy

    Background/Purpose: Preclinical data suggest that tofacitinib stimulates osteoblast function and would have a protective effect on bone health and fracture risk in RA.1 We report…
  • Abstract Number: 0576 • ACR Convergence 2022

    Comparative Effectiveness of Osteoporosis (OP) Therapies Among a Population of Postmenopausal (PM) Women in the United States (U.S.)

    Min Kim1, Leah J McGrath2, David Pritchard2, Peter Samai2, Jay Lin1, Robert Kees Stad3, Leslie Spangler1, Michele McDermott1, Brian D Bradbury4 and M Alan Brookhart2, 1Amgen, Inc., Thousand Oaks, CA, 2NoviSci, Inc., Durham, NC, 3Amgen Inc., Zug, Switzerland, 4Amgen Inc., 1 Amgen Center Drive

    Background/Purpose: Although clinical trials evaluating the efficacy of osteoporosis (OP) therapies have shown that denosumab (Dmab) significantly increases bone mineral density at pivotal sites compared…
  • Abstract Number: 1477 • ACR Convergence 2022

    Prevalence and Risk Factors of Fragility Fractures in Systemic Lupus Erythematosus: A Longitudinal Study over 12 Years

    Chi Chiu Mok1, Kar Li Chan2, Ling Yin Ho3 and Chi Hung To4, 1Tuen Mun Hospital, Hong Kong, China, 2Tuen Mun Hospital, Tsing Yi, Hong Kong, China, 3Tuen Mun Hospital, Hong Kong SAR, China, 4Hospital Authority, Hong Kong, Hong Kong

    Background/Purpose: To study the prevalence and risk factors of fragility fractures in a longitudinal cohort of patients with SLE.Methods: All patients who fulfilled ≥4 1997…
  • Abstract Number: 0577 • ACR Convergence 2022

    Bone Mineral Density of Radius 1/3 Led to a Better Fracture Prediction When Combined with Spine but Not Hip BMD: Results from the São Paulo Ageing & Health (SPAH) Study

    Diogo Domiciano1, Luana Machado2, Valeria Caparbo3, Carolina Teixeira Cidon4, Thais Helena Bonini Gorayeb4, Maria Aurora Gomes da SIlva5, ricardo Manoel de oliveira6, camille figueiredo3 and Rosa Pereira3, 1Hospital das Clinicas, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Hospital das Clinicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 3Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Hospital das Clínicas, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 5Bone Metabolism Laboratory, Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, 6RDO Diagnósticos Médicos, São Paulo, Brazil

    Background/Purpose: Bone mineral density (BMD) of the spine or hip are predictors of osteoporotic fracture, but individuals who sustain "osteoporosis-related" fractures frequently have normal BMD…
  • Abstract Number: 0727 • ACR Convergence 2022

    Primary Prevention of Fractures in Osteoporotic Patients in a Southern California Academic Health System

    Eugene Looi1, Gergana Mishkova1 and Christina Downey2, 1Loma Linda University, Loma Linda, CA, 2Loma Linda University Medical Center, Redlands, CA

    Background/Purpose: Osteoporosis (OSP) is common, carries high morbidity, significant cost and remains underrecognized and undertreated by health care providers (1). At a university-based academic health…
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