Abstracts tagged "Fatigue"

Abstract Number: 1763 • 2016 ACR/ARHP Annual Meeting
Long-Term Impact of Belimumab on Health-Related Quality of Life and Fatigue in Patients with Systemic Lupus Erythematosus Following 7 Years of Treatment Exposure: Impact of Clinical Characteristics over Time
Vibeke Strand¹, Pam Berry², Xiwu Lin², Yumi Asukai³, James Fettiplace³ and Sulabha Ramachandran², ¹Stanford University School of Medicine, Palo Alto, CA, ²GSK, Philadelphia, PA, ³GSK, Uxbridge, Middlesex, United Kingdom
Background/Purpose: Despite improvements in medical care leading to improved survival, systemic lupus erythematosus (SLE) adversely affects patients’ health related quality of life (HRQoL). To explore…
Abstract Number: 1768 • 2016 ACR/ARHP Annual Meeting
Fatigue in SLE Is Associated with Neuropsychiatric Involvement, Pain, Impaired Sleep and a Reduced Quality of Life
Andreas Jönsen¹, Pia C Sundgren², Jessika Nystedt³, Petra Nilsson³, Åsa Lilja⁴ and Anders A. Bengtsson¹, ¹Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden, ²Department of Diagnostic Radiology, Lund University, Lund, Sweden, ³Department of Clinical Sciences, Neurology, Lund University, Lund, Sweden, ⁴Center for Primary Health Care Research, Lund University, Malmö, Sweden
Background/Purpose: Fatigue is a major patient complaint in SLE, often severely impacting quality of life and activities including work. In this study, we analyze neuropsychiatric…
Abstract Number: 2226 • 2016 ACR/ARHP Annual Meeting
Independent and Combined Association of Overall Physical Fitness and Subjective Well-Being Components with Fatigue in Fibromyalgia
Fernando Estévez-López^1,2, Alberto Soriano-Maldonado¹, Inmaculada C Álvarez-Gallardo¹, Víctor Segura-Jiménez^1,3, Maria Rodriguez-Ayllon¹, Manuel Herrador-Colmenero¹, Manuel Pulido-Martos⁴, Rinie Geenen², Ana Carbonell-Baeza³ and Manuel Delgado-Fernández¹, ¹University of Granada, Granada, Spain, ²Utrecht University, Utrecht, Netherlands, ³University of Cádiz, Cádiz, Spain, ⁴University of Jaén, Jaén, Spain
Background/Purpose: The highest prevalence of severe fatigue in rheumatic diseases is observed in FM1. Physical fitness and subjective well-being have been suggested as resilience resources…
Abstract Number: 2370 • 2016 ACR/ARHP Annual Meeting
Factors Affecting Interval Changes in Perceived Fatigue over Five Years in Patients with Rheumatoid Arthritis Compared with Osteoarthritis
Simon Stebbings^1,2, Gareth Treharne³, J. Haxby Abbott⁴ and Andrew Gray⁵, ¹Dunedin Hospital, Department of Rheumatology, Dunedin, New Zealand, ²Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand, ³Psychology, University of Otago, Dunedin, New Zealand, ⁴Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, University of Otago, Dunedin, New Zealand, ⁵Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
Background/Purpose: In a previous cross-sectional study we noted higher fatigue levels in patients with advanced lower limb OA compared with RA, and identified differences in…
Abstract Number: 2922 • 2016 ACR/ARHP Annual Meeting
Disability, Fatigue, and Their Associates in Early Diffuse Cutaneous Systemic Sclerosis
Ariane L. Herrick¹, Sébastien Peytrignet², Xiaoyan Pan³, Roger Hesselstrand⁴, Luc Mouthon⁵, László Czirják⁶, Madelon C. Vonk⁷, Oliver Distler⁸, Joerg H.W Distler⁹, Edith Brown³, Kim Fligelstone³, Rachel Ochiel¹⁰, William Gregory¹¹, Alan Silman¹², Mark Lunt¹³ and Christopher Denton¹⁴, ¹Centre for Musculoskeletal Research, University of Manchester, MAHSC, Salford Royal Hospital, Manchester, United Kingdom, ²Manchester Academic Health Sciences Centre, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, ³Manchester Academic Health Science Centre, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, The University of Manchester, Manchester, United Kingdom, ⁴Department of Rheumatology, Lund University, Lund, Sweden, ⁵Internal Medicine, Hopital Cochin, Paris, France, ⁶Department of Rheumatology and Immunology, University of Pécs, Faculty of Medicine, Pécs, Hungary, ⁷Department of the Rheumatic Diseases, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands, ⁸Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁹Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich-Alexander University Erlangen-Nuremberg, Erlangen, Germany, ¹⁰Royal Free London NHS Foundation Trust, London, United Kingdom, ¹¹Rehabilitation Services, Salford Royal NHS Foundation Trust, Salford, United Kingdom, ¹²Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ¹³Arthritis Research UK Epidemiology Unit, The University of Manchester, Manchester Academic Health Sciences Centre, Manchester, United Kingdom, ¹⁴Centre for Rheumatology, Royal Free Hospital, London, Great Britain
Background/Purpose: ESOS (European Scleroderma Observational Study) was a prospective observational study of 326 patients with early diffuse cutaneous systemic sclerosis (dcSSc) from 50 centres. Here…
Abstract Number: 3235 • 2016 ACR/ARHP Annual Meeting
Long-Term Impact of Belimumab on Health-Related Quality of Life and Fatigue in Patients with Systemic Lupus Erythematosus: Up to 7 Years of Treatment Exposure
Vibeke Strand¹, Pam Berry², Sulabha Ramachandran² and James Fettiplace³, ¹Stanford University School of Medicine, Palo Alto, CA, ²GSK, Philadelphia, PA, ³GSK, Uxbridge, Middlesex, United Kingdom
Background/Purpose: Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that causes long-term organ damage over time and impairment in health-related quality of life (HRQoL).…
Abstract Number: 531 • 2016 ACR/ARHP Annual Meeting
Disease Activity and Physical Fatigue As Related to Adherence and Health Literacy in Patients with Rheumatoid Arthritis
Jens Gert Kuipers¹, Michael Koller², Florian Zeman², Karolina Mueller³ and Ulrich Rueffer⁴, ¹Department of Rheumatology, Red Cross Hospital Bremen, Bremen, Germany, ²Center of Clinical Studies, University Hospital Regensburg, Regensburg, Germany, ³Center for Clinical Studies, University Hospital Regensburg, Regensburg, Germany, ⁴German Fatigue Society, Cologne, Germany
Disease activity and physical fatigue as related to adherence and health literacy in patients with rheumatoid arthritis J. G. Kuipers1, M. Koller2, F. Zeman2, K.…
Abstract Number: 3243 • 2015 ACR/ARHP Annual Meeting
A Randomized Controlled Trial for a Physical Activity Intervention for RA Fatigue
Patricia P. Katz¹, Mary Margaretten², Steven Gregorich¹, Sandi Kaplan³, Stephanie Rush⁴ and Laura Trupin¹, ¹Medicine, University of California San Francisco, San Francisco, CA, ²Medicine, University of California, San Francisco, San Francisco, CA, ³Arthritis Research Group, University of California, San Francisco, CA, ⁴University of California, San Francisco, San Francisco, CA
Background/Purpose: Fatigue is a major problem for people with RA. Physical inactivity is an indirect risk factor for fatigue1. We tested the effect of a…
Abstract Number: 2883 • 2015 ACR/ARHP Annual Meeting
Relationship Between Improvements in Fatigue and Signs & Symptoms of Active Psoriatic: Arthritis a Sub-Analysis of a Phase 3 Study with Secukinumab
Laure Gossec¹, Tore K. Kvien², Philip G. Conaghan³, Mikkel Østergaard⁴, Juan D. Cañete⁵, C. Gaillez⁶, Shephard Mpofu⁶, Bintu Sherif⁷ and Steffen Jugl⁸, ¹Rheumatology Department, Paris 06 University,Hôpital Pitié Salpêtrière, Paris, France, ²Dept of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ⁴Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark, ⁵Rheumatology, Hospital Clinic and IDIBAPS, Barcelona, Spain, ⁶Novartis Pharma AG, Basel, Switzerland, ⁷RTI Health Solutions, Durham, NC, ⁸BF I&D GPA, Health Economics and Outcomes Research, Novartis Pharma AG, Basel, Switzerland
Background/Purpose: Fatigue is highly important to patients (pts) with psoriatic arthritis (PsA). Secukinumab, an anti-interleukin-17A monoclonal antibody, significantly improved the signs and symptoms of active…
Abstract Number: 2681 • 2015 ACR/ARHP Annual Meeting
Physical Function, Sleep, Depression but Not CRP Level Is Associated with Fatigue in Patients with Established Rheumatoid Arthritis
Yong Gil Hwang¹, Juan (June) Feng², Heather Eng², Jason Lyons², Anthony Fabio³ and Larry W. Moreland⁴, ¹Department of Medicine, University of Pittsburgh, Pittsburgh, PA, ²Epidemiology Data Center, University of Pittsburgh, Graduate School of Public Health, Pittsburgh, PA, ³Department Of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA, ⁴Rheumatology & Clinical Immunology, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Rheumatoid arthritis (RA) is characterized by inflammation of the joints and fatigue. Although many studies have identified risk factors for RA-associated fatigue, few studies…
Abstract Number: 2638 • 2015 ACR/ARHP Annual Meeting
Multiple Psychosocial Factors Influence Subjective Assessments of Disease Activity in Rheumatoid Arthritis
Ying L. Liu¹, Joan M. Bathon^2,3 and Jon T. Giles⁴, ¹Internal Medicine, Columbia University Medical Center, New York, NY, ²Medicine, Columbia University, College, New York, NY, ³Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY, ⁴Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY
Background/Purpose: Measuring disease activity in rheumatoid arthritis (RA) is important in evaluating efficacy of treatments, but many tests are subjective and lead to discordance in…
Abstract Number: 2637 • 2015 ACR/ARHP Annual Meeting
Prevalence of Unacceptable Pain and the Risk of Fatigue and Sleeping Problems in Early Rheumatoid Arthritis Patients
Joakim Lindqvist¹, Maria Sandberg^2,3, Saedis Saevarsdottir⁴, Reem Altawil⁴, Lars Klareskog⁵, Lars Alfredsson⁶ and Jon Lampa⁷, ¹Rheumatology Unit, Department of Medicine, Karolinska Institute, Stockholm, Sweden, ²Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden, ³The Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ⁴Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, ⁵Rheumatology Unit, Karolinska University Hospital, Stockholm, Sweden, ⁶Unit of Cardiovascular Epidemiology, Institute of Enviornmental Medicine, Karolinska Institutet, Karolinska Institutet, Stockholm, Sweden, ⁷Dep of Medicine, Rheumatology unit, Karolinska Institute, Karolinska Institute, Stockholm, Sweden
Background/Purpose: Pain is a commonly reported cause of affliction in RA-patients, also after adequate anti-rheumatic treatment. The objective of this study was to investigate the…
Abstract Number: 2337 • 2015 ACR/ARHP Annual Meeting
Depression, Bad Sleep Quality, and Functional Deficit Are Independently Associated with Persistent Fatigue in Arthritic Patients with Low Disease Activity Under Biological Dmards
Vitalie Nizeica¹, Myriam Normand², Delphine Denarie¹, Béatrice Pallot Prades¹, Philippe Collet¹, Adamah Amouzougan¹, Hervé Locrelle^1,2, Thierry Thomas^1,2 and Hubert Marotte^1,2, ¹Rheumatology Department, University Hospital of Saint-Etienne, Saint-Etienne, France, ²INSERM U1059/LBTO, Université de Lyon - Université Jean Monnet, Saint-Etienne, France
Background/Purpose: In rheumatoid arthritis (RA) or axial spondyloarthritis (axSpA) patients, fatigue has been mainly related to disease activity. Current management of rheumatic inflammatory diseases aims…
Abstract Number: 2335 • 2015 ACR/ARHP Annual Meeting
How Much Does Fatigue Contribute to the Physician and Patient Global Estimates in Different Rheumatic Diseases? Analysis from Routine Care on a Multidimensional Health Assessment Questionnaire (MDHAQ)
Isabel Castrejón¹, Elena Nikiphorou², Ruchi Jain¹, Annie Huang¹, Joel A. Block³ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Rheumatology, Addenbrooke's Hospital, Cambridge, United Kingdom, ³Rush University Medical Center, Chicago, IL
Background/Purpose: Fatigue is an important problem for many patients with rheumatic diseases. Fatigue is associated with disease severity, psychological distress, and a poorer quality of…
Abstract Number: 2281 • 2015 ACR/ARHP Annual Meeting
The Prediction of Fatigue in Early Rheumatoid Arthritis Patients
Margot Walter¹, T. Martijn Kuijper², Mieke Hazes^2,3, A.E.a.M. Weel⁴ and J.J. Luime⁵, ¹Rheumatology, Erasmus Medical Center, Rotterdam, Netherlands, ²Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ³Department of Rheumatology, Erasmus MC, University Medical Center, Rotterdam, Netherlands, ⁴Department of Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ⁵Department of Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands
The prediction of fatigue in early Rheumatoid arthritis patientsBackground/Purpose: Rheumatoid arthritis-related fatigue is a common problem with a high impact on patients. How fatigue develops…