Abstracts tagged "Fatigue"

Abstract Number: 2475 • 2018 ACR/ARHP Annual Meeting
Promis Pain Interference 6b and Fatigue 7a Short Forms and Profile-29 in Rheumatoid Arthritis Patients Treated with TNF Inhibitors
Clifton O. Bingham III¹, Sergio Schwartzman², Shelly Kafka³, Dennis Parenti³, Shawn Black³, Stephen Xu⁴, Wayne Langholff⁴ and Jeffrey R. Curtis⁵, ¹Johns Hopkins University, Baltimore, PA, ²Weill Cornell Medical College, New York, NY, ³Janssen Scientific Affairs, LLC, Horsham, PA, ⁴Janssen Research & Development, LLC, Spring House, PA, ⁵University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: PROMIS (Patient Reported Outcomes Measurement Information System) has been used in rheumatoid arthritis (RA) patients (Pts) to assess disease activity across multiple domains (i.e.…
Abstract Number: 2552 • 2018 ACR/ARHP Annual Meeting
Fatigue in Psoriatic Arthritis Patients Treated with Intravenous Golimumab: Early Improvement Is Associated with Week 24 Outcomes in Acr 20, 50, and Health-Related Quality of Life
Arthur Kavanaugh¹, M. Elaine Husni², Eric K. H. Chan³, Diane D. Harrison⁴, Lilianne Kim⁴, Kim Hung Lo⁴, Elizabeth C Hsia⁵ and Chenglong Han⁶, ¹University of California, San Diego, School of Medicine, La Jolla, CA, ²Orthopedic and Rheumatologic Institute, Cleveland Clinic, Cleveland, OH, ³Janssen Global Services, LLC, Raritan, NJ, ⁴Janssen Research & Development, LLC, Spring House, PA, ⁵Janssen Research & Development, LLC/University of Pennsylvania, Spring House/Philadelphia, PA, ⁶Janssen Global Services, LLC, Malvern, PA
Background/Purpose: To investigate improvement in fatigue in adult patients with active psoriatic arthritis (PsA) treated with intravenously administered (IV) golimumab, an anti-TNFα…
Abstract Number: 2561 • 2018 ACR/ARHP Annual Meeting
Rapid and Sustained Improvements in Patient-Reported Signs and Symptoms with Ixekizumab in Biologic-Naive and TNF-Inadequate Responder Patients with Psoriatic Arthritis
Ana-Maria Orbai¹, Dafna D Gladman², Julie Birt³, Amanda M. Gellett³, Chen-Yen Lin³ and Tore Kvien⁴, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²University of Toronto, Toronto, ON, Canada, ³Eli Lilly and Company, Indianapolis, IN, ⁴Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Ixekizumab (IXE), a high-affinity mAb that selectively targets IL-17A, has shown improvements up to Week (Wk) 24 across several domains of PsA (including ACR20)…
Abstract Number: 2652 • 2018 ACR/ARHP Annual Meeting
Engaging the Cholinergic Anti-Inflammatory Pathway By Stimulating the Vagus Nerve Reduces Pain and Fatigue in Patients with SLE
Cynthia Aranow¹, Martin Lesser², Meggan Mackay¹, Erik Anderson³, Theodoros P. Zanos², Timir Datta-Chaudhuri², Chad Bouton², Kevin J. Tracey⁴ and Betty Diamond¹, ¹The Feinstein Institute for Medical Research, Manhasset, NY, ²Feinstein Institute for Medical Research, Manhasset, NY, ³Autoimmune and Musculoskeletal Disease, The Feinstein Institute for Medical Research, Manhasset, NY, ⁴Laboratory of Biomedical Science, Feinstein Institute for Medical Research, Manhasset, NY
Background/Purpose: Musculoskeletal (MS) pain is a common symptom of patients with Systemic Lupus Erythematosus (SLE) affecting up to 95% of patients and contributing to…
Abstract Number: 1387 • 2018 ACR/ARHP Annual Meeting
Fatigue in Patients with Rheumatoid Arthritis As Compared to Different Groups of Cancer Patients
Jens Gert Kuipers¹, Michael Koller², Ulrich Rueffer³, Florian Zeman², Karolina Mueller⁴ and Joachim Weis⁵, ¹Clinic for Internal Rheumatology, Red Cross Hospital Bremen, Bremen, Germany, ²Center of Clinical Studies, University Hospital Regensburg, Regensburg, Germany, ³German Fatigue Society, Cologne, Germany, ⁴Center for Clinical Studies, University Hospital Regensburg, Regensburg, Germany, ⁵University Clinic Centre Freiburg, Freiburg, Germany
Background/Purpose: Fatigue is a common symptom in patients with rheumatoid arthritis (RA) as well as patients with cancer. Fatigue considerably reduces the quality of life…
Abstract Number: 1393 • 2018 ACR/ARHP Annual Meeting
Fatigue in Men and Women with Psoriatic Arthritis: An International Qualitative Study
Ana-Maria Orbai¹, Suzanne Grieb², Lilian van Tuyl³, Penelope Palominos⁴, Ying Ying Leung⁵, Karen Schipper⁶, Willemina Campbell⁷, Jessica Walsh⁸, Katherine Clegg Smith⁹, Laure Gossec¹⁰, Tania Gudu¹¹, Premarani Sinnathurai¹², Lyn March¹³, Soumya M. Reddy¹⁴, Xin Xiao Hui¹⁵, Clifton O. Bingham III¹⁶, Ricardo M. Xavier¹⁷ and Maarten de Wit¹⁸, ¹Johns Hopkins University School of Medicine, Baltimore, MD, ²Johns Hopkins Bayview Medical Center, Center for Child and Community Health Research, Baltimore, MD, ³Amsterdam Rheumatology and immunology Center | VU University Medical Center, Amsterdam, Netherlands, ⁴Rheumatology, Hospital de Clinicas de Porto Alegre, Santa Cecilia, Brazil, ⁵North District Hospital, Hong Kong, China, ⁶VU University, Amsterdam, Netherlands, ⁷Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, ⁸University of Utah School of Medicine, Salt Lake City, UT, USA, Salt Lake City, UT, ⁹Health, Behavior and Society, Johns Hopkins University Bloomberg School of Public Health, Batimore, MD, ¹⁰Sorbonne Universités, Paris, France, ¹¹University of Medicine Carol Davila Bucuresti, Romania, Bucuresti, Romania, ¹²Rheumatology, University of Sydney, Sydney, Australia, ¹³Department of Rheumatology, Northern Clinical School, Institute of Bone and Joint Research, Kolling Institute, University of Sydney & Department of Rheumatology, Royal North Shore Hospital, St Leonards, Sydney, Australia, ¹⁴Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ¹⁵Rheumatology, Singapore General Hospital, Singapore, Singapore, ¹⁶Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ¹⁷Universidade Federal do Rio Grande do Sul Porto Alegre, Rio Grande do Sul, Brazil, ¹⁸EULAR standing committee of PARE, Zurich, Switzerland
Background/Purpose: Fatigue is prevalent and important to people with psoriatic arthritis (PsA)1. Women with PsA have worse symptom and life impact scores than men, including…
Abstract Number: 1402 • 2018 ACR/ARHP Annual Meeting
The Relationship of Pain, Fatigue and Emotional Distress with Quality of Life in Juvenile Myositis
Kyle J. Fahey¹, Elizabeth L. Gray², Rowland W. Chang³, David Cella⁴, Lauren M. Pachman⁵ and Kaveh Ardalan⁶, ¹Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Preventive Medicine, Medicine, and Physical Medicine & Rehabilitation, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Departments of Medical Social Sciences, Neurology, Pediatrics, Preventive Medicine, and Psychiatry and Behavioral Sciences,, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁵Cure JM Program of Excellence in Juvenile Myositis Research, Stanley Manne Children’s Research Institute, affiliated with Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, ⁶Departments of Pediatrics and Medical Social Sciences, Division of Rheumatology, Northwestern University Feinberg School of Medicine/Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL
Background/Purpose: Juvenile Myositis (JM) is an autoimmune disease that negatively impacts quality of life (QoL) outcomes via muscle weakness and vasculopathic rashes. The relative contribution…
Abstract Number: 1918 • 2018 ACR/ARHP Annual Meeting
Defining Pain That Does Not Interfere with Activities Among Rheumatoid Arthritis (RA) Patients
Yvonne C. Lee¹, Patricia Katz^2,3, Amanda Quebe⁴, Luna Sun⁴, Himanshu Patel⁴, Carol L. Gaich⁴, Natalie Boytsov⁴ and Kaleb Michaud^5,6, ¹Northwestern University Feinberg School of Medicine, Chicago, IL, ²Forward/National Data Bank for Rheumatic Diseases, Wichita, KS, ³University of California San Francisco, San Francisco, CA, ⁴Eli Lilly and Company, Indianapolis, IN, ⁵Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁶FORWARD, The National Databank for Rheumatic Diseases, Wichita, KS
Background/Purpose: RA patients differ in the degree to which pain interferes with function. To improve function, an understanding of this diversity is needed. Our objectives…
Abstract Number: 2376 • 2018 ACR/ARHP Annual Meeting
Something for Us: Client Perspectives on Lupus Self-Management Programming Using the 5-a Behavior Change Model
Brenda L Frie, Occupational Therapy Dept., St. Catherine University, St. Paul, MN
Background/Purpose: Systemic lupus erythematosus is the most common and most severe form of lupus involving multiple body systems including the blood, muscles, joints, organs and…
Abstract Number: 1354 • 2017 ACR/ARHP Annual Meeting
Fatigue, Poor Health and Mood Disturbance Persist in Rheumatoid Arthritis and Psoriatic Arthritis Patients Despite Disease Remission: The OPAL Deeper Study
Paul Bird¹, Hedley Griffiths², Geoff Littlejohn³, Peter Youssef⁴, Fred Joshua⁵, Peter Nash⁶, Julien De Jager⁷, Tegan Smith⁸, Janet Sanburg⁹ and Kathleen Tymms¹⁰, ¹University of New South Wales, Sydney, Australia, ²Barwon Rheumatology Service, Geelong, Australia, ³Medicine, Monash, Melbourne, Australia, ⁴Royal Prince Alfred Hospital, Camperdown, Sydney, Australia, ⁵Combined Rheumatology Practice, Sydney, NSW, Australia, ⁶University of Queensland, Brisbane, Australia, ⁷University Of Queensland, Southport, Australia, ⁸OPAL, Sydney, Australia, ⁹OPAL, Melbourne, Australia, ¹⁰ANU, Canberra, Australia
Background/Purpose: Patient reported outcomes are recognized as increasingly important in defining the full burden of disease experienced by patients with rheumatic disease. Traditional measures of…
Abstract Number: 1388 • 2017 ACR/ARHP Annual Meeting
Fatigue Is Strongly Associated with the Patient Global Assessment and May Affect Disease Severity and Clinical Remission in Patients with Rheumatoid Arthritis: A Cross-Sectional Study from IORRA, a Large Observational Cohort of Japanese Rheumatoid Arthritis Patients
Naoki Sugimoto¹, Eiichi Tanaka¹, Eisuke Inoue^1,2, Kumiko Saka¹, Eri Sugano¹, Naohiro Sugitani¹, Moeko Ochiai¹, Yoko Shimizu¹, Rei Yamaguchi¹, Katsunori Ikari¹, Ayako Nakajima¹, Atsuo Taniguchi¹ and Hisashi Yamanaka¹, ¹Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ²Division of Medical Informatics, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Fatigue is a common complaint in patients with rheumatoid arthritis (RA)1. However, its impact on disease activity and clinical remission in patients with RA…
Abstract Number: 1500 • 2017 ACR/ARHP Annual Meeting
Longitudinal Analysis of Different Therapeutic Strategies in Patients with Primary Sjögren’s Syndrome
Kristen Davies¹, Kamran Mirza¹, Jessica Tarn², Marian Regan³, Saravanan Vadivelu⁴, Gavin Clunie⁵, Jacqueline Andrews⁶, Elizabeth Price⁷, Steve Young-Min⁸, Ian Giles⁹, Bhaskar Dasgupta¹⁰, Cathy Lawson¹¹, Nagui Gendi¹², Neil J. McHugh¹³, Michele Bombardieri¹⁴, Costantino Pitzalis¹⁴, Nurhan Sutcliffe¹⁴, Simon Bowman¹⁵, Dennis Lendrem^16,17 and Wan-Fai Ng^2,18, ¹Institute of Cellular Medicine, Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom, ²Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom, ³Royal Derby Hospital, Derby, UK, Derby, United Kingdom, ⁴Queen Elizabeth Hospital, Gateshead, UK, Gateshead, United Kingdom, ⁵Ipswich Hospital NHS Trust, Ipswich, UK, Ipswich, United Kingdom, ⁶Leeds Teaching Hospitals NHS Trust, Leeds, UK, Leeds, United Kingdom, ⁷Great Western Hospital, Swindon, UK, Swindon, United Kingdom, ⁸Queen Alexander Hospital, Portsmouth, UK, Portsmouth, United Kingdom, ⁹Centre for Rheumatology, University College London, Centre for Rheumatology, University College London, UK, London, United Kingdom, ¹⁰Rheumatology, Southend University Hospital NHS Foundation Trust, Southend, UK, Westcliff-on-Sea, United Kingdom, ¹¹Harrogate District Hospital, Harrogate, UK, Harrogate, United Kingdom, ¹²Basildon and Thurrock University Hospital, Basildon, UK, Basildon, United Kingdom, ¹³Royal National Hospital for Rheumatic Diseases, Bath, UK, Bath, United Kingdom, ¹⁴Barts Health NHS Trust & Barts and the London School of Medicine & Dentistry, London, UK, London, United Kingdom, ¹⁵Department of Rheumatology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK, Birmingham, United Kingdom, ¹⁶Musculoskeletal Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle-Upon-Tyne, UK, Newcastle-upon-Tyne, United Kingdom, ¹⁷Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK, Newcastle, United Kingdom, ¹⁸Newcastle-upon-Tyne Hospitals NHS Foundation Trust, Newcastle-upon-Tyne, UK, Newcastle-Upon-Tyne, United Kingdom
Background/Purpose: Primary Sjögren’s syndrome (pSS) is a systemic autoimmune rheumatic disease characterised by sicca features and systemic manifestations such as pain and fatigue. The classic…
Abstract Number: 1528 • 2017 ACR/ARHP Annual Meeting
Secukinumab Provides Rapid and Sustained Pain Relief in Ankylosing Spondylitis Patients with Normal or Elevated Baseline CRP Levels and Correlated with Improvement in Fatigue
Atul A. Deodhar¹, Philip G. Conaghan², Tore K Kvien³, Vibeke Strand⁴, Lawrence Rasouliyan⁵, Brian Porter⁶, Steffen Jugl⁷ and Kunal Gandhi⁶, ¹Oregon Health & Science University, Portland, OR, ²University of Leeds, Leeds, United Kingdom, ³Diakonhjemmet Hospital, Oslo, Norway, ⁴Stanford University School of Medicine, Palo Alto, CA, ⁵RTI Health Solutions, Barcelona, Spain, ⁶Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁷Novartis Pharma AG, Basel, Switzerland
Background/Purpose: Secukinumab has demonstrated sustained efficacy in patients (pts) with active AS.1,2 We investigated improvement in pain and fatigue scores from baseline (BL) through Week…
Abstract Number: 1602 • 2017 ACR/ARHP Annual Meeting
Fatigue in Systemic Lupus: The Role of Disease Activity and Its Mediators
Desiree R Azizoddin¹, Meenakshi Jolly², Joel A. Block³ and Perry M. Nicassio⁴, ¹Department of Medicine and Behavioral Sciences, Rush University, Chicago, IL, ²Rush, Chicago, IL, ³Division of Rheumatology, Rush University Medical Center, Chicago, IL, ⁴Cousins Center for PNI, UCLA, LA, CA
Background/Purpose: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease that leads to a variety of negative health outcomes. Though treatment continues to advance, fatigue…
Abstract Number: 2254 • 2017 ACR/ARHP Annual Meeting
Disability (HAQ) and Quality of Life (SF-12) As Related to Adherence and Health Literacyin Patients with Rheumatoid Arthritis – the Trace-Study
Jens Gert Kuipers¹, Michael Koller², Florian Zeman², Karolina Mueller² and Jens Ulrich Rueffer³, ¹Department of Rheumatology, Red Cross Hospital Bremen, Bremen, Germany, ²University Hospital Regensburg, Center for Clinical Studies, Regensburg, Germany, ³German Fatigue Society, Cologne, Germany
Background/Purpose: Disabilities in daily living and quality of life are key endpoints to evaluate the outcome of treatment for rheumatoid arthritis (RA). Among factors that…