ACR Meeting Abstracts

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Abstracts tagged "Fatigue"

  • Abstract Number: 2408 • ACR Convergence 2024

    Impact of Pain and Fatigue on Quality of Life Among Patients with Systemic Lupus Erythematosus

    Amanda Eudy1, Megan Clowse2, Meenakshi Jolly3, David Pisetsky4, Kai Sun5, Rebecca Sadun5, Lisa Criscione-Schreiber6, Mithu Maheswaranathan6, Jayanth Doss5 and Jennifer Rogers6, 1Duke University, Raleigh, NC, 2Duke University, Chapel Hill, NC, 3Rush University Medical Center, Chicago, 4Duke University Medical Center, Durham, NC, 5Duke University, Durham, NC, 6Duke University, Durham

    Background/Purpose: Our prior qualitative work discovered a subgroup of patients with SLE who experience persistent symptoms of fatigue and widespread pain, even on self-described “good…
  • Abstract Number: 0362 • ACR Convergence 2024

    Development of a Theory-based Digital Messaging Program to Reduce Fatigue in Systemic Lupus Erythematosus

    Anna Deck1, Paula Caras2, Kiran Singh3, Monique Gore-Massy4, Faye Chiu5, Sara Folta6 and Shanthini Kasturi3, 1Tufts University School of Medicine, Portland, ME, 2Tufts University School of Medicine, Boston, MA, 3Tufts Medical Center, Boston, MA, 4Lupus Foundation of America, New Jersey, 5N/A, New York City, NY, 6Tufts University/Tufts University Friedman School of Nutrition, Boston, MA

    Background/Purpose: Fatigue is the single most prevalent symptom of systemic lupus erythematous (SLE), affecting 80-90% of patients, and is often refractory to pharmacologic therapy. Non-pharmacologic…
  • Abstract Number: 2654 • ACR Convergence 2024

    Adapting and Testing a Cognitive Rehabilitation Intervention Tailored for People with Systemic Sclerosis: Acceptability, Feasibility, & Impact on Health-related Outcomes

    Yen Chen1, Mary Alore2, Dinesh Khanna1 and Susan Murphy3, 1University of Michigan, Ann Arbor, MI, 2Self-employed, TROY, MI, 3University of Michigan, Plymouth, MI

    Background/Purpose: Cognitive dysfunction affects up to 87% of individuals with systemic sclerosis (SSc), often significantly impairing their work and daily activities and exacerbating other symptoms…
  • Abstract Number: 0518 • ACR Convergence 2024

    Sustained Patient Meaningful Outcomes of Pain and Fatigue Relief and Improved Physical Functioning with Filgotinib in Rheumatoid Arthritis: A Post Hoc Analysis

    Rieke Alten1, Bruno Fautrel2, Philip G Conaghan3, Dick de Vries4, Margaux Faes5, Mercedes Piovesan6, Katrien Van Beneden7, Chris Watson8, Angelique E.A.M. Weel-Koenders9, Eugen Feist10 and Kurt de Vlam11, 1Department of Internal Medicine and Rheumatology, Schlosspark Klinik, University Medicine Berlin, Berlin, Germany, 2INSERM, UMRS 1136, Institut Pierre Louis d'Epidémiologie et de Santé Publique, and Sorbonne University – Assistance Publique-Hôpitaux de Paris, Département de Rhumatologie, Hôpital Pitié-Salpêtrière, Paris, Ile-de-France, France, 3Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, and NIHR Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 4Clinical Development, Galapagos BV, Leiden, Netherlands, 5Biostatistics, Galapagos NV, Mechelen, Belgium, 6Medical Affairs, Galapagos Biopharma Spain SLU, Madrid, Spain, 7Medical Affairs, Galapagos NV, Mechelen, Belgium, 8Medical Affairs, Galapagos Biotech Ltd, Cambridge, United Kingdom, 9Erasmus School of Health Policy and Management, Erasmus University Rotterdam, and Department of Rheumatology and Clinical Immunology, Maasstad Hospital, Rotterdam, Netherlands, 10Department of Rheumatology, Helios Clinic Vogelsang-Gommern, cooperation partner of the Otto von Guericke University Magdeburg, Gommern, Germany, 11Department of Rheumatology, UZ Leuven, and Department of Development and Regeneration, Skeletal Biology and Engineering Research Center, KU Leuven, Leuven, Belgium

    Background/Purpose: Quality of life for patients with RA can be severely impacted by pain, fatigue and impaired physical functioning.1 Filgotinib (FIL) has demonstrated early onset…
  • Abstract Number: 2657 • ACR Convergence 2024

    Prevalence of Anxiety, Depression, and Fatigue in Patients with Rheumatic Diseases: A Cross-Sectional Study of 1014 Cases

    Gabriela Anais Madrid-Lopez1, Maria Corral-Trujillo2, Amado Arturo Diaz-Guerrero3, Luisa Fernanda Mata-Torres3, Eva Galindo Calvillo4, Jesus Cardenas-de la Garza2, Ivan Hernandez Galarza5, Miguel Angel Villarreal-Alarcon6 and Dionicio Galarza-Delgado7, 1Facultad de Medicina, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 2Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico, 3Universidad Autónoma de Nuevo León, Monterrey, Mexico, 4Universidad Autónoma de Nuevo León, Saltillo, Coahuila, Mexico, 5University Hospital, UANL, San Pedro Garza Garcia, Nuevo León, Mexico, 6Division of Rheumatology, University Hospital "Dr. Jose Eleuterio Gonzalez", Universidad Autonoma de Nuevo Leon, Monterrey, Mexico, 7UANL Hospital Universitario, Monterrey, Nuevo León, Mexico

    Background/Purpose: Individuals diagnosed with rheumatic diseases (RD) have an elevated susceptibility to mental health disorders. A study conducted among patients with RD revealed a prevalence…
  • Abstract Number: 1654 • ACR Convergence 2023

    A Peer Health Coached Resilience-Based Energy Management Program Was Effective in Improving Fatigue and Other Outcomes in People with Systemic Sclerosis: Results of a Randomized Controlled Trial

    Susan Murphy1, Yen Chen2, Mary Alore2, Sheri Hicks2, Adam Pape2, Afton Hassett2, Anna Kratz2, Daniel Whibley2, Alexandra Harper3, Suiyuan Huang2, Gina Jay2, Shannen Bolde2 and Dinesh Khanna2, 1University of Michigan, Plymouth, MI, 2University of Michigan, Ann Arbor, MI, 3University of Michigan, Ypsilanti Charter Twp, MI

    Background/Purpose: Systemic sclerosis (SSc), a rare autoimmune condition, has a high chronic symptom burden that can have dramatic, life-altering effects on function and quality of…
  • Abstract Number: 1835 • ACR Convergence 2023

    A Survey on Fibromyalgia-Related Knowledge Among Internal Medicine Residents

    Summia Matin Afridi1, Ahmad Raja2 and Muhammad Daniyal3, 1Albany Medical Center, Albany, NY, 2Mary Imogene Bassett Hospital, Evanston, IL, 3Mary Imogene Bassett Hospital, Cooperstown, NY

    Background/Purpose: Fibromyalgia is a chronic pain syndrome that commonly presents with fatigue, widespread musculoskeletal pain, and sleep disturbances. Patients can also have accompanying somatic and…
  • Abstract Number: 0066 • ACR Convergence 2023

    Mitochondrial Dysfunction and Fatigue in Sjögren’s Disease

    Biji T Kurien1, Rebecca Wood2, Gavin Pharaoh3, Joshua Cavett1, Valerie Lewis1, Bhaskaran Shylesh1, Lida radfar1, Astrid Rasmussen1, Christopher Lessard1, A. Darise Farris1, Kathy Sivils4, Kristi Koelsch1, Holly Van Remmen1 and R Hal Scofield5, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2University of Oklahoma Health Sciences Center, Edmond, OK, 3University of Washington, Seattle, WA, 4Janssen Research & Development, LLC, Edmond, OK, 5Oklahoma City Veterans Affairs Medical Center, Oklahoma City, OK

    Background/Purpose: Sjögren's disease (SjD) is a chronic, autoimmune condition with diminished lacrimal and salivary gland secretion leading to keratoconjunctivitis sicca and xerostomia, respectively. In addition,…
  • Abstract Number: 1836 • ACR Convergence 2023

    Embracing a Biopsychosocial Approach to Fibromyalgia-like Symptoms in People with SLE: Insights from the Type 2 SLE Consortium

    Jennifer Rogers1, Megan Clowse2 and Amanda Eudy3, 1Duke University, Durham, NC, 2Duke University, Chapel Hill, NC, 3Duke University, Raleigh, NC

    Background/Purpose: Patients with SLE experience distressing fibromyalgia-like symptoms of fatigue, widespread pain, mood disturbance, and brain fog that negatively impact quality of life and are…
  • Abstract Number: 0527 • ACR Convergence 2023

    Bimekizumab Treatment Impact on Pain and Fatigue in Patients with Active Psoriatic Arthritis Who Were Biologic DMARD‑Naïve or Had Inadequate Response or Intolerance to TNF-α Inhibitors: 1-Year Results from Two Phase 3 Studies

    M. Elaine Husni1, Philip J. Mease2, Joseph Merola3, Frank Behrens4, Ennio G Favalli5, Dennis McGonagle6, William R Tillett7, Shigeyoshi Tsuji8, Barbara Ink9, Rajan Bajracharya9, Jérémy Lambert10, Jason Coarse11 and Laure Gossec12, 1Cleveland Clinic / Department of Rheumatic and Immunologic Diseases, Cleveland, OH, 2Swedish Medical Center/Providence St. Joseph Health and University of Washington School of Medicine, Seattle, WA, 3Harvard Medical School, Brigham and Women's Hospital, Newton, MA, 4Goethe University, Division of Rheumatology, University Hospital and Fraunhofer Institute for Translational Medicine & Pharmacology, Frankfurt, Germany, 5ASST Gaetano Pini-CTO, University of Milan, Department of Rheumatology, Milan, Italy, 6Leeds Biomedical Research Centre, University of Leeds, Leeds, United Kingdom, 7Department of Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 8Nippon Life Hospital, Osaka, Japan, 9UCB Pharma, Slough, United Kingdom, 10UCB Pharma, Irigny, France, 11UCB Pharma, Morrisville, NC, 12Sorbonne Université and Pitié Salpêtrière Hospital, Paris, France

    Background/Purpose: Pain and fatigue have been identified by patients (pts) as key features of PsA, driving the impact on their health-related quality of life.1 Bimekizumab…
  • Abstract Number: 1846 • ACR Convergence 2023

    A Longitudinal Study: The Benefits of Non-Pharmacological Approaches to Improve Self-Reported Pain, Stiffness, and Fatigue in Individuals with Musculoskeletal Disorders

    Titilayo Adeniran, Bertilia Trieu, Claudia Zurlini, Bonnie McGrath, Linda Roberts, Pamela Sanchez-Villagomez, Vilma Briones, Robyn Wiesel, Sandra Goldsmith and Laura Robbins, Hospital for Special Surgery, New York, NY

    Background/Purpose: Musculoskeletal disorders are a leading cause of disability worldwide, with low back pain being one of the primary causes. The World Health Organization (WHO)…
  • Abstract Number: 0629 • ACR Convergence 2023

    Negative Affect, Anxiety and Fatigue Moderate the Association Between Pain Intensity and Physical Function in People with Systemic Sclerosis

    Daniel Whibley1, Yen Chen1, Anna Kratz1, Dinesh Khanna1 and Susan Murphy2, 1University of Michigan, Ann Arbor, MI, 2University of Michigan, Plymouth, MI

    Background/Purpose: Pain is a common symptom of systemic sclerosis (SSc), affecting over 80% of those living with the condition, with over a third experiencing pain…
  • Abstract Number: 1861 • ACR Convergence 2023

    Efficacy of Non-pharmacological Interventions: A Systematic Review Informing the 2023 EULAR Recommendations for the Management of Fatigue in People with Inflammatory Rheumatic and Musculoskeletal Diseases

    Eduardo Santos1, Bayram Farisogullari2, Emma Dures3, Rinie Geenen4 and Pedro Machado5, 1Health Sciences Research Unit: Nursing (UICISA: E), Nursing School of Coimbra (ESEnfC), Coimbra, Portugal, 2Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, 3Academic Rheumatology, Bristol Royal Infirmary; and Faculty of Health and Applied Sciences, University of the West of England, Bristol, United Kingdom, 4Utrecht University, Vorstenbosch, Netherlands, 5Centre for Rheumatology & Department of Neuromuscular Diseases, University College London, London, UK. Department of Rheumatology, Northwick Park Hospital, London North West University Healthcare NHS trust, London, UK., London, United Kingdom

    Background/Purpose: To identify the best evidence on the efficacy of non-pharmacological interventions in reducing fatigue in people with I-RMDs and to summarise their safety in…
  • Abstract Number: 0721 • ACR Convergence 2023

    Characterization of Numeric Rating Scales for Symptom Assessment in Polymyalgia Rheumatica

    Tonya K Marmon1, Jason C Cole2, Claire Owen3, Sarah Mackie4 and David Katz5, 1Marmon Biostatistics, Seattle, WA, 2P3 Research Consulting, Torrance, CA, 3Austin Health, Malvern East, Australia, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; Leeds Biomedical Research Centre, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 5Sparrow Pharmaceuticals, Portland, OR

    Background/Purpose: Pain, stiffness, and fatigue have been defined as core assessment domains in polymyalgia rheumatica (PMR) by the OMERACT PMR Working Group (PMRWG). Patient partners…
  • Abstract Number: 1970 • ACR Convergence 2023

    Impaired Health-Related Quality of Life in Patients with Idiopathic Inflammatory Myopathies: A Cross-Sectional Analysis from the COVAD Dataset

    Akira Yoshida1, Yuan Li2, Vahed Maroufy2, Masataka Kuwana1, Naveen R3, Ashima Makol4, Parikshit Sen5, James Lilleker6, Vishwesh Agarwal7, Sinan Kardes8, Jessica Day9, Marcin Milchert10, Mrudula Joshi11, Tamer A Gheita12, Babur Salim13, Tsvetelina Velikova14, Abraham Edgar Gracia-Ramos15, Ioannis Parodis16, Elena Nikiphorou17, Ai Lyn Tan18, Arvind Nune19, Lorenzo Cavagna20, Miguel Angel Saavedra Salinas21, Samuel Shinjo22, Nelly Ziade23, Johannes Knitza24, Oliver Distler25, Hector Chinoy26, Vikas Agarwal3, Rohit Aggarwal27, Latika Gupta28 and COVAD Study Group29, 1Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 2University of Texas Health Science Center at Houston, Houston, TX, 3Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, 4Mayo Clinic, Rochester, MN, Rochester, MN, 5Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, 6Centre for Musculoskeletal Research, Division of Musculoskeletal and Dermatological Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK; Manchester Centre for Clinical Neurosciences, Salford Royal NHS Foundation Trust, Salford, UK. Orcid ID: 0000-0002-9230-4137., Manchester, United Kingdom, 7Mahatma Gandhi Missions Medical College, Lucknow, India, 8Istanbul University, Istanbul, Turkey, 9Walter and Eliza Hall Institute, Melbourne, Australia, 10Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, 11Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 12Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt, 13Fauji foundation hospital Rawalpindi, Rawalpindi, Pakistan, 14Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, Sofia, Bulgaria, 15Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico, 16Karolinska Institutet, Stockholm, Sweden, 17King's College London, London, United Kingdom, 18University of Leeds, Leeds, United Kingdom, 19Southport & Ormskirk NHS Foundation Trust, Liverpool, United Kingdom, 20Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 21IMSS, Mexico City, Mexico, 22Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, 23Saint-Joseph University, Beirut, Lebanon, 24Department of Internal Medicine 3 Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, 25Department of Rheumatology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, 26The University of Manchester, Sale, United Kingdom, 27University of Pittsburgh, Pittsburgh, PA, 28Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 29-, -

    Background/Purpose: The significance of Health-related quality of life (HRQoL) in patients with autoimmune diseases is well acknowledged. Unfortunately, there is dearth of data on the…
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