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Abstracts tagged "Disease Activity"

  • Abstract Number: 0584 • ACR Convergence 2025

    Difficult-to-Manage Axial Spondyloarthritis According to ASAS Criteria in Reuma-Check Cohort: Frequency, Predictive Factors, and Treatment Patterns.

    Rodrigo García Salinas1, Nataly Mejia2, Santiago Ruta3 and Sebastian Magri4, 1Hospital Italiano La Plata, La Plata, Argentina, 2Hospital Italiano de La Plata, La Plata, Argentina, 3Hospital San Martin de La Plata, La Plata, Argentina, 4Hospital Italiano La Plata, Melchor Romero, Argentina

    Background/Purpose: The concept of difficult-to-Manage axial spondyloarthritis (axSpA D2M), recently introduced by ASAS, describes patients who fail ≥2 lines of b-tsDMARDs treatment and remain active…
  • Abstract Number: 2409 • ACR Convergence 2025

    Cutaneous Lupus Activity Investigator’s Global Assessment―Revised (CLA-IGA-R) Content Validity: Cutaneous Lupus Erythematosus (CLE) Patient Qualitative Study

    Joseph F Merola1, Weihong Yang2, Qianyun Li2, Helen Doll3, Jason Randall3, Catherine Barbey4 and Feng Zeng2, 1Department of Dermatology and Department of Medicine, UT Southwestern Medical Center, Dallas, TX, 2Biogen, Cambridge, MA, 3Clinical Outcomes Solutions, Folkestone, Kent, United Kingdom, 4Biogen, Baar, Switzerland

    Background/Purpose: The Cutaneous Lupus Activity Investigator’s Global Assessment-Revised (CLA-IGA-R) is an emerging clinician-reported outcome measure for severity of Cutaneous Lupus Erythematosus (CLE) disease activity, developed…
  • Abstract Number: 2253 • ACR Convergence 2025

    Wrist-worn Wearable Device Data Can Be a New Digital Biomarker For Disease Activity In Rheumatoid Arthritis: a Multicenter Single-arm Prospective Study

    Misako Higashida-Konishi1, Keisuke Izumi2, Shuntaro Saito Saito3, Hiroki Tabata4, Satoshi Hama4, Tatsuhiro Oshige4, Yutaka Okano4, Hisaji Oshima4, Katsuya Suzuki4, Jiro Sakamoto5, Toshikazu Fukami5, Kazumichi Minato5, Nobuhiko Kajio6, Yasushi Kondo3, Hiroaki Taguchi6 and Yuko Kaneko3, 1NHO Tokyo Medical Center, Tokyo Meguroku, Japan, 2Division of Rheumatology, Department of Medicine, NHO Tokyo Medical Center/Keio University School of Medicine/TechDoctor, Inc., Tokyo, Japan, 3Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 4Division of Rheumatology, Department of Medicine, NHO Tokyo Medical Center, Tokyo, Japan, 5TechDoctor, Inc., Tokyo, Japan, 6Department of Rheumatology, Kawasaki Municipal Hospital, Kanagawa, Japan

    Background/Purpose: Previous studies have estimated physical and mental states using wearable device data such as from smartwatches [1–3]. This study aimed to identify digital biomarkers…
  • Abstract Number: 1675 • ACR Convergence 2025

    Neuroimmune modulation in patients with active rheumatoid arthritis with an inadequate response to TNF inhibitors (TNFi)

    Guillermo Valenzuela1, Jane Box2, Angela Crowley3, Joshua June4, Pendleton Wickersham5, Jeff Peterson6, Michael Thakor7, Susan Kim8, Tina Shah9, David Chernoff10 and John Tesser11, 1Integral Rheumatology & Immunology Specialists, Plantation, FL, 2DJL Clinical Research, PLLC, Charlotte, NC, 3Illinois Bone and Joint Institute - Hinsdale Orthopaedics, Hinsdale, IL, 4Great Lakes Center of Rheumatology, Lansing, MI, 5Arthritis Associates PA, San Antonio, TX, 6Western Washington Arthritis Clinic, Seattle, WA, 7arthritis and rheumatology, Fort Collins, CO, 8Lehigh Valley Hospital Network, Allentown, PA, 9Kansas City Physician Partners, Kansas City, MO, 10SetPoint Medical, Sausalito, CA, 11Arizona Arthritis & Rheumatology Associates, Phoenix, AZ

    Background/Purpose: A substantial number of patients with rheumatoid arthritis (RA) experience treatment failure, incomplete response, or intolerance to TNFis (TNFi-IR). Neuroimmune modulation using an implantable…
  • Abstract Number: 1433 • ACR Convergence 2025

    Identifying Predictors of Difficult-to-Manage Axial Spondyloarthritis: Real-World Insights from a Taiwanese Registry Cohort

    Yen-An Chang and Ming-Han Chen, Division of Allergy, Immunology & Rheumatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Taipei, Taiwan (Republic of China)

    Background/Purpose: The concept of Difficult-to-Manage Axial Spondyloarthritis (D2M-ax-SpA) was recently introduced by the Assessment of Spondyloarthritis International Society (ASAS). According to this new definition, D2M-ax-SpA…
  • Abstract Number: 1312 • ACR Convergence 2025

    Evolution of patients with active rheumatoid arthritis: analysis of disease activity trajectories in a tertiary‑care rheumatology department

    Elodie Portier1, Olivier Fogel2, Terkia Medkour3, Sophie Hecquet3 and Jérôme AVOUAC3, 1Rheumatology department, Bicetre hospital, Le Kremlin Bicetre, France, 2AP-HP, Paris, France, 3Rheumatology department, Cochin hospital, Paris, France

    Background/Purpose: The objective of this study was to identify clusters of patients with rheumatoid arthritis (RA) in clinical practice, according to evolution of disease activity…
  • Abstract Number: 0648 • ACR Convergence 2025

    Real World Comparative Use of Anifrolumab in Systemic Lupus Erythematosus and Cutaneous Lupus Erythematosus: A Multicenter Cohort Study

    Rajaie Namas1, Sarah Al Qassimi2, Rowaida Abdou3, Jawahir Alameri2, Reem Alblooshi4, Fatima Abdulla4, Muriel Ghosn4, Amir Malik4, Raghda Almaashari4, Fulvio Salvo4, Mohamed Abuzakouk4, Atheer Al Ansari5, Hazem Helmy Ali Rifaai5, Ahlam Almarzooqi6, Asia Mubashir7, Ahmed Aldhaheri4, Suzan Attar8 and Mohamed Elarabi9, 1Cleveland Clinic Abu Dhabi, Detroit, MI, 2Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, 3NMC Specialty Hospital Abu Dhabi, Abu Dhabi, United Arab Emirates, 4Cleveland Clinic Abu Dhabi, Abu Dhabi, 5Mediclinic, Abu Dhabi, United Arab Emirates, 6Emirates Health Services, Sharjah, United Arab Emirates, 7Cleveland Clinic, Abu Dhabi, Abu Dhabi, United Arab Emirates, 8King Abdulaziz University, Saudi Arabia, Jeddah, Saudi Arabia, 9Cleveland Clinic Abu Dhabi, Hannon, ON, Canada

    Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiorgan organ damage, and early mortality. Anifrolumab (ANI), a human monoclonal antibody targeting the…
  • Abstract Number: 0495 • ACR Convergence 2025

    Effectiveness and Safety of Iguratimod with Background Methotrexate Therapy in Indian Patients with Rheumatoid Arthritis: A Randomized Double Blinded Placebo Controlled Study

    MIDHUN SAKRAVARTHY JALANATHAN1, Mehdi Ali Mirza1, Vijaya prasanna Parimi2, Seethalakshmi S1 and Tejaswini Ramineni3, 1ESIC Medical College and Hospital, Sanathanagar, Hyderabad, Telangana, India, 2ESIC Medical College and Super Specilaity Hospital, hyderabad, Telangana, India, 3Esic Medical College And Hospital, Sanathnagar, Hyderabad, Telangana, India

    Background/Purpose: Iguratimod (IGU), an oral synthetic disease-modifying antirheumatic drug (DMARD), has shown significant efficacy and safety in rheumatoid arthritis (RA) when combined with methotrexate (MTX)…
  • Abstract Number: 0409 • ACR Convergence 2025

    Discordance Between Disease Activity and Patient-Reported Outcomes in Patients with Juvenile Idiopathic Arthritis

    Julia Harris1, Leslie Favier2, Emily Fox3, Jordan Jones2, Michael Holland3, Cara Hoffart2, Maria Ibarra3 and Ashley Cooper2, 1Children's Mercy Kansas City, Overland Park, KS, 2Children's Mercy Kansas City, Kansas City, MO, 3Children's Mercy Hospital, Kansas City, MO

    Background/Purpose: Outcome assessment is essential to optimize care for patients with juvenile idiopathic arthritis (JIA). Although disease activity and patient-reported outcomes (PROs) are different measures,…
  • Abstract Number: 1509 • ACR Convergence 2025

    Outcome of Newly Diagnosed SLE with Serositis and Its Clinical Features in Daily Clinical Practice: A Single Center Study

    Shuzo Sato, Kaito Moriuchi, So Yamamoto, Hiroki Nibu, Takahito Sakamoto, Shotaro Ogawa, Kenji Saito, Yuya Sumichika, Shuhei Yoshida, Haruki Matsumoto, Jumpei Temmoku and Tomoyuki Asano, Fukushima Medical University, Fukushima, Fukushima, Japan

    Background/Purpose: Past reports have shown that serositis is a risk factor for organ damage in patients with SLE. However, the distinct clinical features of newly…
  • Abstract Number: 2703 • ACR Convergence 2025

    Longitudinal Changes on Cranial Magnetic Resonance Imaging in Relapsing Giant Cell Arteritis

    Ruoheng Zeng1, Ryan Rebello2, Konstanze Guggenberger3, Joshua Baker4, Shubhasree Banerjee4, Robert Kurtz4, Naomi Amudala4, Peter Merkel4 and Rennie Rhee4, 1University of Pennsylvania School of Medicine, Philadelphia, PA, 2St. Joseph’s Hospital at McMaster University, Hamilton, ON, Canada, 3University Hospital of Wuerzburg, Wuerzburg, Germany, 4University of Pennsylvania, Philadelphia, PA

    Background/Purpose: There is a need for better tools to monitor disease activity in giant cell arteritis (GCA). Prior studies demonstrated that vascular enhancement on cranial…
  • Abstract Number: 2404 • ACR Convergence 2025

    Clinical features of Elderly-onset Systemic Lupus Erythematosus

    Jessica Dai1, Erin Carter2, Mala Masson3, Amit Saxena4, H Michael Belmont5, Peter Izmirly6 and Jill Buyon4, 1New York University Grossman School of Medicine, Tenafly, NJ, 2New York University Grossman School of Medicine, New York, NY, 3NYU Langone Medical Center- Division of Rheumatology, New York, NY, 4NYU Grossman School of Medicine, New York, NY, 5NYU School of Medicine, New York, NY, 6New York University Grossman School of Medicine, New York, NY

    Background/Purpose: Systemic lupus erythematosus (SLE) is a multisystemic chronic disease characterized by a wide range of clinical and serological manifestations. It most commonly affects young…
  • Abstract Number: 2246 • ACR Convergence 2025

    Different Populations, Different SDAI Cut-Off? A Proposal for a New Remission Threshold in Brazilian RA Patients from a National Multicenter Study

    Lucas Pires1, Alisson Pugliesi1, Cleandro Pires2, Ana Carolina Hidaka3, Vitor Cruz4, Manoel Barros Bertolo1, Ana Paula Reis5, Rina Dalva Neubarth Giorgi6, Leticia Pereira7, Sebastião Cezar Radominski8, Ivanio Alves Pereira9, Maria Fernanda Brandão de Resende Guimarães10, Paulo Louzada Junior11, Maria de Fátima Lobato da Cunha Sauma12, Karina Bonfiglioli13, Claiton Viegas Brenol14, Licia Maria Henrique da Mota2 and Geraldo da Rocha Castelar Pinheiro7, 1Unicamp, Campinas, Brazil, 2UNB, Brasilia, Distrito Federal, Brazil, 3UNB, Brasilia, Brazil, 4UFG, Goias, Brazil, 5UniCEUB, Brasilia, Brazil, 6IAMSPE, São Paulo, Brazil, 7UERJ, Rio de Janeiro, Brazil, 8UFPR, Curitiba, Brazil, 9UFSC, Florianopolis, Brazil, 10UFMG, Belo Horizonte, Brazil, 11USP-RP, Ribeirão Preto, Brazil, 12UFPA, Belem, Brazil, 13USP-SP, São Paulo, Brazil, 14UFRGS, Porto Alegre, Brazil

    Background/Purpose: Remission criteria in Rheumatoid Arthritis (RA) have continuously evolved to balance the risks of both overtreatment and undertreatment. The most recent update includes the…
  • Abstract Number: 1661 • ACR Convergence 2025

    Artificial Intelligence applied to Patient Reported Outcomes and Passive Physiologic Sensor Data can Accurately Classify Low Disease Activity in Rheumatoid Arthritis Patients

    Jeffrey Curtis1, Yujie Su2, sam Barskiy3, Emily Holladay3, Shilpa Venkatachalam4, David Curtis5, Tapan Mehta3 and Fenglong Xie6, 1Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL, 2Foundation for Advancing Science, Technology, Education and Research (FASTER), Hoover, AL, 3University of Alabama at Birmingham, Birmingham, AL, 4Global Healthy Living Foundation, New York, NY, 5Global Healthy Living Foundation, Meriden, 6The University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Remote therapeutic monitoring (RTM) and remote physiologic monitoring (RPM) programs have the potential to capture data between clinical visits and provide information back to…
  • Abstract Number: 1430 • ACR Convergence 2025

    Redefining BASDAI cut-offs: implications for patients’ eligibility for initiating biologic disease-modifying antirheumatic treatment in axial spondyloarthritis

    Stylianos Georgiadis1, Lykke Ørnbjerg1, Brigitte Michelsen2, Tore K. Kvien2, Mehrdad Shoae Kazemi1, Bente Glintborg1, Anne Gitte Loft3, Rita Fonseca4, Helena Santos5, Andreas Reich6, Anne C. Regierer6, Jarno Rutanen7, Laura Kuusalo8, Gary Macfarlane9, Gareth T. Jones9, Adrian Ciurea10, Michael J. Nissen11, Bjorn Gudbjornsson12, Olafur Palsson13, Ziga Rotar14, Katja Perdan Pirkmajer15, Daniela Di Giuseppe16, Merete Hetland17 and Mikkel Ostergaard18, 1Rigshospitalet, Glostrup, Denmark, 2Diakonhjemmet Hospital, Oslo, Norway, 3Aarhus University Hospital, Aarhus, Denmark, 4Unidade Local de Saúde de Entre Douro e Vouga, Santa Maria da Feira, Portugal, 5Instituto Português de Reumatologia, Lisbon, Portugal, 6German Rheumatology Research Center, Berlin, Germany, 7Tampere University Hospital, Tampere, Finland, 8Turku University Hospital, Turku, Finland, 9University of Aberdeen, Aberdeen, United Kingdom, 10University Hospital Zurich, Zurich, Switzerland, 11Geneva University Hospital, Geneva, Switzerland, 12Landspitali University Hospital; Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 13University of Iceland, Reykjavik, Iceland, 14University Medical Centre Ljubljana, Ziri, Slovenia, 15University Medical Centre Ljubljana, Ljubljana, Slovenia, 16Karolinska Institutet, Department of Medicine Solna, Clinical Epidemiology Division, Stockholm, Stockholms Lan, Sweden, 17Copenhagen Center for Arthritis Research (COPECARE) and DANBIO, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup; Department of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark, 18Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark, and Copenhagen Center for Arthritis Research, Center for Rheumatology, Rigshospitalet, Glostrup, Denmark

    Background/Purpose: In patients with axial spondyloarthritis (axSpA), high disease activity is a key indication for biological disease-modifying antirheumatic drug (bDMARD) initiation. The Axial Spondyloarthritis Disease…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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