ACR Meeting Abstracts

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Abstracts tagged "Disease Activity"

  • Abstract Number: 0552 • ACR Convergence 2025

    Radiographic Sacroiliitis Progression in Psoriatic Arthritis

    Virginia Carrizo Abarza1, Pankti Mehta2, Fadi Kharouf3, Shangyi Gao4, Dafna D. Gladman5, Vinod Chandran6 and Denis Poddubnyy7, 1Toronto Western Hospital - University of Toronto, Toronto, ON, Canada, 2University of Toronto, Gladman Krembil Psoriatic Arthritis Research Program, Toronto, ON, Canada, 3University Health Network and University of Toronto, Toronto, ON, Canada, Toronto, ON, Canada, 4Gladman-Krembil Psoriatic Arthritis Research Program, Centre for Prognosis Studies in the Rheumatic Diseases, Schroeder Arthritis Institute, Krembil Research Institute, University Health Network, Toronto, Ontario, Canada, Toronto, ON, Canada, 5Schroeder Arthritis Institute, Krembil Research Institute, Toronto Western Hospital, Division of Rheumatology, Toronto, ON, Canada, 6University of Toronto, Toronto, ON, Canada, 7Division of Rheumatology, Department of Medicine, University Health Network and University of Toronto, Toronto, Ontario, Canada, and Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité – Universitätsmedizin Berlin, Berlin, Germany; Department of Epidemiology, German Rheumatism Research Centre, Berlin, Germany

    Background/Purpose: Radiographic sacroiliitis is an important indicator of axial involvement psoriatic arthritis (PsA), but only little is known about factors associated with progression of sacroiliitis.…
  • Abstract Number: 1212 • ACR Convergence 2025

    Relapse in Idiopathic Inflammatory Myopathies: insights from extended MyoCite and Italian Consortia

    Maria Rosa Pellico1, Cristina Bochicchio2, Claudia Iannone3, Lekshmi Minikumari Rahulan4, Marco Fornaro5, Ilaria Cavazzana6, Edoardo Conticini7, Masataka Kuwana8, Akira Yoshida9, Silvia Cavalli2, Silvia Grazzini7, Alessia Gatti10, Giulio Lopinto11, Paolo Semeraro12, Thomas Patrick Sheeran13, Florenzo Iannone14, Vikas Agarwal15, Roberto Caporali16, Nicoletta Del pAPA1 and Latika Gupta17, 1ASST Pini-CTO, Clinical Rheumatology Unit, Milano, Italy, 2ASST Pini-CTO, Clinical Rheumatology Unit, Milan, Italy, 3University of Milan, Gaetano Pini CTO, Milano, Milan, Italy, 4Sanjay Gandhi Postgraduate Institute of Medical sciences Lucknow, Lucknow, Uttar Pradesh, India, 5Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica (DiMePRe-J), University of Bari, Italy., Bari, Italy, 6Rheumatology and Clinical Immunology Unit, Clinical and Experimental Sciences Department, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Brescia, Italy, Brescia, Lombardia, Italy, 7Rheumatology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, Italy, Siena, Italy, 8Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 9Department of Allergy and Rheumatology Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 10Rheumatology and Clinical Immunology Unit – ERN ReCONNET, ASST Spedali Civili and University of Brescia, Brescia, Lombardia, Italy, 11Unit of Rheumatology, Department of Precision and Regenerative Medicine, Area Jonica (DiMePRe-J), University of Bari, Italy., Bari, 12Rheumatology and Clinical Immunology Unit, Clinical and Experimental Sciences Department, ERN ReCONNET, ASST Spedali Civili of Brescia and University of Brescia, Brescia, Italy, Brescia, Italy, 13Department of Rheumatology, The Royal Wolverhampton NHS Trust, Wolverhampton, UK; Rheumatology Department, Walsall Manor Hospital, Walsall, UK, Wolverhampton, United Kingdom, 14Rheumatology DiMePReJ, University of Bari, School of Medicine, Bari, Italy, Bari, Italy, 15Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 16University of Milan and ASST Gaetano Pini-CTO, Milano, Italy, 17School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom

    Background/Purpose: Idiopathic inflammatory myopathies (IIM) are a group of rare and heterogeneous diseases. One of the greatest challenges in IIM management is defining and predicting…
  • Abstract Number: 1410 • ACR Convergence 2025

    Examining the Interchangeability of Two Different Patient-Reported Global Assessment Measures in an Observational Axial Spondyloarthritis Cohort

    Connor Vershel1, Mark Hwang2, John Reveille3, Seokhun Kim4, Matthew A. Brown5, Michael Weisman6, Mariko Ishimori6 and Michael Ward7, 1Department of Internal Medicine, Division of Rheumatology, John P. and Katherine G. McGovern School of Medicine at the University of Texas Health Science Center at Houston, Houston, TX, 2UTHealth Houston, Houston, TX, 3Department of Medicine, University of Texas Medical Center, Houston, TX, 4UTHealth Houston, Houston, 5Genomics England, London, United Kingdom, 6Cedars-Sinai Medical Center, LOS ANGELES, CA, 7National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, US Department of Health and Human Services, Bethesda, MD

    Background/Purpose: In axial spondyloarthritis cohorts, patient reported outcomes are vital for tracking disease progression and response to therapy. However, many cohorts enrolled prior to the…
  • Abstract Number: 1533 • ACR Convergence 2025

    Belimumab Is Associated with Early Improvement in Disease Activity Measures Among Patients with Systemic Lupus Erythematosus in the US

    Yan Chen1, Maral DerSarkissian1, Shumin Rui1, Justin Clark1, Daniel Moldaver2, Jeffrey J. Ellis3, Karen Worley3 and Aarat M Patel4, 1Analysis Group, Los Angeles, CA, 2GSK, Global Real-World Evidence & Health Outcomes Research, Toronto, ON, Canada, 3GSK, Global Real-World Evidence & Health Outcomes Research, Collegeville, PA, 4GSK, US Medical Affairs, Durham, NC

    Background/Purpose: Belimumab (BEL), a B-cell modulator mAb that selectively inhibits soluble B-lymphocyte stimulator and reduces autoreactive B cells that drive lupus disease activity, is approved…
  • Abstract Number: 2096 • ACR Convergence 2025

    Gamification and Social Incentivization to Promote Physical Activity in Adults with Knee Osteoarthritis: Results from a Multi-Site Randomized Trial

    Kimberly Hayes1, Bryant England2, Katherine Wysham3, Mercedes Quinones4, Marianna Olave5, Sarah Wetzel6, Hannah Brubeck7, Rachel Gillcrist8, Criswell Lavery9, Natalie Keller10, Bibiana Ateh11, Bridget Kramer2, Rui Xiao9, Kaitian Jin9, Alexis Ogdie12, Daniel K. White13, Tuhina Neogi14, Carla Scanzello9 and Joshua Baker9, 1Teachers College, Columbia University, Philadelphia, PA, 2University of Nebraska Medical Center, Omaha, NE, 3VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA, 4Washington DC VA Medical Center, Bethesda, MD, 5Brown University, Philadelphia, PA, 6Drexel University, Pittsburgh, PA, 7VA Puget Sound Health Care System, Seattle, WA, 8Dartmouth College, Lebanon, NH, 9University of Pennsylvania, Philadelphia, PA, 10University of Oklahoma, Philadelphia, PA, 11Washington VA Medical Center, Washington, District of Columbia, 12Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Wilmington, DE, 13University of Delaware, Newark, DE, 14Boston University School of Medicine, Boston, MA

    Background/Purpose: Promotion of physical activity is important in the management of knee osteoarthritis (KOA), though effective strategies for behavioral change to promote exercise are lacking.…
  • Abstract Number: 2322 • ACR Convergence 2025

    Gender-related Differences in Peripheral and Axial Spondyloarthritis

    Mehmet Tuncay Duruöz1, Halise Hande Gezer1, İlknur Aktaş2, Servet Akar3, Nilay Şahin4, Özgür Akgül5, Sami Hizmetli6, Meltem Alkan Melikoğlu7, Umut Kalyoncu8, Erhan Çapkın9, fatma Gülçin Ural10, Figen Yılmaz11, Sebnem ATAMAN12 and İlhan Sezer13, 1Marmara University Medical School PMR Department, Rheumatology Division, Istanbul, Turkey, 2Istanbul Fatih Sultan Mehmet Training and Research Hospital, PMR, Turkey, Istanbul, Turkey, 3Department of Medicine, Izmir Katip Çelebi University School of Medicine, Izmir, Turkey, 4Balikesir University School of Medicine, PMR, Turkey, Balıkesir, Turkey, 5Manisa Celal Bayar University School of Medicine, Rheumatology, Turkey, Manisa, Turkey, 6Sivas Cumhuriyet University School of Medine, Rheumatology, Turkey, Sivas, Turkey, 7Erzurum Atatürk University School of Medicine, Rheumatology, Turkey, Erzurum, Turkey, 8Division of Rheumatology, Department of Internal Medicine, Hacettepe University School of Medicine, Ankara, Turkey, Ankara, Turkey, 9Karadeniz Teknik University School of Medicine, PMR, Turkey, Trabzon, Turkey, 10Ankara Yildirim Beyazit University School of Medicine, PMR, Turkey, Ankara, Turkey, 11Istanbul Sisli Etfal Training and Research Hospital, PMR, Turkey, Istanbul, Turkey, 12Ankara University School of Medicine, Rheumatology, Turkey, Ankara, Turkey, 13Akdeniz University School of Medicine, Rheumatology, Turkey, Antalya, Turkey

    Background/Purpose: This study sought to compare clinical characteristics between female and male patients with spondyloarthritis (SpA) in a Turkish population.Methods: This study included 489 peripheral…
  • Abstract Number: 2649 • ACR Convergence 2025

    Simultaneous Assessment of Complementary Lupus-Specific Immune Mediator-Informed Indexes Improves Their Ability to Concurrently Discern Current Disease Activity And Future Flare Risk In Systemic Lupus Erythematosus

    Melissa Munroe1, Derek Blankenship2, Daniele DeFreese2, Adrian Holloway2, Bernard Rubin2, Mohan Purushothaman2, Wade DeJager3, Susan Macwana4, Joel Guthridge4, Stan Kamp4, Nancy Redinger4, Teresa Aberle4, Eliza Chakravarty4, Cristina Arriens4, Yangfen Li5, Hu Zeng5, Stephanie Dezzutti6, Peter Izmirly7, Uma Thanarajasingam5, Diane Kamen8, Jill Buyon9, Judith James4 and Eldon Jupe2, 1Oklahoma Medical Research Foundation; Progentec Diagnostics, Inc., Oklahoma City, OK, 2Progentec Diagnostics, Inc., Oklahoma City, OK, 3Oklahoma Medical Research Foundation, Oklahoma City, 4Oklahoma Medical Research Foundation, Oklahoma City, OK, 5Mayo Clinic, Rochester, MN, 6Medical University of South Carolina, Charleston, SC, 7New York University Grossman School of Medicine, New York, NY, 8Medical University of South Carolina, Johns Island, SC, 9NYU Grossman School of Medicine, New York, NY

    Background/Purpose: Immune dysregulation propels systemic lupus erythematosus (SLE) pathogenesis. Capturing it as lab-based screening tests could help prioritize SLE patients for early intervention and proactive…
  • Abstract Number: 0385 • ACR Convergence 2025

    Musculoskeletal Ultrasound Enhances Patient Insight and Clinical Decisions: A Multi-Center Study

    Simran Nimal1, Meridith Balbach2, Aslam Fawad1, Midori Nishio3 and Erin Chew2, 1Mayo Clinic Arizona, Scottsdale, AZ, 2Vanderbilt University, Nashville, TN, 3John Muir Specialty Medical Group, Lafayette, CA

    Background/Purpose: Musculoskeletal ultrasound (MSKUS) is a valuable tool for early detection and management of inflammatory arthritis.(1) Although integrated into rheumatology guidelines, training programs, and classification…
  • Abstract Number: 0491 • ACR Convergence 2025

    Association of Short Chain Fatty Acids and Diet with Disease Activity and Methotrexate Response in New Onset Rheumatoid Arthritis: A Proof of Principle Study

    Kaci French1, Luz Alvarado2, Rebecca Haberman3 and Rebecca Blank3, 1NYU Langone, New York, NY, 2NYU Langone, New York, 3NYU Langone Health, New York, NY

    Background/Purpose: Diet, the gut microbiome, and gut microbial metabolites have been implicated in rheumatoid arthritis (RA) development and modulation. Seafood based-omega-3 fatty acids modulate inflammatory…
  • Abstract Number: 0580 • ACR Convergence 2025

    Persistence and Disease Activity Control among Patients with Psoriatic Arthritis in the CorEvitas Psoriatic Arthritis/Spondyloarthritis Registry Initiating a Third or Higher Line of Biologic or Targeted Synthetic Disease-Modifying Antirheumatic Drug Therapy

    Philip J. Mease1, Nicole Middaugh2, Yolanda Muñoz Maldonado2, Chao Song3, Melissa Eliot2, Robert Low3 and Alexis Ogdie4, 1Department of Rheumatology, Providence-Swedish Medical Center and University of Washington, Seattle, WA, 2CorEvitas, LLC, Waltham, MA, 3UCB, Smyrna, GA, 4University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Psoriatic arthritis (PsA) is a chronic disease that causes inflammation of the joints, entheses, spine, skin, and nails.1 While available advanced treatments (txs) for…
  • Abstract Number: 1218 • ACR Convergence 2025

    Social Determinants Shape Health Outcomes in Idiopathic Inflammatory Myopathies: Insights from Lived Experience of 1,252 Patients

    Tsvetelina Velikova1, Kostadin Kostadinov2, Emilia Naseva3, Tamar Rubinstein4, Manali Sarkar5, Lavanya Mangla6, Joanna Makowska7, Raphael Micheroli8, Leandro ferreryra9, Linda Kobert10, Ioannis Parodis11, Elena Nikiphorou12, Samuel Shinjo13, Carlo Vinicio Caballero Uribe14, Vincenzo Venerito15, Vikas Agarwal16 and Latika Gupta17, 1Medical Faculty, Sofia University St. Kliment Ohridski, Sofia, Bulgaria, 2Department of Social Medicine and Public Health, Faculty of Public Health, Medical University, Plovdiv; Health and Quality of Life in a Green and Sustainable Environment Research Group, Strategic Research and Innovation Program for the Development of MU- Plovdiv, Medical University of Plovdiv, Environmental Health Division, Research Institute at Medical University of Plovdiv, Medical University of Plovdiv,, Plovdiv, Bulgaria, 3Faculty of Public Health, Medical University of Sofia, 15 Acad. Ivan Evstratiev Geshov, 1606 Sofia; Medical Faculty, Sofia University St. Kliment Ohridski, Sofia, Bulgaria, 4Albert Einstein College of Medicine, White Plains, NY, 5Sir H. N. Reliance Foundation Hospital and Research Centre, Mumbai, Maharashtra, India., Mumbai, Maharashtra, India, 6Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, New Delhi, India, 7Department of Rheumatology, Medical University of Lodz, Lodz, Poland, 8University Hospital Zurich, Zurich, Switzerland, 9HIBA, CABA, Ciudad Autonoma de Buenos Aires, Argentina, 10The Myositis Association, Columbia, MD, 11Karolinska Institutet and Karolinska University Hospital, Department of Medicine Solna, Division of Rheumatology, Stockholm, Sweden, 12King's College London, London, United Kingdom, 13Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil, Sao Paulo, Brazil, 14Department of Medicine, Hospital Universidad del Norte, Barranquilla, Atlantico, Colombi, Barranquilla, Colombia, 15Univeristy of Bari "Aldo Moro", Italy, Bari, Bari, Italy, 16Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India, 17School of Infection, Inflammation and Immunology, College of Medicine and Health, University of Birmingham; Royal Wolverhampton NHS Trust; Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester; Francis Crick Institute, London, Birmingham, UK, United Kingdom

    Background/Purpose: The impact of social determinants of health (SDoH)—including socioeconomic status, social support, and geographic context—on disease outcomes in idiopathic inflammatory myopathies (IIM) remains underexplored.…
  • Abstract Number: 1411 • ACR Convergence 2025

    Defining Minimal Disease Activity (MDA) in Psoriatic Arthritis (PsA) with the inclusion of Psoriatic Arthritis Impact of Disease (PsAID) scores rather than Health Assessment Questionnaire (HAQ)

    Conor Coyle1, Sarah Yazji2, Sruthi Murthy3, Philip Helliwell4, Andra Balanescu5, Juan Cañete6, Emmanuelle Dernis7, Uta Kiltz8, Ying Ying Leung9, Ana-Maria Orbai10, PENELOPE PALOMINOS11, Josef Smolen12, Maarten de Wit13, Laure Gossec14 and Laura Coates15, 1Oxford University Hospitals, Reading, United Kingdom, 2South Texas Health System GME Consortium, Texas A&M College of Medicine, Texas, USA, College Station, TX, 3Oxford University Hospitals NHS Foundation Trust, Oxford, UK, Oxford, United Kingdom, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK, Leeds, United Kingdom, 5UNIVERSITY OF MEDICINE AND PHARMACY CAROL DAVILA, Bucharest, Romania, 6Rheumatology Department, Hospital Clínic and IDIBAPS, Barcelona, Spain, Barcelona, Spain, 7Rheumatology Department, Le Mans Central Hospital, Le Mans, France, LE MANS, France, 8Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Herne, Germany, 9Rheumatology Department, Singapore General Hospital, Singapore, Singapore, Singapore, Singapore, 10Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 11Hospital Lifeplus Litoral Norte,  Xangri-lá, Brazil, Porto Alegre, Rio Grande do Sul, Brazil, 12Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 13Patient Research Partner, Stichting Tools, Amsterdam, Netherlands, 14Sorbonne Universite and Pitie-Salpetriere Hospital, Paris, France, 15Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, England, United Kingdom

    Background/Purpose: Treat to target management is recommended in psoriatic arthritis (PsA) to improve disease control and patient quality of life. Minimal disease activity (MDA) criteria…
  • Abstract Number: 1536 • ACR Convergence 2025

    Evaluating Systemic Lupus Erythematosus Remission Among Patients Initiating Belimumab in a Real-World Setting in the USA

    Aarat M Patel1, Renee L. Gennarelli2, Temitope Bello2, Ali Bonakdar2 and Karen Worley3, 1GSK, US Medical Affairs, Durham, NC, 2Cencora, Real-World Evidence, Conshohocken, PA, 3GSK, Global Real-World Evidence & Health Outcomes Research, Collegeville, PA

    Background/Purpose: The Definition Of Remission In SLE (DORIS) criteria were developed to provide alignment on defining remission in patients with SLE.1,2 Belimumab (BEL) treatment increases…
  • Abstract Number: 2124 • ACR Convergence 2025

    Reliability and Validation of the Physician’s Global Assessment of Lung Disease (PGALD) in Systemic Juvenile Idiopathic Arthritis -Associated Lung Disease (SJIA-LD)

    Eileen Rife1, Guihua Zhai2, Mekibib Altaye3, Jennifer Andringa4, Hermine Brunner5, Scott Canna6, Lauren Henderson7, Yukiko Kimura8, Scott Lieberman9, Mona Riskalla10, Tiphanie Vogel11, Holly Wobma12 and Grant Schulert5, 1University of Alabama at Birmingham, birmingham, AL, 2UAB, Birmingham, 3Cincinnati Children's Hospital, Cincinnati, 4Cincinnati Children's Hospital Medical Center, Cincinnati, 5Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Children's Hospital of Philadelphia, Philadelphia, PA, 7Boston Children's Hospital, Watertown, MA, 8Hackensack Meridian School of Medicine, New York, NY, 9University of Iowa, Iowa City, IA, 10University of Minnesota Masonic Children's Hospital, Minneapolis, MN, 11Baylor College of Medicine, Houston, TX, 12Boston Children's Hospital, Boston, MA

    Background/Purpose: The physician global assessment of lung disease (PGALD) is a recently proposed disease activity measure for patients with systemic juvenile idiopathic arthritis-associated lung disease…
  • Abstract Number: 2332 • ACR Convergence 2025

    Development and validation of a Disease Activity index for PSoriatic Arthritis based on 44 joints: DAPSA44

    Dafne capelusnik1, Clementina López Medina2, Désirée Van Der Heijde3, Daniel Aletaha4, Josef Smolen5, Anna Molto6 and Sofia Ramiro7, 1Tel Aviv Sourasky Medical Center, Ramat Gan, Israel, 2Department of Medicine, Hospital Universitario Reina Sofia, University of Cordoba, IMIBIC, Cordoba, Spain, 3Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 4Medical University Vienna, Wien, Austria, 5Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Vienna, Austria, Vienna, Austria, 6Assistance Publique Hôpitauxde Paris, Paris, France, 7Leiden University Medical Center, Bunde, Netherlands

    Background/Purpose: Recent studies have highlighted the potential of composite scores such as the DAPSA for assessing peripheral arthritis in axSpA and pSpA. However, the swollen…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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