ACR Meeting Abstracts

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Abstracts tagged "Disease Activity"

  • Abstract Number: 0878 • ACR Convergence 2020

    Absolute Lymphocyte Count Is Negatively Correlated with Atherosclerotic Cardiovascular Disease Risk Score and Red Cell Distribution Width in Psoriatic Arthritis and Increases with TNF-Inhibitor Therapy

    Angela Gupta1, Sofi Damjanovska2, Alyssa Lange3, Brigid Wilson4, Taissa Bej4, Maya Mattar5, David Zidar6 and Donald Anthony7, 1(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, 2(1) Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, 3Case Western Reserve University, Cleveland, 4Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, 5Department of Medicine, VA Medical Center and VA GRECC, Case Western Reserve University, Cleveland OH, Cleveland, OH, 6Case Western Reserve University/Cleveland VA Medical Center, Cleveland, 7Case Western Reserve University/Cleveland VA Medical Center/MetroHealth Medical Center, Cleveland, OH

    Background/Purpose: Absolute lymphocyte count (ALC) is a parameter that represents the number of lymphocytes (B, T, and NK cells) in the blood, and lymphopenia often…
  • Abstract Number: 1152 • ACR Convergence 2020

    IL-18: A Biomarker That Reflects Disease Activity, Could It Be the Next Disease Activity Measure in Systemic Juvenile Idiopathic Arthritis?

    Shima Yasin1, Thuy Do2, Sanjeev Dhakal2, Elizabeth Baker2, Alexei Grom3 and Grant Schulert4, 1Cincinnati Children's Hospital Medical Center, Liberty twp, OH, 2Cincinnati Children's Hospital Medical Center, Cincinnati, 3Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4PRCSG, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Systemic juvenile idiopathic arthritis (sJIA) is a childhood arthritis with prominent innate immune activity. Disease presentation and flares could largely mimic infections with fever…
  • Abstract Number: 1291 • ACR Convergence 2020

    Depressed Symptomatology Persists over Time in the Majority of Systemic Lupus Erythematosus Patients and Is Independent of Disease Activity

    Sara Kellahan1, Xinliang Huang1, Daphne Lew2, Hong Xian3, Seth Eisen1 and Alfred Kim4, 1Division of Rheumatology, Washington University in St. Louis School of Medicine, St. Louis, 2Division of Biostatistics, Washington University in St. Louis School of Medicine, St. Louis, 3Department of Epidemiology and Biostatistics, College for Public Health and Social Justice, Saint Louis University, St. Louis, 4Washington University School of Medicine, St. Louis, MO

    Background/Purpose: Depression is a prevalent (24-30%) and significant comorbidity in patients with systemic lupus erythematosus (SLE) (1).  As the American College of Rheumatology (ACR) classifies…
  • Abstract Number: 1549 • ACR Convergence 2020

    Joint Damage and Malalignment Determine Articular Tenderness More Than Inflammation in Rheumatoid Arthritis, Psoriatic Arthritis or Osteoarthritis in Established Disease

    Mihaela Popescu1, Victoria Schimpl2, Gabriela Supp3, Martina Durechova3, Paul Studenic3, Michael Zauner3, Josef Smolen3, Daniel Aletaha4, Peter Mandl3 and Irina Gessl3, 1Hôpital Maisonneuve-Rosemont, Montreal, Canada, 2Medical University of Vienna, Vienna, Austria, 3Division of Rheumatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria, 4Division of Rheumatology, Department of Medicine III, Medical University of Vienna,, Vienna, Austria

    Background/Purpose: To determine whether clinical tenderness can be considered a sign of inflammatory joint activity in patients with rheumatoid arthritis (RA), osteoarthritis (OA) or psoriatic…
  • Abstract Number: 1738 • ACR Convergence 2020

    Promote Treat-to-Target for RA via Empowering Patients: A Cohort Study from China by Smart System of Disease Management (SSDM)

    Jing Yang1, Rong Mu2, Chun Li3, Bin Wu4, Hongzhi Wang5, Wenqiang Fan6, Jinmei Zou7, Yu Zhang1, Fen Li8, Xiaofeng Rong9, Jianhong Wu10, Yong Wang11, Shengguang Li12, Yi Zhao13, Xiaoqiang Hou14, Hui Xiao15, Yuhua Jia16, Bing Wu16, Miaomiao Song16, Fei Xiao16 and Zhanguo Li17, 1Department of Rheumatology, Mianyang Central Hospital, Mianyang, China (People's Republic), 2People's Hospital, Beijing University Medical School, Beijing, Beijing, China (People's Republic), 3People's Hospital, Beijing University Medical School, beijing, China (People's Republic), 4Chongqing Hospital of Traditional Chinese Medicine, chongqing, China (People's Republic), 5The First Hospital of Jiaxing, Jiaxing, China (People's Republic), 6Central Hospital of XinXiang, Xinxiang, China (People's Republic), 7Department of Rheumatology, Mianyang Central Hospital, Mianyang, Sichuan, China (People's Republic), 8The Second Xiangya Hospital of Central South University, hunan, China (People's Republic), 9The First Affiliated Hospital of Chongqing Medical University, chongqing, China (People's Republic), 10Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), 11The first Hospital Affiliated to AMU (Southernwest Hospital), chongqing, China (People's Republic), 12Peking University International Hospital, Beijing, China (People's Republic), 13Xuanwu Hospital, Capital Medical University, Beijing, China, Beijing, China (People's Republic), 14Yichang Central People's Hospital, Beijing, China (People's Republic), 15Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 16Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 17Peking University People’s Hospital, Xicheng, Beijing, China (People's Republic)

    Background/Purpose: Treat-to-Target (T2T) strategy are critical for the treatment of RA, but Chinese rheumatologists can hardly provide patients with a complete assessment in the clinic…
  • Abstract Number: 1853 • ACR Convergence 2020

    Association of Gut Dysbiosis with Radiographic and Enthesis Involvement, Disease Activity and Duration in Axial Spondyloarthritis. Data from CASTRO Registry

    Ignacio Gómez-García1, Isabel Moreno-Indias2, María-Carmen Abalos-Aguilera1, Clementina Lopez-Medina3, Lourdes Ladehesa-Pineda4, Concepción Aranda-Valera4, Carolina Gutierrez-Repiso2, Yolanda Jimenez-Gomez5, Nuria Barbarroja1, Chary Lopez-Pedrera1, Francisco-Jose Tinahones2, Eduardo Collantes-Estévez4, Alejandro Escudero-Contreras4 and Patricia Ruiz-Limon6, 1Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, 2Biomedical Research Institute of Malaga (IBIMA)/ Endocrinology and Nutrition Department, Virgen de la Victoria Hospital, Malaga, Spain/ CIBER Fisiopatología de la Obesidad y Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain, Malaga, Spain, 3Rheumatology Department, Cochin Hospital, Paris, Paris, France, 4Rheumatology Department, Reina Sofia University Hospital/ Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Córdoba, Spain, 5Maimonides Institute for Research in Biomedicine of Cordoba (IMIBIC)/ University of Cordoba, Cordoba, Spain, Cordoba, Spain, 6Biomedical Research Institute of Málaga (IBIMA)/ Endocrinology and Nutrition Department, Virgen de la Victoria Hospital, Malaga, Spain, Malaga, Spain

    Background/Purpose: The etiopathogenesis of axial spondyloarthritis (AxSpA) is multifactorial. The possible role of alteration in gut microbiome (dysbiosis) has been recently suggested. However, the association…
  • Abstract Number: 0022 • ACR Convergence 2020

    Association Between Changes in Pain Sensitization and Changes in Disease Activity After 12 Weeks of Disease Modifying Anti-Rheumatic Drug Therapy in Rheumatoid Arthritis

    Andrew Heisler1, Jing Song2, Lutfiyya Muhammad3, Alyssa Wohlfahrt4, Wendy Marder5, Marcy Bolster6, Clifton Bingham III7, Daniel Clauw8, Dorothy Dunlop9, Tuhina Neogi10 and Yvonne Lee3, 1Northwestern University Feinberg School of Medicine, Oak Park, IL, 2Northwestern University, Chicago, 3Northwestern University Feinberg School of Medicine, Chicago, IL, 4Brigham and Womans Hospital, Boston, MA, 5University of Michigan, Ann Arbor, MI, 6Massachusetts General Hospital, Concord, MA, 7Johns Hopkins University, Baltimore, MD, 8Michigan Medicine, Ann Arbor, MI, 9Northwestern University, New Haven, CT, 10Boston University School of Medicine, Boston, MA

    Background/Purpose: Patients with rheumatoid arthritis (RA) have abnormalities in central nervous system regulation of pain, leading to enhanced pain sensitivity at joint sites (peripheral sensitization)…
  • Abstract Number: 0254 • ACR Convergence 2020

    LLDAS (Low Lupus Disease Activity State) and Remission Prevent Damage Accrual in Systemic Lupus Erythematosus (SLE) Patients in a Primarily Mestizo Cohort

    Manuel Ugarte-Gil1, Rocío V. Gamboa-Cárdenas2, Cristina Reátegui-Sokolova3, Victor Pimentel-Quiroz4, Mariela Medina2, Claudia Elera-Fitzcarrald4, Francisco Zevallos2, César A. Pastor-Asurza5, Jennifer Lofland6, Federico Zazzetti7, Chetan Karyekar8, Graciela Alarcón9 and Risto Perich-Campos5, 1Department of Rheumatology, Hospital Nacional Guillermo Almenara Irigoyen. EsSalud; Universidad Científica del Sur, Lima, Peru, 2Department of Rheumatology. Hospital Nacional Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, 3Hospital Guillermo Almenara Irigoyen; Universidad San Ignacio de Loyola, Lima, Peru, 4Department of Rheumatology. Hospital Nacional Guillermo Almenara Irigoyen. EsSalud; Universidad Científica del Sur, Lima, Peru, 5Department of Rheumatology. Hospital Nacional Guillermo Almenara Irigoyen. EsSalud; Universidad Nacional Mayor de San Marcos, Lima, Peru, 6Global Commercial Strategic Organisation, Johnson and Johnson, Horsham, PA, 7Janssen Scientific Affairs, LLC, Buenos Aires, Argentina, 8Janssen Global Services, LLC, Horsham, PA, 9Division of Clinical Immunology and Rheumatology, Department of Medicine, School of Medicine, The University of Alabama at Birmingham; Department of Medicine, School of Medicine; Universidad Peruana Cayetano, Heredia, Alabama

    Background/Purpose: LLDAS and remission have been proposed as treatment goals for SLE patients. However, their impact on damage prevention in patients from Latin America has…
  • Abstract Number: 0377 • ACR Convergence 2020

    Evaluation of Sex Differences in the Efficacy and Safety of Tofacitinib in Patients with Active Psoriatic Arthritis: A Post Hoc Analysis of Two Phase 3 Randomized Controlled Trials

    Lihi Eder1, Dafna Gladman2, Sibel Zehra Aydin3, Alexis Ogdie4, Harry Shi5, Pierre-Alexandre Landry6 and Rayana Luna6, 1Women’s College Research Institute, University of Toronto, Toronto, ON, Canada, 2Krembil Research Institute, Toronto Western Hospital, Toronto, ON, Canada, 3Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada, 4Division of Rheumatology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 5Pfizer Inc, Collegeville, PA, 6Pfizer Canada ULC, Kirkland, Canada

    Background/Purpose: Studies indicate that sex (male vs female) is predictive of outcomes with PsA treatments, such as TNF inhibitors (TNFi).1 Tofacitinib is an oral JAK…
  • Abstract Number: 0752 • ACR Convergence 2020

    Serum Proteomics Implicates Neutrophil Degranulation in Rheumatoid Arthritis Disease Activity

    Liam O'Neil1, Vidyanand Anaparti1, Dana Wiens1, Irene Smolik1, Xiaobo Meng1 and Hani El-Gabalawy1, 1University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: Though targeted therapeutics have improved outcomes in Rheumatoid Arthritis (RA) treatment, the understanding of the underlying biological mechanisms that mediate inflammatory arthritis in RA…
  • Abstract Number: 0881 • ACR Convergence 2020

    Reduction of Anterior Uveitis Flares in Patients with Axial Spondyloarthritis During Certolizumab Pegol Treatment: 96-Week Results from the C-VIEW Study

    Irene van der Horst-Bruinsma1, Rianne van Bentum1, Frank Verbraak2, Thomas Rath3, James Rosenbaum4, Bengt Hoepken5, Oscar Irvin-Sellers6, Thomas Kumke5, Lars Bauer5 and Martin Rudwaleit7, 1Department of Rheumatology, Amsterdam UMC, location VU University Medical Centre, Amsterdam, Netherlands, 2Amsterdam UMC, location VU University Medical Centre, Amsterdam, Netherlands, 3St Franziskus-Hospital, Münster, Germany, 4Oregon Health & Science University, Portland, OR, 5UCB Pharma, Monheim am Rhein, Germany, 6UCB Pharma, Slough, United Kingdom, 7Department of Internal Medicine and Rheumatology, Klinikum Bielefeld, Germany

    Background/Purpose: Acute anterior uveitis (AAU) is the most common extra-articular manifestation in axial spondyloarthritis (axSpA), affecting up to 40% of patients and causing significant burden.1…
  • Abstract Number: 1157 • ACR Convergence 2020

    Health and Socioeconomic Outcomes in a Neonatal-Onset Multisystem Inflammatory Disease (NOMID) Cohort Followed for a Median of Fifteen Years

    Sara Alehashemi1, Megha Garg2, Kim Johnson3, Kelly King4, Chris Zalewski4, Debbie Payne5, Adriana de Jesus6, Joseph Snow7, Wadih Zein5, M. Teresa Magone5, Rachel Bishop8, Carmen Brewer4, Jeff Kim4, Scott Paul9, John Butman10 and Raphaela Goldbach-Mansky11, 1Translational Autoinflammatory Disease Section (TADS)/NIAID/NIH, Clarksville, MD, 2NIH/NIAID, Rochester, NY, 3NIH, NIAID, Bethesda, 4NIH, NIDCD, Bethesda, MD, 5NIH/NEI, Bethesda, MD, 6Translational Autoinflammatory Disease Section (TADS)/NIAID/NIH, Silver Spring, MD, 7NIH, NIMH, Bethesda, MD, 8NIH, NEI, Bethesda, MD, 9NIH, CC/RMD, Bethesda, MD, 10NIH, CC/DRD, Bethesa, MD, 11Translational Autoinflammatory Disease Section (TADS)/NIAID/NIH, Potomac, MD

    Background/Purpose: Patients (pts) with NOMID have systemic inflammation and organ damage such as sensorineural hearing loss, hydrocephalus, optic nerve atrophy and growth plate defects. IL-1 blocking…
  • Abstract Number: 1295 • ACR Convergence 2020

    Disease Activity and Mental Health in SLE Patients: A Cross-section Study with Self-Assessments Based on Smart System of Disease Management (SSDM) Mobile Tools

    Yongfu Wang1, Hua Wei2, Rui Wu3, Jianhong Wu4, Shengtao Zhang5, Qin Li6, Yang Li7, You Sun7, Yanping Zhao8, Qiang Shu9, Lirong Kang1, Bin Wu10, Li Qin11, Feng Jiang11, Huiqin Yang12, Junli Zhang13, Hui Xiao14, Bing Wu15, Yuhua Jia15, Fei Xiao15 and Lingyun Sun16, 1The First Affiliated Hospital of BaoTou Medical College, Inner Mongolia University of Science and Technology, Baotou, China (People's Republic), 2Northern Jiangsu People's Hospital, Yangzhou, China (People's Republic), 3The First Affiliated Hospital of Nanchang University, Nanchang, China (People's Republic), 4Department of Rheumatology, Dazhou Central Hospital, Dazhou, China (People's Republic), 5Tongji Hospital Affiliated Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China (People's Republic), 6The First People's Hospital of Yunnan Province, Kunming, China (People's Republic), 7The Second Affiliated Hospital of Harbin Medical University, Harbin, China (People's Republic), 8First Affiliated Hospital of Harbin Medical University, Harbin, China (People's Republic), 9Qilu Hospital of Shandong University, Jinan, China (People's Republic), 10The First People's Hospital of Jingzhou, Jingzhou, China (People's Republic), 11The No.3 People’s Hospital of HuZhou City, Huzhou, China (People's Republic), 12Wuhan No. 1 Hospital, Wuhan, China (People's Republic), 13Xi'an No. 5 Hospital, Xi'an, China (People's Republic), 14Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), 15Shanghai Gothic Internet Technology Co., Ltd., Shanghai, China (People's Republic), 16Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China (People's Republic)

    Background/Purpose: WHO survey showed that the prevalence of anxiety and depression in Chinese population and Chinese patients with chronic diseases were between 3.1% - 4.2%…
  • Abstract Number: 1595 • ACR Convergence 2020

    Using Rheumatoid Arthritis Communication Tool Developed by the RISE Learning Collaborative to Promote Shared Decision-Making

    Joad Eseddi1, Puneet Bajaj2, Gabriela Schmajuk3, Jinoos Yazdany4 and Salahuddin Kazi5, 1UT Southwestern Medical Center, Dallas, TX, 2UT Southwestern, Dallas, TX, 3University of California, San Francisco, Atherton, CA, 4University of California, San Francisco, San Francisco, CA, 5Veterans Affairs North Texas Healthcare System / UT Southwestern Medical Center, Dallas, TX

    Background/Purpose: Patient care is moving from physician directed treatment to a co-design framework that focuses on creating a partnership between patients and physicians. This new…
  • Abstract Number: 1746 • ACR Convergence 2020

    Association of Obesity with Treatment Response to Methotrexate or Tumor Necrosis Factor Inhibitors in Patients with Rheumatoid Arthritis

    Dilli Poudel1, Ted Mikuls2, Michael George1, Bryant England2, Grant Cannon3, Brian Sauer4 and Joshua Baker1, 1University of Pennsylvania, Philadelphia, PA, 2University of Nebraska Medical Center, Omaha, NE, 3Salt Lake City VA Medical Center and University of Utah, Salt Lake City, 4University of Utah, Omaha, NE

    Background/Purpose: Obesity affects 30-40% of RA patients and is associated with higher clinical disease activity measures and progressive disability. Studies suggest that obesity may be…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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